Regina Fluhrer

3.2k total citations
51 papers, 2.5k citations indexed

About

Regina Fluhrer is a scholar working on Molecular Biology, Oncology and Physiology. According to data from OpenAlex, Regina Fluhrer has authored 51 papers receiving a total of 2.5k indexed citations (citations by other indexed papers that have themselves been cited), including 32 papers in Molecular Biology, 30 papers in Oncology and 16 papers in Physiology. Recurrent topics in Regina Fluhrer's work include Peptidase Inhibition and Analysis (24 papers), Alzheimer's disease research and treatments (15 papers) and Cellular transport and secretion (14 papers). Regina Fluhrer is often cited by papers focused on Peptidase Inhibition and Analysis (24 papers), Alzheimer's disease research and treatments (15 papers) and Cellular transport and secretion (14 papers). Regina Fluhrer collaborates with scholars based in Germany, United States and United Kingdom. Regina Fluhrer's co-authors include Christian Haass, Harald Steiner, Bernd Schröder, Stefan F. Lichtenthaler, Marius K. Lemberg, Jochen Walter, Matthias Voß, Anja Capell, Michael Willem and Paul Säftig and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Nature Communications.

In The Last Decade

Regina Fluhrer

51 papers receiving 2.5k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Regina Fluhrer Germany 30 1.5k 948 653 652 344 51 2.5k
David A. Lomas United Kingdom 22 1.2k 0.8× 777 0.8× 525 0.8× 402 0.6× 155 0.5× 32 2.6k
Astrid Kehlen Germany 32 1.3k 0.9× 431 0.5× 219 0.3× 762 1.2× 448 1.3× 71 2.9k
Yuichi Morohashi Japan 23 1.5k 1.0× 856 0.9× 559 0.9× 185 0.3× 133 0.4× 33 2.3k
Elena Miranda Italy 29 2.1k 1.4× 602 0.6× 1.0k 1.6× 524 0.8× 253 0.7× 84 3.8k
Yi-Heng Hao United States 10 1.1k 0.7× 678 0.7× 381 0.6× 168 0.3× 119 0.3× 10 1.7k
Ronald R. Hiebsch United States 20 790 0.5× 586 0.6× 323 0.5× 172 0.3× 396 1.2× 33 1.6k
Nicholas A. Morrice United Kingdom 36 3.3k 2.2× 316 0.3× 653 1.0× 657 1.0× 432 1.3× 64 4.2k
Michael Luther United States 22 1.4k 1.0× 286 0.3× 521 0.8× 762 1.2× 467 1.4× 37 3.0k
James A. Cromlish Canada 19 1.7k 1.2× 334 0.4× 507 0.8× 445 0.7× 365 1.1× 27 2.6k
Ute Preuß Germany 19 1.5k 1.0× 585 0.6× 719 1.1× 295 0.5× 105 0.3× 28 2.1k

Countries citing papers authored by Regina Fluhrer

Since Specialization
Citations

This map shows the geographic impact of Regina Fluhrer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Regina Fluhrer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Regina Fluhrer more than expected).

Fields of papers citing papers by Regina Fluhrer

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Regina Fluhrer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Regina Fluhrer. The network helps show where Regina Fluhrer may publish in the future.

Co-authorship network of co-authors of Regina Fluhrer

This figure shows the co-authorship network connecting the top 25 collaborators of Regina Fluhrer. A scholar is included among the top collaborators of Regina Fluhrer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Regina Fluhrer. Regina Fluhrer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Schlosser, Christine, et al.. (2024). In vitro cleavage of tumor necrosis factor α (TNFα) by Signal-Peptide-Peptidase-like 2b (SPPL2b) resembles mechanistic principles observed in the cellular context. Chemico-Biological Interactions. 395. 111006–111006. 1 indexed citations
2.
Mentrup, Torben, et al.. (2023). The role of SPP/SPPL intramembrane proteases in membrane protein homeostasis. FEBS Journal. 291(1). 25–44. 5 indexed citations
3.
Schröder, Bernd, et al.. (2023). Structure and function of SPP/SPPL proteases: insights from biochemical evidence and predictive modeling. FEBS Journal. 290(23). 5456–5474. 5 indexed citations
4.
Heard, Amanda, John M. Warrington, John Lattin, et al.. (2022). Antigen glycosylation regulates efficacy of CAR T cells targeting CD19. Nature Communications. 13(1). 3367–3367. 40 indexed citations
5.
Stelzer, Walter, Christine Schlosser, Charlotte Spitz, et al.. (2022). Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage. Scientific Reports. 12(1). 20987–20987. 8 indexed citations
6.
Spitz, Charlotte, Christine Schlosser, Walter Stelzer, et al.. (2020). Non-canonical Shedding of TNFα by SPPL2a Is Determined by the Conformational Flexibility of Its Transmembrane Helix. iScience. 23(12). 101775–101775. 16 indexed citations
7.
Brugger, Manuel S., et al.. (2020). Vibration enhanced cell growth induced by surface acoustic waves as in vitro wound-healing model. Proceedings of the National Academy of Sciences. 117(50). 31603–31613. 29 indexed citations
8.
Müller, Stephan A., Torben Mentrup, Merav D. Shmueli, et al.. (2019). Signal peptide peptidase‐like 2c impairs vesicular transport and cleaves SNARE proteins. EMBO Reports. 20(3). 31 indexed citations
9.
Mentrup, Torben, Stephan A. Müller, Verena Dederer, et al.. (2019). The intramembrane protease SPPL 2c promotes male germ cell development by cleaving phospholamban. EMBO Reports. 20(3). 29 indexed citations
10.
Mazzaferri, Javier, et al.. (2017). CLN5 is cleaved by members of the SPP/SPPL family to produce a mature soluble protein. Experimental Cell Research. 357(1). 40–50. 26 indexed citations
11.
Voß, Matthias, Bernd Schröder, & Regina Fluhrer. (2013). Mechanism, specificity, and physiology of signal peptide peptidase (SPP) and SPP-like proteases. Biochimica et Biophysica Acta (BBA) - Biomembranes. 1828(12). 2828–2839. 108 indexed citations
12.
Poggi, Marjorie, Jean Michel Brunel, Jean‐François Landrier, et al.. (2012). Palmitoylation of TNF alpha is involved in the regulation of TNF receptor 1 signalling. Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1833(3). 602–612. 38 indexed citations
13.
Fukumori, Akio, Regina Fluhrer, Harald Steiner, & Ch. Haass. (2010). Three-Amino Acid Spacing of Presenilin Endoproteolysis Suggests a General Stepwise Cleavage of  -Secretase-Mediated Intramembrane Proteolysis. Journal of Neuroscience. 30(23). 7853–7862. 81 indexed citations
14.
Prager, Kai, Lihua Wang‐Eckhardt, Regina Fluhrer, et al.. (2007). A Structural Switch of Presenilin 1 by Glycogen Synthase Kinase 3β-mediated Phosphorylation Regulates the Interaction with β-Catenin and Its Nuclear Signaling. Journal of Biological Chemistry. 282(19). 14083–14093. 23 indexed citations
15.
Fluhrer, Regina, Lars Israel, Margaret M. Condron, et al.. (2006). A γ-secretase-like intramembrane cleavage of TNFα by the GxGD aspartyl protease SPPL2b. Nature Cell Biology. 8(8). 894–896. 115 indexed citations
16.
Krawitz, Peter, Christof Haffner, Regina Fluhrer, et al.. (2005). Differential Localization and Identification of a Critical Aspartate Suggest Non-redundant Proteolytic Functions of the Presenilin Homologues SPPL2b and SPPL3. Journal of Biological Chemistry. 280(47). 39515–39523. 73 indexed citations
17.
Fluhrer, Regina, Arno Friedlein, Christian Haass, & Jochen Walter. (2004). Phosphorylation of Presenilin 1 at the Caspase Recognition Site Regulates Its Proteolytic Processing and the Progression of Apoptosis. Journal of Biological Chemistry. 279(3). 1585–1593. 51 indexed citations
18.
Fluhrer, Regina, Gerd Multhaup, Andrea Schlicksupp, et al.. (2003). Identification of a β-Secretase Activity, Which Truncates Amyloid β-Peptide after Its Presenilin-dependent Generation. Journal of Biological Chemistry. 278(8). 5531–5538. 64 indexed citations
19.
Fluhrer, Regina, Anja Capell, Gil G. Westmeyer, et al.. (2002). A non‐amyloidogenic function of BACE‐2 in the secretory pathway. Journal of Neurochemistry. 81(5). 1011–1020. 87 indexed citations
20.
Capell, Anja, Liane Meyn, Regina Fluhrer, et al.. (2002). Apical Sorting of β-Secretase Limits Amyloid β-Peptide Production. Journal of Biological Chemistry. 277(7). 5637–5643. 58 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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