R. C. Simsiman

1.4k total citations · 1 hit paper
17 papers, 1.2k citations indexed

About

R. C. Simsiman is a scholar working on Molecular Biology, Biochemistry and Pharmacology. According to data from OpenAlex, R. C. Simsiman has authored 17 papers receiving a total of 1.2k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 7 papers in Biochemistry and 3 papers in Pharmacology. Recurrent topics in R. C. Simsiman's work include Polyamine Metabolism and Applications (10 papers), Amino Acid Enzymes and Metabolism (7 papers) and Microbial Natural Products and Biosynthesis (2 papers). R. C. Simsiman is often cited by papers focused on Polyamine Metabolism and Applications (10 papers), Amino Acid Enzymes and Metabolism (7 papers) and Microbial Natural Products and Biosynthesis (2 papers). R. C. Simsiman collaborates with scholars based in United States, Japan and South Korea. R. C. Simsiman's co-authors include R. K. Boutwell, Thomas G. O’Brien, Ajit Kumar Verma, Masaharu Takigawa, R. Allan Mufson, R. Raineri, Jing Zou, Ching‐Ping Tseng, H Ahrens and Peter J. Reddig and has published in prestigious journals such as Proceedings of the National Academy of Sciences, JNCI Journal of the National Cancer Institute and Biochemical and Biophysical Research Communications.

In The Last Decade

R. C. Simsiman

17 papers receiving 1.1k citations

Hit Papers

1 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.

1975 442 citations Thomas G. O’Brien, R. C. Simsiman et al. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich) profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
R. C. Simsiman United States	14	974	396	150	132	106	17	1.2k
T.J. Slaga United States	20	949 1.0×	107 0.3×	523 3.5×	112 0.8×	269 2.5×	44	1.7k
M H Wiley United States	16	560 0.6×	164 0.4×	130 0.9×	73 0.6×	61 0.6×	26	903
Harry W. Chen United States	15	1.2k 1.2×	273 0.7×	188 1.3×	110 0.8×	174 1.6×	19	1.8k
B. Sorg Germany	19	577 0.6×	80 0.2×	128 0.9×	40 0.3×	85 0.8×	55	1.0k
G. E. Milo United States	16	402 0.4×	173 0.4×	127 0.8×	54 0.4×	117 1.1×	35	956
Aurora Viaje United States	19	511 0.5×	54 0.1×	380 2.5×	76 0.6×	137 1.3×	35	940
Diels J. van den Dobbelsteen Sweden	9	669 0.7×	158 0.4×	101 0.7×	48 0.4×	205 1.9×	13	1.1k
Shuichi Furuta Japan	20	962 1.0×	130 0.3×	125 0.8×	163 1.2×	74 0.7×	31	1.4k
Ludovica Gabriel Italy	16	575 0.6×	108 0.3×	170 1.1×	64 0.5×	88 0.8×	46	984
Sam Sorof United States	20	639 0.7×	86 0.2×	250 1.7×	84 0.6×	321 3.0×	54	1.2k

Countries citing papers authored by R. C. Simsiman

Since Specialization

Citations

This map shows the geographic impact of R. C. Simsiman's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. C. Simsiman with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. C. Simsiman more than expected).

Fields of papers citing papers by R. C. Simsiman

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. C. Simsiman. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. C. Simsiman. The network helps show where R. C. Simsiman may publish in the future.

Co-authorship network of co-authors of R. C. Simsiman

This figure shows the co-authorship network connecting the top 25 collaborators of R. C. Simsiman. A scholar is included among the top collaborators of R. C. Simsiman based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with R. C. Simsiman. R. C. Simsiman is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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17 of 17 papers shown

Messing, Edward M., Richard R. Love, K D Tutsch, et al.. (1999). Low-Dose Difluoromethylornithine and Polyamine Levels in Human Prostate Tissue. JNCI Journal of the National Cancer Institute. 91(16). 1416–1417. 15 indexed citations

Reddig, Peter J., H Ahrens, R. C. Simsiman, et al.. (1999). Transgenic mice overexpressing protein kinase Cdelta in the epidermis are resistant to skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate.. PubMed. 59(22). 5710–8. 128 indexed citations

Han, Kyungja, Wonbae Lee, Charles P. Harris, et al.. (1994). Comparison of chromosome aberrations in leiomyoma and leiomyosarcoma using FISH on archival tissues. Cancer Genetics and Cytogenetics. 74(1). 19–24. 30 indexed citations

Simsiman, R. C., et al.. (1986). The role of prostaglandin E1 in ornithine decarboxylase induction by tumor promoters. International Journal of Cancer. 37(3). 445–449. 2 indexed citations

Takigawa, Masaharu, R. C. Simsiman, & R. K. Boutwell. (1986). Tumor promoter-induced refractory state against ornithine decarboxylase induction by 12-O-tetradecanoylphorbol-13-acetate in mouse epidermis.. PubMed. 46(1). 106–12. 15 indexed citations

Takigawa, Masaharu, R. C. Simsiman, & R. K. Boutwell. (1983). The difference between the effects of single and double applications of 12-O-tetradecanoylphorbol-13-acetate, a potent tumor promoter, on polyamine metabolism and nucleic acid synthesis in mouse epidermis. Carcinogenesis. 4(1). 5–7. 14 indexed citations

Takigawa, Masaharu, Ajit Kumar Verma, R. C. Simsiman, & R. K. Boutwell. (1983). Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by alpha-difluoromethylornithine.. PubMed. 43(8). 3732–8. 88 indexed citations

Takigawa, Masaharu, Ajit Kumar Verma, R. C. Simsiman, & R. K. Boutwell. (1982). Polyamine biosynthesis and skin tumor promotion: Inhibition of 12-0-tetradecanoylphorbol-13-acetate-promoted mouse skin tumor formation by the irreversible inhibitor of ornithine decarboxylase α-difluoromethylornithine. Biochemical and Biophysical Research Communications. 105(3). 969–976. 80 indexed citations

Mufson, R. Allan, R. C. Simsiman, & R. K. Boutwell. (1979). Increased cyclic adenosine 3':5'-monophosphate phosphodiesterase activity in the epidermis of phorbol ester-treated mouse skin and in papillomas.. PubMed. 39(6 Pt 1). 2036–40. 13 indexed citations

10.

Raineri, R., R. C. Simsiman, & R. K. Boutwell. (1978). Stimulation of the synthesis of the H1 and H3 histone fractions of mouse epidermis by 12-O-tetradecanoylphorbol-13-acetate. Cancer Letters. 5(5). 277–284. 5 indexed citations

11.

Mufson, R. Allan, R. C. Simsiman, & R. K. Boutwell. (1977). The effect of the phorbol ester tumor promoters on the basal and catecholamine-stimulated levels of cyclic adenosine 3':5'-monophosphate in mouse skin and epidermis in vivo.. PubMed. 37(3). 665–9. 63 indexed citations

12.

Raineri, R., R. C. Simsiman, & R. K. Boutwell. (1977). Stimulation of the synthesis of mouse epidermal histones by tumor-promoting agents.. PubMed. 37(12). 4584–9. 8 indexed citations

13.

Mufson, R. Allan, et al.. (1977). Dissociation of increases in levels of 3':5'-cyclic AMP and 3':5'-cyclic GMP from induction of ornithine decarboxylase by the tumor promoter 12-O-tetradecanoyl phorbol-13-acetate in mouse epidermis in vivo.. Proceedings of the National Academy of Sciences. 74(2). 657–661. 28 indexed citations

14.

Simsiman, R. C., et al.. (1976). The effect of colchicine on the induction of ornithine decarboxylase by 12-O-tetradecanoyl-phorbol-13-acetate.. PubMed. 36(10). 3766–70. 26 indexed citations

15.

O’Brien, Thomas G., R. C. Simsiman, & R. K. Boutwell. (1975). Induction of the polyamine-biosynthetic enzymes in mouse epidermis by tumor-promoting agents.. Munich Personal RePEc Archive (Ludwig Maximilian University of Munich). 35(7). 1662–70. 442 indexed citations breakdown →

16.

O’Brien, Thomas G., R. C. Simsiman, & R. K. Boutwell. (1975). Induction of the polyamine-biosynthetic enzymes in mouse epidermis and their specificity for tumor promotion.. PubMed. 35(9). 2426–33. 212 indexed citations

17.

Raineri, R., R. C. Simsiman, & R. K. Boutwell. (1973). Stimulation of the phosphorylation of mouse epidermal histones by tumor-promoting agents.. PubMed. 33(1). 134–9. 67 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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