R. Bruce Wallace

10.7k citations

114 papers · 8.7k · 4 hit papers · h-index 46

Impact in

Hematology top 1%
Genetics top 1%
- Hemoglobinopathies and Related Disorders

Papers in

Molecular Biology 62
- DNA and Nucleic Acid Chemistry 21
- RNA and protein synthesis mechanisms 20
- Advanced biosensing and bioanalysis techniques 12
- RNA Research and Splicing 9
- DNA Repair Mechanisms 8
- Molecular Biology Techniques and Applications 8
Genetics 17
- Hemoglobinopathies and Related Disorders 14

Co-authors: Keiichi Itakura (13 shared papers)Dan Y. Wu (5 shared papers)Tadaaki Hirose (4 shared papers)Antonio A. Reyes (15 shared papers)Luis Ugozzoli (8 shared papers)C. Garrett Miyada (6 shared papers)Eric Kawashima (3 shared papers)B K Pal (1 shared paper)
Journals: Proceedings of the National Academy of Sciences (13 papers)Gene (5 papers)Nucleic Acids Research (5 papers)Immunogenetics (5 papers)Genomics (4 papers)
Partner nations: United States Canada United Kingdom

In The Last Decade

R. Bruce Wallace

112 papers receiving 7.9k citations

R. Bruce Wallace's Hit Papers

align trajectories log scale

Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia. 1989 · 524 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1989 Proceedings of the National Academy of Sciences
1983 Proceedings of the National Academy of Sciences
1981 Proceedings of the National Academy of Sciences
1979 Nucleic Acids Research

Peers

Countries citing papers authored by R. Bruce Wallace

Since Specialization

Citations

This map shows the geographic impact of R. Bruce Wallace's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by R. Bruce Wallace with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites R. Bruce Wallace more than expected).

Fields of papers citing papers by R. Bruce Wallace

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by R. Bruce Wallace. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by R. Bruce Wallace. The network helps show where R. Bruce Wallace may publish in the future.

Co-authors

The 25 scholars most cited alongside R. Bruce Wallace, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with R. Bruce Wallace Line = papers co-authored together R. Bruce Wallace links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 114 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Hybridization of synthetic oligodeoxyribonucleotides to Φ_X174 DNA: the effect of single base pair mismatch Nucleic Acids Research ·R. Bruce Wallace, Jacquelin B. Shaffer, Robert F. Murphy, James Bonner, Tadaaki Hirose, Keiichi Itakura Hit paper breakdown →	1979	601
2	Allele-specific enzymatic amplification of beta-globin genomic DNA for diagnosis of sickle cell anemia. Proceedings of the National Academy of Sciences ·Dan Y. Wu, Luis Ugozzoli, B K Pal, R. Bruce Wallace Hit paper breakdown →	1989	524
3	Detection of sickle cell beta S-globin allele by hybridization with synthetic oligonucleotides. Proceedings of the National Academy of Sciences ·Brenda J. Conner, Antonio A. Reyes, C Morin, Keiichi Itakura, Raymond L. Teplitz, R. Bruce Wallace Hit paper breakdown →	1983	431
4	The use of synthetic oligonucleotides as hybridization probes. II. Hybridization of oligonucleotides of mixed sequence to rabbit β-globin DNA Nucleic Acids Research ·R. Bruce Wallace, Merrie Jo Johnson, Tadaaki Hirose, Tetsuo Miyake, Eric Kawashima, Keiichi Itakura	1981	418
5	Cloning and expression in Escherichia coli of the gene for human tumour necrosis factor Nature ·Takashi Shirai, Hiroshi Yamaguchi, Hirataka Ito, C. W. Todd, R. Bruce Wallace	1985	395
6	The rat serum albumin gene: analysis of cloned sequences. Proceedings of the National Academy of Sciences ·Thomas D. Sargent, J R Wu, J M Sala-Trepat, R. Bruce Wallace, Antonio A. Reyes, James C. Bonner	1979	370
7	Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human beta 2-microglobulin. Proceedings of the National Academy of Sciences ·Sidney V. Suggs, R. Bruce Wallace, Tadaaki Hirose, Eric Kawashima, Keiichi Itakura Hit paper breakdown →	1981	360
8	A set of synthetic oligodeoxyribonucleotide primers for DNA sequencing in the plasmid vector pBR322 Gene ·R. Bruce Wallace, Merrie Jo Johnson, Sidney V. Suggs, Miyoshi Ken-ichi, Ram Bhatt, Keiichi Itakura	1981	251
9	α1-Antitrypsin deficiency detection by direct analysis of the mutation in the gene Nature ·Vincent J. Kidd, R. Bruce Wallace, Keiichi Itakura, Savio L.C. Woo	1983	229
10	SYNTHESIS AND USE OF SYNTHETIC OLIGONUCLEOTIDES Annual Review of Biochemistry ·Keiichi Itakura, John J. Rossi, R. Bruce Wallace	1984	206
11	Characteristics of older pedestrians who have difficulty crossing the street. American Journal of Public Health ·Jean Langlois, Penelope M. Keyl, Jack M. Guralnik, Dan Foley, Richard A. Marottoli, R. Bruce Wallace	1997	203
12	Anemia and Hemoglobin Levels in Older Persons: Relationship with Age, Gender, and Health Status Journal of the American Geriatrics Society ·Marcel E. Salive, Joan Cornoni‐Huntley, Jack M. Guralnik, Caroline L. Phillips, R. Bruce Wallace, Adrian M. Ostfeld, Harvey Jay Cohen	1992	196
13	[47] Oligonucleotide probes for the screening of recombinant DNA libraries Methods in enzymology on CD-ROM/Methods in enzymology ·R. Bruce Wallace, C. Garrett Miyada	1987	191
14	Oligonucleotide directed mutagenesis of the human β-globin gene: a general method for producing specific point mutations in cloned DNA Nucleic Acids Research ·R. Bruce Wallace, Monica Schöld, Merrie Jo Johnson, Piotr Dembek, Keiichi Itakura	1981	179
15	The ligation amplification reaction (LAR)—Amplification of specific DNA sequences using sequential rounds of template-dependent ligation Genomics ·Dan Y. Wu, R. Bruce Wallace	1989	177
16	Dissociation kinetics of 19 base paired oligonucleotide-DNA duplexes containing different single mismatched base pairs Nucleic Acids Research ·S. Ikuta, K. TAKAGI, R. Bruce Wallace, Keiichi Itakura	1987	177
17	Does Weight Loss from Middle Age to Old Age Explain the inverse Weight Mortality Relation in Old Age? American Journal of Epidemiology ·Katalin G. Losonczy, T. B. Harris, Joan Cornoni‐Huntley, Eleanor M. Simonsick, R. Bruce Wallace, Nancy R. Cook, A M Ostfeld, Dan G. Blazer	1995	175
18	Prenatal Diagnosis of β-Thalassemia New England Journal of Medicine ·Mario Pirastu, Yuet Wai Kan, Antonio Cao, Brenda J. Conner, Raymond L. Teplitz, R. Bruce Wallace	1983	162
19	Serum albumin in older persons: Relationship with age and health status Journal of Clinical Epidemiology ·Marcel E. Salive, Joan Cornoni‐Huntley, Caroline L. Phillips, Jack M. Guralnik, Harvey Jay Cohen, Adrian M. Ostfeld, R. Bruce Wallace	1992	151
20	Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence Age and Ageing ·Iain Lang, R. Bruce Wallace, Felicia A. Huppert, David Melzer	2007	142

About R. Bruce Wallace

R. Bruce Wallace is a scholar working on Molecular Biology, Genetics, Genetics, Hematology and Immunology, having authored 114 papers that have together received 8.7k indexed citations. Recurring topics across this work include DNA and Nucleic Acid Chemistry (21 papers), RNA and protein synthesis mechanisms (20 papers), Hemoglobinopathies and Related Disorders (14 papers), Advanced biosensing and bioanalysis techniques (12 papers), RNA Research and Splicing (9 papers), DNA Repair Mechanisms (8 papers), T-cell and B-cell Immunology (8 papers) and Molecular Biology Techniques and Applications (8 papers). The work is most often cited by research in Hematology (897 citations), Genetics (692 citations), Molecular Biology (4.6k citations), Immunology (1.0k citations) and Genetics (1.3k citations). R. Bruce Wallace has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Keiichi Itakura, Dan Y. Wu, Tadaaki Hirose, Antonio A. Reyes, Luis Ugozzoli, C. Garrett Miyada, Eric Kawashima, B K Pal, Robert F. Murphy and Sidney V. Suggs. Their work appears in journals such as Proceedings of the National Academy of Sciences, Gene, Nucleic Acids Research, Immunogenetics and Genomics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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R. Bruce Wallace

R. Bruce Wallace's Hit Papers

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About R. Bruce Wallace

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