Philip G. Penketh

1.5k total citations
60 papers, 1.3k citations indexed

About

Philip G. Penketh is a scholar working on Molecular Biology, Organic Chemistry and Cancer Research. According to data from OpenAlex, Philip G. Penketh has authored 60 papers receiving a total of 1.3k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Molecular Biology, 17 papers in Organic Chemistry and 17 papers in Cancer Research. Recurrent topics in Philip G. Penketh's work include DNA Repair Mechanisms (14 papers), Cancer, Hypoxia, and Metabolism (12 papers) and Epigenetics and DNA Methylation (12 papers). Philip G. Penketh is often cited by papers focused on DNA Repair Mechanisms (14 papers), Cancer, Hypoxia, and Metabolism (12 papers) and Epigenetics and DNA Methylation (12 papers). Philip G. Penketh collaborates with scholars based in United States, United Kingdom and Ireland. Philip G. Penketh's co-authors include Alan C. Sartorelli, Krishnamurthy Shyam, Raymond P. Baumann, Kimiko Ishiguro, Curtis L. Patton, Rui Zhu, Roger A. Klein, Regina Loomis, Sara Rockwell and Michael F. Belcourt and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Analytical Biochemistry.

In The Last Decade

Philip G. Penketh

57 papers receiving 1.2k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Philip G. Penketh United States 24 814 304 299 190 142 60 1.3k
Krishnamurthy Shyam United States 21 602 0.7× 231 0.8× 257 0.9× 139 0.7× 62 0.4× 46 937
Raghavendra Gowda United States 20 695 0.9× 115 0.4× 211 0.7× 248 1.3× 61 0.4× 37 1.2k
Kentaro Yoshimatsu Japan 22 1.1k 1.4× 673 2.2× 174 0.6× 365 1.9× 317 2.2× 40 2.1k
Michael I. Walton United Kingdom 28 1.7k 2.1× 308 1.0× 442 1.5× 719 3.8× 122 0.9× 49 2.5k
Ho H. Lee New Zealand 21 741 0.9× 397 1.3× 397 1.3× 324 1.7× 50 0.4× 40 1.6k
Rahul Palchaudhuri United States 17 1.0k 1.3× 615 2.0× 192 0.6× 501 2.6× 70 0.5× 38 1.9k
Enrica Fabbri Italy 29 1.3k 1.6× 140 0.5× 815 2.7× 191 1.0× 55 0.4× 67 1.9k
Swee Y. Sharp United Kingdom 25 2.0k 2.5× 417 1.4× 198 0.7× 750 3.9× 128 0.9× 45 2.8k
Naoyuki Kanzaki Japan 27 1.2k 1.4× 570 1.9× 195 0.7× 646 3.4× 137 1.0× 47 2.9k
Ramesh Ummanni India 25 756 0.9× 494 1.6× 231 0.8× 167 0.9× 69 0.5× 64 1.6k

Countries citing papers authored by Philip G. Penketh

Since Specialization
Citations

This map shows the geographic impact of Philip G. Penketh's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Philip G. Penketh with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Philip G. Penketh more than expected).

Fields of papers citing papers by Philip G. Penketh

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Philip G. Penketh. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Philip G. Penketh. The network helps show where Philip G. Penketh may publish in the future.

Co-authorship network of co-authors of Philip G. Penketh

This figure shows the co-authorship network connecting the top 25 collaborators of Philip G. Penketh. A scholar is included among the top collaborators of Philip G. Penketh based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Philip G. Penketh. Philip G. Penketh is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Penketh, Philip G., et al.. (2022). The Potential Development Sulfonylhydrazines for the Treatment of Alzheimer’s Disease. Biointerface Research in Applied Chemistry. 13(1). 16–16. 1 indexed citations
2.
Ishiguro, Kimiko, Yong-Lian Zhu, Z. Ping Lin, et al.. (2016). Cataloging antineoplastic agents according to their effectiveness against platinum-resistant and platinum-sensitive ovarian carcinoma cell lines.. PubMed. 2(2). 117–124. 8 indexed citations
3.
Shyam, Krishnamurthy, Philip G. Penketh, Raymond P. Baumann, et al.. (2015). Antitumor Sulfonylhydrazines: Design, Structure–Activity Relationships, Resistance Mechanisms, and Strategies for Improving Therapeutic Utility. Journal of Medicinal Chemistry. 58(9). 3639–3671. 12 indexed citations
4.
Penketh, Philip G., et al.. (2015). A simple and inexpensive method to control oxygen concentrations within physiological and neoplastic ranges. Analytical Biochemistry. 491. 1–3. 3 indexed citations
5.
Ishiguro, Kimiko, Krishnamurthy Shyam, Philip G. Penketh, et al.. (2013). Expression of O<sup>6</sup>-Methylguanine-DNA Methyltransferase Examined by Alkyl-Transfer Assays, Methylation-Specific PCR and Western Blots in Tumors and Matched Normal Tissue. Journal of Cancer Therapy. 4(4). 919–931. 12 indexed citations
6.
Penketh, Philip G., Krishnamurthy Shyam, Raymond P. Baumann, et al.. (2012). A Strategy for Selective O6‐Alkylguanine‐DNA Alkyltransferase Depletion Under Hypoxic Conditions. Chemical Biology & Drug Design. 80(2). 279–290. 11 indexed citations
7.
Baumann, Raymond P., Kimiko Ishiguro, Philip G. Penketh, et al.. (2011). KS900: A hypoxia-directed, reductively activated methylating antitumor prodrug that selectively ablates O6-alkylguanine-DNA alkyltransferase in neoplastic cells. Biochemical Pharmacology. 81(10). 1201–1210. 24 indexed citations
8.
Ishiguro, Kimiko, Yong-Lian Zhu, Krishnamurthy Shyam, et al.. (2010). Quantitative relationship between guanine O6-alkyl lesions produced by Onrigin™ and tumor resistance by O6-alkylguanine-DNA alkyltransferase. Biochemical Pharmacology. 80(9). 1317–1325. 29 indexed citations
9.
10.
Penketh, Philip G., et al.. (2004). Bioactivation and Resistance to Mitomycin C. Methods in enzymology on CD-ROM/Methods in enzymology. 382. 221–233. 38 indexed citations
11.
Penketh, Philip G., William F. Hodnick, Michael F. Belcourt, et al.. (2001). Inhibition of DNA Cross-linking by Mitomycin C by Peroxidase-mediated Oxidation of Mitomycin C Hydroquinone. Journal of Biological Chemistry. 276(37). 34445–34452. 22 indexed citations
12.
Penketh, Philip G., Krishnamurthy Shyam, & Alan C. Sartorelli. (2000). Comparison of DNA lesions produced by tumor-inhibitory 1,2-bis(sulfonyl)hydrazines and chloroethylnitrosoureas. Biochemical Pharmacology. 59(3). 283–291. 64 indexed citations
13.
Belcourt, Michael F., Philip G. Penketh, William F. Hodnick, et al.. (1999). Mitomycin resistance in mammalian cells expressing the bacterial mitomycin C resistance protein MCRA. Proceedings of the National Academy of Sciences. 96(18). 10489–10494. 23 indexed citations
14.
Penketh, Philip G., et al.. (1997). Fluorometric Assay for the Determination of DNA–DNA Cross-Links Utilizing Hoechst 33258 at Neutral pH Values. Analytical Biochemistry. 252(1). 210–213. 22 indexed citations
15.
Penketh, Philip G., et al.. (1996). Spectrophotometric Assay for Processes Involving Changes in Hydrogen Ion Concentration in Aqueous Solution. Analytical Biochemistry. 238(1). 46–49. 10 indexed citations
16.
Liu, Mao‐Chin, Tai‐Shun Lin, Philip G. Penketh, & Alan C. Sartorelli. (1995). Synthesis and Antitumor Activity of 4- and 5-Substituted Derivatives of Isoquinoline-1-carboxaldehyde Thiosemicarbazone. Journal of Medicinal Chemistry. 38(21). 4234–4243. 41 indexed citations
17.
Penketh, Philip G., Krishnamurthy Shyam, & Alan C. Sartorelli. (1994). Studies on the Mechanism of Decomposition and Structural Factors Affecting the Aqueous Stability of 1,2-Bis(sulfonyl)-1-alkylhydrazines. Journal of Medicinal Chemistry. 37(18). 2912–2917. 26 indexed citations
18.
Penketh, Philip G., et al.. (1993). Synthesis and evaluation of 1-acyl-1,2-bis(methylsulfonyl)-2-(2-chloroethyl)hydrazines as antineoplastic agents. Journal of Medicinal Chemistry. 36(23). 3496–3502. 23 indexed citations
19.
Penketh, Philip G., et al.. (1991). Enhancement of the trypanocidal activity of methyltriazenes in an animal model by the addition of an amidino group. Acta Tropica. 49(1). 69–72. 3 indexed citations
20.
Penketh, Philip G., W. Poindexter Kennedy, Curtis L. Patton, & Alan C. Sartorelli. (1987). Trypanosomatid hydrogen peroxidase metabolism. FEBS Letters. 221(2). 427–431. 47 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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