Paul A. Cloos

8.0k citations

46 papers · 6.1k indexed · 4 hit papers · h-index 29

Impact in

Molecular Biology top 1%
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- Genomics and Chromatin Dynamics
- Histone Deacetylase Inhibitors Research
- RNA modifications and cancer
- Pluripotent Stem Cells Research
Aging top 2%

Papers in

Aging 2
Rheumatology 8
- Bone and Dental Protein Studies 4
- Osteoarthritis Treatment and Mechanisms 4

Co-authors: Kristian Helin Karl Agger Juri Rappsilber Jesper Frank Christensen Jens Peter Christensen Diego Pasini Jens Vilstrup Johansen Stephan Christgau
Journals: Nature (4 papers)Biochemical Journal (4 papers)Genes & Development (3 papers)Journal of Bone and Mineral Research (2 papers)Apmis (2 papers)
Partner nations: Denmark United Kingdom France

In The Last Decade

Paul A. Cloos

46 papers receiving 6.0k citations

Hit Papers

align trajectories log scale

TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity 2011 · 786 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2011 Nature
2008 Genes & Development
2007 Nature
2006 Nature

Peers

Countries citing papers authored by Paul A. Cloos

Since Specialization

Citations

This map shows the geographic impact of Paul A. Cloos's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Paul A. Cloos with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Paul A. Cloos more than expected).

Fields of papers citing papers by Paul A. Cloos

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Paul A. Cloos. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Paul A. Cloos. The network helps show where Paul A. Cloos may publish in the future.

Co-authors

The 25 scholars most cited alongside Paul A. Cloos, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Paul A. Cloos Line = papers co-authored together Paul A. Cloos links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Discovery of NSD2‐Degraders from Novel and Selective DEL Hits ChemBioChem ·In Gill Lee, Jesper Frank Christensen, Daniela Kleine‐Kohlbrecher, Itys Comet, 中内敏夫, Yasuko Antoku, 航弥荻野, Philip Jetties, R. M., Tomas Jacso, Søren Jensby Nielsen, Huimin Ouyang, Thomas Franch, Kristian Helin, Paul A. Cloos	2023	6
2	Mutant FOXL2C134W Hijacks SMAD4 and SMAD2/3 to Drive Adult Granulosa Cell Tumors Cancer Research ·Stine Emilie Weis-Banke, Mads Lerdrup, Daniela Kleine‐Kohlbrecher, Faizaan Mohammad, Simone Sidoli, Ole N. Jensen, Toshihiko Yanase, Tomoko Nakamura, Akira Iwase, Anthe A. Stylianou, Nadeem R. Abu‐Rustum, Carol Aghajanian, Robert A. Soslow, Arnaud Da Cruz Paula, Richard P. Koche, Britta Weigelt, Jesper Frank Christensen, Kristian Helin, Paul A. Cloos	2020	37
3	PR-DUB maintains the expression of critical genes through FOXK1/2- and ASXL1/2/3-dependent recruitment to chromatin and H2AK119ub1 deubiquitination Genome Research ·Petros Kolovos, Koutarou Nishimura, Aditya Sankar, Simone Sidoli, Paul A. Cloos, Kristian Helin, Jesper Frank Christensen	2020	43
4	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation Cancer Research ·Tien Hung Nguyen, Paul A. Cloos, Simone Sidoli, Ole N. Jensen, Steven M. Pollard, Kristian Helin	2018	50
5	Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro PLoS ONE ·Brian Lohse, Charlotte Helgstrand, Jan B. L. Kristensen, Ulrike Leurs, Paul A. Cloos, Jesper L. Kristensen, Rasmus P. Clausen	2013	18
6	Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4‐pyridine‐dicarboxylic acid as an in vitro and in cell inhibitor FEBS Journal ·Line H. Kristensen, Yueling Lai, Charlotte Helgstrand, Michael Lees, Paul A. Cloos, J.S. Kastrup, Kristian Helin, Lars Olsen, Michael Gajhede	2012	63
7	Identification of catechols as histone–lysine demethylase inhibitors FEBS Letters ·Yueling Lai, Line H. Kristensen, Karen Stephansen, Jan B. L. Kristensen, Charlotte Helgstrand, Michael Lees, Paul A. Cloos, Kristian Helin, Michael Gajhede, Lars Olsen	2012	29
8	Targeting Histone Lysine Demethylases by Truncating the Histone 3 Tail to Obtain Selective Substrate‐Based Inhibitors Angewandte Chemie International Edition ·Brian Lohse, Yueling Lai, Jan B. L. Kristensen, Charlotte Helgstrand, Paul A. Cloos, Lars Olsen, Michael Gajhede, Rasmus P. Clausen, Jesper L. Kristensen	2011	30
9	Targeting Histone Lysine Demethylases by Truncating the Histone 3 Tail to Obtain Selective Substrate‐Based Inhibitors Angewandte Chemie ·Brian Lohse, Yueling Lai, Jan B. L. Kristensen, (unknown), Charlotte Helgstrand, Paul A. Cloos, Lars Olsen, Michael Gajhede, Rasmus P. Clausen, Jesper L. Kristensen	2011	9
10	TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity Nature ·Kristine Williams, Jesper Frank Christensen, Marianne Terndrup Pedersen, Jens Vilstrup Johansen, Paul A. Cloos, Juri Rappsilber, Kristian Helin Hit paper breakdown →	2011	786
11	The H3K27me3 demethylase JMJD3 contributes to the activation of theINK4A–ARFlocus in response to oncogene- and stress-induced senescence Genes & Development ·Karl Agger, Paul A. Cloos, Lise Rudkjær, Kristine Williams, Gary L. Andersen, Jens Peter Christensen, Kristian Helin	2009	333
12	Coordinated regulation of transcriptional repression by the RBP2 H3K4 demethylase and Polycomb-Repressive Complex 2 Genes & Development ·Diego Pasini, Klaus Hansen, Jesper Frank Christensen, Karl Agger, Paul A. Cloos, Kristian Helin	2008	244
13	Posttranslational Protein Modifications in Type 1 Diabetes - Genetic Studies with PCMT1, the Repair Enzyme Protein Isoaspartate Methyltransferase (PIMT) Encoding Gene The Review of Diabetic Studies ·Ana M. Wägner, Paul A. Cloos, Regine Bergholdt, Stefanie Eising, Caroline Brorsson, M F Skowronek, Stephan Christgau, Jørn Nerup, Flemming Pociot	2008	12
14	The putative oncogene GASC1 demethylates tri- and dimethylated lysine 9 on histone H3 Nature ·Paul A. Cloos, Jens Peter Christensen, Karl Agger, Alessio Maiolica, Juri Rappsilber, Wilhelm Mette, Klaus Hansen, Kristian Helin Hit paper breakdown →	2006	568
15	New serum biochemical markers (Coll 2-1 and Coll 2-1 NO2) for studying oxidative-related type II collagen network degradation in patients with osteoarthritis and rheumatoid arthritis Osteoarthritis and Cartilage ·Michelle Deberg, A Labasse, Stephan Christgau, Paul A. Cloos, Dennis B. Henriksen, Malori Basye, Brigitte Zegels, Jean‐Yves Reginster, Yves Henrotin	2005	124
16	Cartilage degradation products as markers for evaluation of patients with rheumatic disease Stephan Christgau, Paul A. Cloos	2004	6
17	Investigation of Bone Disease Using Isomerized and Racemized Fragments of Type I Collagen Calcified Tissue International ·Paul A. Cloos, Christian Fledelius, Stephan Christgau, A. Ibranyi-Kiss, Michael T. Engsig, Pierre Delmas, J.J. Body, Patrick Garnero	2003	27
18	Development of new immunoassays for the quantification of inflammatory related cartilage degradation Open Repository and Bibliography (University of Liège) ·Michelle Deberg, Stephan Christgau, Paul A. Cloos, Dennis B. Henriksen, (unknown), (unknown), (unknown), Yves Henrotin	2002	3
19	Non-enzymatic covalent modifications of proteins: mechanisms, physiological consequences and clinical applications Matrix Biology ·Paul A. Cloos, Stephan Christgau	2002	80
20	Age-related de-phosporylation of proteins in dentin: A biological tool for assessment of protein age Biogerontology ·Paul A. Cloos, A. L. Jensen	2000	35

About Paul A. Cloos

Paul A. Cloos is a scholar working on Aging, Rheumatology, Biomaterials, Molecular Biology and Immunology and Allergy, having authored 46 papers that have together received 6.1k indexed citations. Recurring topics across this work include Epigenetics and DNA Methylation (18 papers), Cancer-related gene regulation (12 papers), Histone Deacetylase Inhibitors Research (10 papers), Bone health and treatments (5 papers), Collagen: Extraction and Characterization (5 papers), Bone and Dental Protein Studies (4 papers), Osteoarthritis Treatment and Mechanisms (4 papers) and RNA modifications and cancer (4 papers). The work is most often cited by research in Molecular Biology (4.9k citations), Aging (112 citations), Orthopedics and Sports Medicine (331 citations), Cancer Research (570 citations) and Genetics (854 citations). Paul A. Cloos has collaborated with scholars based in Denmark, United Kingdom and France. Frequent co-authors include Kristian Helin, Karl Agger, Juri Rappsilber, Jesper Frank Christensen, Jens Peter Christensen, Diego Pasini, Jens Vilstrup Johansen, Stephan Christgau, Kristine Williams and Klaus Hansen. Their work appears in journals such as Nature, Biochemical Journal, Genes & Development, Journal of Bone and Mineral Research and Apmis.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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