Guo Chen

17.3k total citations · 9 hit papers
284 papers, 8.0k citations indexed

About

Guo Chen is a scholar working on Molecular Biology, Cancer Research and Immunology. According to data from OpenAlex, Guo Chen has authored 284 papers receiving a total of 8.0k indexed citations (citations by other indexed papers that have themselves been cited), including 145 papers in Molecular Biology, 55 papers in Cancer Research and 41 papers in Immunology. Recurrent topics in Guo Chen's work include Cancer-related molecular mechanisms research (19 papers), RNA modifications and cancer (18 papers) and Autophagy in Disease and Therapy (16 papers). Guo Chen is often cited by papers focused on Cancer-related molecular mechanisms research (19 papers), RNA modifications and cancer (18 papers) and Autophagy in Disease and Therapy (16 papers). Guo Chen collaborates with scholars based in China, United States and France. Guo Chen's co-authors include Oliver Kepp, Quan Chen, Yushan Zhu, Guido Kroemer, Xingming Deng, Lei Liu, Kaili Ma, Wenhui Li, Hans Frauenfelder and Jan Swenson and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Nucleic Acids Research and Advanced Materials.

In The Last Decade

Guo Chen

260 papers receiving 7.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A unified model of protein dynamics

2009 601 citations Guo Chen et al. profile →
A Regulatory Signaling Loop Comprising the PGAM5 Phosphatase and CK2 Controls Receptor-Mediated Mitophagy

2014 463 citations Guo Chen, Lei Liu et al. profile →
Mitophagy, Mitochondrial Homeostasis, and Cell Fate

2020 425 citations Guo Chen, Quan Chen et al. profile →
Tau reduction prevents neuronal loss and reverses pathological tau deposition and seeding in mice with tauopathy

2017 362 citations Guo Chen et al. profile →
Mitophagy: An Emerging Role in Aging and Age-Associated Diseases

2020 268 citations Guo Chen et al. profile →
Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis

2022 185 citations Guo Chen, Yanjun Li et al. profile →
Crosstalk between mitochondrial biogenesis and mitophagy to maintain mitochondrial homeostasis

2023 136 citations Lei Liu, Yanjun Li et al. Journal of Biomedical Science profile →
MVBench: A Comprehensive Multi-modal Video Understanding Benchmark

2024 59 citations Guo Chen et al. profile →
NGR‐Modified CAF‐Derived exos Targeting Tumor Vasculature to Induce Ferroptosis and Overcome Chemoresistance in Osteosarcoma

2025 22 citations Guo Chen et al. profile →

Peers

Countries citing papers authored by Guo Chen

Since Specialization

Citations

This map shows the geographic impact of Guo Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Guo Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Guo Chen more than expected).

Fields of papers citing papers by Guo Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Guo Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Guo Chen. The network helps show where Guo Chen may publish in the future.

Co-authorship network of co-authors of Guo Chen

This figure shows the co-authorship network connecting the top 25 collaborators of Guo Chen. A scholar is included among the top collaborators of Guo Chen based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Guo Chen. Guo Chen is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	A metal-drug self-delivery nanomedicine alleviates tumor immunosuppression to potentiate synergistic chemo/chemodynamic therapy against hepatocellular carcinoma 2024 ·Fundamental Research ·Guo Chen, Rui Dou, (unknown), Jiayu Zhang, Xiaomeng Cai, (unknown), (unknown), Margaret Liu, Jun Chen, Hanqing Chen	0
2	Targeting the mTOR Pathway in Hepatocellular Carcinoma: The Therapeutic Potential of Natural Products 2024 ·Journal of Inflammation Research ·Guo Chen, Ya Zhang, (unknown), Hao Luo, Hongzhi Guan, (unknown)	2
3	IGF2BP3-EGFR-AKT axis promotes breast cancer MDA-MB-231 cell growth 2023 ·Biochimica et Biophysica Acta (BBA) - Molecular Cell Research ·(unknown), Cong Han, Qian Li, Fang Li, Jinyuan Zhang, Qiuyu Jiang, Fei Zhao, Guo Chen, Jinfeng Chen, Ting Jiang, Xiaofei Wang, Yanke Chen, Chen Huang	5
4	Low-dose ketamine inhibits neuronal apoptosis and neuroinflammation in PC12 cells via α7nAChR mediated TLR4/MAPK/NF-κB signaling pathway 2023 ·International Immunopharmacology ·Jinghua Zhao, Ruxin Zhang, Wei Wang, Sheng Jiang, (unknown), Guo Chen, (unknown), Huan Zeng, Houhui Song	14
5	Performance of microenvironment-induced lipase immobilization on diversify surface of magnetic particle 2023 ·Colloids and Surfaces B Biointerfaces ·(unknown), Liang Wang, Guo Chen, Jun Zhao	9
6	Crosstalk between mitochondrial biogenesis and mitophagy to maintain mitochondrial homeostasis breakdown → 2023 ·Journal of Biomedical Science ·Lei Liu, Yanjun Li, Guo Chen, Quan Chen	136
7	A GM-CSF and DOX co-delivery nanoplatform modulates macrophage polarization to promote tumor suppression 2023 ·SHILAP Revista de lepidopterología ·Miao Wang, (unknown), (unknown), Xiaomeng Cai, Rui Dou, Guo Chen, Yi Hu, Jun Chen	6
8	BasicTAD: An astounding RGB-Only baseline for temporal action detection 2023 ·Computer Vision and Image Understanding ·Min Yang, Guo Chen, (unknown), Tong Lü, Limin Wang	27
9	Acupuncture for carpal tunnel syndrome: A systematic review and meta-analysis of randomized controlled trials 2023 ·Frontiers in Neuroscience ·(unknown), Xiaoyan Li, Ping Yuan, Guo Chen, Jianfeng Li, Jun Deng, Fan Wu, (unknown), (unknown), Rongjiang Jin	8
10	Chanling Gao suppresses colorectal cancer via PI3K /Akt/ mTOR pathway modulation and enhances quality of survival 2023 ·Environmental Toxicology ·Guo Chen, Tingting Tian, (unknown), Chun‐Shui Pan, Kai Sun, (unknown), Bing Yang, (unknown), (unknown), (unknown)	5
11	Salmonella flagella confer anti-tumor immunological effect via activating Flagellin/TLR5 signalling within tumor microenvironment 2021 ·Acta Pharmaceutica Sinica B ·Jianxiang Chen, Yiting Qiao, Guo Chen, Cunjie Chang, Heng Dong, Bo Tang, Xiawei Cheng, Xiufeng Liu, Zichun Hua	49
12	Bergenin Exerts Hepatoprotective Effects by Inhibiting the Release of Inflammatory Factors, Apoptosis and Autophagy via the PPAR-γ Pathway 2020 ·SHILAP Revista de lepidopterología ·Sheng Xiang, Kewei Chen, Liang Xu, Timothy C. Wang, Guo Chen	1
13	Cellular magnetic resonance imaging: in vivo tracking of gastric cancer cells and detecting of lymph node metastases using microparticles of iron oxide in mice 2019 ·SHILAP Revista de lepidopterología ·Jian Chen, (unknown), Ren Cai, Xin Wu, (unknown), Jing Zhao, Haitao Li, Guo Chen	1
14	Upregulation of long non-coding RNA FOXP4-AS1 and its regulatory network in hepatocellular carcinoma 2019 ·SHILAP Revista de lepidopterología ·(unknown), Tao Bai, Guo Chen, Jiajun Liu, Ming Chen, (unknown), Tao Luo, Jin Chen, Li L, Chen Zhang, Hung‐Yuan Li	1
15	Aberrant FGFR Tyrosine Kinase Signaling Enhances the Warburg Effect by Reprogramming LDH Isoform Expression and Activity in Prostate Cancer 2018 ·Cancer Research ·Junchen Liu, Guo Chen, Zezhen Liu, Shaoyou Liu, Zhiduan Cai, Pan You, Yuepeng Ke, Li Lai, Yun Huang, Hongchang Gao, Liangcai Zhao, Hélène Pelicano, Peng Huang, Wallace L. McKeehan, Chin‐Lee Wu, Cong Wang, Weide Zhong, Fen Wang	88
16	DJ-1 promotes survival of human colon cancer cells under hypoxia by modulating HIF-1α expression through the PI3K-AKT pathway 2018 ·SHILAP Revista de lepidopterología ·Huiyuan Zheng, C. Zhou, Xiao Lu, Yongsheng Liu, (unknown), Guo Chen, Wenjia Chen, Shudong Wang, (unknown)	2
17	Honokiol Radiosensitizes Squamous Cell Carcinoma of the Head and Neck by Downregulation of Survivin 2017 ·Clinical Cancer Research ·Xu Wang, Jonathan J. Beitler, Wen‐Chin Huang, Guo Chen, Guoqing Qian, Kelly R. Magliocca, Mihir R. Patel, Amy Y. Chen, Jun Zhang, Sreenivas Nannapaneni, Sungjin Kim, Zhengjia Chen, Xingming Deng, Nabil F. Saba, Zhuo Georgia Chen, Jack L. Arbiser, Dong M. Shin	23
18	Inhibition of mTORC1/2 Overcomes Resistance to MAPK Pathway Inhibitors Mediated by PGC1α and Oxidative Phosphorylation in Melanoma 2014 ·Cancer Research ·Y.N. Vashisht Gopal, Helen Rizos, Guo Chen, Wanleng Deng, Dennie T. Frederick, Zachary A. Cooper, Richard A. Scolyer, Gulietta M. Pupo, Kakajan Komurov, Vasudha Sehgal, Jiexin Zhang, Lalit R. Patel, Cristiano Gonçalves Pereira, Bradley M. Broom, Gordon B. Mills, Prahlad T. Ram, Paul D. Smith, Jennifer A. Wargo, Georgina V. Long, Michael A. Davies	148
19	Molecular Profiling of Patient-Matched Brain and Extracranial Melanoma Metastases Implicates the PI3K Pathway as a Therapeutic Target 2014 ·Clinical Cancer Research ·Guo Chen, Nitin Chakravarti, Kimberly Aardalen, Alexander J. Lazar, Michael T. Tetzlaff, Bradley Wubbenhorst, Sang-Bae Kim, Scott Kopetz, Alicia A. Ledoux, Y.N. Vashisht Gopal, Cristiano Gonçalves Pereira, Wanleng Deng, Ju‐Seog Lee, Katherine L. Nathanson, Kenneth Aldape, Víctor G. Prieto, Darrin D. Stuart, Michael A. Davies	120
20	Complete Loss of PTEN Protein Expression Correlates with Shorter Time to Brain Metastasis and Survival in Stage IIIB/C Melanoma Patients with BRAF V600 Mutations 2014 ·Clinical Cancer Research ·Amanda D. Bucheit, Guo Chen, Alan Siroy, Michael T. Tetzlaff, Russell R. Broaddus, Denái R. Milton, Patricia S. Fox, Roland L. Bassett, Patrick Hwu, Jeffrey E. Gershenwald, Alexander J. Lazar, Michael A. Davies	109

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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