Ole Helm

1.0k citations

21 papers · 804 indexed · h-index 14

Impact in

Immunology top 10%
- Immune cells in cancer
- Phagocytosis and Immune Regulation
Oncology top 10%
- Pancreatic and Hepatic Oncology Research
- Cancer Cells and Metastasis
- Cancer Immunotherapy and Biomarkers

Papers in ⓘ

Oncology 13
- Pancreatic and Hepatic Oncology Research 12
- Cancer Cells and Metastasis 2
Molecular Biology 10
- Genomics, phytochemicals, and oxidative stress 4
- Epigenetics and DNA Methylation 3

Co-authors: Susanne Sebens (21 shared papers)H. Schäfer (11 shared papers)Christoph Röcken (11 shared papers)Janka Held‐Feindt (3 shared papers)Hendrik Ungefroren (5 shared papers)Bence Sipos (7 shared papers)Dieter Kabelitz (2 shared papers)Evelin Grage‐Griebenow (2 shared papers)
Journals: Oncotarget (3 papers)OncoImmunology (3 papers)PLoS ONE (3 papers)Cancers (2 papers)Oncogene (2 papers)
Partner nations: Germany United States Taiwan

In The Last Decade

Ole Helm

21 papers receiving 799 citations

Peers

Countries citing papers authored by Ole Helm

Since Specialization

Citations

This map shows the geographic impact of Ole Helm's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Ole Helm with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Ole Helm more than expected).

Fields of papers citing papers by Ole Helm

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Ole Helm. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Ole Helm. The network helps show where Ole Helm may publish in the future.

Co-authors

The 25 scholars most cited alongside Ole Helm, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Ole Helm Line = papers co-authored together Ole Helm links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 21 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Tumor‐associated macrophages exhibit pro‐ and anti‐inflammatory properties by which they impact on pancreatic tumorigenesis International Journal of Cancer ·Ole Helm, Janka Held‐Feindt, Evelin Grage‐Griebenow, Norbert Reiling, Hendrik Ungefroren, Ilka Vogel, Uwe Krüger, Thomas Becker, Michael Ebsen, Christoph Röcken, Dieter Kabelitz, H. Schäfer, Susanne Sebens	2014	214
2	Diabetes as risk factor for pancreatic cancer: Hyperglycemia promotes epithelial-mesenchymal-transition and stem cell properties in pancreatic ductal epithelial cells Cancer Letters ·Sascha Rahn, Vivien Zimmermann, Fabrice Viol, Hendrike Knaack, Kerstin Stemmer, Lena Peters, Lennart Lenk, Hendrik Ungefroren, Dieter Saur, H. Schäfer, Ole Helm, Susanne Sebens	2017	90
3	Comparative Characterization of Stroma Cells and Ductal Epithelium in Chronic Pancreatitis and Pancreatic Ductal Adenocarcinoma PLoS ONE ·Ole Helm, Ruben Mennrich, Domantas Petrick, Lisa Goebel, Sandra Freitag‐Wolf, Christian Röder, Holger Kalthoff, Christoph Röcken, Bence Sipos, Dieter Kabelitz, H. Schäfer, Hans‐Heinrich Oberg, Daniela Wesch, Susanne Sebens	2014	61
4	Chemokine expression profile of freshly isolated human glioblastoma-associated macrophages/microglia Oncology Reports ·Kirsten Hattermann, Susanne Sebens, Ole Helm, Anne Dorothée Schmitt, Rolf Mentlein, H. Maximilian Mehdorn, Janka Held‐Feindt	2014	56
5	The Crosstalk between Nrf2 and TGF-β1 in the Epithelial-Mesenchymal Transition of Pancreatic Duct Epithelial Cells PLoS ONE ·Sarah Arfmann-Knübel, Birte Struck, Geeske Genrich, Ole Helm, Bence Sipos, Susanne Sebens, H. Schäfer	2015	52
6	Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling Oncotarget ·Hendrik Ungefroren, Susanne Sebens, Klaudia Giehl, Ole Helm, Stephanie Groth, Fred Fändrich, Christoph Röcken, Bence Sipos, Hendrik Lehnert, Frank Gieseler	2013	44
7	Nuclear factor E2-related factor-2 has a differential impact on MCT1 and MCT4 lactate carrier expression in colonic epithelial cells: a condition favoring metabolic symbiosis between colorectal cancer and stromal cells Oncogene ·K. Diehl, L-A Dinges, Ole Helm, N. Ammar, Dorothea Plundrich, Alexander Arlt, Christoph Röcken, Susanne Sebens, H. Schäfer	2017	42
8	CD4⁺T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells–novel implications of CD4⁺T cells in pancreatic cancer development OncoImmunology ·Lisa Goebel, Evelin Grage‐Griebenow, Artur Gorys, Ole Helm, Geeske Genrich, Lennart Lenk, Daniela Wesch, Hendrik Ungefroren, Sandra Freitag‐Wolf, Bence Sipos, Christoph Röcken, H. Schäfer, Susanne Sebens	2015	41
9	The hepatic microenvironment essentially determines tumor cell dormancy and metastatic outgrowth of pancreatic ductal adenocarcinoma OncoImmunology ·Lennart Lenk, Maren Pein, Olga Will, Beatriz Aguilar Gomez, Fabrice Viol, Charlotte A. E. Hauser, Jan-Hendrik Egberts, Jan-Paul Gundlach, Ole Helm, Sanjay Tiwari, Ralf Weiskirchen, Stefan Rose‐John, Christoph Röcken, Wolfgang Mikulits, Patrick Wenzel, Günter Schneider, Dieter Saur, H. Schäfer, Susanne Sebens	2017	35
10	M1 and M2: there is no “good” and “bad”—How macrophages promote malignancy-associated features in tumorigenesis OncoImmunology ·Ole Helm, Janka Held‐Feindt, H. Schäfer, Susanne Sebens	2014	33
11	Chitosan nanoparticles as antigen vehicles to induce effective tumor specific T cell responses PLoS ONE ·Frederik Walter, Elsa Winter, Sascha Rahn, Judith Heidland, Saskia Meier, Anna-Maria Struzek, Marcus Lettau, Lisa-Marie Philipp, Silje Beckinger, Lilli Otto, Julia Luisa Möller, Ole Helm, Daniela Wesch, Regina Scherließ, Susanne Sebens	2020	25
12	POLE Score: a comprehensive profiling of programmed death 1 ligand 1 expression in pancreatic ductal adenocarcinoma Oncotarget ·Sascha Rahn, Sandra Krüger, Ruben Mennrich, Lisa Goebel, Daniela Wesch, Hans‐Heinrich Oberg, Ilka Vogel, Michael Ebsen, Christoph Röcken, Ole Helm, Susanne Sebens	2019	18
13	The anti-oxidative transcription factor Nuclear factor E2 related factor-2 (Nrf2) counteracts TGF-β1 mediated growth inhibition of pancreatic ductal epithelial cells -Nrf2 as determinant of pro-tumorigenic functions of TGF-β1 BMC Cancer ·Geeske Genrich, Marcus Kruppa, Lennart Lenk, Ole Helm, Anna Broich, Sandra Freitag‐Wolf, Christoph Röcken, Bence Sipos, H. Schäfer, Susanne Sebens	2016	16
14	The antioxidant transcription factor Nrf2 modulates the stress response and phenotype of malignant as well as premalignant pancreatic ductal epithelial cells by inducing expression of the ATF3 splicing variant ΔZip2 Oncogene ·My-Lan Kha, Lisa Hesse, Florian Deisinger, Bence Sipos, Christoph Röcken, Alexander Arlt, Susanne Sebens, Ole Helm, H. Schäfer	2018	16
15	The Hepatic Microenvironment and TRAIL-R2 Impact Outgrowth of Liver Metastases in Pancreatic Cancer after Surgical Resection Cancers ·Lauritz Miarka, Charlotte A. E. Hauser, Ole Helm, Dörthe Holdhof, Silje Beckinger, Jan-Hendrik Egberts, Jan-Paul Gundlach, Lennart Lenk, Sascha Rahn, Wolfgang Mikulits, Anna Trauzold, Susanne Sebens	2019	13
16	Cancer-associated mutations in the canonical cleavage site do not influence CD99 shedding by the metalloprotease meprin β but alter cell migration in vitro Oncotarget ·Tillmann Bedau, Neele Schumacher, Florian Peters, Johannes Prox, Philipp Arnold, Tomas Koudelka, Ole Helm, Frederike Schmidt, Björn Rabe, Marlene Jentzsch, Philip Rosenstiel, Susanne Sebens, Andreas Tholey, Stefan Rose‐John, Christoph Becker‐Pauly	2017	13
17	Negative control of TRAIL-R1 signaling by transforming growth factor β1 in pancreatic tumor cells involves Smad-dependent down regulation of TRAIL-R1 Cellular Signalling ·David I. Radke, Hendrik Ungefroren, Ole Helm, Susann Voigt, Gökhan Alp, Hendrik Braun, Sebastian Hübner, Janine Dilchert, Susanne Sebens, Dieter Adam, Holger Kalthoff, Anna Trauzold	2016	11
18	The cancer-associated meprin β variant G32R provides an additional activation site and promotes cancer cell invasion Journal of Cell Science ·Henning Schäffler, Wenjia Li, Ole Helm, Sandra Krüger, Christine Böger, Florian Peters, Christoph Röcken, Susanne Sebens, Ralph Lucius, Christoph Becker‐Pauly, Philipp Arnold	2019	11
19	Plant-derived saccharides and their inhibitory potential on metastasis associated cellular processes of pancreatic ductal adenocarcinoma cells Carbohydrate Research ·Meike Schöll-Naderer, Ole Helm, Josephine Spencker, Lukáš Pfeifer, Tilo Rätsch, Susanne Sebens, Birgit Classen	2019	5
20	Characterization of the Cancer-Associated Meprin Βeta Variants G45R and G89R Frontiers in Molecular Biosciences ·Antonin L. Gellrich, Franka Scharfenberg, Florian Peters, Martin Sammel, Ole Helm, Fred Armbrust, Frederike Schmidt, Juliane Lokau, Christoph Garbers, Susanne Sebens, Philipp Arnold, Christoph Becker‐Pauly	2021	4

About Ole Helm

Ole Helm is a scholar working on Oncology, Molecular Biology, Immunology, Surgery and Immunology and Allergy, having authored 21 papers that have together received 804 indexed citations. Recurring topics across this work include Pancreatic and Hepatic Oncology Research (12 papers), Phagocytosis and Immune Regulation (4 papers), Pancreatitis Pathology and Treatment (4 papers), Genomics, phytochemicals, and oxidative stress (4 papers), Immune cells in cancer (4 papers), Cell Adhesion Molecules Research (3 papers), Epigenetics and DNA Methylation (3 papers) and Cancer Cells and Metastasis (2 papers). The work is most often cited by research in Immunology (334 citations), Oncology (409 citations), Cancer Research (174 citations), Molecular Biology (360 citations) and Neurology (36 citations). Ole Helm has collaborated with scholars based in Germany, United States and Taiwan. Frequent co-authors include Susanne Sebens, H. Schäfer, Christoph Röcken, Janka Held‐Feindt, Hendrik Ungefroren, Bence Sipos, Dieter Kabelitz, Evelin Grage‐Griebenow, Michael Ebsen and Ilka Vogel. Their work appears in journals such as Oncotarget, OncoImmunology, PLoS ONE, Cancers and Oncogene.

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