Nicholas Gekakis

4.5k total citations · 2 hit papers
21 papers, 3.7k citations indexed

About

Nicholas Gekakis is a scholar working on Molecular Biology, Surgery and Endocrine and Autonomic Systems. According to data from OpenAlex, Nicholas Gekakis has authored 21 papers receiving a total of 3.7k indexed citations (citations by other indexed papers that have themselves been cited), including 12 papers in Molecular Biology, 9 papers in Surgery and 6 papers in Endocrine and Autonomic Systems. Recurrent topics in Nicholas Gekakis's work include Pancreatic function and diabetes (8 papers), Circadian rhythm and melatonin (5 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). Nicholas Gekakis is often cited by papers focused on Pancreatic function and diabetes (8 papers), Circadian rhythm and melatonin (5 papers) and Endoplasmic Reticulum Stress and Disease (5 papers). Nicholas Gekakis collaborates with scholars based in United States, Australia and Canada. Nicholas Gekakis's co-authors include Charles J. Weitz, David Staknis, Joseph S. Takahashi, David P. King, Fred C. Davis, Lisa D. Wilsbacher, Karen Wager‐Smith, Thomas K. Darlington, Thomas Steeves and M. Fernanda Ceriani and has published in prestigious journals such as Science, Journal of Biological Chemistry and Neuron.

In The Last Decade

Nicholas Gekakis

20 papers receiving 3.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Role of the CLOCK Protein in the Mammalian Circadian Mechanism

1998 1.6k citations Nicholas Gekakis, David Staknis et al. Science profile →
Closing the Circadian Loop: CLOCK-Induced Transcription of Its Own Inhibitors per and tim

1998 688 citations Thomas K. Darlington, Karen Wager‐Smith et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Nicholas Gekakis United States	17	2.7k	1.3k	902	880	852	21	3.7k
Vivek Kumar United States	22	2.2k 0.8×	955 0.8×	1.0k 1.2×	1.4k 1.6×	579 0.7×	58	4.0k
Eric Erquan Zhang China	29	2.5k 1.0×	914 0.7×	1.2k 1.3×	1.5k 1.7×	712 0.8×	67	4.5k
Brooke H. Miller United States	16	2.6k 1.0×	613 0.5×	1.4k 1.6×	1.2k 1.3×	817 1.0×	19	4.3k
Tsuyoshi Hirota Japan	31	2.9k 1.1×	1.2k 1.0×	1.2k 1.3×	864 1.0×	856 1.0×	63	4.0k
Lino Sáez United States	26	2.5k 0.9×	1.7k 1.3×	455 0.5×	940 1.1×	1.2k 1.4×	36	3.5k
Aurélio Balsalobre Canada	18	3.4k 1.3×	944 0.7×	1.6k 1.8×	1000 1.1×	844 1.0×	26	4.7k
Filippo Tamanini Netherlands	25	1.5k 0.6×	811 0.6×	545 0.6×	1.2k 1.4×	532 0.6×	38	2.9k
Jürgen A. Ripperger Switzerland	26	2.7k 1.0×	739 0.6×	1.2k 1.4×	706 0.8×	616 0.7×	50	3.6k
Sriram Sathyanarayanan United States	17	2.6k 1.0×	1.3k 1.0×	894 1.0×	803 0.9×	836 1.0×	32	3.6k
Emi Nagoshi Switzerland	22	1.6k 0.6×	628 0.5×	588 0.7×	908 1.0×	661 0.8×	46	2.7k

Countries citing papers authored by Nicholas Gekakis

Since Specialization

Citations

This map shows the geographic impact of Nicholas Gekakis's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Nicholas Gekakis with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Nicholas Gekakis more than expected).

Fields of papers citing papers by Nicholas Gekakis

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Nicholas Gekakis. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Nicholas Gekakis. The network helps show where Nicholas Gekakis may publish in the future.

Co-authorship network of co-authors of Nicholas Gekakis

This figure shows the co-authorship network connecting the top 25 collaborators of Nicholas Gekakis. A scholar is included among the top collaborators of Nicholas Gekakis based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Nicholas Gekakis. Nicholas Gekakis is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Li, Yutong, et al.. (2018). Extraction Meets Abstraction: Ideal Answer Generation for Biomedical Questions. 57–65. 1 indexed citations

Pitman, Jeffrey L., Matthew C. Wheeler, David J. Lloyd, et al.. (2014). A Gain-of-Function Mutation in Adenylate Cyclase 3 Protects Mice from Diet-Induced Obesity. PLoS ONE. 9(10). e110226–e110226. 43 indexed citations

Wheeler, Matthew C. & Nicholas Gekakis. (2014). Hsp90 modulates PPARγ activity in a mouse model of nonalcoholic fatty liver disease. Journal of Lipid Research. 55(8). 1702–1710. 36 indexed citations

Wheeler, Matthew C. & Nicholas Gekakis. (2012). Defective ER associated degradation of a model luminal substrate in yeast carrying a mutation in the 4th ER luminal loop of Sec61p. Biochemical and Biophysical Research Communications. 427(4). 768–773. 8 indexed citations

Pitman, Jeffrey L., David J. Bonnet, Linda K. Curtiss, & Nicholas Gekakis. (2011). Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites. Journal of Lipid Research. 52(10). 1775–1786. 32 indexed citations

Huang, Shih-Min A., Michael K. Hancock, Jeffrey L. Pitman, Anthony P. Orth, & Nicholas Gekakis. (2009). Negative Regulators of Insulin Signaling Revealed in a Genome-Wide Functional Screen. PLoS ONE. 4(9). e6871–e6871. 29 indexed citations

Lloyd, David J., Matthew C. Wheeler, & Nicholas Gekakis. (2009). A Point Mutation in Sec61α1 Leads to Diabetes and Hepatosteatosis in Mice. Diabetes. 59(2). 460–470. 53 indexed citations

Zhao, Wen‐Ning, Nikolay Malinin, Fu‐Chia Yang, et al.. (2007). CIPC is a mammalian circadian clock protein without invertebrate homologues. Nature Cell Biology. 9(3). 268–275. 68 indexed citations

Lloyd, David J., et al.. (2006). Obesity, hyperphagia and increased metabolic efficiency in Pc1 mutant mice. Human Molecular Genetics. 15(11). 1884–1893. 105 indexed citations

10.

Li, Guochun, Raquel González de Vega, Keats Nelms, et al.. (2006). A Role for Alström Syndrome Protein, Alms1, in Kidney Ciliogenesis and Cellular Quiescence. PLoS Genetics. 3(1). e8–e8. 135 indexed citations

11.

Lloyd, David J., Frank W. Hall, Lisa M. Tarantino, & Nicholas Gekakis. (2005). Diabetes Insipidus in Mice with a Mutation in Aquaporin-2. PLoS Genetics. 1(2). e20–e20. 51 indexed citations

12.

Yin, Hongwei, et al.. (2003). Ubiquitin Signals Protein Trafficking via Interaction with a Novel Ubiquitin Binding Domain in the Membrane Fusion Regulator, Vps9p. Current Biology. 13(3). 258–262. 85 indexed citations

13.

Gekakis, Nicholas, David Staknis, Fred C. Davis, et al.. (1998). Role of the CLOCK Protein in the Mammalian Circadian Mechanism. Science. 280(5369). 1564–1569. 1643 indexed citations breakdown →

14.

Sáez, Lino, Marina P. Antoch, Nicholas Gekakis, et al.. (1998). Mammalian Circadian Autoregulatory Loop. Neuron. 21(5). 1101–1113. 312 indexed citations

15.

Darlington, Thomas K., Karen Wager‐Smith, M. Fernanda Ceriani, et al.. (1998). Closing the Circadian Loop: CLOCK-Induced Transcription of Its Own Inhibitors per and tim. Science. 280(5369). 1599–1603. 688 indexed citations breakdown →

16.

Gekakis, Nicholas, Lino Sáez, Michael P. Myers, et al.. (1995). Isolation of timeless by PER Protein Interaction: Defective Interaction Between timeless Protein and Long-Period Mutant PER ^L. Science. 270(5237). 811–815. 306 indexed citations

17.

Gekakis, Nicholas, et al.. (1994). Control of the Murine Phosphofructokinase-A Gene during Muscle Differentiation. Biochemistry. 33(7). 1771–1777. 6 indexed citations

18.

Gekakis, Nicholas, et al.. (1994). Structure, distribution, and functional expression of the phosphofructokinase C isozyme.. Journal of Biological Chemistry. 269(5). 3348–3355. 23 indexed citations

19.

Gekakis, Nicholas, et al.. (1989). Phosphofructokinase Isozyme Expression during Myoblast Differentiation. Journal of Biological Chemistry. 264(7). 3658–3661. 13 indexed citations

20.

Gekakis, Nicholas, et al.. (1988). Liver (B-type) phosphofructokinase mRNA. Cloning, structure, and expression.. Journal of Biological Chemistry. 263(24). 11755–11759. 44 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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