Motoyuki Otsuka

13.0k total citations · 3 hit papers
251 papers, 9.9k citations indexed

About

Motoyuki Otsuka is a scholar working on Molecular Biology, Epidemiology and Cancer Research. According to data from OpenAlex, Motoyuki Otsuka has authored 251 papers receiving a total of 9.9k indexed citations (citations by other indexed papers that have themselves been cited), including 112 papers in Molecular Biology, 61 papers in Epidemiology and 56 papers in Cancer Research. Recurrent topics in Motoyuki Otsuka's work include Hepatitis B Virus Studies (36 papers), MicroRNA in disease regulation (34 papers) and Hepatitis C virus research (33 papers). Motoyuki Otsuka is often cited by papers focused on Hepatitis B Virus Studies (36 papers), MicroRNA in disease regulation (34 papers) and Hepatitis C virus research (33 papers). Motoyuki Otsuka collaborates with scholars based in Japan, United States and China. Motoyuki Otsuka's co-authors include Kazuaki Yoshioka, Masao Omata, Kazuhiko Koike, Shiro Konishi, Takahiro Kishikawa, Naoya Kato, Young Jun Kang, Takeshi Yoshikawa, Akemi Takata and Haruhiko Yoshida and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Motoyuki Otsuka

223 papers receiving 9.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Correction: Corrigendum: MicroRNA122 is a key regulator of α-fetoprotein expression and influences the aggressiveness of hepatocellular carcinoma

2012 1.2k citations Akemi Takata, Motoyuki Otsuka et al. profile →
Neurotransmitter functions of mammalian tachykinins.

1993 937 citations Motoyuki Otsuka et al. profile →
Evidence-based clinical practice guidelines for nonalcoholic fatty liver disease/nonalcoholic steatohepatitis 2020

2021 179 citations Motoyuki Otsuka, Tomomi Kogiso et al. Journal of Gastroenterology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Motoyuki Otsuka Japan	53	4.4k	2.4k	1.7k	1.6k	1.4k	251	9.9k
Akira Tamura Japan	54	3.4k 0.8×	3.0k 1.3×	1.8k 1.0×	347 0.2×	540 0.4×	523	13.9k
Hiroshi Sasaki Japan	69	13.6k 3.1×	2.1k 0.9×	763 0.4×	691 0.4×	389 0.3×	433	21.4k
Calvin J. Kuo United States	67	10.9k 2.5×	1.4k 0.6×	826 0.5×	2.3k 1.4×	654 0.5×	139	20.9k
Masaru Okabe Japan	94	14.3k 3.2×	2.3k 1.0×	1.9k 1.1×	1.9k 1.2×	587 0.4×	404	30.5k
Jon A. Wolff United States	62	12.0k 2.7×	873 0.4×	1.1k 0.6×	591 0.4×	304 0.2×	177	17.4k
Takashi Yamamoto Japan	72	10.9k 2.5×	899 0.4×	1.7k 1.0×	1.4k 0.9×	222 0.2×	689	21.2k
Masahito Ikawa Japan	79	13.2k 3.0×	1.8k 0.7×	1.0k 0.6×	1.5k 1.0×	214 0.2×	407	23.5k
Paul K. Nakane Japan	44	5.2k 1.2×	1.2k 0.5×	1.1k 0.6×	567 0.4×	420 0.3×	146	12.6k
Shmuel A. Ben‐Sasson Israel	25	5.8k 1.3×	999 0.4×	686 0.4×	911 0.6×	221 0.2×	45	10.8k
Osamu Ohara Japan	67	7.6k 1.7×	1.1k 0.4×	1.0k 0.6×	1.1k 0.7×	217 0.2×	422	15.7k

Countries citing papers authored by Motoyuki Otsuka

Since Specialization

Citations

This map shows the geographic impact of Motoyuki Otsuka's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Motoyuki Otsuka with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Motoyuki Otsuka more than expected).

Fields of papers citing papers by Motoyuki Otsuka

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Motoyuki Otsuka. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Motoyuki Otsuka. The network helps show where Motoyuki Otsuka may publish in the future.

Co-authorship network of co-authors of Motoyuki Otsuka

This figure shows the co-authorship network connecting the top 25 collaborators of Motoyuki Otsuka. A scholar is included among the top collaborators of Motoyuki Otsuka based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Motoyuki Otsuka. Motoyuki Otsuka is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Horiguchi, Shigeru, Hironari Kato, Yuki Fujii, et al.. (2025). Microsatellite-high intrahepatic cholangiocarcinoma with favorable treatment outcome using pembrolizumab. Clinical Journal of Gastroenterology. 18(2). 363–368.

Kinugasa, Hideaki, Sakiko Hiraoka, Sayo Kobayashi, et al.. (2025). Acetic Acid-Indigo Carmine Chromocolonoscopy for Proximal Serrated Lesions: A Randomized, 3-Arm Colonoscopy Study. The American Journal of Gastroenterology. 120(12). 2877–2888.

Takaki, Akinobu, et al.. (2025). Cholecystectomy Is Linked to Worse Clinical Outcomes in Primary Sclerosing Cholangitis. Cureus. 17(3). e80184–e80184.

Kono, Yoshiyasu, Hideki Yamamoto, Daisuke Ennishi, et al.. (2025). Distinct age-related effects of homologous recombination deficiency on genomic profiling and treatment efficacy in gastric cancer. Journal of Gastroenterology. 60(10). 1232–1241.

Kishikawa, Takahiro, Takahiro Seimiya, Koji Miyabayashi, et al.. (2024). WWP1 inhibition suppresses the proliferation of pancreatic cancer cells by regulating the PI3K-AKT pathway. Journal of Gastroenterology. 60(3). 370–384.

Matsumoto, Kazuyuki, Hironari Kato, Takao Itoi, et al.. (2024). Efficacy and safety of endoscopic ultrasonography-guided ethanol injections of small pancreatic neuroendocrine neoplasms: a prospective multicenter study. Endoscopy. 57(4). 321–329. 3 indexed citations

Kawano, Seiji, Kenta Hamada, Yoshiyasu Kono, et al.. (2024). Characteristics of Early Gastric Cancer in a Patient with a History of<i> Helicobacter pylori</i> Infection and No History of Eradication Therapy. Internal Medicine. 64(3). 343–350.

Uchida, Daisuke, Ryosuke Sato, Kazuyuki Matsumoto, et al.. (2024). Effectiveness of data-augmentation on deep learning in evaluating rapid on-site cytopathology at endoscopic ultrasound-guided fine needle aspiration. Scientific Reports. 14(1). 22441–22441. 8 indexed citations

Matsueda, Katsunori, Seiji Kawano, Keisuke Fukui, et al.. (2024). Long‐term outcomes of endoscopic resection of superficial esophageal squamous cell carcinoma in late‐elderly patients. Journal of Gastroenterology and Hepatology. 39(12). 2664–2671. 1 indexed citations

10.

Otsuka, Motoyuki, Toshiharu Mitsuhashi, Yuichi Shimodate, et al.. (2023). Endoscopic evaluation by the Kyoto classification of gastritis combined with serum anti-Helicobacter pylori antibody testing reliably risk-stratifies subjects in a population-based gastric cancer screening program. Journal of Gastroenterology. 58(9). 848–855. 4 indexed citations

11.

Oyama, Atsushi, Akinobu Takaki, Takuya Adachi, et al.. (2023). Oxidative stress-related markers as prognostic factors for patients with primary sclerosing cholangitis in Japan. Hepatology International. 17(5). 1215–1224. 1 indexed citations

12.

Matsumoto, Kazuyuki, Takehiro Tanaka, Takeshi Tomoda, et al.. (2023). Cysts or necrotic components in pancreatic ductal adenocarcinoma is associated with the risk of EUS-FNA/B complications including needle tract seeding. Pancreatology. 23(8). 988–995.

13.

Sekiba, Kazuma, Motoyuki Otsuka, Eri Tanaka, et al.. (2021). HBx-induced degradation of Smc5/6 complex impairs homologous recombination-mediated repair of damaged DNA. Journal of Hepatology. 76(1). 53–62. 60 indexed citations

14.

Kakizaki, Masatoshi, Yuichiro Yamamoto, Motoyuki Otsuka, et al.. (2020). Extracellular vesicles secreted by HBV-infected cells modulate HBV persistence in hydrodynamic HBV transfection mouse model. Journal of Biological Chemistry. 295(35). 12449–12460. 22 indexed citations

15.

Kishikawa, Takahiro, Motoyuki Otsuka, Tatsunori Suzuki, et al.. (2018). Satellite RNA Increases DNA Damage and Accelerates Tumor Formation in Mouse Models of Pancreatic Cancer. Molecular Cancer Research. 16(8). 1255–1262. 11 indexed citations

16.

Kogiso, Tomomi, Hikaru Nagahara, Motoyuki Otsuka, Keiko Shiratori, & Steven F. Dowdy. (2013). Transdifferentiation of human fibroblasts into hepatocyte-like cells by defined transcriptional factors. Hepatology International. 7(3). 937–944. 22 indexed citations

17.

Takata, Akemi, Motoyuki Otsuka, Takeshi Yoshikawa, et al.. (2012). MicroRNA-140 acts as a liver tumor suppressor by controlling NF-κB activity by directly targeting DNA methyltransferase 1 (Dnmt1) expression. Hepatology. 57(1). 162–170. 85 indexed citations

18.

Tanaka, Takuya, et al.. (2009). Our experience of difficulties in removal of the locking plate. 31(1). 212–215. 1 indexed citations

19.

Muroyama, Ryosuke, Naoya Kato, Haruhiko Yoshida, et al.. (2006). Nucleotide change of codon 38 in the X gene of hepatitis B virus genotype C is associated with an increased risk of hepatocellular carcinoma. Journal of Hepatology. 45(6). 805–812. 56 indexed citations

20.

Otsuka, Motoyuki, Naoya Kato, Hiroyoshi Taniguchi, et al.. (2002). Hepatitis C Virus Core Protein Inhibits Apoptosis via Enhanced Bcl-xL Expression. Virology. 296(1). 84–93. 57 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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