Michihisa Umetani

5.0k total citations · 1 hit paper
43 papers, 3.9k citations indexed

About

Michihisa Umetani is a scholar working on Surgery, Molecular Biology and Genetics. According to data from OpenAlex, Michihisa Umetani has authored 43 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Surgery, 18 papers in Molecular Biology and 15 papers in Genetics. Recurrent topics in Michihisa Umetani's work include Cholesterol and Lipid Metabolism (18 papers), Estrogen and related hormone effects (15 papers) and Cancer, Lipids, and Metabolism (11 papers). Michihisa Umetani is often cited by papers focused on Cholesterol and Lipid Metabolism (18 papers), Estrogen and related hormone effects (15 papers) and Cancer, Lipids, and Metabolism (11 papers). Michihisa Umetani collaborates with scholars based in United States, Japan and Italy. Michihisa Umetani's co-authors include Philip W. Shaul, David J. Mangelsdorf, Donald P. McDonnell, Chieko Mineo, Ivan S. Yuhanna, Carolyn D. DuSell, Erik R. Nelson, Steven A. Kliewer, Tomonori Ishikawa and Matthew K. Howe and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Michihisa Umetani

43 papers receiving 3.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology

2013 632 citations Erik R. Nelson, Suzanne E. Wardell et al. Science profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michihisa Umetani United States	28	1.8k	1.7k	1.1k	976	964	43	3.9k
Torben Ørntoft Denmark	25	1.6k 0.9×	834 0.5×	748 0.7×	405 0.4×	604 0.6×	49	2.9k
Sahng Wook Park South Korea	24	1.9k 1.1×	2.5k 1.4×	1.1k 1.0×	410 0.4×	220 0.2×	53	4.4k
Goshi Shiota Japan	41	2.2k 1.2×	1.2k 0.7×	843 0.8×	788 0.8×	352 0.4×	165	5.4k
Suzanne E. Wardell United States	28	1.6k 0.9×	525 0.3×	1.0k 0.9×	930 1.0×	1.0k 1.1×	50	3.4k
Bernardo L. Trigatti Canada	34	2.4k 1.4×	2.8k 1.6×	834 0.7×	971 1.0×	312 0.3×	93	5.6k
Wilfried Le Goff France	34	1.2k 0.7×	2.2k 1.3×	762 0.7×	476 0.5×	288 0.3×	110	4.1k
Nicolas Duverger France	38	2.9k 1.6×	3.3k 1.9×	968 0.9×	1.3k 1.3×	493 0.5×	67	6.2k
Carrie L. Welch United States	33	2.8k 1.6×	2.2k 1.3×	1.4k 1.2×	983 1.0×	353 0.4×	64	6.3k
Jaap Twisk Netherlands	27	1.5k 0.8×	1.2k 0.7×	266 0.2×	754 0.8×	884 0.9×	49	2.9k
David P. Wade United Kingdom	23	1.6k 0.9×	2.5k 1.5×	822 0.7×	958 1.0×	187 0.2×	32	3.5k

Countries citing papers authored by Michihisa Umetani

Since Specialization

Citations

This map shows the geographic impact of Michihisa Umetani's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michihisa Umetani with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michihisa Umetani more than expected).

Fields of papers citing papers by Michihisa Umetani

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michihisa Umetani. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michihisa Umetani. The network helps show where Michihisa Umetani may publish in the future.

Co-authorship network of co-authors of Michihisa Umetani

This figure shows the co-authorship network connecting the top 25 collaborators of Michihisa Umetani. A scholar is included among the top collaborators of Michihisa Umetani based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michihisa Umetani. Michihisa Umetani is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Liu, Xiaohui, Jianjun Qi, Zihua Zeng, et al.. (2021). Neutralizing Aptamers Block S/RBD‐ACE2 Interactions and Prevent Host Cell Infection. Angewandte Chemie International Edition. 60(18). 10273–10278. 97 indexed citations

Liu, Xiaohui, Jianjun Qi, Zihua Zeng, et al.. (2021). Neutralizing Aptamers Block S/RBD‐ACE2 Interactions and Prevent Host Cell Infection. Angewandte Chemie. 133(18). 10361–10366. 18 indexed citations

Umetani, Michihisa, et al.. (2020). Obesity and Cancer: 27-Hydroxycholesterol, the Missing Link. International Journal of Molecular Sciences. 21(14). 4822–4822. 30 indexed citations

Ishikawa, Tomonori, Wan-Ru Lee, Christine Crumbley, et al.. (2018). Estrogen Receptor Beta-Mediated Modulation of Lung Cancer Cell Proliferation by 27-Hydroxycholesterol. Frontiers in Endocrinology. 9. 470–470. 31 indexed citations

Oguro, Hideyuki, Jeffrey G. McDonald, Zhiyu Zhao, et al.. (2017). 27-Hydroxycholesterol induces hematopoietic stem cell mobilization and extramedullary hematopoiesis during pregnancy. Journal of Clinical Investigation. 127(9). 3392–3401. 39 indexed citations

Nelson, Erik R., Suzanne E. Wardell, Jeff S. Jasper, et al.. (2013). 27-Hydroxycholesterol Links Hypercholesterolemia and Breast Cancer Pathophysiology. Science. 342(6162). 1094–1098. 632 indexed citations breakdown →

Ishikawa, Tomonori, Ivan S. Yuhanna, Junko Umetani, et al.. (2013). LXRβ/estrogen receptor-α signaling in lipid rafts preserves endothelial integrity. Journal of Clinical Investigation. 123(8). 3488–3497. 40 indexed citations

Umetani, Michihisa & Philip W. Shaul. (2011). 27-Hydroxycholesterol: the first identified endogenous SERM. Trends in Endocrinology and Metabolism. 22(4). 130–135. 91 indexed citations

Nelson, Erik R., Carolyn D. DuSell, Xiaojuan Wang, et al.. (2011). The Oxysterol, 27-Hydroxycholesterol, Links Cholesterol Metabolism to Bone Homeostasis Through Its Actions on the Estrogen and Liver X Receptors. Endocrinology. 152(12). 4691–4705. 102 indexed citations

10.

Wu, Qian, Ken L. Chambliss, Michihisa Umetani, Chieko Mineo, & Philip W. Shaul. (2011). Non-nuclear Estrogen Receptor Signaling in the Endothelium. Journal of Biological Chemistry. 286(17). 14737–14743. 81 indexed citations

11.

Umetani, Michihisa, David J. Mangelsdorf, & Philip W. Shaul. (2010). Abstract 18427: 27-Hydroxycholesterol, the First Identified endogenous SERM, Promotes Atherogenesis in Mice. Circulation. 122(2). 700–710. 2 indexed citations

12.

DuSell, Carolyn D., Erik R. Nelson, Xiaojuan Wang, et al.. (2010). The Endogenous Selective Estrogen Receptor Modulator 27-Hydroxycholesterol Is a Negative Regulator of Bone Homeostasis. Endocrinology. 151(8). 3675–3685. 88 indexed citations

13.

Chambliss, Ken L., Qian Wu, Sarah C. Oltmann, et al.. (2010). Non-nuclear estrogen receptor α signaling promotes cardiovascular protection but not uterine or breast cancer growth in mice. Journal of Clinical Investigation. 120(7). 2319–2330. 203 indexed citations

14.

Umetani, Michihisa, Hideharu Domoto, Andrew K. Gormley, et al.. (2007). 27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen. Nature Medicine. 13(10). 1185–1192. 303 indexed citations

15.

Horiuchi, Keiko, Michihisa Umetani, Takashi Minami, et al.. (2006). Wilms' tumor 1-associating protein regulates G ₂ /M transition through stabilization of cyclin A2 mRNA. Proceedings of the National Academy of Sciences. 103(46). 17278–17283. 122 indexed citations

16.

Yang, Chendong, Jeffrey G. McDonald, Amit Patel, et al.. (2006). Sterol Intermediates from Cholesterol Biosynthetic Pathway as Liver X Receptor Ligands. Journal of Biological Chemistry. 281(38). 27816–27826. 232 indexed citations

17.

Choi, Mihwa, Antonio Moschetta, Angie L. Bookout, et al.. (2006). Identification of a hormonal basis for gallbladder filling. Nature Medicine. 12(11). 1253–1255. 232 indexed citations

18.

Iwasaki, Akio, et al.. (2002). Affinity improvement of the high-affinity immunoglobulin E receptor by phage display. Biochemical and Biophysical Research Communications. 293(1). 542–548. 1 indexed citations

19.

Saiura, Akio, Chikage Mataki, Takeshi Murakami, et al.. (2001). A COMPARISON OF GENE EXPRESSION IN MURINE CARDIAC ALLOGRAFTS AND ISOGRAFTS BY MEANS DNA MICROARRAY ANALYSIS1. Transplantation. 72(2). 320–329. 52 indexed citations

20.

Nakao, Hiroshi, Takeshi Doi, M Suda, et al.. (1998). An Inhibitor of VCAM-1 Expression and Its Implication as a Novel Treatment of Inflammatory Diseases. Journal of Atherosclerosis and Thrombosis. 4(4). 149–155. 4 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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