Jaap Twisk

3.6k citations

49 papers · 2.9k indexed · h-index 27

Impact in

Genetics top 2%
- Virus-based gene therapy research
Endocrinology, Diabetes and Metabolism top 2%
- Diabetes, Cardiovascular Risks, and Lipoproteins

Papers in

Genetics 25
- Virus-based gene therapy research 15
- Diabetes and associated disorders 14
Oncology 18
- Drug Transport and Resistance Mechanisms 12

Co-authors: Theo J.C. van Berkel Miranda Van Eck P. Hans Daniel Gaudet Diane Brisson I. Sophie T. Bos Julie Méthot J. de Wal
Journals: Human Gene Therapy (8 papers)Biochemical Journal (4 papers)Arteriosclerosis Thrombosis and Vascular Biology (3 papers)Journal of Clinical Investigation (2 papers)Atherosclerosis Supplements (2 papers)
Partner nations: Netherlands Canada Germany

In The Last Decade

Jaap Twisk

49 papers receiving 2.8k citations

Peers

Countries citing papers authored by Jaap Twisk

Since Specialization

Citations

This map shows the geographic impact of Jaap Twisk's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jaap Twisk with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jaap Twisk more than expected).

Fields of papers citing papers by Jaap Twisk

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jaap Twisk. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jaap Twisk. The network helps show where Jaap Twisk may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jaap Twisk, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jaap Twisk Line = papers co-authored together Jaap Twisk links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Immune Responses to Intramuscular Administration of Alipogene Tiparvovec (AAV1-LPL ^S447X ) in a Phase II Clinical Trial of Lipoprotein Lipase Deficiency Gene Therapy Human Gene Therapy ·Valérie Ferreira, Jaap Twisk, Karin L. Kwikkers, Eleonora Aronica, Diane Brisson, Julie Méthot, Harald Petry, Daniel Gaudet	2013	107
2	Effect of Alipogene Tiparvovec (AAV1-LPL^S447X) on Postprandial Chylomicron Metabolism in Lipoprotein Lipase-Deficient Patients The Journal of Clinical Endocrinology & Metabolism ·André C. Carpentier, Frédérique Frisch, Sébastien M. Labbé, René Gagnon, J. de Wal, 徹清水, Harald Petry, Jaap Twisk, Diane Brisson, Daniel Gaudet	2012	122
3	Abstract 16900: Gene Therapy With Alipogene Tiparvovec Results in Enhanced Post-Prandial Clearance of Low Density Chylomicrons in LPLD Patients Circulation ·André C. Carpentier, Frédérique Frisch, Sébastien M. Labbé, Julie Méthot, Claude Gagné, S. Déry, Karine Tremblay, J. de Wal, Jaap Twisk, Andreas P. Freidig, Diane Brisson, Daniel Gaudet	2010	2
4	Sustained Enzymatic Correction by rAAV-Mediated Liver Gene Therapy Protects Against Induced Motor Neuropathy in Acute Porphyria Mice Molecular Therapy ·Carmen Unzu, Ana Sampedro, Itsaso Mauleón, Manuel Alegre, Stuart G. Beattie, Rafael Enrı́quez de Salamanca, Jolanda Snapper, Jaap Twisk, Harald Petry, Gloria González‐Aseguinolaza, Julio Artieda, Maria Sol Rodríguez-Peña, Jesús Prìeto, Antonio Fontanellas	2010	50
5	AAV gene therapy as a means to increase apolipoprotein (Apo) A‐I and high‐density lipoprotein‐cholesterol levels: correction of murine ApoA‐I deficiency The Journal of Gene Medicine ·Stefan F.C. Vaessen, Robert Jan Veldman, Hermine de Knijff, Jolanda Snapper, Jeroen A. Sierts, Karin van den Oever, Stuart G. Beattie, Jaap Twisk, Jan Albert Kuivenhoven	2009	14
6	Adeno-associated viral vector (AAV)-mediated gene transfer in the red nucleus of the adult rat brain: Comparative analysis of the transduction properties of seven AAV serotypes and lentiviral vectors Journal of Neuroscience Methods ·Bas Blits, S. Ya. Mokryak, Jaap Twisk, Erich Ehlert, Jolanda Prins, Joost Verhaagen	2009	52
7	Intramuscular Administration of AAV1-Lipoprotein Lipase ^S447X Lowers Triglycerides in Lipoprotein Lipase–Deficient Patients Arteriosclerosis Thrombosis and Vascular Biology ·Erik S.G. Stroes, Melchior C. Nierman, J. J. M. Meulenberg, Remco Franssen, Jaap Twisk, C. P. Henny, Mario Maas, Aeilko H. Zwinderman, Colin J.D. Ross, Eleonora Aronica, Katherine A. High, Marcel M. Levi, Michael R. Hayden, John J.P. Kastelein, Jan Albert Kuivenhoven	2008	145
8	Gene Therapy in Disorders of Lipoprotein Metabolism Current Gene Therapy ·Stefan F.C. Vaessen, Jaap Twisk, John J.P. Kastelein, Jan Albert Kuivenhoven	2007	10
9	AAV1-LPLS447X gene therapy reduces hypertriglyceridemia in apoE2 knock in mice Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids ·Jaap Rip, Ko Willems van Dijk, Jeroen A. Sierts, John J.P. Kastelein, Jaap Twisk, Jan Albert Kuivenhoven	2006	11
10	Adeno-associated Virus Vector Serotypes Mediate Sustained Correction of Bilirubin UDP Glucuronosyltransferase Deficiency in Rats Molecular Therapy ·Jurgen Seppen, Conny Bakker, Puja Tripathi, Cindy Kunne, Karin van den Oever, F. P. GORTSEMA, Rudi de Waart, Jaap Twisk, Piter J. Bosma	2006	68
11	Adeno-associated virus LPLS447X gene therapy in LDL receptor knockout mice Atherosclerosis ·Jaap Rip, Jeroen A. Sierts, Stefan F.C. Vaessen, John J.P. Kastelein, Jaap Twisk, Jan Albert Kuivenhoven	2006	5
12	Scavenger receptor class B type I is solely responsible for the selective uptake of cholesteryl esters from HDL by the liver and the adrenals in mice Journal of Lipid Research ·Ruud Out, Menno Hoekstra, Prajakta Vilas Thakar, J. Kar Kruijt, Miranda Van Eck, W. Adam, Jaap Twisk, Theo J.C. van Berkel	2004	110
13	Long-Term Correction of Murine Lipoprotein Lipase Deficiency with AAV1-Mediated Gene Transfer of the Naturally Occurring LPL ^S447X Beneficial Mutation Human Gene Therapy ·Colin J.D. Ross, Jaap Twisk, Cruz Roja de Yugoslavia, Guoqing Liu, Karin van den Oever, Mariyah Saripah Saripah Nurfilah, Wim Th. Hermens, Jaap Rip, John J.P. Kastelein, Jan Albert Kuivenhoven, Michael R. Hayden	2004	63
14	Comparison of E-selectin expression at mRNA and protein levels in murine models of inflammation Inflammation Research ·Mary Salazar-Guenther, Grietje Molema, Maaike Everts, Xingyuan Kang, Robbert J. Kok, Jaap Twisk, Bart de Vries, Erik Lubberts, Valiantsin Ramanouski, 橋本和宣	2003	8
15	Differential Effects of Scavenger Receptor BI Deficiency on Lipid Metabolism in Cells of the Arterial Wall and in the Liver Journal of Biological Chemistry ·Miranda Van Eck, Jaap Twisk, Menno Hoekstra, Xiaohui Liu, Carlos Ronaldo Mancha Feria, I. Sophie T. Bos, J. Kar Kruijt, Folkert Kuipers, Theo J.C. van Berkel	2003	198
16	The role of the LDL receptor in apolipoprotein B secretion Journal of Clinical Investigation ·Jaap Twisk, Donald L. Gillian‐Daniel, Jessica Maciel Winckievicz, Lin Wang, P. Hugh R. Barrett, Alan Attie	2000	199
17	Heterogeneous expression of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase genes in the rat liver lobulus. Journal of Clinical Investigation ·Jaap Twisk, Marco F.M. Hoekman, W.H. Mager, Antoon F.M. Moorman, Piet A. J. de Boer, Ludger Scheja, (unknown), Rolf Gebhardt	1995	63
18	Structural Aspects of Bile Acids Involved in the Regulation of Cholesterol 7α‐Hydroxylase and Sterol 27‐Hydroxylase European Journal of Biochemistry ·Jaap Twisk, Marco F.M. Hoekman, Bharti Joshi, Takashi Iida, Martin Dinh, Adriaan P. IJzerman, Willem H. Mager, P. Hans	1995	18
19	Transcriptional regulation of the gene encoding cholesterol 7α-hydroxylase in the rat Gene ·Marco F.M. Hoekman, Julian F Silva, Jaap Twisk, Rudi J. Planta, P. Hans, Willem H. Mager	1994	3
20	Transcriptional regulation of the gene encoding cholesterol 7α-hydroxylase in the rat Gene ·Marco F.M. Hoekman, Julian F Silva, Jaap Twisk, Rudi J. Planta, P. Hans, Willem H. Mager	1993	36

About Jaap Twisk

Jaap Twisk is a scholar working on Genetics, Oncology, Cardiology and Cardiovascular Medicine, Endocrinology, Diabetes and Metabolism and Surgery, having authored 49 papers that have together received 2.9k indexed citations. Recurring topics across this work include Virus-based gene therapy research (15 papers), Cholesterol and Lipid Metabolism (15 papers), Diabetes and associated disorders (14 papers), Drug Transport and Resistance Mechanisms (12 papers), Lipid metabolism and disorders (9 papers), Liver Disease Diagnosis and Treatment (4 papers), Cancer, Lipids, and Metabolism (4 papers) and CRISPR and Genetic Engineering (4 papers). The work is most often cited by research in Genetics (884 citations), Endocrinology, Diabetes and Metabolism (522 citations), Oncology (754 citations), Surgery (1.2k citations) and Cardiology and Cardiovascular Medicine (543 citations). Jaap Twisk has collaborated with scholars based in Netherlands, Canada and Germany. Frequent co-authors include Theo J.C. van Berkel, Miranda Van Eck, P. Hans, Daniel Gaudet, Diane Brisson, I. Sophie T. Bos, Julie Méthot, J. de Wal, Jan Albert Kuivenhoven and John J.P. Kastelein. Their work appears in journals such as Human Gene Therapy, Biochemical Journal, Arteriosclerosis Thrombosis and Vascular Biology, Journal of Clinical Investigation and Atherosclerosis Supplements.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact