Leonard C. Edelstein

5.2k total citations · 2 hit papers
49 papers, 3.9k citations indexed

About

Leonard C. Edelstein is a scholar working on Molecular Biology, Cancer Research and Hematology. According to data from OpenAlex, Leonard C. Edelstein has authored 49 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 25 papers in Cancer Research and 21 papers in Hematology. Recurrent topics in Leonard C. Edelstein's work include Platelet Disorders and Treatments (20 papers), MicroRNA in disease regulation (15 papers) and Cancer-related molecular mechanisms research (14 papers). Leonard C. Edelstein is often cited by papers focused on Platelet Disorders and Treatments (20 papers), MicroRNA in disease regulation (15 papers) and Cancer-related molecular mechanisms research (14 papers). Leonard C. Edelstein collaborates with scholars based in United States, Italy and United Kingdom. Leonard C. Edelstein's co-authors include Céline Gélinas, Cailin Chen, Paul F. Bray, Chi Chen, Jerry A. Bash, Chad A. Shaw, Steven E. McKenzie, Srikanth Nagalla, Tucker Collins and Michael Holinstat and has published in prestigious journals such as Journal of Biological Chemistry, Circulation and Nature Medicine.

In The Last Decade

Leonard C. Edelstein

48 papers receiving 3.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-x _L

2000 655 citations Cailin Chen, Leonard C. Edelstein et al. Molecular and Cellular Biology profile →
The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappa B that blocks TNFalpha -induced apoptosis

1999 628 citations Leonard C. Edelstein, Chi Chen et al. Genes & Development profile →

Peers

Leonard C. Edelstein

IMMUN

HEMAT

ONCOL

Paul Coughlin Australia

Yoshikuni Nagamine Switzerland

Brenda L. Coomber Canada

Wolf‐Dieter Schleuning Germany

Kenji Oritani Japan

Nikolay Malinin United States

Mei Huang China

Daoxin Ma China

Dimitris L. Kontoyiannis Greece

Tanya N. Mayadas United States

Paul Coughlin Australia

Leonard C. Edelstein

965 ×0.4

905 ×0.6

530 ×0.7

IMMUN

726 ×1.0

HEMAT

342 ×0.5

ONCOL

Citations per year, relative to Leonard C. Edelstein Leonard C. Edelstein (= 1×) peers Paul Coughlin

Countries citing papers authored by Leonard C. Edelstein

Since Specialization

Citations

This map shows the geographic impact of Leonard C. Edelstein's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Leonard C. Edelstein with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Leonard C. Edelstein more than expected).

Fields of papers citing papers by Leonard C. Edelstein

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Leonard C. Edelstein. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Leonard C. Edelstein. The network helps show where Leonard C. Edelstein may publish in the future.

Co-authorship network of co-authors of Leonard C. Edelstein

This figure shows the co-authorship network connecting the top 25 collaborators of Leonard C. Edelstein. A scholar is included among the top collaborators of Leonard C. Edelstein based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Leonard C. Edelstein. Leonard C. Edelstein is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Michael, James V., Xianguo Kong, Lin Ma, et al.. (2022). Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice. Journal of Thrombosis and Haemostasis. 20(5). 1236–1247. 7 indexed citations

Abraham, Shaji, et al.. (2021). PCTP contributes to human platelet activation by enhancing dense granule secretion. Thrombosis Research. 202. 67–73. 1 indexed citations

Ghazi, Andrew R., et al.. (2020). Bayesian modelling of high-throughput sequencing assays with malacoda. PLoS Computational Biology. 16(7). e1007504–e1007504. 3 indexed citations

Ghazi, Andrew R., et al.. (2019). Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis. PLoS Genetics. 15(7). e1008287–e1008287. 8 indexed citations

Kong, Xianguo, et al.. (2019). Validation of a Miniaturized Permeability Assay Compatible with CRISPR-Mediated Genome-Wide Screen. Scientific Reports. 9(1). 14238–14238. 1 indexed citations

Bhatlekar, Seema, Indranil Basak, Leonard C. Edelstein, et al.. (2019). Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood. Haematologica. 104(10). 2075–2083. 22 indexed citations

Tricoci, Pierluigi, Megan L. Neely, Leonard C. Edelstein, et al.. (2018). Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial. Blood Cells Molecules and Diseases. 72. 37–43. 7 indexed citations

Henke, David, Andrew R. Ghazi, Marvin T. Nieman, et al.. (2018). The protease‐activated receptor 4 Ala120Thr variant alters platelet responsiveness to low‐dose thrombin and protease‐activated receptor 4 desensitization, and is blocked by non‐competitive P2Y12 inhibition. Journal of Thrombosis and Haemostasis. 16(12). 2501–2514. 20 indexed citations

Kong, Xianguo, et al.. (2017). Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP. Thrombosis and Haemostasis. 117(5). 962–970. 4 indexed citations

10.

Teruel‐Montoya, Raúl, Xianguo Kong, Shaji Abraham, et al.. (2014). MicroRNA Expression Differences in Human Hematopoietic Cell Lineages Enable Regulated Transgene Expression. PLoS ONE. 9(7). e102259–e102259. 70 indexed citations

11.

Edelstein, Leonard C., Lukas M. Simon, Michael Holinstat, et al.. (2013). Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c. Nature Medicine. 19(12). 1609–1616. 161 indexed citations

12.

Edelstein, Leonard C., Steven E. McKenzie, Chad A. Shaw, et al.. (2013). MicroRNAs in platelet production and activation. Journal of Thrombosis and Haemostasis. 11. 340–350. 79 indexed citations

13.

Bray, Paul F., Steven E. McKenzie, Leonard C. Edelstein, et al.. (2013). The complex transcriptional landscape of the anucleate human platelet. BMC Genomics. 14(1). 1–1. 407 indexed citations

14.

Micheva‐Viteva, Sofiya, Yoshifumi Kobayashi, Leonard C. Edelstein, et al.. (2011). High-throughput Screening Uncovers a Compound That Activates Latent HIV-1 and Acts Cooperatively with a Histone Deacetylase (HDAC) Inhibitor. Journal of Biological Chemistry. 286(24). 21083–21091. 37 indexed citations

15.

Edelstein, Leonard C., et al.. (2009). Short Communication: Activation of Latent HIV Type 1 Gene Expression by Suberoylanilide Hydroxamic Acid (SAHA), an HDAC Inhibitor Approved for Use to Treat Cutaneous T Cell Lymphoma. AIDS Research and Human Retroviruses. 25(9). 883–887. 57 indexed citations

16.

Edelstein, Leonard C., Amy Pan, & Tucker Collins. (2005). Chromatin Modification and the Endothelial-specific Activation of the E-selectin Gene. Journal of Biological Chemistry. 280(12). 11192–11202. 58 indexed citations

17.

Edelstein, Leonard C. & Tucker Collins. (2005). The SCAN domain family of zinc finger transcription factors. Gene. 359. 1–17. 101 indexed citations

18.

Suh, Junghan, Faribourz Payvandi, Leonard C. Edelstein, et al.. (2002). Mechanisms of constitutive NF‐κB activation in human prostate cancer cells. The Prostate. 52(3). 183–200. 201 indexed citations

19.

Chen, Cailin, Leonard C. Edelstein, & Céline Gélinas. (2000). The Rel/NF-κB Family Directly Activates Expression of the Apoptosis Inhibitor Bcl-x _L. Molecular and Cellular Biology. 20(8). 2687–2695. 655 indexed citations breakdown →

20.

Edelstein, Leonard C., et al.. (1999). The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappa B that blocks TNFalpha -induced apoptosis. Genes & Development. 13(4). 382–387. 628 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact