Michael Frezza

2.3k citations

15 papers · 1.9k indexed · 2 hit papers · h-index 14

Oncology top 2%
- Metal complexes synthesis and properties 9
Organic Chemistry top 5%
- Synthesis of β-Lactam Compounds 3
- Synthesis and Catalytic Reactions 3
- Ferrocene Chemistry and Applications 2
Inorganic Chemistry top 10%
Hematology top 5%
Molecular Biology top 10%
- Ubiquitin and proteasome pathways 5
- Cell death mechanisms and regulation 2
Nutrition and Dietetics
- Trace Elements in Health 2
Computational Theory and Mathematics
- Computational Drug Discovery Methods 2

Co-authors: Q. Ping Dou Sara M. Schmitt Jyoti Kanwar S.S. Hindo Dajena Tomco Di Chen Andrew M. Davenport Vesna Milacic
Cited by: Oncology Organic Chemistry Inorganic Chemistry
Journals: Current Pharmaceutical Design (2 papers)European Journal of Medicinal Chemistry (1 paper)Current Cancer Drug Targets (1 paper)
Partner nations: United States China Italy

In The Last Decade

Michael Frezza

15 papers receiving 1.9k citations

Hit Papers

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Peers

Countries citing papers authored by Michael Frezza

Since Specialization

Citations

This map shows the geographic impact of Michael Frezza's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Frezza with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Frezza more than expected).

Fields of papers citing papers by Michael Frezza

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Frezza. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Frezza. The network helps show where Michael Frezza may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Michael Frezza, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael Frezza Line = papers co-authored together Michael Frezza links everyone, so they are left out of the graph.

All Works

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15 of 15 papers shown

#	Work
1	Bortezomib as the First Proteasome Inhibitor Anticancer Drug: Current Status and Future Perspectivesbreakdown → Current Cancer Drug Targets ·Elcin Huseynov,Michael Frezza,Sara M. Schmitt,Jyoti Kanwar,Q. Ping Dou	2011	640
2	Targeting the Ubiquitin-Proteasome Pathway: An Emerging Concept in Cancer Therapy Current Topics in Medicinal Chemistry ·Michael Frezza,Sara M. Schmitt,Q. Ping Dou	2011	71
3	Modulation of the tumor cell death pathway by androgen receptor in response to cytotoxic stimuli Journal of Cellular Physiology ·Michael Frezza,Huanjie Yang,Q. Ping Dou	2011	13
4	In Vitro and In Vivo Antitumor Activities and DNA Binding Mode of Five Coordinated Cyclometalated Organoplatinum(II) Complexes Containing Biphosphine Ligands Journal of Medicinal Chemistry ·Michael Frezza,Q. Ping Dou,Yan Xiao,Hamidreza Samouei,Mehdi Rashidi,Fayezeh Samari,Bahram Hemmateenejad	2011	71
5	Turning Tumor-Promoting Copper into an Anti-Cancer Weapon via High-Throughput Chemistry Current Medicinal Chemistry ·Guo dong Feng,Peifu Jiao,Min Qi,Michael Frezza,Q. Ping Dou,Bing Yan	2010	91
6	Novel Metals and Metal Complexes as Platforms for Cancer Therapybreakdown → Current Pharmaceutical Design ·Michael Frezza,S.S. Hindo,Di Chen,Andrew M. Davenport,Sara M. Schmitt,Dajena Tomco,Q. Ping Dou	2010	462
7	Metals in anticancer therapy: Copper(II) complexes as inhibitors of the 20S proteasome European Journal of Medicinal Chemistry ·S.S. Hindo,Michael Frezza,Dajena Tomco,Mary Jane Heeg,L.M. Hryhorczuk,Bruce R. McGarvey,Q. Ping Dou,Cláudio N. Verani	2009	87
8	Inhibition of tumor proteasome activity by gold–dithiocarbamato complexes via both redox‐dependent and ‐independent processes Journal of Cellular Biochemistry ·Xia Zhang,Michael Frezza,Vesna Milacic,Luca Ronconi,Yuhua Fan,Caifeng Bi,Dolores Fregona,Q. Ping Dou	2009	102
9	Metal Complexes, their Cellular Targets and Potential for Cancer Therapy Current Pharmaceutical Design ·Di Chen,Vesna Milacic,Michael Frezza,Q. Ping Dou	2009	143
10	Comparative Activities of Nickel(II) and Zinc(II) Complexes of Asymmetric [NN′O] Ligands as 26S Proteasome Inhibitors Inorganic Chemistry ·Michael Frezza,S.S. Hindo,Dajena Tomco,M. ALLARD,Qiuzhi Cindy Cui,Mary Jane Heeg,Di Chen,Q. Ping Dou,Cláudio N. Verani	2009	59
11	Anti-tumor activity of N-thiolated β-lactam antibiotics Cancer Letters ·Di Chen,Marcélia Basto da Silva,Michael Frezza,Vesna Milacic,Aslamuzzaman Kazi,Qiuzhi Cindy Cui,Timothy E. Long,Edward Turos,Q. Ping Dou	2008	40
12	Induction of tumor cell apoptosis by a novel class of N-thiolated beta-lactam antibiotics with structural modifications at N1 and C3 of the lactam ring. PubMed ·Michael Frezza,Johanna Maxeiner,Di Chen,Bereich Ur und Frühgeschichte,Edward Turos,Q. Ping Dou	2008	16
13	Induction of tumor cell apoptosis by a novel class of N-thiolated β-lactam antibiotics with structural modifications at N1 and C3 of the lactam ring International Journal of Molecular Medicine ·Michael Frezza,Johanna Maxeiner,Di Chen,Bereich Ur und Frühgeschichte,Edward Turos,Q. Ping Dou	2008	3
14	Inhibition of the Proteasome Activity by Gallium(III) Complexes Contributes to Their Anti–Prostate Tumor Effects Cancer Research ·Di Chen,Michael Frezza,R. Shakya,Qiuzhi Cindy Cui,Vesna Milacic,Cláudio N. Verani,Q. Ping Dou	2007	86
15	The Therapeutic Potential of Gallium-Based Complexes in Anti-Tumor Drug Design Letters in Drug Design & Discovery ·Michael Frezza,Cláudio N. Verani,Di Chen,Q. Ping Dou	2007	31

About Michael Frezza

Michael Frezza is a scholar working on Oncology, Organic Chemistry and Inorganic Chemistry, having authored 15 papers that have together received 1.9k indexed citations. Recurring topics across this work include Metal complexes synthesis and properties (9 papers), Ubiquitin and proteasome pathways (5 papers), Synthesis of β-Lactam Compounds (3 papers), Synthesis and Catalytic Reactions (3 papers), Cell death mechanisms and regulation (2 papers), Ferrocene Chemistry and Applications (2 papers), Trace Elements in Health (2 papers) and Computational Drug Discovery Methods (2 papers). The work is most often cited by research in Oncology (1.0k citations), Organic Chemistry (640 citations) and Inorganic Chemistry (192 citations). Michael Frezza has collaborated with scholars based in United States, China and Italy. Frequent co-authors include Q. Ping Dou, Sara M. Schmitt, Jyoti Kanwar, S.S. Hindo, Dajena Tomco, Di Chen, Andrew M. Davenport, Vesna Milacic, Di Chen and Cláudio N. Verani. Their work appears in journals such as Current Pharmaceutical Design, European Journal of Medicinal Chemistry, Current Cancer Drug Targets, Journal of Cellular Biochemistry and Current Topics in Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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