Saverio Tardito

5.9k citations

37 papers · 3.1k indexed · 2 hit papers · h-index 24

Co-authors: Luciano Marchiò Eyal Gottlieb Ovidio Bussolati R. Franchi‐Gazzola Tobias Ackermann Matteo Tegoni Claudio Mucchino Irene Bassanetti
Topics: Cancer, Hypoxia, and Metabolism (14 papers)Metal complexes synthesis and properties (7 papers)Amino Acid Enzymes and Metabolism (4 papers)
Cited by: Cancer Research Oncology Genetics
Journals: Journal of the American Chemical Society Journal of Biological Chemistry Nature Medicine
Partner nations: Italy United Kingdom Israel

In The Last Decade

Saverio Tardito

37 papers receiving 3.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

2015 426 citations Saverio Tardito, Anaïs Oudin et al. Nature Cell Biology profile →
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

2017 376 citations Alison M. Michie, Karen Dunn et al. profile →

Peers

Countries citing papers authored by Saverio Tardito

Since Specialization

Citations

This map shows the geographic impact of Saverio Tardito's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saverio Tardito with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saverio Tardito more than expected).

Fields of papers citing papers by Saverio Tardito

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saverio Tardito. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saverio Tardito. The network helps show where Saverio Tardito may publish in the future.

Co-authorship network of co-authors of Saverio Tardito

This figure shows the co-authorship network connecting the top 25 collaborators of Saverio Tardito. A scholar is included among the top collaborators of Saverio Tardito based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saverio Tardito. Saverio Tardito is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis 2024 ·EMBO Molecular Medicine ·Tobias Ackermann,Engy Shokry,(unknown),(unknown),Laura C.A. Galbraith,Louise Mitchell,Giovanny Rodriguez Blanco,Víctor H. Villar,(unknown),Colin Nixon,Sara Zanivan,Karen Blyth,David Sumpton,Saverio Tardito	7
2	Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia 2024 ·Science Translational Medicine ·(unknown),(unknown),Eric R. Kalkman,(unknown),(unknown),Joe M. Jones,Daniel James,Engy Shokry,Mary T. Scott,Karen Dunn,Saverio Tardito,Mhairi Copland,David Sumpton,Emma Shanks,G. Vignir Helgason	3
3	Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells 2023 ·Nature Communications ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Eric R. Kalkman,Mary T. Scott,Karen Dunn,David Sumpton,Alison M. Michie,Mhairi Copland,Saverio Tardito,Eyal Gottlieb,G. Vignir Helgason	13
4	Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells 2023 ·EMBO Reports ·(unknown),(unknown),(unknown),(unknown),(unknown),(unknown),Eric R. Kalkman,(unknown),Mary T. Scott,Karen Dunn,Engy Shokry,David Sumpton,Mhairi Copland,Saverio Tardito,Johan Vande Voorde,Francis Mussai,Paul Cheng,G. Vignir Helgason	5
5	Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis 2022 ·Developmental Cell ·(unknown),Giovanna Pontarin,Matteo Astone,(unknown),Liaisan Arslanbaeva,Giovanni Tosi,Emiliano Panieri,Sara Ricciardi,Maria Francesca Allega,Alessia Brossa,Paolo Grumati,Benedetta Bussolati,Stefano Biffo,Saverio Tardito,Massimo Santoro	29
6	ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment 2021 ·Blood Advances ·Martina Chiu,Giuseppe Taurino,Erica Dander,Donatella Bardelli,(unknown),Roberta Andreoli,Massimiliano G. Bianchi,Cecilia Carubbi,Giulia Pozzi,(unknown),Prisco Mirandola,Carmelo Rizzari,Saverio Tardito,Andrea Biondi,Giovanna D’Amico,Ovidio Bussolati	23
7	A map of the altered glioma metabolism 2021 ·Trends in Molecular Medicine ·(unknown),Maria Francesca Allega,Saverio Tardito	36
8	Improving the metabolic fidelity of cancer models with a physiological cell culture medium 2019 ·Science Advances ·Johan Vande Voorde,Tobias Ackermann,(unknown),David Sumpton,Gillian Mackay,Gabriela Kalna,Colin Nixon,Karen Blyth,Eyal Gottlieb,Saverio Tardito	235
9	Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells 2019 ·Nature Metabolism ·Isabelle Clerc,(unknown),(unknown),Saverio Tardito,Leal Oburoglu,Thomas J. Hope,Marc Sitbon,Valérie Dardalhon,Cédric Mongellaz,Naomi Taylor	67
10	Cell Culture Medium Formulation and Its Implications in Cancer Metabolism 2019 ·Trends in cancer ·Tobias Ackermann,Saverio Tardito	98
11	Altered metabolic landscape in IDH ‐mutant gliomas affects phospholipid, energy, and oxidative stress pathways 2017 ·EMBO Molecular Medicine ·Fred Fack,Saverio Tardito,(unknown),Anaïs Oudin,Liang Zheng,Sabrina Fritah,Anna Golebiewska,Petr V. Nazarov,(unknown),Ann‐Christin Hau,Olivier Keunen,William P. J. Leenders,Morten Lund‐Johansen,Jonathan Stauber,Eyal Gottlieb,Rolf Bjerkvig,Simone P. Niclou	108
12	Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastomabreakdown → 2015 ·Nature Cell Biology ·Saverio Tardito,Anaïs Oudin,Shafiq U. Ahmed,Fred Fack,Olivier Keunen,Liang Zheng,Hrvoje Miletić,Per Øystein Sakariassen,(unknown),Allon Wagner,Susan L. Lindsay,Andreas Hock,Susan C. Barnett,Eytan Ruppin,Svein Harald Mørkve,Morten Lund‐Johansen,Anthony J. Chalmers,Rolf Bjerkvig,Simone P. Niclou,Eyal Gottlieb	426
13	Polyphenon E®, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis 2013 ·Carcinogenesis ·Federica Rizzi,Valeria Naponelli,(unknown),(unknown),Ileana Ramazzina,Martina Bonacini,Saverio Tardito,Rita Gatti,Jacopo Uggeri,Saverio Bettuzzi	51
14	Glutamine stimulates mTORC1 independent of the cell content of essential amino acids 2012 ·Amino Acids ·Martina Chiu,Saverio Tardito,Amelia Barilli,Massimiliano G. Bianchi,Valeria Dall’Asta,Ovidio Bussolati	27
15	L-Asparaginase and Inhibitors of Glutamine Synthetase Disclose Glutamine Addiction of β-Catenin-Mutated Human Hepatocellular Carcinoma Cells 2011 ·Current Cancer Drug Targets ·Saverio Tardito,Martina Chiu,Jacopo Uggeri,(unknown),Alessandro Zerbini,Valeria Dall’Asta,Gabriele Missale,Ovidio Bussolati	43
16	The non-proteinogenic amino acids l-methionine sulfoximine and dl-phosphinothricin activate mTOR 2011 ·Amino Acids ·Saverio Tardito,Martina Chiu,R. Franchi‐Gazzola,Valeria Dall’Asta,Paola Comi,Ovidio Bussolati	9
17	Synthesis, structural characterisation and solution chemistry of ruthenium(III) triazole-thiadiazine complexes 2009 ·Dalton Transactions ·Massimiliano Delferro,Luciano Marchiò,Matteo Tegoni,Saverio Tardito,R. Franchi‐Gazzola,Maurizio Lanfranchi	13
18	Copper Compounds in Anticancer Strategies 2009 ·Current Medicinal Chemistry ·Saverio Tardito,Luciano Marchiò	216
19	Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells 2006 ·Histochemistry and Cell Biology ·Saverio Tardito,Ovidio Bussolati,Francesca Gaccioli,Rita Gatti,Stefano Guizzardi,Jacopo Uggeri,Luciano Marchiò,Maurizio Lanfranchi,R. Franchi‐Gazzola	50
20	Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes 2005 ·Journal of Inorganic Biochemistry ·Francesca Gaccioli,R. Franchi‐Gazzola,Maurizio Lanfranchi,Luciano Marchiò,(unknown),María Angela Pellinghelli,Saverio Tardito,Matteo Tegoni	25

About Saverio Tardito

Saverio Tardito is a scholar working on Cancer Research, Biochemistry and Genetics, having authored 37 papers that have together received 3.1k indexed citations. Recurring topics across this work include Cancer, Hypoxia, and Metabolism (14 papers), Metal complexes synthesis and properties (7 papers) and Amino Acid Enzymes and Metabolism (4 papers). The work is most often cited by research in Cancer Research (1.0k citations), Oncology (916 citations) and Genetics (279 citations). Saverio Tardito has collaborated with scholars based in Italy, United Kingdom and Israel. Frequent co-authors include Luciano Marchiò, Eyal Gottlieb, Ovidio Bussolati, R. Franchi‐Gazzola, Tobias Ackermann, Matteo Tegoni, Claudio Mucchino, Irene Bassanetti, G. Vignir Helgason and Karen Dunn. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Nature Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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