Saverio Tardito

5.9k total citations · 2 hit papers
37 papers, 3.1k citations indexed

About

Saverio Tardito is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Saverio Tardito has authored 37 papers receiving a total of 3.1k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 15 papers in Cancer Research and 12 papers in Oncology. Recurrent topics in Saverio Tardito's work include Cancer, Hypoxia, and Metabolism (14 papers), Metal complexes synthesis and properties (7 papers) and Amino Acid Enzymes and Metabolism (4 papers). Saverio Tardito is often cited by papers focused on Cancer, Hypoxia, and Metabolism (14 papers), Metal complexes synthesis and properties (7 papers) and Amino Acid Enzymes and Metabolism (4 papers). Saverio Tardito collaborates with scholars based in Italy, United Kingdom and Israel. Saverio Tardito's co-authors include Luciano Marchiò, Eyal Gottlieb, Ovidio Bussolati, R. Franchi‐Gazzola, Tobias Ackermann, Matteo Tegoni, Claudio Mucchino, Irene Bassanetti, G. Vignir Helgason and Karen Dunn and has published in prestigious journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Nature Medicine.

In The Last Decade

Saverio Tardito

37 papers receiving 3.0k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

2015 426 citations Saverio Tardito, Eyal Gottlieb et al. profile →
Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

2017 376 citations Alison M. Michie, Karen Dunn et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Saverio Tardito Italy	24	1.6k	1.0k	916	413	279	37	3.1k
Stephen Gately United States	24	2.0k 1.3×	1.2k 1.2×	675 0.7×	373 0.9×	204 0.7×	40	3.5k
Sylvie M. Guichard United Kingdom	33	2.3k 1.5×	445 0.4×	1.6k 1.7×	555 1.3×	243 0.9×	96	4.0k
Athanasios Yiotakis Greece	34	1.7k 1.1×	857 0.8×	1.3k 1.4×	1.1k 2.7×	188 0.7×	74	3.1k
Yunfei Zhou China	29	2.3k 1.5×	1.1k 1.1×	1.1k 1.2×	307 0.7×	97 0.3×	64	4.0k
Dimitris Georgiadis Greece	31	1.2k 0.8×	370 0.4×	893 1.0×	697 1.7×	123 0.4×	65	2.3k
Aurelio Lorico United States	30	1.7k 1.1×	724 0.7×	1.2k 1.3×	138 0.3×	196 0.7×	82	2.8k
Judith Michels France	21	2.5k 1.6×	966 0.9×	2.0k 2.2×	391 0.9×	69 0.2×	55	4.7k
Dong‐Hua Yang United States	41	3.2k 2.1×	813 0.8×	2.1k 2.3×	421 1.0×	153 0.5×	184	5.8k
Yumin Hu China	33	2.4k 1.5×	1.2k 1.1×	630 0.7×	560 1.4×	68 0.2×	76	3.8k
Anthony Tumber United Kingdom	32	2.9k 1.8×	676 0.7×	584 0.6×	340 0.8×	82 0.3×	95	3.6k

Countries citing papers authored by Saverio Tardito

Since Specialization

Citations

This map shows the geographic impact of Saverio Tardito's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Saverio Tardito with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Saverio Tardito more than expected).

Fields of papers citing papers by Saverio Tardito

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Saverio Tardito. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Saverio Tardito. The network helps show where Saverio Tardito may publish in the future.

Co-authorship network of co-authors of Saverio Tardito

This figure shows the co-authorship network connecting the top 25 collaborators of Saverio Tardito. A scholar is included among the top collaborators of Saverio Tardito based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Saverio Tardito. Saverio Tardito is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Ackermann, Tobias, Engy Shokry, Laura C.A. Galbraith, et al.. (2024). Breast cancer secretes anti-ferroptotic MUFAs and depends on selenoprotein synthesis for metastasis. EMBO Molecular Medicine. 16(11). 2749–2774. 7 indexed citations

Kalkman, Eric R., Joe M. Jones, Daniel James, et al.. (2024). Nutrient-sensitizing drug repurposing screen identifies lomerizine as a mitochondrial metabolism inhibitor of chronic myeloid leukemia. Science Translational Medicine. 16(751). eadi5336–eadi5336. 3 indexed citations

Kalkman, Eric R., Mary T. Scott, Karen Dunn, et al.. (2023). Pyruvate anaplerosis is a targetable vulnerability in persistent leukaemic stem cells. Nature Communications. 14(1). 4634–4634. 13 indexed citations

Kalkman, Eric R., Mary T. Scott, Karen Dunn, et al.. (2023). Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells. EMBO Reports. 24(10). e56279–e56279. 5 indexed citations

Charnock‐Jones, D. Stephen, et al.. (2023). Physiologically relevant culture medium Plasmax improves human placental trophoblast stem cell function. American Journal of Physiology-Cell Physiology. 324(4). C878–C885. 2 indexed citations

Pontarin, Giovanna, Matteo Astone, Liaisan Arslanbaeva, et al.. (2022). Aspartate metabolism in endothelial cells activates the mTORC1 pathway to initiate translation during angiogenesis. Developmental Cell. 57(10). 1241–1256.e8. 29 indexed citations

Chiu, Martina, Giuseppe Taurino, Erica Dander, et al.. (2021). ALL blasts drive primary mesenchymal stromal cells to increase asparagine availability during asparaginase treatment. Blood Advances. 5(23). 5164–5178. 23 indexed citations

Allega, Maria Francesca, et al.. (2021). A map of the altered glioma metabolism. Trends in Molecular Medicine. 27(11). 1045–1059. 36 indexed citations

Voorde, Johan Vande, Tobias Ackermann, David Sumpton, et al.. (2019). Improving the metabolic fidelity of cancer models with a physiological cell culture medium. Science Advances. 5(1). eaau7314–eaau7314. 235 indexed citations

10.

Clerc, Isabelle, Saverio Tardito, Leal Oburoglu, et al.. (2019). Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells. Nature Metabolism. 1(7). 717–730. 67 indexed citations

11.

Chiu, Martina, Saverio Tardito, Serena Pillozzi, et al.. (2014). Glutamine depletion by crisantaspase hinders the growth of human hepatocellular carcinoma xenografts. British Journal of Cancer. 111(6). 1159–1167. 63 indexed citations

12.

Rizzi, Federica, Valeria Naponelli, Ileana Ramazzina, et al.. (2013). Polyphenon E®, a standardized green tea extract, induces endoplasmic reticulum stress, leading to death of immortalized PNT1a cells by anoikis and tumorigenic PC3 by necroptosis. Carcinogenesis. 35(4). 828–839. 51 indexed citations

13.

Tardito, Saverio, Amelia Barilli, Irene Bassanetti, et al.. (2012). Copper-Dependent Cytotoxicity of 8-Hydroxyquinoline Derivatives Correlates with Their Hydrophobicity and Does Not Require Caspase Activation. Journal of Medicinal Chemistry. 55(23). 10448–10459. 193 indexed citations

14.

Durán, Raúl V., Elaine D. MacKenzie, Houda Boulahbel, et al.. (2012). HIF-independent role of prolyl hydroxylases in the cellular response to amino acids. Oncogene. 32(38). 4549–4556. 103 indexed citations

15.

Tardito, Saverio, Martina Chiu, Jacopo Uggeri, et al.. (2011). L-Asparaginase and Inhibitors of Glutamine Synthetase Disclose Glutamine Addiction of β-Catenin-Mutated Human Hepatocellular Carcinoma Cells. Current Cancer Drug Targets. 11(8). 929–943. 43 indexed citations

16.

Tardito, Saverio, et al.. (2011). Expanding Targets for a Metabolic Therapy of Cancer: L-Asparaginase. Recent Patents on Anti-Cancer Drug Discovery. 7(1). 4–13. 94 indexed citations

17.

Tardito, Saverio, Martina Chiu, R. Franchi‐Gazzola, et al.. (2011). The non-proteinogenic amino acids l-methionine sulfoximine and dl-phosphinothricin activate mTOR. Amino Acids. 42(6). 2507–2512. 9 indexed citations

18.

Tardito, Saverio & Luciano Marchiò. (2009). Copper Compounds in Anticancer Strategies. Current Medicinal Chemistry. 16(11). 1325–1348. 216 indexed citations

19.

Tardito, Saverio, Ovidio Bussolati, Francesca Gaccioli, et al.. (2006). Non-apoptotic programmed cell death induced by a copper(II) complex in human fibrosarcoma cells. Histochemistry and Cell Biology. 126(4). 473–482. 50 indexed citations

20.

Gaccioli, Francesca, R. Franchi‐Gazzola, Maurizio Lanfranchi, et al.. (2005). Synthesis, solution equilibria and antiproliferative activity of copper(II) aminomethyltriazole and aminomethylthioxotriazoline complexes. Journal of Inorganic Biochemistry. 99(8). 1573–1584. 25 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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