Michael Desch

621 total citations
20 papers, 503 citations indexed

About

Michael Desch is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Endocrinology, Diabetes and Metabolism. According to data from OpenAlex, Michael Desch has authored 20 papers receiving a total of 503 indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Molecular Biology, 7 papers in Cellular and Molecular Neuroscience and 5 papers in Endocrinology, Diabetes and Metabolism. Recurrent topics in Michael Desch's work include Receptor Mechanisms and Signaling (11 papers), Drug Transport and Resistance Mechanisms (4 papers) and Pharmacological Effects and Toxicity Studies (4 papers). Michael Desch is often cited by papers focused on Receptor Mechanisms and Signaling (11 papers), Drug Transport and Resistance Mechanisms (4 papers) and Pharmacological Effects and Toxicity Studies (4 papers). Michael Desch collaborates with scholars based in Germany, United States and Canada. Michael Desch's co-authors include Vladimir Todorov, Glen Wunderlich, Holger Rosenbrock, Armin Kurtz, Frank Schweda, Sven Wind, Karl‐Heinz Liesenfeld, Viktoria Moschetti, Thomas Schubert and Hayo Castrop and has published in prestigious journals such as Journal of Biological Chemistry, Endocrinology and Hypertension.

In The Last Decade

Michael Desch

18 papers receiving 498 citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Michael Desch Germany	13	255	121	120	120	107	20	503
Marı́a A. Garcı́a-Espinosa United States	13	227 0.9×	91 0.8×	183 1.5×	26 0.2×	189 1.8×	19	600
Patrizia Angelico Italy	15	210 0.8×	102 0.8×	196 1.6×	74 0.6×	88 0.8×	27	620
Roger Løvlie Norway	12	317 1.2×	49 0.4×	214 1.8×	308 2.6×	23 0.2×	14	950
Peter Bond United Kingdom	10	169 0.7×	117 1.0×	69 0.6×	40 0.3×	18 0.2×	17	465
Gordana Župan Croatia	13	156 0.6×	29 0.2×	194 1.6×	149 1.2×	31 0.3×	36	559
Sean Ross United States	8	284 1.1×	63 0.5×	170 1.4×	26 0.2×	69 0.6×	10	520
Michael E. Brune United States	18	251 1.0×	155 1.3×	83 0.7×	17 0.1×	33 0.3×	41	746
R. Klysner Denmark	14	198 0.8×	34 0.3×	153 1.3×	232 1.9×	47 0.4×	38	670
Kathryn W. Schenck United States	13	314 1.2×	28 0.2×	238 2.0×	86 0.7×	114 1.1×	25	672
Zidonia N. Carneiro United States	13	199 0.8×	200 1.7×	44 0.4×	179 1.5×	89 0.8×	19	564

Countries citing papers authored by Michael Desch

Since Specialization

Citations

This map shows the geographic impact of Michael Desch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Desch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Desch more than expected).

Fields of papers citing papers by Michael Desch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Desch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Desch. The network helps show where Michael Desch may publish in the future.

Co-authorship network of co-authors of Michael Desch

This figure shows the co-authorship network connecting the top 25 collaborators of Michael Desch. A scholar is included among the top collaborators of Michael Desch based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael Desch. Michael Desch is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Desch, Michael, et al.. (2025). Evaluation of the Drug–Drug Interaction Potential of the GlyT1 Inhibitor Iclepertin (BI 425809): A Physiologically Based Pharmacokinetic (PBPK) Modeling Approach. CPT Pharmacometrics & Systems Pharmacology. 14(8). 1391–1402.

Rosenbrock, Holger, Michael Desch, & Glen Wunderlich. (2023). Development of the novel GlyT1 inhibitor, iclepertin (BI 425809), for the treatment of cognitive impairment associated with schizophrenia. European Archives of Psychiatry and Clinical Neuroscience. 273(7). 1557–1566. 49 indexed citations

Desch, Michael, Christina Schlecker, Kathrin Hohl, et al.. (2023). Pharmacokinetic-Interactions of BI 425809, a Novel Glycine Transporter 1 Inhibitor, With Cytochrome P450 and P-Glycoprotein Substrates. Journal of Clinical Psychopharmacology. 43(2). 113–121. 2 indexed citations

Jungnik, Arvid, Jorge Arrubla, Leona Plum‐Mörschel, et al.. (2022). Phase I studies of the safety, tolerability, pharmacokinetics and pharmacodynamics of the dual glucagon receptor/glucagon‐like peptide‐1 receptor agonist BI 456906. Diabetes Obesity and Metabolism. 25(4). 1011–1023. 48 indexed citations

Desch, Michael, et al.. (2022). Safety, tolerability and pharmacokinetics of single rising doses of BI 1569912 in healthy males – a Phase I study. Neuroscience Applied. 1. 100804–100804.

Fleischhacker, W. Wolfgang, Jana Podhorná, Yihua Zhao, et al.. (2021). Efficacy and safety of the novel glycine transporter inhibitor BI 425809 once daily in patients with schizophrenia: a double-blind, randomised, placebo-controlled phase 2 study. The Lancet Psychiatry. 8(3). 191–201. 96 indexed citations

Desch, Michael, Glen Wunderlich, Karl‐Heinz Liesenfeld, et al.. (2021). Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor. European Journal of Drug Metabolism and Pharmacokinetics. 47(1). 91–103. 6 indexed citations

Desch, Michael, et al.. (2021). The Absolute Bioavailability, Absorption, Distribution, Metabolism, and Excretion of BI 425809 Administered as an Oral Dose or an Oral Dose with an Intravenous Microtracer Dose of [14C]-BI 425809 in Healthy Males. Clinical Drug Investigation. 42(1). 87–99. 3 indexed citations

Moschetti, Viktoria, Christina Schlecker, Sven Wind, et al.. (2018). Multiple Rising Doses of Oral BI 425809, a GlyT1 Inhibitor, in Young and Elderly Healthy Volunteers: A Randomised, Double-Blind, Phase I Study Investigating Safety and Pharmacokinetics. Clinical Drug Investigation. 38(8). 737–750. 26 indexed citations

10.

Rosenbrock, Holger, Michael Desch, Oliver Kleiner, et al.. (2018). Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies. Clinical and Translational Science. 11(6). 616–623. 33 indexed citations

11.

Moschetti, Viktoria, Michael Desch, Karl‐Heinz Liesenfeld, et al.. (2017). Safety, Tolerability and Pharmacokinetics of Oral BI 425809, a Glycine Transporter 1 Inhibitor, in Healthy Male Volunteers: A Partially Randomised, Single-Blind, Placebo-Controlled, First-in-Human Study. European Journal of Drug Metabolism and Pharmacokinetics. 43(2). 239–249. 28 indexed citations

12.

Lachmann, Peter J., Jae Mi Suh, Sabine Harlander, et al.. (2012). Chicken Ovalbumin Upstream Promoter Transcription Factor II Regulates Renin Gene Expression. Journal of Biological Chemistry. 287(29). 24483–24491. 6 indexed citations

13.

Desch, Michael, Sabine Harlander, Björn Neubauer, et al.. (2011). cAMP target sequences enhCRE and CNRE sense low-salt intake to increase human renin gene expression in vivo. Pflügers Archiv - European Journal of Physiology. 461(5). 567–577. 14 indexed citations

14.

Desch, Michael, et al.. (2011). Identification of ATF2 as a transcriptional regulator of renin gene. Biological Chemistry. 393(1-2). 93–100. 7 indexed citations

15.

Desch, Michael, Thomas Schubert, Andrea Schreiber, et al.. (2010). PPARγ-Dependent Regulation of Adenylate Cyclase 6 Amplifies the Stimulatory Effect of cAMP on Renin Gene Expression. Molecular Endocrinology. 24(11). 2139–2151. 14 indexed citations

16.

Desch, Michael, Andrea Schreiber, Frank Schweda, et al.. (2010). Increased Renin Production in Mice With Deletion of Peroxisome Proliferator-Activated Receptor-γ in Juxtaglomerular Cells. Hypertension. 55(3). 660–666. 22 indexed citations

17.

Milenkovic, Vladimir M., Marisa M. Brockmann, Christian Meyer, et al.. (2010). Regulation of the renin expression in the retinal pigment epithelium by systemic stimuli. American Journal of Physiology-Renal Physiology. 299(2). F396–F403. 30 indexed citations

18.

Todorov, Vladimir, Michael Desch, Thomas Schubert, & Armin Kurtz. (2008). The Pal3 Promoter Sequence Is Critical for the Regulation of Human Renin Gene Transcription by Peroxisome Proliferator-Activated Receptor-γ. Endocrinology. 149(9). 4647–4657. 22 indexed citations

19.

Hautmann, Matthias, Ulla G. Friis, Michael Desch, et al.. (2007). Pituitary Adenylate Cyclase–Activating Polypeptide Stimulates Renin Secretion via Activation of PAC1 Receptors. Journal of the American Society of Nephrology. 18(4). 1150–1156. 41 indexed citations

20.

Todorov, Vladimir, et al.. (2007). Peroxisome Proliferator-Activated Receptor-γ Is Involved in the Control of Renin Gene Expression. Hypertension. 50(5). 939–944. 56 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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