Michael Desch

621 citations

20 papers · 503 indexed · h-index 13

Impact in

Biological Psychiatry top 10%
- Tryptophan and brain disorders
Psychiatry and Mental health top 10%
- Schizophrenia research and treatment

Papers in ⓘ

Molecular Biology 13
- Receptor Mechanisms and Signaling 11
- Peroxisome Proliferator-Activated Receptors 4
Cellular and Molecular Neuroscience 7
- Neuropeptides and Animal Physiology 3

Co-authors: Vladimir Todorov (9 shared papers)Glen Wunderlich (7 shared papers)Holger Rosenbrock (4 shared papers)Armin Kurtz (2 shared papers)Frank Schweda (3 shared papers)Viktoria Moschetti (3 shared papers)Sven Wind (5 shared papers)Karl‐Heinz Liesenfeld (5 shared papers)
Journals: Hypertension (2 papers)Endocrinology (1 paper)Biological Chemistry (1 paper)The Lancet Psychiatry (1 paper)Clinical and Translational Science (1 paper)
Partner nations: Germany United States Canada

In The Last Decade

Michael Desch

18 papers receiving 498 citations

Peers

Countries citing papers authored by Michael Desch

Since Specialization

Citations

This map shows the geographic impact of Michael Desch's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Desch with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Desch more than expected).

Fields of papers citing papers by Michael Desch

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Desch. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Desch. The network helps show where Michael Desch may publish in the future.

Co-authors

The 25 scholars most cited alongside Michael Desch, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Michael Desch Line = papers co-authored together Michael Desch links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Efficacy and safety of the novel glycine transporter inhibitor BI 425809 once daily in patients with schizophrenia: a double-blind, randomised, placebo-controlled phase 2 study The Lancet Psychiatry ·W. Wolfgang Fleischhacker, Jana Podhorná, Martina Gröschl, Sanjay Hake, Yihua Zhao, Songqiao Huang, Richard S.E. Keefe, Michael Desch, Ronald Brenner, David P. Walling, E. Mantero-Atienza, Kazuyuki Nakagome, Stephane Pollentier	2021	96
2	Peroxisome Proliferator-Activated Receptor-γ Is Involved in the Control of Renin Gene Expression Hypertension ·Vladimir Todorov, Michael Desch, Nina Schmitt-Nilson, Anelia Todorova, Armin Kurtz	2007	56
3	Development of the novel GlyT1 inhibitor, iclepertin (BI 425809), for the treatment of cognitive impairment associated with schizophrenia European Archives of Psychiatry and Clinical Neuroscience ·Holger Rosenbrock, Michael Desch, Glen Wunderlich	2023	49
4	Phase I studies of the safety, tolerability, pharmacokinetics and pharmacodynamics of the dual glucagon receptor/glucagon‐like peptide‐1 receptor agonist BI 456906 Diabetes Obesity and Metabolism ·Arvid Jungnik, Jorge Arrubla, Leona Plum‐Mörschel, Christoph Kapitza, Daniela Lamers, Claus Thamer, Corinna Schölch, Michael Desch, Anita M. Hennige	2022	48
5	Pituitary Adenylate Cyclase–Activating Polypeptide Stimulates Renin Secretion via Activation of PAC1 Receptors Journal of the American Society of Nephrology ·Matthias Hautmann, Ulla G. Friis, Michael Desch, Vladimir Todorov, Hayo Castrop, Florian Segerer, Christiane Otto, GuCombining Diaeresisnther SchuCombining Diaeresistz, Frank Schweda	2007	41
6	Evaluation of Pharmacokinetics and Pharmacodynamics of BI 425809, a Novel GlyT1 Inhibitor: Translational Studies Clinical and Translational Science ·Holger Rosenbrock, Michael Desch, Oliver Kleiner, Cornelia Dorner‐Ciossek, Hans Bernhard Schmid, Sascha Keller, Christina Schlecker, Viktoria Moschetti, Sophia Goetz, Karl‐Heinz Liesenfeld, Gwenaëlle Fillon, Riccardo Giovannini, Steven Ramael, Glen Wunderlich, Sven Wind	2018	33
7	Regulation of the renin expression in the retinal pigment epithelium by systemic stimuli American Journal of Physiology-Renal Physiology ·Vladimir M. Milenkovic, Marisa M. Brockmann, Christian Meyer, Michael Desch, Frank Schweda, Armin Kurtz, Vladimir Todorov, Olaf Strauß	2010	30
8	Safety, Tolerability and Pharmacokinetics of Oral BI 425809, a Glycine Transporter 1 Inhibitor, in Healthy Male Volunteers: A Partially Randomised, Single-Blind, Placebo-Controlled, First-in-Human Study European Journal of Drug Metabolism and Pharmacokinetics ·Viktoria Moschetti, Michael Desch, Sophia Goetz, Karl‐Heinz Liesenfeld, Holger Rosenbrock, Klaus-Peter Kammerer, Glen Wunderlich, Sven Wind	2017	28
9	Multiple Rising Doses of Oral BI 425809, a GlyT1 Inhibitor, in Young and Elderly Healthy Volunteers: A Randomised, Double-Blind, Phase I Study Investigating Safety and Pharmacokinetics Clinical Drug Investigation ·Viktoria Moschetti, Christina Schlecker, Sven Wind, Sophia Goetz, H. Schmitt, Armin Schultz, Karl‐Heinz Liesenfeld, Glen Wunderlich, Michael Desch	2018	26
10	Increased Renin Production in Mice With Deletion of Peroxisome Proliferator-Activated Receptor-γ in Juxtaglomerular Cells Hypertension ·Michael Desch, Andrea Schreiber, Frank Schweda, Kirsten Madsen, Ulla G. Friis, Eric T. Weatherford, Curt D. Sigmund, Maria Luisa S. Sequeira-Lόpez, R. Ariel Gómez, Vladimir Todorov	2010	22
11	The Pal3 Promoter Sequence Is Critical for the Regulation of Human Renin Gene Transcription by Peroxisome Proliferator-Activated Receptor-γ Endocrinology ·Vladimir Todorov, Michael Desch, Thomas Schubert, Armin Kurtz	2008	22
12	cAMP target sequences enhCRE and CNRE sense low-salt intake to increase human renin gene expression in vivo Pflügers Archiv - European Journal of Physiology ·Michael Desch, Sabine Harlander, Björn Neubauer, Melanie Gerl, Stéphane Germain, Hayo Castrop, Vladimir Todorov	2011	14
13	PPARγ-Dependent Regulation of Adenylate Cyclase 6 Amplifies the Stimulatory Effect of cAMP on Renin Gene Expression Molecular Endocrinology ·Michael Desch, Thomas Schubert, Andrea Schreiber, Sandra M. Mayer, Björn Friedrich, Ferruh Artunç, Vladimir Todorov	2010	14
14	Identification of ATF2 as a transcriptional regulator of renin gene Biological Chemistry ·Michael Desch, Gerit Hackmayer, Vladimir Todorov	2011	7
15	Effects of Cytochrome P450 3A4 Induction and Inhibition on the Pharmacokinetics of BI 425809, a Novel Glycine Transporter 1 Inhibitor European Journal of Drug Metabolism and Pharmacokinetics ·Michael Desch, Glen Wunderlich, Markus Goettel, Sophia Goetz, Karl‐Heinz Liesenfeld, Tom S. Chan, Holger Rosenbrock, Regina Sennewald, Jasmin Link, Sascha Keller, Sven Wind	2021	6
16	Chicken Ovalbumin Upstream Promoter Transcription Factor II Regulates Renin Gene Expression Journal of Biological Chemistry ·Sandra M. Mayer, Marc Roeser, Peter J. Lachmann, Sumiyashi Ishii, Jae Mi Suh, Sabine Harlander, Michael Desch, Coy Brunßen, Henning Morawietz, Sophia Y. Tsai, Ming‐Jer Tsai, Bernd Hohenstein, Christian Hugo, Vladimir Todorov	2012	6
17	The Absolute Bioavailability, Absorption, Distribution, Metabolism, and Excretion of BI 425809 Administered as an Oral Dose or an Oral Dose with an Intravenous Microtracer Dose of [14C]-BI 425809 in Healthy Males Clinical Drug Investigation ·Ute Burkard, Michael Desch, Yury Shatillo, Glen Wunderlich, Salome Rebecca Mack, Christina Schlecker, Aaron M. Teitelbaum, Pingrong Liu, Tom S. Chan	2021	3
18	Pharmacokinetic-Interactions of BI 425809, a Novel Glycine Transporter 1 Inhibitor, With Cytochrome P450 and P-Glycoprotein Substrates Journal of Clinical Psychopharmacology ·Michael Desch, Christina Schlecker, Kathrin Hohl, Karl‐Heinz Liesenfeld, Tom S. Chan, Fabian Müller, Glen Wunderlich, Sascha Keller, Naoki Ishiguro, Sven Wind	2023	2
19	Evaluation of the Drug–Drug Interaction Potential of the GlyT1 Inhibitor Iclepertin (BI 425809): A Physiologically Based Pharmacokinetic (PBPK) Modeling Approach CPT Pharmacometrics & Systems Pharmacology ·Elin M. Matsson, Michael Desch, Valerie Nock, Nina Hanke	2025	0
20	Safety, tolerability and pharmacokinetics of single rising doses of BI 1569912 in healthy males – a Phase I study Neuroscience Applied ·Michael Desch, Andreas Huennemeyer, S. Suessmuth	2022	0

About Michael Desch

Michael Desch is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Endocrinology, Diabetes and Metabolism, Cardiology and Cardiovascular Medicine and Pediatrics, Perinatology and Child Health, having authored 20 papers that have together received 503 indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (11 papers), Pharmacological Effects and Toxicity Studies (4 papers), Peroxisome Proliferator-Activated Receptors (4 papers), Renin-Angiotensin System Studies (4 papers), Drug Transport and Resistance Mechanisms (4 papers), Neuropeptides and Animal Physiology (3 papers), Pharmacogenetics and Drug Metabolism (3 papers) and Hormonal Regulation and Hypertension (3 papers). The work is most often cited by research in Biological Psychiatry (52 citations), Psychiatry and Mental health (120 citations), Biochemistry (56 citations), Endocrinology, Diabetes and Metabolism (121 citations) and Cellular and Molecular Neuroscience (120 citations). Michael Desch has collaborated with scholars based in Germany, United States and Canada. Frequent co-authors include Vladimir Todorov, Glen Wunderlich, Holger Rosenbrock, Armin Kurtz, Frank Schweda, Viktoria Moschetti, Sven Wind, Karl‐Heinz Liesenfeld, Thomas Schubert and Hayo Castrop. Their work appears in journals such as Hypertension, Endocrinology, Biological Chemistry, The Lancet Psychiatry and Clinical and Translational Science.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact