Massimo Negrini

56.2k total citations · 14 hit papers
262 papers, 40.0k citations indexed

About

Massimo Negrini is a scholar working on Molecular Biology, Cancer Research and Oncology. According to data from OpenAlex, Massimo Negrini has authored 262 papers receiving a total of 40.0k indexed citations (citations by other indexed papers that have themselves been cited), including 171 papers in Molecular Biology, 119 papers in Cancer Research and 50 papers in Oncology. Recurrent topics in Massimo Negrini's work include MicroRNA in disease regulation (95 papers), Cancer-related molecular mechanisms research (57 papers) and Circular RNAs in diseases (49 papers). Massimo Negrini is often cited by papers focused on MicroRNA in disease regulation (95 papers), Cancer-related molecular mechanisms research (57 papers) and Circular RNAs in diseases (49 papers). Massimo Negrini collaborates with scholars based in Italy, United States and United Kingdom. Massimo Negrini's co-authors include Carlo M. Croce, George A. Calin, Manuela Ferracin, Masayoshi Shimizu, Chang‐Gong Liu, Silvia Sabbioni, Florencia Bullrich, Stefano Volinia, Calin Dan Dumitru and Angelo Veronese and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Massimo Negrini

256 papers receiving 39.2k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A microRNA expression signature of human solid tumors defines cancer gene targets

2006 4.7k citations Stefano Volinia, George A. Calin et al. Proceedings of the National Academy of Sciences profile →
Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia

2002 3.9k citations George A. Calin, Calin Dan Dumitru et al. Proceedings of the National Academy of Sciences profile →
MicroRNA Gene Expression Deregulation in Human Breast Cancer

2005 3.3k citations Marilena V. Iorio, Manuela Ferracin et al. Cancer Research profile →
Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers

2004 3.3k citations George A. Calin, Cinzia Sevignani et al. Proceedings of the National Academy of Sciences profile →
miR-15 and miR-16 induce apoptosis by targeting BCL2

2005 2.8k citations Amelia Cimmino, George A. Calin et al. Proceedings of the National Academy of Sciences profile →
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias

2004 1.0k citations George A. Calin, Chang‐Gong Liu et al. Proceedings of the National Academy of Sciences profile →
A MicroRNA Signature of Hypoxia

2006 890 citations Manuela Ferracin, Sylwia E. Wojcik et al. profile →
Extensive modulation of a set of microRNAs in primary glioblastoma

2005 887 citations Manuela Ferracin, Massimo Negrini et al. profile →
An oligonucleotide microchip for genome-wide microRNA profiling in human and mouse tissues

2004 754 citations Chang‐Gong Liu, George A. Calin et al. Proceedings of the National Academy of Sciences profile →
E2F1-Regulated MicroRNAs Impair TGFβ-Dependent Cell-Cycle Arrest and Apoptosis in Gastric Cancer

2008 719 citations Fabio Petrocca, Rosa Visone et al. profile →
Cyclin G1 Is a Target of miR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma

2007 670 citations Laura Gramantieri, Manuela Ferracin et al. Cancer Research profile →
MiR-15a and miR-16-1 cluster functions in human leukemia

2008 607 citations George A. Calin, Amelia Cimmino et al. Proceedings of the National Academy of Sciences profile →
microRNA-29 can regulate expression of the long non-coding RNA gene MEG3 in hepatocellular cancer

2011 545 citations Massimo Negrini et al. profile →
MiR-221 controls CDKN1C/p57 and CDKN1B/p27 expression in human hepatocellular carcinoma

2008 517 citations Francesca Fornari, Laura Gramantieri et al. profile →

Peers

Countries citing papers authored by Massimo Negrini

Since Specialization

Citations

This map shows the geographic impact of Massimo Negrini's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Massimo Negrini with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Massimo Negrini more than expected).

Fields of papers citing papers by Massimo Negrini

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Massimo Negrini. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Massimo Negrini. The network helps show where Massimo Negrini may publish in the future.

Co-authorship network of co-authors of Massimo Negrini

This figure shows the co-authorship network connecting the top 25 collaborators of Massimo Negrini. A scholar is included among the top collaborators of Massimo Negrini based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Massimo Negrini. Massimo Negrini is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Near-Complete Response to Osimertinib for Advanced Non-Small-Cell Lung Cancer in a Pretreated Patient Bearing Rare Compound Exon 20 Mutation (S768I + V774M): A Case Report 2024 ·International Journal of Molecular Sciences ·(unknown), (unknown), Chiara Magri, Aldo Carnevale, Antonella Ciancetta, Massimo Guidoboni, Massimo Negrini, Giuseppe Bronte, Luana Calabrò	0
2	Circulating CD8 lymphocytes predict response to atezolizumab–bevacizumab in hepatocellular carcinoma 2023 ·European Journal of Immunology ·Laura Gramantieri, (unknown), Cristian Bassi, Lucilla D’Abundo, Francesco Tovoli, (unknown), (unknown), (unknown), Francesca Fornari, Massimo Negrini, Massimo Iavarone, Fabio Piscaglia, Catia Giovannini	5
3	Gene Expression Landscape of Chronic Myeloid Leukemia K562 Cells Overexpressing the Tumor Suppressor Gene PTPRG 2022 ·International Journal of Molecular Sciences ·(unknown), (unknown), Alessandro Mosca, Diego Calvanese, Luisa Tomasello, (unknown), Manuela Ferracin, Massimo Negrini, Nader Al‐Dewik, Mohamed A. Yassin, Mohamed A. Ismail, Bruno Carpentieri, Claudio Sorio, Paola Lecca	4
4	MiR-30e-3p Influences Tumor Phenotype through MDM2 / TP53 Axis and Predicts Sorafenib Resistance in Hepatocellular Carcinoma 2020 ·Cancer Research ·Laura Gramantieri, Daniela Pollutri, Martina Gagliardi, Catia Giovannini, Santina Quarta, Manuela Ferracin, Andrea Casadei‐Gardini, Elisa Callegari, Sabrina De Carolis, Sara Marinelli, Francesca Benevento, Francesco Vasuri, Matteo Ravaioli, Matteo Cescon, Fabio Piscaglia, Massimo Negrini, Luigi Bolondi, Francesca Fornari	50
5	In Hepatocellular Carcinoma miR-221 Modulates Sorafenib Resistance through Inhibition of Caspase-3–Mediated Apoptosis 2017 ·Clinical Cancer Research ·Francesca Fornari, Daniela Pollutri, Clarissa Patrizi, Tiziana La Bella, Sara Marinelli, Andrea Casadei‐Gardini, Giorgia Marisi, Marco Baron Toaldo, Michele Baglioni, Veronica Salvatore, Elisa Callegari, Maurizio Baldassarre, Marzia Galassi, Catia Giovannini, Matteo Cescon, Matteo Ravaioli, Massimo Negrini, Luigi Bolondi, Laura Gramantieri	137
6	Quantification of Circulating miRNAs by Droplet Digital PCR: Comparison of EvaGreen- and TaqMan-Based Chemistries 2014 ·Cancer Epidemiology Biomarkers & Prevention ·Elena Miotto, Elena Saccenti, Laura Lupini, Elisa Callegari, Massimo Negrini, Manuela Ferracin	74
7	Oncogenic Role of miR-483-3p at the IGF2/483 Locus 2010 ·Cancer Research ·Angelo Veronese, Laura Lupini, Jessica Consiglio, Rosa Visone, Manuela Ferracin, Francesca Fornari, Nicola Zanesi, Hansjüerg Alder, Gemma D’Elia, Laura Gramantieri, Luigi Bolondi, Giovanni Lanza, Patrizia Querzoli, Adriano Angioni, Carlo M. Croce, Massimo Negrini	182
8	MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells 2010 ·Cancer Research ·Francesca Fornari, Maddalena Milazzo, Pasquale Chieco, Massimo Negrini, George A. Calin, Gian Luca Grazi, Daniela Pollutri, Carlo M. Croce, Luigi Bolondi, Laura Gramantieri	343
9	MicroRNA-221 Targets Bmf in Hepatocellular Carcinoma and Correlates with Tumor Multifocality 2009 ·Clinical Cancer Research ·Laura Gramantieri, Francesca Fornari, Manuela Ferracin, Angelo Veronese, Silvia Sabbioni, George A. Calin, Gian Luca Grazi, Carlo M. Croce, Luigi Bolondi, Massimo Negrini	261
10	MiR-122/Cyclin G1 Interaction Modulates p53 Activity and Affects Doxorubicin Sensitivity of Human Hepatocarcinoma Cells 2009 ·Cancer Research ·Francesca Fornari, Laura Gramantieri, Catia Giovannini, Angelo Veronese, Manuela Ferracin, Silvia Sabbioni, George A. Calin, Gian Luca Grazi, Carlo M. Croce, Simona Tavolari, Pasquale Chieco, Massimo Negrini, Luigi Bolondi	343
11	Cyclin G1 Is a Target of miR-122a, a MicroRNA Frequently Down-regulated in Human Hepatocellular Carcinoma breakdown → 2007 ·Cancer Research ·Laura Gramantieri, Manuela Ferracin, Francesca Fornari, Angelo Veronese, Silvia Sabbioni, Chang‐Gong Liu, George A. Calin, Catia Giovannini, Eros Ferrazzí, Gian Luca Grazi, Carlo M. Croce, Luigi Bolondi, Massimo Negrini	670
12	Tumor Suppressor Functions of ARLTS1 in Lung Cancers 2007 ·Cancer Research ·Sai Yendamuri, Francesco Trapasso, Manuela Ferracin, Rossano Cesari, Cinzia Sevignani, Masayoshi Shimizu, Shashi Rattan, Tamotsu Kuroki, Kristoffel R. Dumon, Florencia Bullrich, Chang‐Gong Liu, Massimo Negrini, Noel N. Williams, Larry R. Kaiser, Carlo M. Croce, George A. Calin	13
13	A microRNA expression signature of human solid tumors defines cancer gene targets breakdown → 2006 ·Proceedings of the National Academy of Sciences ·Stefano Volinia, George A. Calin, Chang‐Gong Liu, Stefan Ambs, Amelia Cimmino, Fabio Petrocca, Rosa Visone, Marilena V. Iorio, Claudia Roldo, Manuela Ferracin, Robyn L. Prueitt, (unknown), Giovanni Lanza, Aldo Scarpa, Andrea Vecchione, Massimo Negrini, Curtis C. Harris, Carlo M. Croce	4730
14	Alterations of the Tumor Suppressor Gene ARLTS1 in Ovarian Cancer 2006 ·Cancer Research ·Fabio Petrocca, Dimitrios Iliopoulos, Haiyan Qin, Milena S. Nicoloso, (unknown), Sylwia E. Wojcik, Masayoshi Shimizu, Gianpiero Di Leva, Andrea Vecchione, Francesco Trapasso, Andrew K. Godwin, Massimo Negrini, George A. Calin, Carlo M. Croce	37
15	miR-15 and miR-16 induce apoptosis by targeting BCL2 breakdown → 2005 ·Proceedings of the National Academy of Sciences ·Amelia Cimmino, George A. Calin, Muller Fabbri, Marilena V. Iorio, Manuela Ferracin, Masayoshi Shimizu, Sylwia E. Wojcik, Rami I. Aqeilan, Simona Zupo, Mariella Dono, Laura Z. Rassenti, Hansjüerg Alder, Stefano Volinia, Chang‐Gong Liu, Thomas J. Kipps, Massimo Negrini, Carlo M. Croce	2787
16	MicroRNA Gene Expression Deregulation in Human Breast Cancer breakdown → 2005 ·Cancer Research ·Marilena V. Iorio, Manuela Ferracin, Chang‐Gong Liu, Angelo Veronese, Riccardo Spizzo, Silvia Sabbioni, Eros Magri, Massimo Pedriali, Muller Fabbri, Manuela Campiglio, Sylvie Ménard, Juan Palazzo, Anne Rosenberg, Piero Musiani, Stefano Volinia, Italo Nenci, George A. Calin, Patrizia Querzoli, Massimo Negrini, Carlo M. Croce	3320
17	Frequent Aberrant Methylation of the *CDH4* Gene Promoter in Human Colorectal and Gastric Cancer 2004 ·Cancer Research ·Elena Miotto, Silvia Sabbioni, Angelo Veronese, George A. Calin, S. Gullini, A Liboni, Laura Gramantieri, Luigi Bolondi, Eros Ferrazzí, Roberta Gafà, Giovanni Lanza, Massimo Negrini	81
18	Frequent deletions and down-regulation of micro- RNA genes miR15 and miR16 at 13q14 in chronic lymphocytic leukemia breakdown → 2002 ·Proceedings of the National Academy of Sciences ·George A. Calin, Calin Dan Dumitru, Masayoshi Shimizu, (unknown), Simona Zupo, Evan Noch, (unknown), (unknown), Michael J. Keating, R. Kanti, Laura Z. Rassenti, Thomas J. Kipps, Massimo Negrini, Florencia Bullrich, Carlo M. Croce	3875
19	Structure and expression of the human FHIT gene in normal and tumor cells. 1997 ·PubMed ·Teresa Druck, Piotr Hadaczek, T B Fu, Masataka Ohta, Zurab Siprashvili, Raffaele Baffa, Massimo Negrini, Kumar Kastury, M L Veronese, Daniel Rosen, Jay L. Rothstein, Peter McCue, M. Grazia Cotticelli, Hiroshi Inoué, C M Croce, K Huebner	173
20	Aberrant FHIT transcripts in Merkel cell carcinoma. 1996 ·PubMed ·Gabriella Sozzi, Hansjüerg Alder, (unknown), (unknown), Raffaele Baffa, M L Veronese, Massimo Negrini, S. Pilotti, Marco A. Pierotti, K Huebner, C M Croce	65

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