Bei Shan

11.9k citations

31 papers · 9.0k indexed · 4 hit papers · h-index 25

Impact in

Oncology top 0.5%
- Drug Transport and Resistance Mechanisms
Biochemistry top 0.2%
- Lipid metabolism and biosynthesis

Papers in

Oncology 19
- Drug Transport and Resistance Mechanisms 12
- Cancer-related Molecular Pathways 7
Ophthalmology 5
- Ocular Oncology and Treatments 4

Co-authors: David J. Mangelsdorf Joyce J. Repa Hua Tu Kevin D. Lustig R. Marc Learned Joshua R. Schultz Makoto Makishima Mitchell Hull
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Molecular and Cellular Biology (4 papers)Journal of Biological Chemistry (3 papers)Proceedings of the National Academy of Sciences (3 papers)Genes & Development (2 papers)
Partner nations: United States Japan Netherlands

In The Last Decade

Bei Shan

31 papers receiving 8.7k citations

Hit Papers

align trajectories log scale

Role of LXRs in control of lipogenesis 2000 · 1.4k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2000 Genes & Development
2000 Science
2000 Genes & Development
1999 Science

Peers

Countries citing papers authored by Bei Shan

Since Specialization

Citations

This map shows the geographic impact of Bei Shan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Bei Shan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Bei Shan more than expected).

Fields of papers citing papers by Bei Shan

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Bei Shan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Bei Shan. The network helps show where Bei Shan may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Bei Shan, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Bei Shan Line = papers co-authored together Bei Shan links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Advancing therapeutic discovery through phenotypic screening of the extracellular proteome using hydrodynamic intravascular injection Expert Opinion on Therapeutic Targets ·Hélène Baribault, L. Senf, Hongfei Ge, Jinghong Wang, Yumei Xiong, Jonitha Gardner, Li Yang, Jamila Gupte, Yan Gong, Zheng Pan, Gene Cutler, Paul D. Kassner, Hua Tu, Bei Shan, Xinle Wu, Yang Li	2014	2
2	Discovery and optimization of 5-(2-((1-(phenylsulfonyl)-1,2,3,4-tetrahydroquinolin-7-yl)oxy)pyridin-4-yl)-1,2,4-oxadiazoles as novel gpr119 agonists Bioorganic & Medicinal Chemistry Letters ·Yingcai Wang, Ming Yu, Jiang Zhu, Nadine Terry-Lawrence, Frank Kayser, Julio C. Medina, Jian-Hua Liu, Marion Conn, Bei Shan, Mark P. Grillo, Jiwen Jim Liu, Peter Coward	2014	9
3	Discovery and optimization of N-(3-(1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]pyridin-4-yloxy)phenyl)benzenesulfonamides as novel GPR119 agonists Bioorganic & Medicinal Chemistry Letters ·Ming Yu, Jian Zhang, Yingcai Wang, Jiang Zhu, Frank Kayser, Julio C. Medina, Jian-Hua Liu, Marion Conn, Bei Shan, Mark P. Grillo, Peter Coward, Jiwen Liu	2013	13
4	A Potent Class of GPR40 Full Agonists Engages the EnteroInsular Axis to Promote Glucose Control in Rodents PLoS ONE ·Jian Luo, Gayathri Swaminath, Sean P. Brown, Jane Zhang, Qi Guo, Michael Chen, Kathy Nguyen, Thanhvien Tran, Max Pogoriutschnig, Paul J. Dransfield, Marc Vimolratana, Jonathan B. Houze, Alain Audry, Maria M. Toteva, Bei Shan, Balladares Saltos, Run Zhuang, Daniel C.-H. Lin	2012	114
5	Optimization of triazoles as novel and potent nonphlorizin SGLT2 inhibitors Bioorganic & Medicinal Chemistry Letters ·Xiaohui Du, Mike E. Lizarzaburu, Simon Turcotte, TaeWeon Lee, Clémence Schmitt, Bei Shan, Peter W. Fan, Yun Ling, Julio C. Medina, Jonathan B. Houze	2011	13
6	Discovery of pyrrolopyridazines as novel DGAT1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Brian M. Fox, Kiyosei Iio, Kexue Li, Erhabor Aimien Gloria, Takashi Inaba, Simon Jackson, Shoichi Sagawa, Bei Shan, Masahiro Tanaka, Atsuhito Yoshida, Frank Kayser	2010	23
7	Identification and Characterization of a Non-retinoid Ligand for Retinol-binding Protein 4 Which Lowers Serum Retinol-binding Protein 4 Levels in Vivo Journal of Biological Chemistry ·Alykhan Motani, Zhulun Wang, Marion Conn, Jian-Hua Liu, Ying Zhang, Qingxiang Liu, Sheree Johnstone, Haoda Xu, E Wiesendanger, Yingcai Wang, Pingchen Fan, Richard Connors, Tal Brooke, Guifen Xu, Nigel P.C. Walker, Bei Shan, Peter Coward	2009	68
8	Distinctive molecular inhibition mechanisms for selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1 Bioorganic & Medicinal Chemistry ·Hua Tu, Jay P. Powers, Jinsong Liu, I. Golutvin, Athena Sudom, Xuelei Yan, Haoda Xu, David Meininger, Caroline Kovarski, Xiaodong He, Juan C. Jaén, Daqing Sun, Marc Labelle, Hiroshi Yamamoto, Bei Shan, Nigel P.C. Walker, Zhulun Wang	2008	30
9	The Crystal Structure of PCSK9: A Regulator of Plasma LDL-Cholesterol Structure ·Derek E. Piper, Simon Jackson, Qiang Liu, William G. Romanow, Susan Shetterly, Stephen T. Thibault, Bei Shan, Nigel P.C. Walker	2007	204
10	Sitosterolemia in ABC-Transporter G5-deficient mice is aggravated on activation of the liver-X receptor Gastroenterology ·Torsten Plösch, Vincent W. Bloks, Yuko Terasawa, G. Magnani, Jian-Hua Liu, K. Boecke, Ido P. Kema, Albert K. Groen, Bei Shan, Folkert Kuipers, Murodbek Ma’murjonovich Yangiboyev	2003	112
11	Enterohepatic Circulation of Bile Salts in Farnesoid X Receptor-deficient Mice Journal of Biological Chemistry ·Tineke Kok, Christian V. Hulzebos, Henk Wolters, Rick Havinga, Luis B. Agellon, Frans Stellaard, Bei Shan, Margrit Schwarz, Folkert Kuipers	2003	169
12	Loss of Nuclear Receptor SHP Impairs but Does Not Eliminate Negative Feedback Regulation of Bile Acid Synthesis Developmental Cell ·Thomas A. Kerr, Shigeru Saeki, Manfred Schneider, Karen E. Schaefer, G. Magnani, Arunima Karkun, Bei Shan, David W. Russell, Margrit Schwarz	2002	288
13	Transcription Factor MIZ-1 Is Regulated via Microtubule Association Molecular Cell ·Joseph M. Ziegelbauer, Bei Shan, Deborah Yager, Carolyn A. Larabell, B. Hoffmann, Robert Tjian	2001	78
14	The Hypocholesterolemic Agent LY295427 Reverses Suppression of Sterol Regulatory Element-binding Protein Processing Mediated by Oxysterols Journal of Biological Chemistry ·Bethany A. Janowski, Bei Shan, David W. Russell	2001	50
15	Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRα and LXRβ Genes & Development ·Joyce J. Repa, Guosheng Liang, Jiafu Ou, Yuriy K. Bashmakov, Huang QiLe, Iichiro Shimomura, Bei Shan, Maram Tammam, J GOLDSTEIN, David J. Mangelsdorf Hit paper breakdown →	2000	1431
16	Role of LXRs in control of lipogenesis Genes & Development ·Joshua R. Schultz, Hua Tu, Sandra VALABREGUE-PERRY, Joyce J. Repa, Julio C. Medina, Leping Li, Susan W. Schwendner, Shelley Wang, Martin Thoolen, David J. Mangelsdorf, Kevin D. Lustig, Bei Shan Hit paper breakdown →	2000	1394
17	Novel halogenated sulfonamides inhibit the growth of multidrug resistant MCF-7/ADR cancer cells Bioorganic & Medicinal Chemistry Letters ·Julio C. Medina, Daniel Roche, Bei Shan, R. Marc Learned, Walter Frankmoelle, David L. Clark, Terry Rosen, Juan C. Jaén	1999	72
18	CPF: An orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7α-hydroxylase gene Proceedings of the National Academy of Sciences ·Masahiro Nitta, Andreas Kiste, Chaline Brown, Herlina Dimiati, Bei Shan	1999	243
19	Characterization of a Novel 350-Kilodalton Nuclear Phosphoprotein That Is Specifically Involved in Mitotic-Phase Progression Molecular and Cellular Biology ·Xueliang Zhu, Michael A. Mancini, Kai‐Hsuan Chang, Chia‐Yang Liu, Chi‐Fen Chen, Bei Shan, D.R. Jones, Teresa L. Yang‐Feng, Wen‐Hwa Lee	1995	124
20	The Retinoblastoma Protein Region Required for Interaction with the E2F Transcription Factor Includes the T/E1A Binding and Carboxy-Terminal Sequences DNA and Cell Biology ·Shi Huang, 赵善成, Kelly-Ann Sheppard, Dung Van Chu, Bei Shan, Prince.Pinegah.K, Eva Y.-H.P. Lee, Amy S. Yee	1992	34

About Bei Shan

Bei Shan is a scholar working on Oncology, Ophthalmology, Biochemistry, Surgery and Endocrinology, Diabetes and Metabolism, having authored 31 papers that have together received 9.0k indexed citations. Recurring topics across this work include Drug Transport and Resistance Mechanisms (12 papers), Cholesterol and Lipid Metabolism (9 papers), Cancer-related Molecular Pathways (7 papers), Peroxisome Proliferator-Activated Receptors (6 papers), Diabetes Treatment and Management (4 papers), Receptor Mechanisms and Signaling (4 papers), Ocular Oncology and Treatments (4 papers) and Virus-based gene therapy research (3 papers). The work is most often cited by research in Oncology (4.3k citations), Biochemistry (951 citations), Surgery (5.4k citations), Molecular Biology (4.3k citations) and Cancer Research (915 citations). Bei Shan has collaborated with scholars based in United States, Japan and Netherlands. Frequent co-authors include David J. Mangelsdorf, Joyce J. Repa, Hua Tu, Kevin D. Lustig, R. Marc Learned, Joshua R. Schultz, Makoto Makishima, Mitchell Hull, Yuriy K. Bashmakov and Jiafu Ou. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Molecular and Cellular Biology, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences and Genes & Development.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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