Margarida Ruas

4.7k total citations · 2 hit papers
34 papers, 3.5k citations indexed

About

Margarida Ruas is a scholar working on Physiology, Molecular Biology and Sensory Systems. According to data from OpenAlex, Margarida Ruas has authored 34 papers receiving a total of 3.5k indexed citations (citations by other indexed papers that have themselves been cited), including 21 papers in Physiology, 11 papers in Molecular Biology and 10 papers in Sensory Systems. Recurrent topics in Margarida Ruas's work include Calcium signaling and nucleotide metabolism (21 papers), Ion Channels and Receptors (10 papers) and Adenosine and Purinergic Signaling (5 papers). Margarida Ruas is often cited by papers focused on Calcium signaling and nucleotide metabolism (21 papers), Ion Channels and Receptors (10 papers) and Adenosine and Purinergic Signaling (5 papers). Margarida Ruas collaborates with scholars based in United Kingdom, United States and Belgium. Margarida Ruas's co-authors include Gordon Peters, John Parrington, Katja Rietdorf, Michael X. Zhu, Lianne C. Davis, Abdelilah Arredouani, Anthony J. Morgan, Xiaotong Cheng, Lydia Teboul and Grant C. Churchill and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Margarida Ruas

34 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The p16INK4a/CDKN2A tumor suppressor and its relatives

1998 733 citations Margarida Ruas, Gordon Peters Biochimica et Biophysica Acta (BBA) - Reviews on Cancer profile →
NAADP mobilizes calcium from acidic organelles through two-pore channels

2009 621 citations Peter Calcraft, Margarida Ruas et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Margarida Ruas United Kingdom	26	1.7k	1.3k	854	612	518	34	3.5k
Sandy M. Price United States	22	318 0.2×	2.4k 1.9×	77 0.1×	538 0.9×	578 1.1×	28	3.8k
Frank T. Cooke United Kingdom	23	404 0.2×	3.1k 2.4×	29 0.0×	304 0.5×	2.1k 4.0×	34	4.3k
Hideki Shibata Japan	33	140 0.1×	2.1k 1.7×	36 0.0×	208 0.3×	1.5k 2.9×	83	2.9k
Seiji Torii Japan	28	295 0.2×	2.1k 1.7×	13 0.0×	321 0.5×	1.2k 2.4×	56	3.4k
Benny Motro Israel	23	46 0.0×	2.1k 1.6×	35 0.0×	263 0.4×	643 1.2×	34	2.9k
Yoshiteru Sasaki Japan	31	93 0.1×	1.9k 1.5×	302 0.4×	827 1.4×	312 0.6×	49	4.2k
D F Steiner United States	30	108 0.1×	1.6k 1.2×	26 0.0×	217 0.4×	480 0.9×	41	3.0k
Nancy Dahms United States	33	483 0.3×	2.5k 2.0×	10 0.0×	168 0.3×	1.4k 2.8×	82	4.0k
Annette Hille Germany	23	181 0.1×	1.1k 0.9×	16 0.0×	172 0.3×	829 1.6×	39	1.9k
Mingye Feng United States	20	73 0.0×	797 0.6×	178 0.2×	601 1.0×	130 0.3×	36	2.3k

Countries citing papers authored by Margarida Ruas

Since Specialization

Citations

This map shows the geographic impact of Margarida Ruas's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Margarida Ruas with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Margarida Ruas more than expected).

Fields of papers citing papers by Margarida Ruas

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Margarida Ruas. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Margarida Ruas. The network helps show where Margarida Ruas may publish in the future.

Co-authorship network of co-authors of Margarida Ruas

This figure shows the co-authorship network connecting the top 25 collaborators of Margarida Ruas. A scholar is included among the top collaborators of Margarida Ruas based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Margarida Ruas. Margarida Ruas is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Godwin, Jonathan, Margarida Ruas, Goli Ardestani, et al.. (2018). PLC zeta is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence. Genetics Research. 100. 3 indexed citations

Godwin, Jonathan, Margarida Ruas, Hoi Chang Lee, et al.. (2017). PLCζ is the physiological trigger of the Ca2+ oscillations that induce embryogenesis in mammals but conception can occur in its absence. Development. 144(16). 2914–2924. 122 indexed citations

Webb, Sarah, et al.. (2015). Two-Pore Channel 2 activity is required for slow muscle cell-generated Ca2+ signaling during myogenesis in intact zebrafish. The International Journal of Developmental Biology. 59(7-8-9). 313–325. 26 indexed citations

Capel, Rebecca A., Yanwen Wang, Wei Liu, et al.. (2015). Two-pore Channels (TPC2s) and Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) at Lysosomal-Sarcoplasmic Reticular Junctions Contribute to Acute and Chronic β-Adrenoceptor Signaling in the Heart. Journal of Biological Chemistry. 290(50). 30087–30098. 65 indexed citations

Davis, Lianne C., et al.. (2014). Measurement of Luminal pH of Acidic Stores as a Readout for NAADP Action. Cold Spring Harbor Protocols. 2014(10). pdb.prot076935–pdb.prot076935. 1 indexed citations

Davis, Lianne C., et al.. (2014). Preparation and Use of Sea Urchin Egg Homogenates for Studying NAADP-Mediated Ca²⁺ Release. Cold Spring Harbor Protocols. 2014(9). pdb.prot076901–pdb.prot076901. 5 indexed citations

Davis, Lianne C., et al.. (2014). Synthesis of NAADP-AM as a Membrane-Permeant NAADP Analog. Cold Spring Harbor Protocols. 2014(10). pdb.prot076927–pdb.prot076927. 3 indexed citations

Tsaih, Shirng‐Wern, Katie Holl, Shuang Jia, et al.. (2014). Identification of a Novel Gene for Diabetic Traits in Rats, Mice, and Humans. Genetics. 198(1). 17–29. 38 indexed citations

Kalungia, Aubrey Chichonyi, Duncan Bloor-Young, Margarida Ruas, et al.. (2013). The Involvement of NAADP and Two-Pore Ca2+ Channels in the Cardiac Beta-Adrenergic Response. Biophysical Journal. 104(2). 614a–614a. 1 indexed citations

10.

Kashir, Junaid, Céline Jones, Katja Rietdorf, et al.. (2011). Loss of activity mutations in phospholipase C zeta (PLC ) abolishes calcium oscillatory ability of human recombinant protein in mouse oocytes. Human Reproduction. 26(12). 3372–3387. 74 indexed citations

11.

Rietdorf, Katja, et al.. (2011). Two-pore Channels Form Homo- and Heterodimers. Journal of Biological Chemistry. 286(43). 37058–37062. 45 indexed citations

12.

Pitt, Samantha J., Elisa Venturi, Katja Rietdorf, et al.. (2010). TPC2 Is a Novel NAADP-sensitive Ca2+ Release Channel, Operating as a Dual Sensor of Luminal pH and Ca2+. Journal of Biological Chemistry. 285(45). 35039–35046. 189 indexed citations

13.

Heytens, Elke, John Parrington, Kevin Coward, et al.. (2009). Reduced amounts and abnormal forms of phospholipase C zeta (PLC ) in spermatozoa from infertile men. Human Reproduction. 24(10). 2417–2428. 234 indexed citations

14.

Calcraft, Peter, Margarida Ruas, Zui Pan, et al.. (2009). NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature. 459(7246). 596–600. 621 indexed citations breakdown →

15.

Davis, Lianne C., Anthony J. Morgan, Margarida Ruas, et al.. (2008). Ca2+ Signaling Occurs via Second Messenger Release from Intraorganelle Synthesis Sites. Current Biology. 18(20). 1612–1618. 55 indexed citations

16.

Ruas, Margarida, et al.. (2005). NAADP receptors. Cell Calcium. 38(3-4). 273–280. 48 indexed citations

17.

Ruas, Margarida, Sharon Brookes, Neil Q. McDonald, & Gordon Peters. (1999). Functional evaluation of tumour-specific variants of p16INK4a/CDKN2A: correlation with protein structure information. Oncogene. 18(39). 5423–5434. 58 indexed citations

18.

Ruas, Margarida & Gordon Peters. (1998). The p16INK4a/CDKN2A tumor suppressor and its relatives. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1378(2). F115–F177. 733 indexed citations breakdown →

19.

Kato, Daishiro, Margarida Ruas, Maria Starborg, et al.. (1998). Features of replicative senescence induced by direct addition of antennapedia‐p16^INK4A fusion protein to human diploid fibroblasts. FEBS Letters. 427(2). 203–208. 74 indexed citations

20.

Kranendonk, Michel, Margarida Ruas, A. Laires, & José Rueff. (1994). Isolation and prevalidation of an Escherichia coli tester strain for the use in mechanistic and metabolic studies of genotoxins. Mutation Research/Environmental Mutagenesis and Related Subjects. 312(2). 99–109. 10 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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