Manuela Santarosa

7.9k total citations · 1 hit paper
32 papers, 5.7k citations indexed

About

Manuela Santarosa is a scholar working on Molecular Biology, Oncology and Pathology and Forensic Medicine. According to data from OpenAlex, Manuela Santarosa has authored 32 papers receiving a total of 5.7k indexed citations (citations by other indexed papers that have themselves been cited), including 20 papers in Molecular Biology, 13 papers in Oncology and 7 papers in Pathology and Forensic Medicine. Recurrent topics in Manuela Santarosa's work include DNA Repair Mechanisms (7 papers), BRCA gene mutations in cancer (6 papers) and Genetic factors in colorectal cancer (5 papers). Manuela Santarosa is often cited by papers focused on DNA Repair Mechanisms (7 papers), BRCA gene mutations in cancer (6 papers) and Genetic factors in colorectal cancer (5 papers). Manuela Santarosa collaborates with scholars based in Italy, Ukraine and United Kingdom. Manuela Santarosa's co-authors include Alan Ashworth, Graeme C.M. Smith, Ian Hickson, Charlotte Knights, Andrew Tutt, Damian A. Johnson, Nuala McCabe, Christopher J. Lord, Stephen P. Jackson and Hannah Farmer and has published in prestigious journals such as Nature, Cancer and International Journal of Molecular Sciences.

In The Last Decade

Manuela Santarosa

31 papers receiving 5.6k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

2005 4.8k citations Hannah Farmer, Nuala McCabe et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Manuela Santarosa Italy	18	4.0k	3.8k	1.1k	1.0k	627	32	5.7k
Ian Hickson United Kingdom	16	4.8k 1.2×	4.2k 1.1×	996 0.9×	1.0k 1.0×	571 0.9×	28	6.4k
Hannah Farmer United Kingdom	7	4.2k 1.1×	3.8k 1.0×	980 0.9×	1.2k 1.2×	524 0.8×	7	6.0k
Damian A. Johnson United Kingdom	4	3.5k 0.9×	3.6k 0.9×	874 0.8×	802 0.8×	493 0.8×	4	4.9k
Charlotte Knights United Kingdom	6	3.8k 1.0×	3.9k 1.0×	914 0.9×	770 0.7×	515 0.8×	13	5.4k
Nuala McCabe United Kingdom	19	5.1k 1.3×	5.0k 1.3×	1.3k 1.2×	1.2k 1.1×	741 1.2×	43	7.2k
Alan Lau United Kingdom	31	5.1k 1.3×	5.1k 1.4×	1.2k 1.2×	1.0k 1.0×	691 1.1×	61	7.3k
Suzanne Kyle United Kingdom	20	4.2k 1.1×	4.2k 1.1×	804 0.8×	622 0.6×	433 0.7×	23	5.6k
Niklas Schultz Sweden	22	5.5k 1.4×	4.3k 1.1×	847 0.8×	1.0k 1.0×	562 0.9×	32	6.9k
David S. Boss Netherlands	14	2.5k 0.6×	3.1k 0.8×	939 0.9×	778 0.7×	769 1.2×	24	4.4k
Elena López‐Knowles United Kingdom	24	4.6k 1.1×	4.3k 1.1×	1.3k 1.3×	2.1k 2.0×	1.2k 1.9×	46	7.3k

Countries citing papers authored by Manuela Santarosa

Since Specialization

Citations

This map shows the geographic impact of Manuela Santarosa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manuela Santarosa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manuela Santarosa more than expected).

Fields of papers citing papers by Manuela Santarosa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manuela Santarosa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manuela Santarosa. The network helps show where Manuela Santarosa may publish in the future.

Co-authorship network of co-authors of Manuela Santarosa

This figure shows the co-authorship network connecting the top 25 collaborators of Manuela Santarosa. A scholar is included among the top collaborators of Manuela Santarosa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Manuela Santarosa. Manuela Santarosa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Santarosa, Manuela, et al.. (2025). Beyond repair: Expanding roles of BRCA1 in RNA processing and cancer. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1880(6). 189499–189499.

Santarosa, Manuela, et al.. (2024). Beyond self‑eating: Emerging autophagy‑independent functions for the autophagy molecules in cancer (Review). International Journal of Oncology. 64(6). 4 indexed citations

Santarosa, Manuela, et al.. (2023). In Silico Identification of a BRCA1:miR-29:DNMT3 Axis Involved in the Control of Hormone Receptors in BRCA1-Associated Breast Cancers. International Journal of Molecular Sciences. 24(12). 9916–9916. 2 indexed citations

Spessotto, Paola, et al.. (2020). The Autophagy Machinery Contributes to E-cadherin Turnover in Breast Cancer. Frontiers in Cell and Developmental Biology. 8. 545–545. 20 indexed citations

Brisotto, Giulia, Tiziana Perin, Antonella Zucchetto, et al.. (2018). A p53/miR-30a/ZEB2 axis controls triple negative breast cancer aggressiveness. Cell Death and Differentiation. 25(12). 2165–2180. 82 indexed citations

Brisotto, Giulia, et al.. (2016). Epigenetic silencing of miR‐200c in breast cancer is associated with aggressiveness and is modulated by ZEB1. Genes Chromosomes and Cancer. 56(2). 147–158. 49 indexed citations

Brisotto, Giulia, et al.. (2015). An improved sequencing-based strategy to estimate locus-specific DNA methylation. BMC Cancer. 15(1). 639–639. 8 indexed citations

Santarosa, Manuela & Roberta Maestro. (2011). BRACking news on triple-negative/basal-like breast cancers: how BRCA1 deficiency may result in the development of a selective tumor subtype. Cancer and Metastasis Reviews. 31(1-2). 131–142. 10 indexed citations

Santarosa, Manuela, Alessandra Viel, Nicoletta Bivi, et al.. (2010). BRCA1 modulates the expression of hnRNPA2B1 and KHSRP. Cell Cycle. 9(23). 4666–4673. 23 indexed citations

10.

Santarosa, Manuela, et al.. (2009). Premature senescence is a major response to DNA cross-linking agents in BRCA1-defective cells: implication for tailored treatments of BRCA1 mutation carriers. Molecular Cancer Therapeutics. 8(4). 844–854. 28 indexed citations

11.

Pastrello, Chiara, Manuela Santarosa, Mara Fornasarig, et al.. (2005). MUC Gene Abnormalities in Sporadic and Hereditary Mucinous Colon Cancers with Microsatellite Instability. Disease Markers. 21(3). 121–126. 12 indexed citations

12.

Farmer, Hannah, Nuala McCabe, Christopher J. Lord, et al.. (2005). Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy. Nature. 434(7035). 917–921. 4751 indexed citations breakdown →

13.

Marroni, Fabio, Paolo Aretini, Emma D’Andrea, et al.. (2004). Penetrances of breast and ovarian cancer in a large series of families tested for BRCA1/2 mutations. European Journal of Human Genetics. 12(11). 899–906. 41 indexed citations

14.

Viel, Alessandra, Elisabetta Novella, Maurizio Genuardi, et al.. (1998). Lack of PMS2 gene-truncating mutations in patients with hereditary colorectal cancer.. International Journal of Oncology. 13(3). 565–9. 25 indexed citations

15.

Santarosa, Manuela, Alessandra Viel, Riccardo Dolcetti, et al.. (1998). Low incidence of BRCA1 mutations among Italian families with breast and ovarian cancer. International Journal of Cancer. 78(5). 581–586. 2 indexed citations

16.

Santarosa, Manuela, D. Favaro, Michele Quaia, & Enzo Galligioni. (1997). Expression of heat shock protein 72 in renal cell carcinoma: Possible role and prognostic implications in cancer patients. European Journal of Cancer. 33(6). 873–877. 90 indexed citations

17.

Galligioni, Enzo, Michele Quaia, Antonino Carbone, et al.. (1996). Adjuvant immunotherapy treatment of renal carcinoma patients with autologous tumor cells and Bacillus Calmette-Guèrin: Five-year results of a prospective randomized study. Cancer. 77(12). 2560–2566. 117 indexed citations

18.

Santarosa, Manuela, D. Favaro, Michele Quaia, et al.. (1995). Expression and release of intercellular adhesion molecule‐1 in renal‐cancer patients. International Journal of Cancer. 62(3). 271–275. 31 indexed citations

19.

Favaro, D., Manuela Santarosa, Michele Quaia, et al.. (1995). Soluble Intercellular Adhesion Molecule-1 and Serum Cytokines in Melanoma Patients Treated with Liposomes Containing Muramyl Tripeptide. Tumori Journal. 81(3). 185–190. 2 indexed citations

20.

Galligioni, Enzo, Michele Quaia, Antonino Carbone, et al.. (1993). Randomized Study of Adjuvant Immunotherapy with Autologous Tumor Cells and BCG in Renal Cancer. Annals of the New York Academy of Sciences. 690(1). 367–369. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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