Manuel Yepes

7.2k citations

95 papers · 5.9k indexed · 1 hit paper · h-index 41

Impact in

Neurology top 0.5%
- Neuroinflammation and Neurodegeneration Mechanisms
- Barrier Structure and Function Studies
Cancer Research top 0.5%
- Protease and Inhibitor Mechanisms

Papers in

Cancer Research 55
- Protease and Inhibitor Mechanisms 45
- NF-κB Signaling Pathways 9
Neurology 19
- Neuroinflammation and Neurodegeneration Mechanisms 12

Co-authors: Daniel A. Lawrence Dudley K. Strickland Maria Sandkvist Elizabeth Moore Thomas H. Bugge Rohini Polavarapu Jie An Timothy A. Coleman
Journals: Journal of Cerebral Blood Flow & Metabolism (10 papers)Journal of Biological Chemistry (7 papers)Journal of Clinical Investigation (6 papers)Journal of Neuroscience (6 papers)Neuroscience (5 papers)
Partner nations: United States China France

In The Last Decade

Manuel Yepes

94 papers receiving 5.9k citations

Hit Papers

align trajectories log scale

A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone 2010 · 550 citations

Peers

Countries citing papers authored by Manuel Yepes

Since Specialization

Citations

This map shows the geographic impact of Manuel Yepes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Manuel Yepes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Manuel Yepes more than expected).

Fields of papers citing papers by Manuel Yepes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Manuel Yepes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Manuel Yepes. The network helps show where Manuel Yepes may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Manuel Yepes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Manuel Yepes Line = papers co-authored together Manuel Yepes links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Pan-caspase inhibitor protects against noise-induced hearing loss in a rodent model Frontiers in Neuroscience ·Manuel Yepes, Forgógépek Hajtott, D.W. Branch, Mario O. Salazar, Suhrud M. Rajguru	2025	1
2	Reprint of: Fibrinolytic and Non-fibrinolytic Roles of Tissue-type Plasminogen Activator in the Ischemic Brain Neuroscience ·Manuel Yepes	2024	1
3	Plasminogen activator inhibitor-1 mediates cerebral ischemia-induced astrocytic reactivity Journal of Cerebral Blood Flow & Metabolism ·سهلة نوريزاد, Cynthia Martín-Jiménez, Stanley Pignal, Ch. Lykomitrou, Deigo Adit Dwi Prasetyo, I.G. Bogacheva, Todd M. Preuss, Xiaodong Zhang, Manuel Yepes	2024	2
4	Simulation-based education in neurology: lessons from the COVID-19 pandemic BMC Research Notes ·Суханов Е.С., Anna Oliveira, 赵凌燕, Joe Gelt, JANEIDE LIMA JANUÁRIO DE OLIVEIRA DAMASCENO, Давыдова Ирина Исаговна, حسين عباس مراد, Manuel Yepes	2023	1
5	Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain Journal of Cerebral Blood Flow & Metabolism ·Ariel Díaz, Paola Merino, Othón Torres Figueroa, Manuel Yepes, 知文小田, Enrique Torre, Liliana de Oliveira Rocha, Xiaodong Zhang, Chadwick M. Hales, Frank Tong	2021	5
6	Urokinase-type plasminogen activator is a modulator of synaptic plasticity in the central nervous system: implications for neurorepair in the ischemic brain Neural Regeneration Research ·Manuel Yepes	2019	19
7	Urokinase-type Plasminogen Activator Promotes Synaptic Recovery In The Ischemic Brain PubMed ·Manuel Yepes	2018	1
8	Tissue-type plasminogen activator is a modulator of the synaptic vesicle cycle Neural Regeneration Research ·Manuel Yepes	2016	2
9	Urokinase-Type Plasminogen Activator Promotes Dendritic Spine Recovery and Improves Neurological Outcome Following Ischemic Stroke Journal of Neuroscience ·Fang Wu, 川畑雅樹, Ramiro Echeverry, Enrique Torre, Woldeab B. Haile, Jie An, Chang‐Hua Chen, Lihong Cheng, Hai Toan Le, Frank Tong, Jae-Keun Park, Manuel Yepes	2014	46
10	ASPECTS decay during inter-facility transfer predicts patient outcomes in endovascular reperfusion for ischemic stroke: a unique assessment of dynamic physiologic change over time Journal of NeuroInterventional Surgery ·Chung‐Huan Sun, Francisco Javier Montes Aguilar, Raul G. Nogueira, Brenda A Glenn, Ch. Derouesné, L. O. Boiechko, Deborah Camp, Leanne K. Secker, 平博敏, Ana Catarina Ayres Chometon Oliveira, Michael Frankel, Samir Belagaje, Aaron Anderson, Fadi Nahab, Manuel Yepes, Rishi Gupta	2014	38
11	Tissue-type plasminogen activator mediates neuroglial coupling in the central nervous system Neuroscience ·Jie An, Woldeab B. Haile, Fe‐Lin Lin Wu, Enrique Torre, Manuel Yepes	2013	40
12	The cytokine tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 have a neuroprotective effect in the central nervous system Journal of Neuroinflammation ·Ramiro Echeverry, Fang Wu, Woldeab B. Haile, Jialing Wu, Manuel Yepes	2012	22
13	Identification of a Novel Small Molecule HIF-1α Translation Inhibitor Clinical Cancer Research ·Takuhito Narita, Shaoman Yin, Christine F. Gelin, Carlos S. Moreno, Manuel Yepes, K. C. Nicolaou, Erwin G. Van Meir	2009	99
14	Synthesis, structural activity-relationships, and biological evaluation of novel amide-based allosteric binding site antagonists in NR1A/NR2B N-methyl-d-aspartate receptors Bioorganic & Medicinal Chemistry ·I. Roles, Scott J. Myers, Stefan Zielicz, فايزة زيد متعب السيبية, Yesim A. Tahirovic, Natalie L. Kurtkaya, Praseeda Mullasseril, Hongjie Yuan, Polina Lyuboslavsky, Phuong Le, Lawrence J. Wilson, Manuel Yepes, Raymond Dingledine, Stephen F. Traynelis, Dennis C. Liotta	2009	27
15	The Low-Density Lipoprotein Receptor-Related Protein 1 Mediates Tissue-Type Plasminogen Activator-Induced Microglial Activation in the Ischemic Brain American Journal Of Pathology ·Chen Zhang, Jie An, Dudley K. Strickland, Manuel Yepes	2009	68
16	Tissue-type plasminogen activator in the ischemic brain: more than a thrombolytic Trends in Neurosciences ·Manuel Yepes, Benoit D. Roussel, Carine Ali, Denis Vivien	2008	233
17	Plasmin Potentiates Synaptic N-Methyl-D-aspartate Receptor Function in Hippocampal Neurons through Activation of Protease-activated Receptor-1 Journal of Biological Chemistry ·Guido Mannaioni, Anna G. Orr, Cecily E. Hamill, Hongjie Yuan, Sajjad M. Yousafzai, Kelly L. McCoy, Rolando Berlinguer‐Palmini, Candice Junge, C. Justin Lee, Manuel Yepes, John R. Hepler, Stephen F. Traynelis	2008	59
18	Regulated Intramembrane Proteolysis of the Low-Density Lipoprotein Receptor-Related Protein Mediates Ischemic Cell Death American Journal Of Pathology ·Rohini Polavarapu, Jie An, Chen Zhang, Manuel Yepes	2008	44
19	Mutants of Plasminogen Activator Inhibitor-1 Designed to Inhibit Neutrophil Elastase and Cathepsin G Are More Effective in Vivo than Their Endogenous Inhibitors Journal of Biological Chemistry ·Steingrimur Stefansson, Manuel Yepes, Natalia Gorlatova, Duane E. Day, Vina Astika, Tadayuki MINOURA, Grainne A. McMahon, Daniel A. Lawrence	2004	22
20	Regulation of seizure spreading by neuroserpin and tissue-type plasminogen activator is plasminogen-independent Journal of Clinical Investigation ·Manuel Yepes, Maria Sandkvist, Timothy A. Coleman, Elizabeth Moore, Emily Finley, David Mitola, Thomas Bugge, Daniel A. Lawrence	2002	111

About Manuel Yepes

Manuel Yepes is a scholar working on Cancer Research, Neurology, Hematology, Cell Biology and Epidemiology, having authored 95 papers that have together received 5.9k indexed citations. Recurring topics across this work include Protease and Inhibitor Mechanisms (45 papers), Acute Ischemic Stroke Management (26 papers), Calpain Protease Function and Regulation (19 papers), Blood Coagulation and Thrombosis Mechanisms (19 papers), S100 Proteins and Annexins (19 papers), Neuroinflammation and Neurodegeneration Mechanisms (12 papers), Alzheimer's disease research and treatments (10 papers) and NF-κB Signaling Pathways (9 papers). The work is most often cited by research in Neurology (1.2k citations), Cancer Research (1.9k citations), Hematology (895 citations), Developmental Neuroscience (323 citations) and Cellular and Molecular Neuroscience (853 citations). Manuel Yepes has collaborated with scholars based in United States, China and France. Frequent co-authors include Daniel A. Lawrence, Dudley K. Strickland, Maria Sandkvist, Elizabeth Moore, Thomas H. Bugge, Rohini Polavarapu, Jie An, Timothy A. Coleman, Denis Vivien and Ramiro Echeverry. Their work appears in journals such as Journal of Cerebral Blood Flow & Metabolism, Journal of Biological Chemistry, Journal of Clinical Investigation, Journal of Neuroscience and Neuroscience.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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