M. L. HOEFLE

772 citations

18 papers · 613 indexed · h-index 11

Impact in

Organic Chemistry top 10%
- Asymmetric Synthesis and Catalysis
- Synthesis and biological activity
- Catalytic C–H Functionalization Methods
Biotechnology

Papers in

Organic Chemistry 11
- Synthesis and Characterization of Heterocyclic Compounds 3
- Synthesis and Reactions of Organic Compounds 3
- Organic Chemistry Cycloaddition Reactions 2
Pharmacology 2

Co-authors: Bruce D. Roth Ann Holmes Roger S. Newton Drago R. Sliskovic C. John Blankley Robert Meyer Daniel F. Ortwine Arnold D. Essenburg
Journals: Journal of Medicinal Chemistry (14 papers)Journal of the American Chemical Society (1 paper)Bioorganic & Medicinal Chemistry Letters (1 paper)ChemInform (1 paper)
Partner nations: United States

In The Last Decade

M. L. HOEFLE

18 papers receiving 540 citations

Peers

Countries citing papers authored by M. L. HOEFLE

Since Specialization

Citations

This map shows the geographic impact of M. L. HOEFLE's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by M. L. HOEFLE with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites M. L. HOEFLE more than expected).

Fields of papers citing papers by M. L. HOEFLE

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by M. L. HOEFLE. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by M. L. HOEFLE. The network helps show where M. L. HOEFLE may publish in the future.

Co-authors

The 25 scholars most cited alongside M. L. HOEFLE, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with M. L. HOEFLE Line = papers co-authored together M. L. HOEFLE links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

18 of 18 papers shown

#	Work
1	The early history of Parke-Davis and Company M. L. HOEFLE	2000	7
2	Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents Journal of Medicinal Chemistry ·Bruce D. Roth, C. John Blankley, M. L. HOEFLE, Ann Holmes, W. Howard Roark, Bharat K. Trivedi, Arnold D. Essenburg, Karen A. Kieft, Brian R. Krause, Richard L. Stanfield	1992	57
3	Conversion of NSAIDS into balanced dual inhibitors of cyclooxygenase and 5-lipoxygenase Bioorganic & Medicinal Chemistry Letters ·Diane H. Boschelli, David T. Connor, M. L. HOEFLE, Dirk A. Bornemeier, Richard D. Dyer	1992	10
4	Synthesis and antiarrhythmic activity of cis-2,6-dimethyl-.alpha.,.alpha.-diaryl-1-piperidinebutanols Journal of Medicinal Chemistry ·M. L. HOEFLE, LEONARD T. BLOUIN, Robert W. Fleming, S. G. Hastings, J. M. HINKLEY, T E Mertz, Thomas J. Steffe, Cedric Stratton	1991	6
5	Inhibitors of cholesterol biosynthesis. 3. Tetrahydro-4-hydroxy-6-[2-(1H-pyrrol-1-yl)ethyl]-2H-pyran 2-one inhibitors of HMG-CoA reductase. 2. Effects of introducing substituents at positions three and four of the pyrrole nucleus Journal of Medicinal Chemistry ·Bruce D. Roth, C. John Blankley, Alexander Chucholowski, Erika Ferguson, M. L. HOEFLE, Daniel F. Ortwine, Roger S. Newton, Catherine Sekerke, Drago R. Sliskovic, Michael Wilson	1991	151
6	Synthesis and antiarrhythmic activity of .alpha.-[(diarylmethoxy)methyl]-1-piperidineethanols Journal of Medicinal Chemistry ·M. L. HOEFLE, LEONARD T. BLOUIN, Robert W. Fleming, S. G. Hastings, J. M. HINKLEY, T E Mertz, Thomas J. Steffe, Cedric Stratton, Leslie M. Werbel	1991	5
7	ChemInform Abstract: Inhibitors of Cholesterol Biosynthesis. Part 3. Tetrahydro‐4‐hydroxy‐6‐ (2‐(1H‐pyrrol‐1‐yl)ethyl)‐2H‐pyran‐2‐one Inhibitors of HMG‐CoA Reductase. Part 2. Effects of Introducing Substituents at Positions Three and Four of the Pyrrole Nucleus. ChemInform ·Bruce D. Roth, C. John Blankley, Alexander Chucholowski, Erika Ferguson, M. L. HOEFLE, Daniel F. Ortwine, Roger S. Newton, Catherine Sekerke, Drago R. Sliskovic, Charlotte D. Stratton, Marina Wilson	1991	1
8	Inhibitors of cholesterol biosynthesis. 2. 1,3,5-Trisubstituted [2-(tetrahydro-4-hydroxy-2-oxopyran-6-yl)ethyl]pyrazoles Journal of Medicinal Chemistry ·Drago R. Sliskovic, Bruce D. Roth, Marina Wilson, M. L. HOEFLE, Roger S. Newton	1990	48
9	Inhibitors of cholesterol biosynthesis. 1. trans-6-(2-Pyrrol-1-ylethyl)-4-hydroxypyran-2-ones, a novel series of HMG-CoA reductase inhibitors. 1. Effects of structural modifications at the 2- and 5-positions of the pyrrole nucleus Journal of Medicinal Chemistry ·Bruce D. Roth, Daniel F. Ortwine, M. L. HOEFLE, Charlotte D. Stratton, Drago R. Sliskovic, Marina Wilson, Roger S. Newton	1990	51
10	Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types Journal of Medicinal Chemistry ·S. KLUTCHKO, C. John Blankley, Robert W. Fleming, J. M. HINKLEY, Andreas Werner, Ingalill Nordin, Ann Holmes, M. L. HOEFLE, David Cohen	1986	60
11	Phenylenebis(oxy)bis[2,2-dimethylpentanoic acids]: agents that elevate high-density lipoproteins Journal of Medicinal Chemistry ·Ila Sircar, M. L. HOEFLE, Richard E. Maxwell	1983	14
12	Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at postions 2 and 5 of the hexanoic acid portion Journal of Medicinal Chemistry ·Ronald G. Almquist, Jac Crase, Clive Jennings-White, Robert Meyer, M. L. HOEFLE, Ronald D. Smith, Arnold D. Essenburg, Harvey Kaplan	1982	34
13	Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogs: potent angiotensin converting enzyme inhibitors Journal of Medicinal Chemistry ·Robert Meyer, Ernest D. Nicolaides, Francis G. Tinney, Elizabeth A. Lunney, Ann Holmes, M. L. HOEFLE, Ronald D. Smith, Arnold D. Essenburg, Harvey Kaplan, Ronald G. Almquist	1981	33
14	Synthesis and angiotensin-converting enzyme inhibitory activity of 3-(mercaptomethyl)-2-oxo-1-pyrrolidineacetic acids and 3-(mercaptomethyl)-2-oxo-1-piperidineacetic acids Journal of Medicinal Chemistry ·S. KLUTCHKO, M. L. HOEFLE, Ronald D. Smith, Arnold D. Essenburg, Robert B. Parker, Vicki L. Nemeth, Michael J. Ryan, Deborah H. Dugan, Harvey Kaplan	1981	31
15	Cardioselective .beta.-adrenergic blocking agents. 1. 1-[(3,4-Dimethoxyphenethyl)amino]-3-aryloxy-2-propanols Journal of Medicinal Chemistry ·M. L. HOEFLE, S. G. Hastings, Robert Meyer, Ruth M. Corey, Ann Holmes, Charlotte D. Stratton	1975	45
16	Diuretics. 4-Substituted 3-sulfamoylbenzoic acid hydrazides Journal of Medicinal Chemistry ·M. L. HOEFLE, LEONARD T. BLOUIN, H. A. DEWALD, Ann Holmes, Dorothy Williams	1968	5
17	Diuretics. 3-Amino- and 3-hydroxy-7-chloro-3,4-dihydro-4-oxo-6-quinazolinesulfonamides Journal of Medicinal Chemistry ·M. L. HOEFLE, Ann Holmes	1968	3
18	Pyrimido [4,5-d]pyrimidines. Part I Journal of the American Chemical Society ·Edward C. Taylor, Robert J. Knopf, Robert Meyer, Ann Holmes, M. L. HOEFLE	1960	52

About M. L. HOEFLE

M. L. HOEFLE is a scholar working on Organic Chemistry, Pharmacology, Molecular Biology, Pharmacology and Surgery, having authored 18 papers that have together received 613 indexed citations. Recurring topics across this work include Plant biochemistry and biosynthesis (4 papers), Steroid Chemistry and Biochemistry (3 papers), Cholesterol and Lipid Metabolism (3 papers), Phenothiazines and Benzothiazines Synthesis and Activities (3 papers), Lipoproteins and Cardiovascular Health (3 papers), Synthesis and Characterization of Heterocyclic Compounds (3 papers), Synthesis and Reactions of Organic Compounds (3 papers) and Organic Chemistry Cycloaddition Reactions (2 papers). The work is most often cited by research in Organic Chemistry (304 citations), Biotechnology (43 citations), Pharmaceutical Science (28 citations), Computational Theory and Mathematics (71 citations) and Pharmacology (73 citations). M. L. HOEFLE has collaborated with scholars based in United States. Frequent co-authors include Bruce D. Roth, Ann Holmes, Roger S. Newton, Drago R. Sliskovic, C. John Blankley, Robert Meyer, Daniel F. Ortwine, Arnold D. Essenburg, Catherine Sekerke and Alexander Chucholowski. Their work appears in journals such as Journal of Medicinal Chemistry, Journal of the American Chemical Society, Bioorganic & Medicinal Chemistry Letters and ChemInform.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact