Lyuben Tsvetkov

2.5k citations

19 papers · 1.8k indexed · 1 hit paper · h-index 14

Impact in

Oncology top 2%
- Cancer-related Molecular Pathways
- Cancer Immunotherapy and Biomarkers
- CAR-T cell therapy research
Cell Biology top 5%
- Microtubule and mitosis dynamics

Papers in

Cell Biology 7
- Microtubule and mitosis dynamics 7
Oncology 11
- Cancer-related Molecular Pathways 10

Co-authors: Hong SunHui ZhangKun‐Huei Yeh David F. Stern Xingzhi XuJia LiValia T. Mihaylova Nadia J. Gavrilova
Journals: Cell Cycle (3 papers)Current Biology (2 papers)Journal of Biological Chemistry (2 papers)Molecular Carcinogenesis (1 paper)Clinical Cancer Research (1 paper)
Partner nations: United States Bulgaria France

In The Last Decade

Lyuben Tsvetkov

19 papers receiving 1.8k citations

Hit Papers

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p27Kip1 ubiquitination and degradation is regulated by the SCFSkp2 complex through phosphorylated Thr187 in p27 1999 · 683 citations

Peers

Countries citing papers authored by Lyuben Tsvetkov

Since Specialization

Citations

This map shows the geographic impact of Lyuben Tsvetkov's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lyuben Tsvetkov with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lyuben Tsvetkov more than expected).

Fields of papers citing papers by Lyuben Tsvetkov

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lyuben Tsvetkov. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lyuben Tsvetkov. The network helps show where Lyuben Tsvetkov may publish in the future.

Co-authors

The 25 scholars most cited alongside Lyuben Tsvetkov, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lyuben Tsvetkov Line = papers co-authored together Lyuben Tsvetkov links everyone, so they are left out of the graph.

All Works

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19 of 19 papers shown

#	Work
1	PF558 THE ANTI-BCMA ANTIBODY-DRUG CONJUGATE GSK2857916 DRIVES IMMUNOGENIC CELL DEATH AND IMMUNE-MEDIATED ANTI-TUMOR RESPONSES, AND IN COMBINATION WITH AN OX40 AGONIST POTENTIATES IN VIVO ACTIVITY HemaSphere ·Rocío Montes de, Sabyasachi Bhattacharya, Nick Vitali, Keval Patel, Heather Kaczynski, Hong Shi, Christina Blackwell, Laura Seestaller‐Wehr, Dale A. Cooper, Hollie J. Jackson, Lyuben Tsvetkov, Oliver Kepp, Mark Creighton-Gutteridge, Christopher B. Hopson, Jeannie C. Yang, Guido Kroemer, Patrick A. Mayes, Christopher A. Shelton, A Alavi, Axel Hoos	2019	14
2	The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4 Clinical Cancer Research ·Li Liu, Patrick A. Mayes, Stephen D. Eastman, Hong Shi, Sapna Yadavilli, Tianqian Zhang, Jingsong Yang, Laura Seestaller‐Wehr, Shuyun Zhang, Chris Hopson, Lyuben Tsvetkov, Junping Jing, Shu Zhang, James Smothers, Axel Hoos	2015	352
3	Developing structure–activity relationships from an HTS hit for inhibition of the Cks1–Skp2 protein–protein interaction Bioorganic & Medicinal Chemistry Letters ·Rajinder Singh, Arvinder Sran, D. C. Carroll, Jianing Huang, Lyuben Tsvetkov, Xiulan Zhou, Julie Sheung, Esther M. John, Sarkiz D. Issakani, Donald G. Payan, Simon J. Shaw	2015	25
4	Centrosomal Chk2 in DNA damage responses and cell cycle progession Cell Cycle ·Amnon Golan, Elah Pick, Lyuben Tsvetkov, Yasmine Nadler, Harriet M. Kluger, David F. Stern	2010	21
5	The ubiquitin–proteasome system and assays to determine responses to inhibitors Expert Opinion on Drug Discovery ·Lyuben Tsvetkov, Meera Nanjundan, Maria Domino, Kenyon G. Daniel	2010	5
6	Approaches to Discovering Drugs that Regulate E3 Ubiquitin Ligases PubMed ·Ji Huang, Lyuben Tsvetkov, Kun Qu, Sarkiz Daniel-Issakani, Donald G. Payan	2008	2
7	Interaction of Chromatin-associated Plk1 and Mcm7 Journal of Biological Chemistry ·Lyuben Tsvetkov, David F. Stern	2005	44
8	The Plk1 Polo Box Domain Mediates a Cell Cycle and DNA Damage Regulated Interaction with Chk2 Cell Cycle ·Lyuben Tsvetkov, Rumiana T. Tsekova, Xingzhi Xu, David F. Stern	2005	18
9	Phosphorylation of Plk1 at S137 and T210 is Inhibited in Response to DNA Damage Cell Cycle ·Lyuben Tsvetkov, David F. Stern	2004	54
10	Polo‐like Kinases and Chk2 at the Interface of DNA Damage Checkpoint Pathways and Mitotic Regulation IUBMB Life ·Lyuben Tsvetkov	2004	6
11	Polo-like Kinase 1 and Chk2 Interact and Co-localize to Centrosomes and the Midbody Journal of Biological Chemistry ·Lyuben Tsvetkov, Xingzhi Xu, Jia Li, David F. Stern	2003	119
12	Chk2 Activation and Phosphorylation-Dependent Oligomerization Molecular and Cellular Biology ·Xingzhi Xu, Lyuben Tsvetkov, David F. Stern	2002	148
13	The F-Box Protein SKP2 Binds to the Phosphorylated Threonine 380 in Cyclin E and Regulates Ubiquitin-Dependent Degradation of Cyclin E Biochemical and Biophysical Research Communications ·Kun‐Huei Yeh, Takeshi Kondo, Jian‐Yu Zheng, Lyuben Tsvetkov, Jenny Blair, Hui Zhang	2001	48
14	PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27KIP1 through the ubiquitin E3 ligase SCFSKP2 Current Biology ·Ramanaiah Mamillapalli, Nadia J. Gavrilova, Valia T. Mihaylova, Lyuben Tsvetkov, Hong Wu, Hui Zhang, Hong Sun	2001	193
15	Promotion of S-phase entry and cell growth under serum starvation by SAG/ROC2/Rbx2/Hrt2, an E3 ubiquitin ligase component: Association with inhibition of p27 accumulation Molecular Carcinogenesis ·Hangjun Duan, Lyuben Tsvetkov, Yalun Liu, Ying Song, Manju Swaroop, Rong Wen, Hsiang‐Fu Kung, Hui Zhang, Yi Sun	2001	35
16	p27Kip1 ubiquitination and degradation is regulated by the SCFSkp2 complex through phosphorylated Thr187 in p27 Current Biology ·Lyuben Tsvetkov, Kun‐Huei Yeh, Soo-Jung Lee, Hong Sun, Hui Zhang Hit paper breakdown →	1999	683
17	Clusters of Replicons That Fire Simultaneously May Be Organized into Superloops DNA and Cell Biology ·Dimiter Kunnev, Lyuben Tsvetkov, Boyka Anachkova, George Russev	1997	8
18	Effect of mimosine on DNA synthesis in mammalian cells. PubMed ·Lyuben Tsvetkov, G. Russev, Boyka Anachkova	1997	17
19	Decreased Rates of Replicon Initiation in Mammalian Cells European Journal of Biochemistry ·Lyuben Tsvetkov, George Russev	1996	2

About Lyuben Tsvetkov

Lyuben Tsvetkov is a scholar working on Cell Biology, Oncology, Molecular Biology, Cancer Research and Hematology, having authored 19 papers that have together received 1.8k indexed citations. Recurring topics across this work include Cancer-related Molecular Pathways (10 papers), DNA Repair Mechanisms (10 papers), Microtubule and mitosis dynamics (7 papers), Ubiquitin and proteasome pathways (7 papers), Protein Degradation and Inhibitors (2 papers), Plant Genetic and Mutation Studies (2 papers), Genomics and Chromatin Dynamics (2 papers) and Carcinogens and Genotoxicity Assessment (2 papers). The work is most often cited by research in Oncology (1.1k citations), Cell Biology (426 citations), Molecular Biology (1.4k citations), Cancer Research (180 citations) and Immunology (194 citations). Lyuben Tsvetkov has collaborated with scholars based in United States, Bulgaria and France. Frequent co-authors include Hong Sun, Hui Zhang, Kun‐Huei Yeh, David F. Stern, Xingzhi Xu, Jia Li, Valia T. Mihaylova, Nadia J. Gavrilova, Ramanaiah Mamillapalli and Hong Wu. Their work appears in journals such as Cell Cycle, Current Biology, Journal of Biological Chemistry, Molecular Carcinogenesis and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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