Luke W. Koblan

12.9k total citations · 9 hit papers
19 papers, 8.0k citations indexed

About

Luke W. Koblan is a scholar working on Molecular Biology, Genetics and Cellular and Molecular Neuroscience. According to data from OpenAlex, Luke W. Koblan has authored 19 papers receiving a total of 8.0k indexed citations (citations by other indexed papers that have themselves been cited), including 18 papers in Molecular Biology, 4 papers in Genetics and 1 paper in Cellular and Molecular Neuroscience. Recurrent topics in Luke W. Koblan's work include CRISPR and Genetic Engineering (14 papers), RNA and protein synthesis mechanisms (8 papers) and RNA regulation and disease (5 papers). Luke W. Koblan is often cited by papers focused on CRISPR and Genetic Engineering (14 papers), RNA and protein synthesis mechanisms (8 papers) and RNA regulation and disease (5 papers). Luke W. Koblan collaborates with scholars based in United States, China and Switzerland. Luke W. Koblan's co-authors include David R. Liu, Andrew V. Anzalone, Jonathan M. Levy, Gregory A. Newby, Christopher Wilson, Aditya Raguram, Jessie R. Davis, Peter J. Chen, Peyton B. Randolph and Alexander A. Sousa and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Luke W. Koblan

19 papers receiving 7.8k citations

Hit Papers

Search-and-replace genome editing without double-strand b... 2017 2026 2020 2023 2019 2020 2018 2020 2017 500 1000 1.5k 2.0k 2.5k

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Luke W. Koblan United States 15 7.5k 2.3k 1.1k 626 439 19 8.0k
Gregory A. Newby United States 30 8.0k 1.1× 2.4k 1.1× 1.1k 1.0× 615 1.0× 436 1.0× 59 8.7k
Holly A. Rees United States 17 7.1k 1.0× 1.9k 0.8× 875 0.8× 679 1.1× 379 0.9× 18 7.5k
Michael S. Packer United States 14 8.4k 1.1× 2.3k 1.0× 1.3k 1.2× 748 1.2× 436 1.0× 18 9.0k
Aditya Raguram United States 19 6.6k 0.9× 1.9k 0.9× 1.2k 1.1× 531 0.8× 357 0.8× 23 7.2k
Luhan Yang United States 6 7.3k 1.0× 1.7k 0.7× 804 0.7× 556 0.9× 394 0.9× 8 8.0k
Sangsu Bae South Korea 34 6.5k 0.9× 1.4k 0.6× 1.2k 1.1× 664 1.1× 322 0.7× 112 7.1k
Andrew V. Anzalone United States 15 6.1k 0.8× 1.7k 0.7× 1.2k 1.1× 515 0.8× 346 0.8× 19 6.8k
Matthew H. Larson United States 14 8.2k 1.1× 2.0k 0.9× 658 0.6× 525 0.8× 376 0.9× 19 8.9k
Benjamin P. Kleinstiver United States 28 8.4k 1.1× 1.9k 0.8× 1.0k 0.9× 1.0k 1.6× 430 1.0× 66 8.7k
Nathalie T. Nguyen United States 17 6.3k 0.8× 1.4k 0.6× 703 0.6× 853 1.4× 458 1.0× 27 6.8k

Countries citing papers authored by Luke W. Koblan

Since Specialization
Citations

This map shows the geographic impact of Luke W. Koblan's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Luke W. Koblan with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Luke W. Koblan more than expected).

Fields of papers citing papers by Luke W. Koblan

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Luke W. Koblan. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Luke W. Koblan. The network helps show where Luke W. Koblan may publish in the future.

Co-authorship network of co-authors of Luke W. Koblan

This figure shows the co-authorship network connecting the top 25 collaborators of Luke W. Koblan. A scholar is included among the top collaborators of Luke W. Koblan based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Luke W. Koblan. Luke W. Koblan is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

19 of 19 papers shown
1.
Koblan, Luke W., Kathryn E. Yost, Pu Zheng, et al.. (2025). High-resolution spatial mapping of cell state and lineage dynamics in vivo with PEtracer. Science. 390(6770). eadx3800–eadx3800. 3 indexed citations
2.
Villiger, Lukas, Julia Joung, Luke W. Koblan, et al.. (2024). Author Correction: CRISPR technologies for genome, epigenome and transcriptome editing. Nature Reviews Molecular Cell Biology. 25(6). 510–510. 1 indexed citations
3.
Villiger, Lukas, Julia Joung, Luke W. Koblan, et al.. (2024). CRISPR technologies for genome, epigenome and transcriptome editing. Nature Reviews Molecular Cell Biology. 25(6). 464–487. 99 indexed citations breakdown →
4.
Koblan, Luke W., Mandana Arbab, Max W. Shen, et al.. (2021). Efficient C•G-to-G•C base editors developed using CRISPRi screens, target-library analysis, and machine learning. Nature Biotechnology. 39(11). 1414–1425. 155 indexed citations
5.
Hanna, Ruth E., Mudra Hegde, Christian Fagre, et al.. (2021). Massively parallel assessment of human variants with base editor screens. Cell. 184(4). 1064–1080.e20. 202 indexed citations breakdown →
6.
Anzalone, Andrew V., Xin D. Gao, Andrew T. Nelson, et al.. (2021). Programmable deletion, replacement, integration and inversion of large DNA sequences with twin prime editing. Nature Biotechnology. 40(5). 731–740. 376 indexed citations breakdown →
7.
Gete, Yantenew, Luke W. Koblan, Xiaojing Mao, et al.. (2021). Mechanisms of angiogenic incompetence in Hutchinson–Gilford progeria via downregulation of endothelial NOS. Aging Cell. 20(7). e13388–e13388. 21 indexed citations
8.
Koblan, Luke W., Michael R. Erdos, Leslie B. Gordon, et al.. (2021). Base editor treats progeria in mice. Nature. 4 indexed citations
9.
Richter, Michelle F., Kevin T. Zhao, Elliot O. Eton, et al.. (2020). Phage-assisted evolution of an adenine base editor with improved Cas domain compatibility and activity. Nature Biotechnology. 38(7). 883–891. 633 indexed citations breakdown →
10.
Anzalone, Andrew V., Luke W. Koblan, & David R. Liu. (2020). Genome editing with CRISPR–Cas nucleases, base editors, transposases and prime editors. Nature Biotechnology. 38(7). 824–844. 1475 indexed citations breakdown →
11.
Levy, Jonathan M., Wei-Hsi Yeh, Nachiket Pendse, et al.. (2020). Cytosine and adenine base editing of the brain, liver, retina, heart and skeletal muscle of mice via adeno-associated viruses. Nature Biomedical Engineering. 4(1). 97–110. 344 indexed citations breakdown →
12.
Song, Chun‐Qing, Tingting Jiang, Michelle F. Richter, et al.. (2019). Adenine base editing in an adult mouse model of tyrosinaemia. Nature Biomedical Engineering. 4(1). 125–130. 138 indexed citations
13.
Afeyan, Lena K., Vlado Dančík, Luke W. Koblan, et al.. (2019). High-resolution specificity profiling and off-target prediction for site-specific DNA recombinases. Nature Communications. 10(1). 1937–1937. 30 indexed citations
14.
Thuronyi, B W., Luke W. Koblan, Jonathan M. Levy, et al.. (2019). Continuous evolution of base editors with expanded target compatibility and improved activity. Nature Biotechnology. 37(9). 1070–1079. 240 indexed citations
15.
Anzalone, Andrew V., Peyton B. Randolph, Jessie R. Davis, et al.. (2019). Search-and-replace genome editing without double-strand breaks or donor DNA. Nature. 576(7785). 149–157. 2932 indexed citations breakdown →
16.
Koblan, Luke W., Jordan L. Doman, Christopher Wilson, et al.. (2018). Improving cytidine and adenine base editors by expression optimization and ancestral reconstruction. Nature Biotechnology. 36(9). 843–846. 662 indexed citations breakdown →
17.
Komor, Alexis C., Kevin T. Zhao, Michael S. Packer, et al.. (2017). Improved base excision repair inhibition and bacteriophage Mu Gam protein yields C:G-to-T:A base editors with higher efficiency and product purity. Science Advances. 3(8). eaao4774–eaao4774. 568 indexed citations breakdown →
18.
Koblan, Luke W., Dennis L. Buckley, Christopher J. Ott, et al.. (2016). Assessment of Bromodomain Target Engagement by a Series of BI2536 Analogues with Miniaturized BET‐BRET. ChemMedChem. 11(23). 2575–2581. 12 indexed citations
19.
Bachovchin, Daniel A., Luke W. Koblan, Wengen Wu, et al.. (2014). A high-throughput, multiplexed assay for superfamily-wide profiling of enzyme activity. Nature Chemical Biology. 10(8). 656–663. 60 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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