Holly A. Rees

12.4k total citations · 6 hit papers
18 papers, 7.5k citations indexed

About

Holly A. Rees is a scholar working on Molecular Biology, Epidemiology and Surgery. According to data from OpenAlex, Holly A. Rees has authored 18 papers receiving a total of 7.5k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Molecular Biology, 2 papers in Epidemiology and 1 paper in Surgery. Recurrent topics in Holly A. Rees's work include CRISPR and Genetic Engineering (14 papers), RNA regulation and disease (8 papers) and RNA and protein synthesis mechanisms (6 papers). Holly A. Rees is often cited by papers focused on CRISPR and Genetic Engineering (14 papers), RNA regulation and disease (8 papers) and RNA and protein synthesis mechanisms (6 papers). Holly A. Rees collaborates with scholars based in United States and United Kingdom. Holly A. Rees's co-authors include David R. Liu, Michael S. Packer, Alexis C. Komor, Nicole M. Gaudelli, David I. Bryson, Ahmed H. Badran, Xue Gao, Shannon M. Miller, Zhi Lin and Ning Sun and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nature Communications.

In The Last Decade

Holly A. Rees

18 papers receiving 7.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage

2017 2.8k citations Nicole M. Gaudelli, Alexis C. Komor et al. Nature profile →
Evolved Cas9 variants with broad PAM compatibility and high DNA specificity

2018 1.2k citations Johnny H. Hu, Shannon M. Miller et al. Nature profile →
Base editing: precision chemistry on the genome and transcriptome of living cells

2018 1.1k citations Holly A. Rees, David R. Liu Nature Reviews Genetics profile →
Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles

2016 540 citations Ming Wang, John A. Zuris et al. Proceedings of the National Academy of Sciences profile →
Directed evolution of adenine base editors with increased activity and therapeutic application

2020 341 citations Nicole M. Gaudelli, Dieter K. Lam et al. Nature Biotechnology profile →
Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery

2017 326 citations Holly A. Rees, Alexis C. Komor et al. Nature Communications profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Holly A. Rees United States	17	7.1k	1.9k	875	679	410	18	7.5k
Luke W. Koblan United States	15	7.5k 1.1×	2.3k 1.2×	1.1k 1.2×	626 0.9×	402 1.0×	19	8.0k
Luhan Yang United States	6	7.3k 1.0×	1.7k 0.9×	804 0.9×	556 0.8×	383 0.9×	8	8.0k
Gregory A. Newby United States	30	8.0k 1.1×	2.4k 1.3×	1.1k 1.2×	615 0.9×	330 0.8×	59	8.7k
Michael S. Packer United States	14	8.4k 1.2×	2.3k 1.2×	1.3k 1.4×	748 1.1×	532 1.3×	18	9.0k
Aditya Raguram United States	19	6.6k 0.9×	1.9k 1.0×	1.2k 1.3×	531 0.8×	311 0.8×	23	7.2k
Sangsu Bae South Korea	34	6.5k 0.9×	1.4k 0.7×	1.2k 1.4×	664 1.0×	419 1.0×	112	7.1k
Nathalie T. Nguyen United States	17	6.3k 0.9×	1.4k 0.7×	703 0.8×	853 1.3×	476 1.2×	27	6.8k
Matthew H. Larson United States	14	8.2k 1.2×	2.0k 1.0×	658 0.8×	525 0.8×	399 1.0×	19	8.9k
Thomas J. Cradick United States	20	5.9k 0.8×	1.4k 0.7×	721 0.8×	648 1.0×	359 0.9×	33	6.4k
Benjamin P. Kleinstiver United States	28	8.4k 1.2×	1.9k 1.0×	1.0k 1.2×	1.0k 1.5×	671 1.6×	66	8.7k

Countries citing papers authored by Holly A. Rees

Since Specialization

Citations

This map shows the geographic impact of Holly A. Rees's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Holly A. Rees with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Holly A. Rees more than expected).

Fields of papers citing papers by Holly A. Rees

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Holly A. Rees. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Holly A. Rees. The network helps show where Holly A. Rees may publish in the future.

Co-authorship network of co-authors of Holly A. Rees

This figure shows the co-authorship network connecting the top 25 collaborators of Holly A. Rees. A scholar is included among the top collaborators of Holly A. Rees based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Holly A. Rees. Holly A. Rees is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

Chu, S. Haihua, Michael S. Packer, Holly A. Rees, et al.. (2021). Rationally Designed Base Editors for Precise Editing of the Sickle Cell Disease Mutation. The CRISPR Journal. 4(2). 169–177. 55 indexed citations

Rees, Holly A., et al.. (2021). CRISPR-derived genome editing therapies: Progress from bench to bedside. Molecular Therapy. 29(11). 3125–3139. 12 indexed citations

Miller, Shannon M., Tina Wang, Peyton B. Randolph, et al.. (2020). Continuous evolution of SpCas9 variants compatible with non-G PAMs. Nature Biotechnology. 38(4). 471–481. 257 indexed citations

Yu, Yi, Thomas Leete, David A. Born, et al.. (2020). Cytosine base editors with minimized unguided DNA and RNA off-target events and high on-target activity. Nature Communications. 11(1). 2052–2052. 151 indexed citations

Gaudelli, Nicole M., Dieter K. Lam, Holly A. Rees, et al.. (2020). Directed evolution of adenine base editors with increased activity and therapeutic application. Nature Biotechnology. 38(7). 892–900. 341 indexed citations breakdown →

Rees, Holly A., Wei-Hsi Yeh, & David R. Liu. (2019). Development of hRad51–Cas9 nickase fusions that mediate HDR without double-stranded breaks. Nature Communications. 10(1). 2212–2212. 64 indexed citations

Rees, Holly A., Christopher Wilson, Jordan L. Doman, & David R. Liu. (2019). Analysis and minimization of cellular RNA editing by DNA adenine base editors. Science Advances. 5(5). eaax5717–eaax5717. 216 indexed citations

Aznarez, Isabel, Tomoki Nomakuchi, Jaclyn Tetenbaum-Novatt, et al.. (2018). Mechanism of Nonsense-Mediated mRNA Decay Stimulation by Splicing Factor SRSF1. Cell Reports. 23(7). 2186–2198. 55 indexed citations

Hu, Johnny H., Shannon M. Miller, Maarten H. Geurts, et al.. (2018). Evolved Cas9 variants with broad PAM compatibility and high DNA specificity. Nature. 556(7699). 57–63. 1155 indexed citations breakdown →

10.

Krishnan, Yamini, Holly A. Rees, Sieun Kim, et al.. (2018). Green fluorescent proteins engineered for cartilage-targeted drug delivery: Insights for transport into highly charged avascular tissues. Biomaterials. 183. 218–233. 54 indexed citations

11.

Yeh, Wei-Hsi, et al.. (2018). In vivo base editing of post-mitotic sensory cells. Nature Communications. 9(1). 2184–2184. 160 indexed citations

12.

Rees, Holly A. & David R. Liu. (2018). Base editing: precision chemistry on the genome and transcriptome of living cells. Nature Reviews Genetics. 19(12). 770–788. 1108 indexed citations breakdown →

13.

Rees, Holly A. & David R. Liu. (2018). Publisher Correction: Base editing: precision chemistry on the genome and transcriptome of living cells. Nature Reviews Genetics. 19(12). 801–801. 51 indexed citations

14.

Packer, Michael S., Holly A. Rees, & David R. Liu. (2017). Phage-assisted continuous evolution of proteases with altered substrate specificity. Nature Communications. 8(1). 956–956. 88 indexed citations

15.

Gaudelli, Nicole M., Alexis C. Komor, Holly A. Rees, et al.. (2017). Programmable base editing of A•T to G•C in genomic DNA without DNA cleavage. Nature. 551(7681). 464–471. 2789 indexed citations breakdown →

16.

Rees, Holly A., Alexis C. Komor, Wei-Hsi Yeh, et al.. (2017). Improving the DNA specificity and applicability of base editing through protein engineering and protein delivery. Nature Communications. 8(1). 15790–15790. 326 indexed citations breakdown →

17.

Wang, Ming, John A. Zuris, Fantao Meng, et al.. (2016). Efficient delivery of genome-editing proteins using bioreducible lipid nanoparticles. Proceedings of the National Academy of Sciences. 113(11). 2868–2873. 540 indexed citations breakdown →

18.

Marsh, Joseph A., Holly A. Rees, Sebastian E. Ahnert, & Sarah A. Teichmann. (2015). Structural and evolutionary versatility in protein complexes with uneven stoichiometry. Nature Communications. 6(1). 6394–6394. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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