Louis M. Luttrell

25.3k total citations · 17 hit papers
169 papers, 20.8k citations indexed

About

Louis M. Luttrell is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience and Cell Biology. According to data from OpenAlex, Louis M. Luttrell has authored 169 papers receiving a total of 20.8k indexed citations (citations by other indexed papers that have themselves been cited), including 148 papers in Molecular Biology, 42 papers in Cellular and Molecular Neuroscience and 14 papers in Cell Biology. Recurrent topics in Louis M. Luttrell's work include Receptor Mechanisms and Signaling (104 papers), Protein Kinase Regulation and GTPase Signaling (66 papers) and Neuropeptides and Animal Physiology (36 papers). Louis M. Luttrell is often cited by papers focused on Receptor Mechanisms and Signaling (104 papers), Protein Kinase Regulation and GTPase Signaling (66 papers) and Neuropeptides and Animal Physiology (36 papers). Louis M. Luttrell collaborates with scholars based in United States, Lebanon and Belgium. Louis M. Luttrell's co-authors include Robert J. Lefkowitz, Yehia Daaka, Deirdre K. Luttrell, Tim van Biesen, Brian E. Hawes, Stuart Maudsley, Kristen L. Pierce, Gregory J. Della Rocca, Seungkirl Ahn and William E. Miller and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Louis M. Luttrell

169 papers receiving 20.4k citations

Hit Papers

β-Arrestin-Dependent Form... 1994 2026 2004 2015 1999 1997 2002 2001 1999 400 800 1.2k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. β-Arrestin-Dependent Formation of β 2 Adrenergic Receptor-Src Protein Kinase Complexes
    1999 1.2k citations Louis M. Luttrell, Stephen S. G. Ferguson et al. profile →
  2. Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
    1997 1.1k citations Yehia Daaka, Louis M. Luttrell et al. profile →
  3. The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals
    2002 878 citations Louis M. Luttrell, Robert J. Lefkowitz Journal of Cell Science profile →
  4. Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
    2001 682 citations Louis M. Luttrell, William E. Miller et al. profile →
  5. Regulation of tyrosine kinase cascades by G-protein-coupled receptors
    1999 595 citations Louis M. Luttrell, Yehia Daaka et al. profile →
  6. Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2
    2003 547 citations Seungkirl Ahn, Sudha K. Shenoy et al. profile →
  7. Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
    1995 497 citations Deirdre K. Luttrell, Louis M. Luttrell et al. profile →
  8. Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
    1996 485 citations Louis M. Luttrell, Deirdre K. Luttrell et al. Journal of Biological Chemistry profile →
  9. Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase
    1998 481 citations Yehia Daaka, Louis M. Luttrell et al. Journal of Biological Chemistry profile →
  10. Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
    1997 416 citations Louis M. Luttrell, Gregory J. Della Rocca et al. Journal of Biological Chemistry profile →
  11. Ras-dependent Mitogen-activated Protein Kinase Activation by G Protein-coupled Receptors
    1997 408 citations Gregory J. Della Rocca, Yehia Daaka et al. Journal of Biological Chemistry profile →
  12. Distinct Pathways of Gi- and Gq-mediated Mitogen-activated Protein Kinase Activation
    1995 405 citations Louis M. Luttrell, Robert J. Lefkowitz et al. Journal of Biological Chemistry profile →
  13. Cellular expression of the carboxyl terminus of a G protein-coupled receptor kinase attenuates G beta gamma-mediated signaling.
    1994 376 citations Louis M. Luttrell, Robert J. Lefkowitz et al. Journal of Biological Chemistry profile →
  14. Mitogenic Signaling via G Protein-Coupled Receptors
    1996 375 citations Louis M. Luttrell, Robert J. Lefkowitz et al. profile →
  15. Distinct β-Arrestin- and G Protein-dependent Pathways for Parathyroid Hormone Receptor-stimulated ERK1/2 Activation
    2006 372 citations Diane Gesty‐Palmer, Éric Reiter et al. Journal of Biological Chemistry profile →
  16. Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
    1998 371 citations Louis M. Luttrell, Howard A. Rockman et al. profile →
  17. Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
    1996 338 citations Louis M. Luttrell, Robert J. Lefkowitz et al. Journal of Biological Chemistry profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Louis M. Luttrell United States 73 16.6k 7.2k 2.2k 2.1k 1.8k 169 20.8k
Jeffrey Benovic United States 94 23.8k 1.4× 13.5k 1.9× 2.3k 1.1× 3.2k 1.6× 2.8k 1.5× 290 28.8k
Richard T. Premont United States 64 11.4k 0.7× 5.2k 0.7× 1.1k 0.5× 2.9k 1.4× 1.4k 0.8× 166 15.3k
Toshiaki Katada Japan 69 13.1k 0.8× 3.5k 0.5× 1.3k 0.6× 3.7k 1.8× 1.7k 0.9× 300 18.1k
Ushio Kikkawa Japan 74 18.9k 1.1× 3.7k 0.5× 1.9k 0.9× 3.9k 1.9× 2.7k 1.5× 203 24.5k
Miles D. Houslay United Kingdom 88 19.8k 1.2× 4.4k 0.6× 1.6k 0.7× 1.7k 0.8× 3.4k 1.9× 414 25.6k
G. Stanley McKnight United States 76 10.9k 0.7× 3.8k 0.5× 1.1k 0.5× 1.3k 0.6× 1.6k 0.9× 164 16.8k
Sudha K. Shenoy United States 42 10.0k 0.6× 5.3k 0.7× 961 0.4× 1.1k 0.5× 908 0.5× 82 11.7k
Thomas Franke United States 36 11.8k 0.7× 1.9k 0.3× 2.4k 1.1× 1.6k 0.8× 2.2k 1.2× 49 17.6k
C. Peter Downes United Kingdom 77 19.3k 1.2× 3.7k 0.5× 1.9k 0.9× 5.5k 2.7× 2.9k 1.6× 196 26.5k
Vincent Giguère Canada 82 15.6k 0.9× 3.4k 0.5× 2.4k 1.1× 1.2k 0.6× 3.1k 1.7× 217 24.4k

Countries citing papers authored by Louis M. Luttrell

Since Specialization
Citations

This map shows the geographic impact of Louis M. Luttrell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Louis M. Luttrell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Louis M. Luttrell more than expected).

Fields of papers citing papers by Louis M. Luttrell

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Louis M. Luttrell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Louis M. Luttrell. The network helps show where Louis M. Luttrell may publish in the future.

Co-authorship network of co-authors of Louis M. Luttrell

This figure shows the co-authorship network connecting the top 25 collaborators of Louis M. Luttrell. A scholar is included among the top collaborators of Louis M. Luttrell based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Louis M. Luttrell. Louis M. Luttrell is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Elmansi, Ahmed M., Nada H. Eisa, Sudharsan Periyasamy‐Thandavan, et al.. (2022). DPP4-Truncated CXCL12 Alters CXCR4/ACKR3 Signaling, Osteogenic Cell Differentiation, Migration, and Senescence. ACS Pharmacology & Translational Science. 6(1). 22–39. 7 indexed citations
2.
Appleton, Kathryn M., Mi‐Hye Lee, Erik G. Strungs, et al.. (2019). Dissociation of β-Arrestin-Dependent Desensitization and Signaling Using 'Biased' Parathyroid Hormone Receptor Ligands. SSRN Electronic Journal. 1 indexed citations
3.
Ghosh, Eshan, Hemlata Dwivedi, Mithu Baidya, et al.. (2019). Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms. Cell Reports. 28(13). 3287–3299.e6. 42 indexed citations
4.
Gastel, Jaana van, Richard T. Premont, Louis M. Luttrell, et al.. (2018). GIT2—A keystone in ageing and age-related disease. Ageing Research Reviews. 43. 46–63. 25 indexed citations
5.
Luttrell, Louis M., Jialu Wang, Bianca Plouffe, et al.. (2018). Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11(549). 153 indexed citations
6.
Kendall, Ryan T., Mi‐Hye Lee, Katherine M. Robinson, et al.. (2014). Arrestin-dependent Angiotensin AT1 Receptor Signaling Regulates Akt and mTor-mediated Protein Synthesis. Journal of Biological Chemistry. 289(38). 26155–26166. 40 indexed citations
7.
Gesty‐Palmer, Diane, Ling Yuan, Bronwen Martin, et al.. (2013). β-Arrestin-Selective G Protein-Coupled Receptor Agonists Engender Unique Biological Efficacy in Vivo. Molecular Endocrinology. 27(2). 296–314. 49 indexed citations
8.
Luttrell, Louis M., et al.. (2013). Relationship between vitamin D status and incidence of vascular events in the Veterans Affairs Diabetes Trial. Atherosclerosis. 228(2). 502–507. 25 indexed citations
9.
Shenoy, Sudha K., Larry S. Barak, Kunhong Xiao, et al.. (2007). Ubiquitination of β-Arrestin Links Seven-transmembrane Receptor Endocytosis and ERK Activation. Journal of Biological Chemistry. 282(40). 29549–29562. 113 indexed citations
10.
El‐Shewy, Hesham M., et al.. (2006). Constitutive ERK1/2 Activation by a Chimeric Neurokinin 1 Receptor-β-Arrestin1 Fusion Protein. Journal of Biological Chemistry. 281(28). 19346–19357. 32 indexed citations
11.
Luttrell, Louis M.. (2005). Composition and Function of G Protein-Coupled Receptor Signalsomes Controlling Mitogen-Activated Protein Kinase Activity. Journal of Molecular Neuroscience. 26(2-3). 253–264. 87 indexed citations
12.
Luttrell, Louis M.. (2003). 'Location, location, location': activation and targeting of MAP kinases by G protein-coupled receptors. Journal of Molecular Endocrinology. 30(2). 117–126. 110 indexed citations
13.
Luttrell, Deirdre K. & Louis M. Luttrell. (2003). Signaling in Time and Space: G Protein-Coupled Receptors and Mitogen-Activated Protein Kinases. Assay and Drug Development Technologies. 1(2). 327–338. 51 indexed citations
14.
Luttrell, Louis M.. (2002). Big G, Little G. Molecular Cell. 9(6). 1152–1154. 3 indexed citations
15.
Luttrell, Louis M. & Robert J. Lefkowitz. (2002). The role of β-arrestins in the termination and transduction of G-protein-coupled receptor signals. Journal of Cell Science. 115(3). 455–465. 878 indexed citations breakdown →
16.
Tohgo, Akira, et al.. (2002). β-Arrestin Scaffolding of the ERK Cascade Enhances Cytosolic ERK Activity but Inhibits ERK-mediated Transcription following Angiotensin AT1a Receptor Stimulation. Journal of Biological Chemistry. 277(11). 9429–9436. 315 indexed citations
17.
Guo, Chuanhai, Louis M. Luttrell, & David T. Price. (2000). MITOGENIC SIGNALING IN ANDROGEN SENSITIVE AND INSENSITIVE PROSTATE CANCER CELL LINES. The Journal of Urology. 163(3). 1027–1032. 63 indexed citations
18.
Maudsley, Stuart, Kristen L. Pierce, A.M. Zamah, et al.. (2000). The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor. Journal of Biological Chemistry. 275(13). 9572–9580. 357 indexed citations
19.
Daaka, Yehia, Louis M. Luttrell, Seungkirl Ahn, et al.. (1998). Essential Role for G Protein-coupled Receptor Endocytosis in the Activation of Mitogen-activated Protein Kinase. Journal of Biological Chemistry. 273(2). 685–688. 481 indexed citations breakdown →
20.
Luttrell, Louis M., Souha S. Kanj, G. Ralph Corey, et al.. (1994). Mycoplasma hominis Septic Arthritis: Two Case Reports and Review. Clinical Infectious Diseases. 19(6). 1067–1070. 38 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Breakdown of academic impact, for papers by Jeffrey Benovic Breakdown of academic impact, for papers by Richard T. Premont Breakdown of academic impact, for papers by Toshiaki Katada Breakdown of academic impact, for papers by Ushio Kikkawa Breakdown of academic impact, for papers by Miles D. Houslay Breakdown of academic impact, for papers by G. Stanley McKnight Breakdown of academic impact, for papers by Sudha K. Shenoy Breakdown of academic impact, for papers by Thomas Franke Breakdown of academic impact, for papers by C. Peter Downes Breakdown of academic impact, for papers by Vincent Giguère
Rankless by CCL
2026