Lauge Schäffer

3.9k citations

29 papers · 3.1k indexed · 2 hit papers · h-index 24

Impact in

Endocrinology, Diabetes and Metabolism top 0.5%
- Diabetes Treatment and Management
- Growth Hormone and Insulin-like Growth Factors
Endocrine and Autonomic Systems top 2%
- Regulation of Appetite and Obesity

Papers in

Endocrinology, Diabetes and Metabolism 14
- Diabetes Treatment and Management 7
- Growth Hormone and Insulin-like Growth Factors 6
Endocrine and Autonomic Systems 3
- Regulation of Appetite and Obesity 3

Co-authors: Lotte Bjerre Knudsen Asser S. Andersen Jacob Hecksher‐Sørensen Kirsten Raun Jane C. Spetzler Thomas Kruse Steffen Reedtz‐Runge Anna Secher
Journals: Journal of Biological Chemistry (9 papers)Journal of Medicinal Chemistry (2 papers)Experimental and Clinical Endocrinology & Diabetes (2 papers)European Journal of Biochemistry (1 paper)Diabetes (1 paper)
Partner nations: Denmark United States United Kingdom

In The Last Decade

Lauge Schäffer

28 papers receiving 3.0k citations

Hit Papers

align trajectories log scale

Discovery of the Once-Weekly Glucagon-Like Peptide-1 (GLP-1) Analogue Semaglutide 2015 · 736 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 Journal of Medicinal Chemistry
2014 Journal of Clinical Investigation

Peers

Countries citing papers authored by Lauge Schäffer

Since Specialization

Citations

This map shows the geographic impact of Lauge Schäffer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lauge Schäffer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lauge Schäffer more than expected).

Fields of papers citing papers by Lauge Schäffer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lauge Schäffer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lauge Schäffer. The network helps show where Lauge Schäffer may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lauge Schäffer, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lauge Schäffer Line = papers co-authored together Lauge Schäffer links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Development of Cagrilintide, a Long-Acting Amylin Analogue Journal of Medicinal Chemistry ·Thomas Kruse, Jakob Lerche Hansen, Kirsten Dahl, Lauge Schäffer, D. G. Hall, Christian Poulsen, Morten Schlein, Ann Maria Kruse Hansen, Claus Jeppesen, Charlotta Dornonville de la Cour, Trine Ryberg Clausen, Eva Johansson, Simone Fulle, Rikke Bjerring Skyggebjerg, Kirsten Raun	2021	76
2	Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice Neuropharmacology ·D Wind, Linu M. John, Jens Lykkesfeldt, Kirsten Raun, Tine Glendorf, Lauge Schäffer, Sofia Lundh, Anna Secher, Thomas A. Lutz, Christelle Le Foll	2020	27
3	Type II Turn of Receptor-bound Salmon Calcitonin Revealed by X-ray Crystallography Journal of Biological Chemistry ·Eva Johansson, Jakob Lerche Hansen, Ann Maria Kruse Hansen, Allan C. Shaw, Peter B. Becker, Lauge Schäffer, Steffen Reedtz‐Runge	2016	35
4	Beta cell specific probing with fluorescent exendin-4 is progressively reduced in type 2 diabetic mouse models Islets ·Tyler Kendon, Lauge Schäffer, Morten G. Rasch, Jacob Hecksher‐Sørensen, Jonas Ahnfelt‐Rønne	2015	11
5	The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss Journal of Clinical Investigation ·Anna Secher, Jacob Jelsing, Arian F. Baquero, Jacob Hecksher‐Sørensen, Michael A. Cowley, Louise S. Dalbøge, Gitte Hansen, Kevin L. Grove, Charles Pyke, Kirsten Raun, Lauge Schäffer, Mads Tang‐Christensen, Saurabh Verma, Brent M. Witgen, Niels Vrang, Lotte Bjerre Knudsen Hit paper breakdown →	2014	702
6	Real-time trafficking and signaling of the glucagon-like peptide-1 receptor Molecular and Cellular Endocrinology ·Christopher Siow, Pernille Wismann, Christina Rye Underwood, Nikolaj Kulahin, Helle K. Iversen, 吉晴穴田, Lauge Schäffer, Tyler Kendon, Jacob Hecksher‐Sørensen, M. Yahyaoui, Jesper Mosolff Mathiesen, Hans Bräuner‐Osborne, Jennifer L. Whistler, 运勃 Yun Bo, Maria Waldhoer	2013	125
7	Agonism and Antagonism at the Insulin Receptor PLoS ONE ·Ili Ramli, Bo F. Hansen, Z. Ivics, Thomas Åskov Pedersen, Najam Usama, Lauge Schäffer, Blagoy Blagoev, Martin B. Oleksiewicz, Vladislav V. Kiselyov, Pierre De Meyts	2012	44
8	A novel high-affinity peptide antagonist to the insulin receptor Biochemical and Biophysical Research Communications ·Lauge Schäffer, Christian L. Brand, D. Navaneethan, Ulla Ribel, Allan C. Shaw, Rita Slaaby, Jeppe Sturis	2008	130
9	Activation of the Insulin Receptor by Insulin and a Synthetic Peptide Leads to Divergent Metabolic and Mitogenic Signaling and Responses Journal of Biological Chemistry ·Maja Jensen, Bente Langvad Hansen, Pierre De Meyts, Lauge Schäffer, Birgitte Ursø	2007	68
10	Hybrid Receptors Formed by Insulin Receptor (IR) and Insulin-like Growth Factor I Receptor (IGF-IR) Have Low Insulin and High IGF-1 Affinity Irrespective of the IR Splice Variant Journal of Biological Chemistry ·Rita Slaaby, Lauge Schäffer, Inger Lautrup-Larsen, Asser S. Andersen, Allan C. Shaw, Ida Stenfeldt Mathiasen, Jakob Brandt	2006	157
11	Insulins with built-in glucose sensors for glucose responsive insulin release Journal of Peptide Science ·Thomas Høeg-Jensen, Othmar Plöckinger, Svend Havelund, Lauge Schäffer, Per Balschmidt, Inge Jonassen, Per Vedsø, Preben H. Olesen, Jan Markussen	2004	34
12	Peptides Identify the Critical Hotspots Involved in the Biological Activation of the Insulin Receptor Journal of Biological Chemistry ·Renuka Pillutla, Ku-chuan Hsiao, James R. Beasley, Jakob Brandt, Søren Østergaard, Per Hansen, Jane C. Spetzler, Gillian M. Danielsen, Asser S. Andersen, R E Brissette, Michael Lennick, Paul W. Fletcher, Arthur J. Blume, Lauge Schäffer, Neil I. Goldstein	2002	74
13	Purification, Characterization, and Biological Activity of Insulins from the Spotted Dogfish, Scyliorhinus canicula, and the Hammerhead Shark, Sphyrna lewini General and Comparative Endocrinology ·W. Gary Anderson, Mohamed F. Ali, Ingibjörg Eir Einarsdóttir, Lauge Schäffer, Neil Hazon, J. Michael Conlon	2002	24
14	A New Secreted Insect Protein Belonging to the Immunoglobulin Superfamily Binds Insulin and Related Peptides and Inhibits Their Activities Journal of Biological Chemistry ·Asser S. Andersen, Per Hansen, Lauge Schäffer, Claus Kristensen	2000	56
15	Insulin aspart: a novel rapid-acting human insulin analogue Expert Opinion on Investigational Drugs ·Steen Gammeltoft, Bo F. Hansen, Denísio Liberato, Anders Lindholm, Lauge Schäffer, Thomas Trüb, Anthony D. Dayan, Peter Kurtzhals	1999	29
16	Identification of Common Ligand Binding Determinants of the Insulin and Insulin-like Growth Factor 1 Receptors Journal of Biological Chemistry ·Dennis C. Mynarcik, Paul F. Williams, Lauge Schäffer, Muhamad Azrul Amin Yahaya, Jonathan Whittaker	1997	72
17	Alanine Scanning Mutagenesis of Insulin Journal of Biological Chemistry ·Claus Kristensen, Thomas Kjeldsen, Finn C. Wiberg, Lauge Schäffer, Morten Hach, Svend Havelund, Joseph Bass, Donald F. Steiner, Asser S. Andersen	1997	180
18	Analog Binding Properties of Insulin Receptor Mutants Journal of Biological Chemistry ·Dennis C. Mynarcik, Paul F. Williams, Lauge Schäffer, Muhamad Azrul Amin Yahaya, Jonathan Whittaker	1997	27
19	A model for insulin binding to the insulin receptor European Journal of Biochemistry ·Lauge Schäffer	1994	173
20	Development of an optimized refolding process for recombinant Ala–Glu–IGF-1 Protein Engineering Design and Selection ·Kim R. Hejnæs, 豊一郎信貴, Thomas Henning, Chao Li, Thi Thuy Linh Trinh, Johannes Thomsen, Lauge Schäffer, Axel Wollmer, Lars Skriver	1992	23

About Lauge Schäffer

Lauge Schäffer is a scholar working on Endocrinology, Diabetes and Metabolism, Endocrine and Autonomic Systems, Surgery, Molecular Biology and Genetics, having authored 29 papers that have together received 3.1k indexed citations. Recurring topics across this work include Pancreatic function and diabetes (16 papers), Metabolism, Diabetes, and Cancer (11 papers), Diabetes Treatment and Management (7 papers), Growth Hormone and Insulin-like Growth Factors (6 papers), Receptor Mechanisms and Signaling (6 papers), Diabetes and associated disorders (4 papers), Chemical Synthesis and Analysis (3 papers) and Regulation of Appetite and Obesity (3 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (1.4k citations), Endocrine and Autonomic Systems (387 citations), Molecular Biology (1.8k citations), Cellular and Molecular Neuroscience (434 citations) and Pharmacology (324 citations). Lauge Schäffer has collaborated with scholars based in Denmark, United States and United Kingdom. Frequent co-authors include Lotte Bjerre Knudsen, Asser S. Andersen, Jacob Hecksher‐Sørensen, Kirsten Raun, Jane C. Spetzler, Thomas Kruse, Steffen Reedtz‐Runge, Anna Secher, Allan C. Shaw and Claus Kristensen. Their work appears in journals such as Journal of Biological Chemistry, Journal of Medicinal Chemistry, Experimental and Clinical Endocrinology & Diabetes, European Journal of Biochemistry and Diabetes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact