Kirk Chu

2.0k citations

18 papers · 1.5k indexed · 1 hit paper · h-index 14

Co-authors: Mark A. Kay Leszek Lisowski Jianpeng Xu Feijie ZhangYue ZhangSean Nygaard Ian E. Alexander Hak Kyun Kim
Topics: Virus-based gene therapy research (8 papers)Viral Infectious Diseases and Gene Expression in Insects (5 papers)RNA Interference and Gene Delivery (4 papers)
Cited by: Cancer Research Genetics Molecular Biology
Journals: Nature Nucleic Acids Research Journal of Biological Chemistry
Partner nations: United States Australia China

In The Last Decade

Kirk Chu

18 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

A transfer-RNA-derived small RNA regulates ribosome biogenesis

2017 405 citations Hak Kyun Kim, Gabriele Fuchs et al. Nature profile →

Peers

Countries citing papers authored by Kirk Chu

Since Specialization

Citations

This map shows the geographic impact of Kirk Chu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kirk Chu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kirk Chu more than expected).

Fields of papers citing papers by Kirk Chu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kirk Chu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kirk Chu. The network helps show where Kirk Chu may publish in the future.

Co-authorship network of co-authors of Kirk Chu

This figure shows the co-authorship network connecting the top 25 collaborators of Kirk Chu. A scholar is included among the top collaborators of Kirk Chu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kirk Chu. Kirk Chu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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18 of 18 papers shown

#	Work	Indexed citations
1	A tRNA-Derived Small RNA Regulates Ribosomal Protein S28 Protein Levels after Translation Initiation in Humans and Mice 2019 ·Cell Reports ·Hak Kyun Kim,Jianpeng Xu,Kirk Chu,(unknown),(unknown),Pan Li,Paul N. Valdmanis,Qiangfeng Cliff Zhang,Mark A. Kay	77
2	miR-122 removal in the liver activates imprinted microRNAs and enables more effective microRNA-mediated gene repression 2018 ·Nature Communications ·Paul N. Valdmanis,Hak Kyun Kim,Kirk Chu,Feijie Zhang,Jianpeng Xu,Elizabeth M. Munding,Jia Shen,Mark A. Kay	57
3	Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity 2017 ·Molecular Therapy ·Nicole K. Paulk,Katja Pekrun,Erhua Zhu,Sean Nygaard,(unknown),Jianpeng Xu,Kirk Chu,(unknown),(unknown),Annelise Haft,Yue Zhang,Feijie Zhang,(unknown),(unknown),(unknown),Amit C. Nathwani,(unknown),Markus Grompe,Ian E. Alexander,Leszek Lisowski,Mark A. Kay	139
4	A transfer-RNA-derived small RNA regulates ribosome biogenesisbreakdown → 2017 ·Nature ·Hak Kyun Kim,Gabriele Fuchs,Shengchun Wang,Wei Wei,Yue Zhang,(unknown),Biswajoy Roy‐Chaudhuri,Pan Li,Jianpeng Xu,Kirk Chu,Feijie Zhang,Mei‐Sze Chua,Samuel So,Qiangfeng Cliff Zhang,Peter Sarnow,Mark A. Kay	405
5	A 5′ Noncoding Exon Containing Engineered Intron Enhances Transgene Expression from Recombinant AAV Vectors in vivo 2016 ·Human Gene Therapy ·Jiamiao Lu,James A. Williams,Jeremy Luke,Feijie Zhang,Kirk Chu,Mark A. Kay	20
6	RNA interference–induced hepatotoxicity results from loss of the first synthesized isoform of microRNA-122 in mice 2016 ·Nature Medicine ·Paul N. Valdmanis,Shuo Gu,Kirk Chu,Lan Jin,Feijie Zhang,Elizabeth M. Munding,Yue Zhang,Yong Huang,Huban Kutay,Kalpana Ghoshal,Leszek Lisowski,Mark A. Kay	27
7	262. Directed Evolution of Improved AAV Capsids for the Ideal Human Liver Vector–Can Human Liver Tropism and Human Immune Evasion Be Achieved? 2015 ·Molecular Therapy ·Nicole K. Paulk,Katja Pekrun,Leszek Lisowski,Yue Zhang,Kirk Chu,Mark A. Kay	1
8	Somatic Correction of Junctional Epidermolysis Bullosa by a Highly Recombinogenic AAV Variant 2014 ·Molecular Therapy ·Sandra P. Melo,Leszek Lisowski,Elizaveta Bashkirova,Hanson H. Zhen,Kirk Chu,Douglas R. Keene,M. Peter Marinkovich,Mark A. Kay,Anthony E. Oro	51
9	Selection and evaluation of clinically relevant AAV variants in a xenograft liver model 2013 ·Nature ·Leszek Lisowski,Allison Dane,Kirk Chu,Yue Zhang,Sharon C. Cunningham,Elizabeth M. Wilson,Sean Nygaard,Markus Grompe,Ian E. Alexander,Mark A. Kay	344
10	Cellular Localization and Characterization of Cytosolic Binding Partners for Gla Domain-containing Proteins PRRG4 and PRRG2 2013 ·Journal of Biological Chemistry ·Mustafa N. Yazicioglu,(unknown),Kirk Chu,Fayaz R. Khazi,Samuel L. Murphy,Heshu Huang,Paris Margaritis,Katherine A. High	13
11	The anti-genomic (negative) strand of Hepatitis C Virus is not targetable by shRNA 2013 ·Nucleic Acids Research ·Leszek Lisowski,Menashe Elazar,Kirk Chu,Jeffrey S. Glenn,Mark A. Kay	11
12	A concept of eliminating nonhomologous recombination for scalable and safe AAV vector generation for human gene therapy 2013 ·Nucleic Acids Research ·Biao Dong,Andrea R. Moore,Jihong Dai,Sean Roberts,Kirk Chu,Philipp Kapranov,Bernard Moss,Weidong Xiao	24
13	Transmembrane Gla Protein 4 as a Novel Modulator of ERK2. 2006 ·Blood ·Fayaz R. Khazi,Kirk Chu,Katherine A. High	1
14	Risk and Prevention of Anti-factor IX Formation in AAV-Mediated Gene Transfer in the Context of a Large Deletion of F9 2001 ·Molecular Therapy ·Paul Fields,Valder R. Arruda,Elina Armstrong,Kirk Chu,Federico Mingozzi,J. Nathan Hagstrom,Roland W. Herzog,Katherine A. High	107
15	Posttranslational modifications of recombinant myotube-synthesized human factor IX 2001 ·Blood ·Valder R. Arruda,(unknown),Jeffrey S. Deitch,Terry Heiman‐Patterson,Rodney M. Camire,Kirk Chu,Paul Fields,Roland W. Herzog,Linda B. Couto,Peter J. Larson,Katherine A. High	95
16	Regulation of human coagulation factor X gene expression by GATA-4 and the Sp family of transcription factors 2001 ·Blood ·Hsiao-Ling Hung,Eleanor S. Pollak,(unknown),Valder R. Arruda,Kirk Chu,Katherine A. High	20
17	Genomic Sequence and Transcription Start Site for the Human γ-Glutamyl Carboxylase 1997 ·Blood ·(unknown),Darrel W. Stafford,(unknown),(unknown),Katherine A. High,Kirk Chu,Beatriz Sánchez-Vega,Jesús Solera	46
18	Activation-dependent Exposure of the Inter-EGF Sequence Leu83-Leu88 in Factor Xa Mediates Ligand Binding to Effector Cell Protease Receptor-1 1997 ·Journal of Biological Chemistry ·Grazia Ambrosini,Janet Plescia,Kirk Chu,Katherine A. High,Dario C. Altieri	27

About Kirk Chu

Kirk Chu is a scholar working on Genetics, Molecular Biology and Genetics, having authored 18 papers that have together received 1.5k indexed citations. Recurring topics across this work include Virus-based gene therapy research (8 papers), Viral Infectious Diseases and Gene Expression in Insects (5 papers) and RNA Interference and Gene Delivery (4 papers). The work is most often cited by research in Cancer Research (362 citations), Genetics (612 citations) and Molecular Biology (1.1k citations). Kirk Chu has collaborated with scholars based in United States, Australia and China. Frequent co-authors include Mark A. Kay, Leszek Lisowski, Jianpeng Xu, Feijie Zhang, Yue Zhang, Sean Nygaard, Ian E. Alexander, Hak Kyun Kim, Markus Grompe and Katherine A. High. Their work appears in journals such as Nature, Nucleic Acids Research and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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