Kazuhiko Iwase

510 citations

12 papers · 427 indexed · h-index 11

Pharmaceutical Science top 5%
Organic Chemistry top 10%
- Chemical synthesis and alkaloids 2
- Synthesis and biological activity 1
Pharmacology
- Cholinesterase and Neurodegenerative Diseases 5
Process Chemistry and Technology
Computational Theory and Mathematics top 10%
Molecular Biology
- Phosphodiesterase function and regulation 6
- Cancer therapeutics and mechanisms 2
- Chemical Synthesis and Analysis 1
Immunology
- Mast cells and histamine 2
Filtration and Separation
- Chemical and Physical Properties in Aqueous Solutions 1

Co-authors: M. Hosaka Y. Asahina Takayoshi Ishizaki Shuichi Hirono Yasushi Kohno David R. Adams Tetsuya Kishi Tokutaro Yasue
Cited by: Pharmaceutical Science Organic Chemistry Pharmacology
Journals: Bioorganic & Medicinal Chemistry Letters (6 papers)Journal of Medicinal Chemistry (2 papers)Chemical and Pharmaceutical Bulletin (1 paper)
Partner nations: United Kingdom Japan United States

In The Last Decade

Kazuhiko Iwase

12 papers receiving 410 citations

Peers

Countries citing papers authored by Kazuhiko Iwase

Since Specialization

Citations

This map shows the geographic impact of Kazuhiko Iwase's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kazuhiko Iwase with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kazuhiko Iwase more than expected).

Fields of papers citing papers by Kazuhiko Iwase

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kazuhiko Iwase. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kazuhiko Iwase. The network helps show where Kazuhiko Iwase may publish in the future.

Co-authorship network

The 24 scholars most cited alongside Kazuhiko Iwase, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Kazuhiko Iwase Line = papers co-authored together Kazuhiko Iwase links everyone, so they are left out of the graph.

All Works

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12 of 12 papers shown

#	Work
1	Phosphodiesterase inhibitors. Part 6: Design, synthesis, and structure–activity relationships of PDE4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory activity Bioorganic & Medicinal Chemistry Letters ·Akihiko Kojima,J.J.A. Haagensen,Tatsunobu Sumiya,Koji Ochiai,Kazuhiko Iwase,Tetsuya Kishi,Basima Taresh Dawood,Yuichi Yageta,Tokutaro Yasue,Yasushi Kohno	2013	28
2	Phosphodiesterase inhibitors. Part 4: Design, synthesis and structure-activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-4,4-dimethylpyrazolones Bioorganic & Medicinal Chemistry Letters ·Koji Ochiai,J.J.A. Haagensen,Akihiko Kojima,A. V. Biryukov,N Ando,Kazuhiko Iwase,Tetsuya Kishi,Basima Taresh Dawood,Yuichi Yageta,Tokutaro Yasue,David R. Adams,Yasushi Kohno	2012	24
3	Phosphodiesterase inhibitors. Part 3: Design, synthesis and structure–activity relationships of dual PDE3/4-inhibitory fused bicyclic heteroaromatic-dihydropyridazinones with anti-inflammatory and bronchodilatory activity Bioorganic & Medicinal Chemistry ·Koji Ochiai,J.J.A. Haagensen,A. V. Biryukov,Akihiko Kojima,Kazuhiko Iwase,Tetsuya Kishi,Kazunori Fukuchi,Tokutaro Yasue,David R. Adams,Luca Roatta,Zhong‐Tao Jiang,Yasushi Kohno	2012	42
4	Phosphodiesterase inhibitors. Part 5: Hybrid PDE3/4 inhibitors as dual bronchorelaxant/anti-inflammatory agents for inhaled administration Bioorganic & Medicinal Chemistry Letters ·Koji Ochiai,J.J.A. Haagensen,Akihiko Kojima,A. V. Biryukov,Kazuhiko Iwase,Tetsuya Kishi,Basima Taresh Dawood,Yuichi Yageta,Tokutaro Yasue,David R. Adams,Yasushi Kohno	2012	31
5	Phosphodiesterase inhibitors. Part 2: Design, synthesis, and structure–activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity Bioorganic & Medicinal Chemistry Letters ·Koji Ochiai,N Ando,Kazuhiko Iwase,Tetsuya Kishi,Kazunori Fukuchi,Basima Taresh Dawood,Phatthraporn Termvoratham,Tokutaro Yasue,David R. Adams,Yasushi Kohno	2011	27
6	Phosphodiesterase inhibitors. Part 1: Synthesis and structure–activity relationships of pyrazolopyridine–pyridazinone PDE inhibitors developed from ibudilast Bioorganic & Medicinal Chemistry Letters ·Luca Roatta,Asai,Zhong‐Tao Jiang,Karen Johnston,Keith M. Morgan,Georgina M. Rosair,Kazuhiko Iwase,Yasushi Kohno,David R. Adams	2011	32
7	Synthesis and Antibacterial Activity of 1-(2-Fluorovinyl)-7-substituted-4-quinolone-3-carboxylic Acid Derivatives, Conformationally Restricted Analogues of Fleroxacin Journal of Medicinal Chemistry ·Y. Asahina,Kazuhiko Iwase,زیبا علیجانی,M. Hosaka,Takayoshi Ishizaki	2005	91
8	Synthesis and Antibacterial Activity of the 4-Quinolone-3-carboxylic Acid Derivatives Having a Trifluoromethyl Group as a Novel N-1 Substituent Journal of Medicinal Chemistry ·Y. Asahina,Lisa Zundel,Kazuhiko Iwase,زیبا علیجانی,M. Hosaka,Takayoshi Ishizaki	2005	58
9	Novel nikkomycin analogues: inhibitors of the fungal cell wall biosynthesis enzyme chitin synthase Bioorganic & Medicinal Chemistry Letters ·陈燕静,S.St Ft. Dwi Rosella K,Kazuhiko Iwase,Osamu Sugimoto,朱广军,Akira Matsuda	2000	31
10	Estimation of active conformations of drugs by a new molecular superposing procedure Journal of Computer-Aided Molecular Design ·Kazuhiko Iwase,Shuichi Hirono	1999	35
11	Estimation of hydrophobicity based on the solvent-accessible surface area of molecules. Chemical and Pharmaceutical Bulletin ·Kazuhiko Iwase,Katsuichiro Komatsu,Shuichi Hirono,Setsuko Nakagawa,IKUO MORIGUCHI	1985	26
12	Intermolecular rearrangement of N-acyltriacanthine. PubMed ·Michiko Miyaki,Kazuhiko Iwase,Isabelle Rachel Casta	1966	2

About Kazuhiko Iwase

Kazuhiko Iwase is a scholar working on Filtration and Separation, Pharmacology and Molecular Medicine, having authored 12 papers that have together received 427 indexed citations. Recurring topics across this work include Phosphodiesterase function and regulation (6 papers), Cholinesterase and Neurodegenerative Diseases (5 papers), Cancer therapeutics and mechanisms (2 papers), Mast cells and histamine (2 papers), Chemical synthesis and alkaloids (2 papers), Chemical Synthesis and Analysis (1 paper), Synthesis and biological activity (1 paper) and Chemical and Physical Properties in Aqueous Solutions (1 paper). The work is most often cited by research in Pharmaceutical Science (101 citations), Organic Chemistry (246 citations) and Pharmacology (90 citations). Kazuhiko Iwase has collaborated with scholars based in United Kingdom, Japan and United States. Frequent co-authors include M. Hosaka, Y. Asahina, Takayoshi Ishizaki, Shuichi Hirono, Yasushi Kohno, David R. Adams, Tetsuya Kishi, Tokutaro Yasue, Koji Ochiai and Akihiko Kojima. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Journal of Medicinal Chemistry, Chemical and Pharmaceutical Bulletin, Bioorganic & Medicinal Chemistry and Journal of Computer-Aided Molecular Design.

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