Karl Syson

507 citations

12 papers · 370 indexed · h-index 10

Impact in

Biotechnology top 5%
- Enzyme Production and Characterization
Infectious Diseases
- Tuberculosis Research and Epidemiology

Papers in ⓘ

Molecular Biology 8
- Biochemical and Molecular Research 7
Organic Chemistry 6
- Carbohydrate Chemistry and Synthesis 6

Co-authors: Stephen Bornemann (12 shared papers)Rainer Kalscheuer (6 shared papers)William R. Jacobs (3 shared papers)Veeraraghavan Usha (1 shared paper)Karolin Biermann (1 shared paper)Zhen Liu (1 shared paper)James C. Sacchettini (1 shared paper)Gurdyal S. Besra (1 shared paper)
Journals: Journal of Biological Chemistry (3 papers)PLoS Pathogens (2 papers)Biochemistry (2 papers)Biochimica et Biophysica Acta (BBA) - General Subjects (2 papers)Nature Chemical Biology (1 paper)
Partner nations: United Kingdom Germany United States

In The Last Decade

Karl Syson

12 papers receiving 367 citations

Peers

Countries citing papers authored by Karl Syson

Since Specialization

Citations

This map shows the geographic impact of Karl Syson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karl Syson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karl Syson more than expected).

Fields of papers citing papers by Karl Syson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karl Syson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karl Syson. The network helps show where Karl Syson may publish in the future.

Co-authors

The 25 scholars most cited alongside Karl Syson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Karl Syson Line = papers co-authored together Karl Syson links everyone, so they are left out of the graph.

All Works

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12 of 12 papers shown

#	Work
1	Self-poisoning of Mycobacterium tuberculosis by targeting GlgE in an α-glucan pathway Nature Chemical Biology ·Rainer Kalscheuer, Karl Syson, Veeraraghavan Usha, Brian Weinrick, Karolin Biermann, Zhen Liu, James C. Sacchettini, Gurdyal S. Besra, Stephen Bornemann, William R. Jacobs	2010	120
2	Structure of Streptomyces Maltosyltransferase GlgE, a Homologue of a Genetically Validated Anti-tuberculosis Target Journal of Biological Chemistry ·Karl Syson, Clare E. M. Stevenson, Martin Rejzek, Shirley A. Fairhurst, A. Nair, Celia J. Bruton, Robert A. Field, Keith Chater, David M. Lawson, Stephen Bornemann	2011	47
3	Metabolic Network for the Biosynthesis of Intra- and Extracellular α-Glucans Required for Virulence of Mycobacterium tuberculosis PLoS Pathogens ·Hendrik Koliwer‐Brandl, Karl Syson, Robert van de Weerd, Govind Chandra, Ben J. Appelmelk, Marina Alber, Thomas R. Ioerger, William R. Jacobs, Jeroen Geurtsen, Stephen Bornemann, Rainer Kalscheuer	2016	38
4	Assembly of α-Glucan by GlgE and GlgB in Mycobacteria and Streptomycetes Biochemistry ·Abdul Rashid, Sibyl F. D. Batey, Karl Syson, Hendrik Koliwer‐Brandl, Farzana Miah, J. Elaine Barclay, Kim Findlay, Karol P. Nartowski, Yaroslav Z. Khimyak, Rainer Kalscheuer, Stephen Bornemann	2016	29
5	Trehalose-6-Phosphate-Mediated Toxicity Determines Essentiality of OtsB2 in Mycobacterium tuberculosis In Vitro and in Mice PLoS Pathogens ·Jan Korte, Marina Alber, Carolina Trujillo, Karl Syson, Hendrik Koliwer‐Brandl, René Deenen, Karl Köhrer, Michael A. DeJesus, Travis Hartman, William R. Jacobs, Stephen Bornemann, Thomas R. Ioerger, Sabine Ehrt, Rainer Kalscheuer	2016	28
6	Mycobacterium tuberculosis Maltosyltransferase GlgE, a Genetically Validated Antituberculosis Target, Is Negatively Regulated by Ser/Thr Phosphorylation Journal of Biological Chemistry ·Jade Leiba, Karl Syson, Grégory Baronian, Isabelle Zanella‐Cléon, Rainer Kalscheuer, Laurent Kremer, Stephen Bornemann, Virginie Molle	2013	28
7	Structural Insight into How Streptomyces coelicolor Maltosyl Transferase GlgE Binds α-Maltose 1-Phosphate and Forms a Maltosyl-enzyme Intermediate Biochemistry ·Karl Syson, Clare E. M. Stevenson, Abdul Rashid, Gerhard Saalbach, Minhong Tang, Anne Tuukkanen, Dmitri I. Svergun, Stephen G. Withers, David M. Lawson, Stephen Bornemann	2014	28
8	Allosteric regulation of the partitioning of glucose-1-phosphate between glycogen and trehalose biosynthesis in Mycobacterium tuberculosis Biochimica et Biophysica Acta (BBA) - General Subjects ·Matías D. Asención Diez, Ana M. Demonte, Karl Syson, Diego G. Arias, Andrii Gorelik, Sergio A. Guerrero, Stephen Bornemann, Alberto Á. Iglesias	2014	21
9	Detection of Transglucosidase-Catalyzed Polysaccharide Synthesis on a Surface in Real Time Using Surface Plasmon Resonance Spectroscopy Journal of the American Chemical Society ·Carla Clé, A. Patrick Gunning, Karl Syson, Laura Bowater, Robert A. Field, Stephen Bornemann	2008	15
10	Ligand-bound Structures and Site-directed Mutagenesis Identify the Acceptor and Secondary Binding Sites of Streptomyces coelicolor Maltosyltransferase GlgE Journal of Biological Chemistry ·Karl Syson, Clare E. M. Stevenson, Farzana Miah, J. Elaine Barclay, Minhong Tang, Andrii Gorelik, Abdul Rashid, David M. Lawson, Stephen Bornemann	2016	10
11	Structure of the Mycobacterium smegmatis α-maltose-1-phosphate synthase GlgM Acta Crystallographica Section F Structural Biology Communications ·Karl Syson, Clare E. M. Stevenson, David M. Lawson, Stephen Bornemann	2020	4
12	A temperature-sensitive Mycobacterium smegmatis glgE mutation leads to a loss of GlgE enzyme activity and thermostability and the accumulation of α-maltose-1-phosphate Biochimica et Biophysica Acta (BBA) - General Subjects ·Karl Syson, Sibyl F. D. Batey, Steffen Schindler, Rainer Kalscheuer, Stephen Bornemann	2020	2

About Karl Syson

Karl Syson is a scholar working on Molecular Biology, Organic Chemistry, Biotechnology, Infectious Diseases and Materials Chemistry, having authored 12 papers that have together received 370 indexed citations. Recurring topics across this work include Biochemical and Molecular Research (7 papers), Carbohydrate Chemistry and Synthesis (6 papers), Enzyme Production and Characterization (5 papers), Tuberculosis Research and Epidemiology (4 papers), Enzyme Structure and Function (3 papers), Mycobacterium research and diagnosis (2 papers), Bacterial Genetics and Biotechnology (2 papers) and Microbial Metabolites in Food Biotechnology (1 paper). The work is most often cited by research in Biotechnology (130 citations), Infectious Diseases (103 citations), Organic Chemistry (106 citations), Molecular Biology (223 citations) and Nutrition and Dietetics (44 citations). Karl Syson has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include Stephen Bornemann, Rainer Kalscheuer, William R. Jacobs, Veeraraghavan Usha, Karolin Biermann, Zhen Liu, James C. Sacchettini, Gurdyal S. Besra, Brian Weinrick and Clare E. M. Stevenson. Their work appears in journals such as Journal of Biological Chemistry, PLoS Pathogens, Biochemistry, Biochimica et Biophysica Acta (BBA) - General Subjects and Nature Chemical Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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