Karel Pacák

66.5k citations

457 papers · 22.0k indexed · 6 hit papers · h-index 72

Impact in

Endocrinology, Diabetes and Metabolism top 0.02%
- Pituitary Gland Disorders and Treatments
- Hormonal Regulation and Hypertension
Behavioral Neuroscience top 0.1%
- Stress Responses and Cortisol

Papers in

Cancer Research 227
- Cancer, Hypoxia, and Metabolism 224
Endocrinology, Diabetes and Metabolism 240
- Pituitary Gland Disorders and Treatments 146
- Hormonal Regulation and Hypertension 109

Co-authors: Graeme Eisenhofer David S. Goldstein Miklós Palkovits Jacques W.M. Lenders Ιoannis Ilias Massimo Mannelli W. Marston Linehan Irwin J. Kopin
Journals: The Journal of Clinical Endocrinology & Metabolism (33 papers)Endocrine Related Cancer (24 papers)Annals of the New York Academy of Sciences (15 papers)Endocrinology (14 papers)Hormone and Metabolic Research (13 papers)
Partner nations: United States Germany Czechia

In The Last Decade

Karel Pacák

448 papers receiving 21.5k citations

Hit Papers

6 papers align trajectories log scale

Genetics, diagnosis, management and future directions of research of phaeochromocytoma and paraganglioma: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension 2020 · 211 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2020 Journal of Hypertension
2017 Proceedings of the National Academy of Sciences
2014 Cell Metabolism
2006 Circulation
2002 JAMA
2001 Endocrine Reviews

Peers

Countries citing papers authored by Karel Pacák

Since Specialization

Citations

This map shows the geographic impact of Karel Pacák's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karel Pacák with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karel Pacák more than expected).

Fields of papers citing papers by Karel Pacák

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karel Pacák. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karel Pacák. The network helps show where Karel Pacák may publish in the future.

Co-authors

The 25 scholars most cited alongside Karel Pacák, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Karel Pacák Line = papers co-authored together Karel Pacák links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Single-cell chromosome and bulk transcriptome analysis as a diagnostic tool to differentiate between localized and metastatic pheochromocytoma and sympathetic paraganglioma Oncogene ·Annika M.A. Berends, René Wardenaar, Hilda van den Bos, Andréa E. Tijhuis, Thera P. Links, Richard A. Feelders, Leo J. Hofland, Schelto Kruijff, Karel Pacák, Diana C.J. Spierings, Michiel N. Kerstens, Floris Foijer	2025	0
2	Investigation of the potential effects of estrogen receptor modulators on immune checkpoint molecules Scientific Reports ·Nikita Abramenko, F.M.D. Vellieux, Kateřina Veselá, Zdeněk Kejík, Jan Hajduch, Michal Masařík, Petr Babula, David Hoskovec, Karel Pacák, Pavel Martásek, Karel Smetana, Milan Jakubek	2024	3
3	Single agent axitinib in the management of patients with progressive pheochromocytoma and paraganglioma. Journal of Clinical Oncology ·Tito Fojo, Andrea B. Apolo, Maureen Edgerly, Karel Pacák, William D. Figg, Susan E. Bates, Jaydira Del Rivero	2024	2
4	The Immune Landscape of Pheochromocytoma and Paraganglioma: Current Advances and Perspectives Endocrine Reviews ·Ondřej Uher, Katerina Hadrava Vanova, David Taïeb, Bruna Calsina, Mercedes Robledo, Roderick Clifton‐Bligh, Karel Pacák	2024	11
5	Role of B cells in intratumoral MBTA immunotherapy of murine pheochromocytoma model Best Practice & Research Clinical Endocrinology & Metabolism ·Ondřej Uher, Katerina Hadrava Vanova, Kateřina Petrláková, Rachael N. Labitt, Radka Lencova, Andrea Frejlachova, Juan Ye, Herui Wang, Michal Masařík, Jan Ženka, Zhengping Zhuang, Karel Pacák	2024	2
6	Paediatric phaeochromocytoma and paraganglioma: A clinical update Clinical Endocrinology ·Matthew A. Nazari, Abhishek Jha, Mickey J. M. Kuo, Mayank Patel, Tamara Prodanov, Jared S. Rosenblum, Sara Talvacchio, Alberta Derkyi, Kailah Charles, Karel Pacák	2023	1
7	Early short-term effects on catecholamine levels and pituitary function in patients with pheochromocytoma or paraganglioma treated with [177Lu]Lu-DOTA-TATE therapy Frontiers in Endocrinology ·Sriram Gubbi, Mohammad Al-Jundi, Sungyoung Auh, Abhishek Jha, Joy Zou, Inna Shamis, Leah Meuter, Marianne Knue, Barış Türkbey, Liza Lindenberg, Esther Mena, Jorge A. Carrasquillo, Yating Teng, Karel Pacák, Joanna Kłubo-Gwieździńska, Jaydira Del Rivero, Frank I. Lin	2023	6
8	PD-L1 and HIF-2α Upregulation in Head and Neck Paragangliomas after Embolization Cancers ·Alessa Fischer, Umberto Macciò, Katharina Wang, Juliane Friemel, M.A. Broglie Daeppen, Diana Vetter, Kuno Lehmann, Astrid Reul, Mercedes Robledo, Constanze Hantel, Nicole Bechmann, Karel Pacák, Kathrin Zitzmann, Christoph J. Auernhammer, Ashley Grossman, Felix Beuschlein, Svenja Nölting	2023	2
9	Targeted Therapies in Pheochromocytoma and Paraganglioma The Journal of Clinical Endocrinology & Metabolism ·Katharina Wang, Joakim Crona, Felix Beuschlein, Ashley Grossman, Karel Pacák, Svenja Nölting	2022	29
10	Genetics, diagnosis, management and future directions of research of phaeochromocytoma and paraganglioma: a position statement and consensus of the Working Group on Endocrine Hypertension of the European Society of Hypertension Journal of Hypertension ·Jacques W.M. Lenders, Michiel N. Kerstens, Laurence Amar, Aleksander Prejbisz, Mercedes Robledo, David Taïeb, Karel Pacák, Joakim Crona, Tomáš Zelinka, Massimo Mannelli, Timo Deutschbein, Henri Timmers, Frédéric Castinetti, Henning Dralle, J. sen. Widimský, Anne‐Paule Gimenez‐Roqueplo, Graeme Eisenhofer Hit paper breakdown →	2020	211
11	Targeting NAD+/PARP DNA Repair Pathway as a Novel Therapeutic Approach to SDHB -Mutated Cluster I Pheochromocytoma and Paraganglioma Clinical Cancer Research ·Ying Pang, Yanxin Lu, Veronika Caisová, Yang Liu, Petra Bullova, Thanh‐Truc Huynh, Yiqiang Zhou, Di Yu, Zdeněk Fryšák, Igor Hartmann, David Taïeb, Karel Pacák, Chunzhang Yang	2018	61
12	Mapping of human brown adipose tissue in lean and obese young men Proceedings of the National Academy of Sciences ·Brooks P. Leitner, Shan Huang, Robert J. Brychta, Courtney J. Duckworth, Alison S. Baskin, Suzanne McGehee, Ṭal Ilan, William J. Dieckmann, Garima Gupta, Gerald M. Kolodny, Karel Pacák, Peter Herscovitch, Aaron M. Cypess, Kong Y. Chen Hit paper breakdown →	2017	380
13	Precision medicine in pheochromocytoma and paraganglioma: current and future concepts Journal of Internal Medicine ·Peyman Björklund, Karel Pacák, Joakim Crona	2016	31
14	Pheochromocytoma: The First Metabolic Endocrine Cancer Clinical Cancer Research ·Ivana Jochmanová, Karel Pacák	2016	45
15	Mutation-targeted therapy with sunitinib or everolimus in patients with advanced low-grade or intermediate-grade neuroendocrine tumours of the gastrointestinal tract and pancreas with or without cytoreductive surgery: protocol for a phase II clinical trial BMJ Open ·Vladimir Neychev, Seth M. Steinberg, Candice Cottle‐Delisle, Roxanne Merkel, Naris Nilubol, Jianhua Yao, Paul S. Meltzer, Karel Pacák, Stephen J. Marx, Electron Kebebew	2015	27
16	Genotype-Specific Abnormalities in Mitochondrial Function Associate with Distinct Profiles of Energy Metabolism and Catecholamine Content in Pheochromocytoma and Paraganglioma Clinical Cancer Research ·Jyotsna U. Rao, Udo F. H. Engelke, Richard J. Rodenburg, Ron A. Wevers, Karel Pacák, Graeme Eisenhofer, Nan Qin, Benno Küsters, Angelina G. Goudswaard, Jacques W.M. Lenders, Ad R. Hermus, Arjen R. Mensenkamp, Henricus P. M. Kunst, Fred C.G.J. Sweep, Henri Timmers	2013	44
17	Clinical aspects of SDHx-related pheochromocytoma and paraganglioma Endocrine Related Cancer ·Henri Timmers, Anne‐Paule Gimenez‐Roqueplo, Massimo Mannelli, Karel Pacák	2009	101
18	Cushing’s Syndrome Due to Ectopic Corticotropin Secretion: Twenty Years’ Experience at the National Institutes of Health The Journal of Clinical Endocrinology & Metabolism ·Ιoannis Ilias, David J. Torpy, Karel Pacák, Nancy Mullen, Robert Wesley, Lynnette K. Nieman	2005	477
19	Utility of Plasma Free Metanephrines for Detecting Childhood Pheochromocytoma The Journal of Clinical Endocrinology & Metabolism ·Martina Weise, Deborah P. Merke, Karel Pacák, McClellan M. Walther, Graeme Eisenhofer	2002	62
20	Decreased stress responsivity of central and peripheral catecholaminergic systems in aged 344/N Fischer rats. Journal of Clinical Investigation ·Giovanni Cizza, Karel Pacák, Richard Květňanský, Miklós Palkovits, David S. Goldstein, Linda S. Brady, Kouki Fukuhara, E. Bergamini, Irwin J. Kopin, Marc R. Blackman	1995	47

About Karel Pacák

Karel Pacák is a scholar working on Cancer Research, Endocrinology, Diabetes and Metabolism, Behavioral Neuroscience, Surgery and Neurology, having authored 457 papers that have together received 22.0k indexed citations. Recurring topics across this work include Adrenal and Paraganglionic Tumors (273 papers), Cancer, Hypoxia, and Metabolism (224 papers), Pituitary Gland Disorders and Treatments (146 papers), Hormonal Regulation and Hypertension (109 papers), Neuroblastoma Research and Treatments (47 papers), Stress Responses and Cortisol (42 papers), Glioma Diagnosis and Treatment (27 papers) and Adipose Tissue and Metabolism (25 papers). The work is most often cited by research in Endocrinology, Diabetes and Metabolism (10.2k citations), Behavioral Neuroscience (2.0k citations), Cancer Research (8.3k citations), Surgery (11.6k citations) and Neurology (2.7k citations). Karel Pacák has collaborated with scholars based in United States, Germany and Czechia. Frequent co-authors include Graeme Eisenhofer, David S. Goldstein, Miklós Palkovits, Jacques W.M. Lenders, Ιoannis Ilias, Massimo Mannelli, W. Marston Linehan, Irwin J. Kopin, McClellan M. Walther and Karen T. Adams. Their work appears in journals such as The Journal of Clinical Endocrinology & Metabolism, Endocrine Related Cancer, Annals of the New York Academy of Sciences, Endocrinology and Hormone and Metabolic Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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