Marvin H. Caruthers

13.0k total citations · 4 hit papers
168 papers, 10.7k citations indexed

About

Marvin H. Caruthers is a scholar working on Molecular Biology, Organic Chemistry and Genetics. According to data from OpenAlex, Marvin H. Caruthers has authored 168 papers receiving a total of 10.7k indexed citations (citations by other indexed papers that have themselves been cited), including 157 papers in Molecular Biology, 38 papers in Organic Chemistry and 16 papers in Genetics. Recurrent topics in Marvin H. Caruthers's work include DNA and Nucleic Acid Chemistry (115 papers), Advanced biosensing and bioanalysis techniques (51 papers) and RNA and protein synthesis mechanisms (50 papers). Marvin H. Caruthers is often cited by papers focused on DNA and Nucleic Acid Chemistry (115 papers), Advanced biosensing and bioanalysis techniques (51 papers) and RNA and protein synthesis mechanisms (50 papers). Marvin H. Caruthers collaborates with scholars based in United States, Canada and Poland. Marvin H. Caruthers's co-authors include Serge L. Beaucage, Lincoln J. McBride, Ryszard Kierzek, Eric F. Fisher, Susan M. Freier, Douglas H. Turner, Thomas Neilson, Naoki Sugimoto, J. A. Jaeger and Craig Montell and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

Marvin H. Caruthers

166 papers receiving 9.9k citations

Hit Papers

align trajectories sort by overperformance

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

1981 1.7k citations Serge L. Beaucage, Marvin H. Caruthers Tetrahedron Letters profile →
Improved free-energy parameters for predictions of RNA duplex stability.

1986 1.3k citations Marvin H. Caruthers et al. Proceedings of the National Academy of Sciences profile →
Gene Synthesis Machines: DNA Chemistry and Its Uses

1985 630 citations Marvin H. Caruthers profile →
An investigation of several deoxynucleoside phosphoramidites useful for synthesizing deoxyoligonucleotides

1983 447 citations Marvin H. Caruthers et al. Tetrahedron Letters profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Marvin H. Caruthers United States	46	9.5k	1.6k	1.5k	820	565	168	10.7k
Fritz Eckstein Germany	54	9.5k 1.0×	1.4k 0.9×	1.1k 0.7×	740 0.9×	913 1.6×	181	11.2k
Paul C. Zamecnik United States	47	8.2k 0.9×	560 0.4×	996 0.7×	447 0.5×	789 1.4×	129	10.8k
Miquel Coll Spain	48	5.8k 0.6×	753 0.5×	1.5k 1.0×	967 1.2×	489 0.9×	162	7.9k
Jesper Wengel Denmark	58	14.1k 1.5×	1.8k 1.2×	488 0.3×	1.1k 1.4×	665 1.2×	422	16.5k
L.S. Beese United States	39	6.1k 0.6×	544 0.3×	1.2k 0.8×	487 0.6×	672 1.2×	73	7.1k
Ramón Eritja Spain	53	8.9k 0.9×	1.1k 0.7×	785 0.5×	477 0.6×	334 0.6×	407	11.1k
Remy Loris Belgium	47	5.3k 0.6×	1.0k 0.7×	1.7k 1.1×	1.1k 1.4×	384 0.7×	170	7.5k
D.H. Ohlendorf United States	44	4.3k 0.5×	463 0.3×	935 0.6×	611 0.7×	892 1.6×	86	6.8k
Gregory D. Van Duyne United States	46	4.6k 0.5×	1.8k 1.1×	995 0.7×	517 0.6×	375 0.7×	95	7.2k
Gerald Zon United States	54	6.4k 0.7×	1.8k 1.1×	514 0.3×	313 0.4×	582 1.0×	207	9.3k

Countries citing papers authored by Marvin H. Caruthers

Since Specialization

Citations

This map shows the geographic impact of Marvin H. Caruthers's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marvin H. Caruthers with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marvin H. Caruthers more than expected).

Fields of papers citing papers by Marvin H. Caruthers

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marvin H. Caruthers. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marvin H. Caruthers. The network helps show where Marvin H. Caruthers may publish in the future.

Co-authorship network of co-authors of Marvin H. Caruthers

This figure shows the co-authorship network connecting the top 25 collaborators of Marvin H. Caruthers. A scholar is included among the top collaborators of Marvin H. Caruthers based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marvin H. Caruthers. Marvin H. Caruthers is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Utama, Raditya, Kuan‐Ting Lin, Christopher R. Vakoc, et al.. (2025). PKM splice-switching ASOs induce upregulation of dual-specificity phosphatases and dephosphorylation of ERK1/2 in hepatocellular carcinoma. Journal of Biological Chemistry. 301(4). 108345–108345. 2 indexed citations

Wan, Ledong, et al.. (2024). Screening Splice-Switching Antisense Oligonucleotides in Pancreas-Cancer Organoids. Nucleic Acid Therapeutics. 34(4). 188–198. 7 indexed citations

Caruthers, Marvin H., et al.. (2024). Allele-Selective Thiomorpholino Antisense Oligonucleotides as a Therapeutic Approach for Fused-in-Sarcoma Amyotrophic Lateral Sclerosis. International Journal of Molecular Sciences. 25(15). 8495–8495. 3 indexed citations

Le, Bao T., et al.. (2022). Thiomorpholino oligonucleotides as a robust class of next generation platforms for alternate mRNA splicing. Proceedings of the National Academy of Sciences. 119(36). e2207956119–e2207956119. 37 indexed citations

Kumar, Pawan & Marvin H. Caruthers. (2020). DNA Analogues Modified at the Nonlinking Positions of Phosphorus. Accounts of Chemical Research. 53(10). 2152–2166. 24 indexed citations

Jastrzębska, Katarzyna, et al.. (2020). Synthesis and Characterization of Thiophosphoramidate Morpholino Oligonucleotides and Chimeras. Journal of the American Chemical Society. 142(38). 16240–16253. 38 indexed citations

Okochi, Kenji D., Luca Monfregola, Sarah M. Dickerson, et al.. (2017). Synthesis of Small-Molecule/DNA Hybrids through On-Bead Amide-Coupling Approach. The Journal of Organic Chemistry. 82(20). 10803–10811. 8 indexed citations

Yehezkeli, Omer, et al.. (2017). Boranephosphonate DNA-Mediated Metallization of Single-Walled Carbon Nanotubes. Chemistry of Materials. 29(5). 2239–2245. 12 indexed citations

Caruthers, Marvin H.. (2014). Robert Letsinger: The father of synthetic DNA chemistry. Proceedings of the National Academy of Sciences. 111(51). 18098–18099. 3 indexed citations

10.

Caruthers, Marvin H., et al.. (2012). Alkynyl Phosphonate DNA: A Versatile “Click”able Backbone for DNA-Based Biological Applications. Journal of the American Chemical Society. 134(28). 11618–11631. 47 indexed citations

11.

Torres, Adrián Gabriel, et al.. (2011). Synthesis and biological activity of phosphonoacetate- and thiophosphonoacetate-modified 2′-O-methyl oligoribonucleotides. Organic & Biomolecular Chemistry. 10(4). 746–754. 24 indexed citations

12.

Caruthers, Marvin H., Graham Beaton, Lendell L. Cummins, et al.. (2007). Synthesis and Biochemical Studies of Dithioate DNA. Novartis Foundation symposium. 158. 158–168.

13.

Sierzchała, Agnieszka, et al.. (2003). Solid-Phase Oligodeoxynucleotide Synthesis: A Two-Step Cycle Using Peroxy Anion Deprotection. Journal of the American Chemical Society. 125(44). 13427–13441. 36 indexed citations

14.

Vaughn, James P., et al.. (1996). Inhibition of the erbB-2 Tyrosine Kinase Receptor in Breast Cancer Cells by Phosphoromonothioate and Phosphorodithioate Antisense Oligonucleotides. Nucleic Acids Research. 24(22). 4558–4564. 25 indexed citations

15.

Caruthers, Marvin H., et al.. (1996). Synthesis and preliminary biochemical studies with 5′-deoxy-5′-methylidyne phosphonate linked thymidine oligonucleotides. Tetrahedron Letters. 37(35). 6239–6242. 6 indexed citations

16.

Caruthers, Marvin H., et al.. (1991). Detection and Characterization of a Factor Which Rescues Spliceosome Assembly from a Heat-Inactivated HeLa Cell Nuclear Extract. Molecular and Cellular Biology. 11(7). 3425–3431. 8 indexed citations

17.

Eritja, Ramón, et al.. (1990). O-aryl phosphoramidites: synthesis, reactivity and evaluation of their use for solid-phase synthesis of oligonucleotides. Tetrahedron. 46(3). 721–730. 12 indexed citations

18.

Brill, Wolfgang K.‐D., John Nielsen, & Marvin H. Caruthers. (1988). Synthesis of dinucleoside phosphorodithioates via thioamidites. Tetrahedron Letters. 29(43). 5517–5520. 35 indexed citations

19.

Beaucage, Serge L. & Marvin H. Caruthers. (1981). ChemInform Abstract: DEOXYNUCLEOSIDE PHOSPHORAMIDITES. A NEW CLASS OF KEY INTERMEDIATES FOR DEOXYPOLYNUCLEOTIDE SYNTHESIS. Chemischer Informationsdienst. 12(36). 1 indexed citations

20.

Yansura, Daniel G., David V. Goeddel, & Marvin H. Caruthers. (1977). Studies on gene control regions. 2. Enzymic joining of chemically synthesized lactose operator deoxyribonucleic acid segments. Biochemistry. 16(9). 1772–1780. 25 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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