Joris Pothof

5.2k citations

36 papers · 2.3k indexed · 1 hit paper · h-index 23

Impact in

Aging top 0.5%
- Genetics, Aging, and Longevity in Model Organisms
Cancer Research top 2%
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research

Papers in ⓘ

Molecular Biology 31
- DNA Repair Mechanisms 12
- RNA Research and Splicing 8
- Circular RNAs in diseases 6
- RNA Interference and Gene Delivery 6
- RNA modifications and cancer 5
Cancer Research 18
- MicroRNA in disease regulation 11
- Carcinogens and Genotoxicity Assessment 4

Co-authors: Jan H.J. Hoeijmakers (19 shared papers)Jan Vijg (2 shared papers)Björn Schumacher (2 shared papers)Wilfred F. J. van IJcken (9 shared papers)Dik C. van Gent (7 shared papers)Erik A.C. Wiemer (7 shared papers)Wilbert P. Vermeij (3 shared papers)Marcel Tijsterman (3 shared papers)
Journals: DNA repair (2 papers)Mutation research. Fundamental and molecular mechanisms of mutagenesis (2 papers)PLoS ONE (2 papers)Clinical Cancer Research (1 paper)RNA Biology (1 paper)
Partner nations: Netherlands Germany United States

In The Last Decade

Joris Pothof

34 papers receiving 2.3k citations

Hit Papers

align trajectories log scale

The central role of DNA damage in the ageing process 2021 · 527 citations

Peers

Countries citing papers authored by Joris Pothof

Since Specialization

Citations

This map shows the geographic impact of Joris Pothof's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joris Pothof with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joris Pothof more than expected).

Fields of papers citing papers by Joris Pothof

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joris Pothof. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joris Pothof. The network helps show where Joris Pothof may publish in the future.

Co-authors

The 25 scholars most cited alongside Joris Pothof, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Joris Pothof Line = papers co-authored together Joris Pothof links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 36 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	The central role of DNA damage in the ageing process Nature ·Björn Schumacher, Joris Pothof, Jan Vijg, Jan H.J. Hoeijmakers Hit paper breakdown →	2021	527
2	MicroRNA‐mediated gene silencing modulates the UV‐induced DNA‐damage response The EMBO Journal ·Joris Pothof, Nicole S. Verkaik, Wilfred F. J. van IJcken, Erik A.C. Wiemer, Van Thanh Ta, Gijsbertus T. J. van der Horst, Nicolaas G.J. Jaspers, Dik C. van Gent, Jan H.J. Hoeijmakers, Stephan P. Persengiev	2009	194
3	miR-141 regulates KEAP1 and modulates cisplatin sensitivity in ovarian cancer cells Oncogene ·Marijn T. M. van Jaarsveld, Jozien Helleman, Antonius W.M. Boersma, Patricia F. van Kuijk, Wilfred F. J. van IJcken, Evelyn Despierre, Ignace Vergote, Ron H.J. Mathijssen, E. Berns, Jaap Verweij, Joris Pothof, Erik A.C. Wiemer	2012	180
4	Identification of genes that protect theC. elegansgenome against mutations by genome-wide RNAi Genes & Development ·Joris Pothof, Gijs van Haaften, Karen L. Thijssen, Ravi S. Kamath, Andrew Fraser, Julie Ahringer, Ronald H.A. Plasterk, Marcel Tijsterman	2003	167
5	Live-cell analysis of endogenous GFP-RPB1 uncovers rapid turnover of initiating and promoter-paused RNA Polymerase II Proceedings of the National Academy of Sciences ·Barbara Steurer, Roel C. Janssens, Bart Geverts, Marit E. Geijer, Franziska Wienholz, Arjan F. Theil, Jiang Chang, Shannon Dealy, Joris Pothof, Wiggert A. van Cappellen, Adriaan B. Houtsmuller, Jurgen A. Marteijn	2018	144
6	Has2 is required upstream of Rac1 to govern dorsal migration of lateral cells during zebrafish gastrulation Development ·Jeroen Bakkers, Carina Kramer, Joris Pothof, Nicolette E. M. Quaedvlieg, Herman P. Spaink, Matthias Hammerschmidt	2004	118
7	Genome Integrity in Aging: Human Syndromes, Mouse Models, and Therapeutic Options The Annual Review of Pharmacology and Toxicology ·Wilbert P. Vermeij, Jan H.J. Hoeijmakers, Joris Pothof	2015	86
8	MicroRNAs, the DNA damage response and cancer Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Maikel D. Wouters, Dik C. van Gent, Jan H.J. Hoeijmakers, Joris Pothof	2011	72
9	Genome-wide RNA polymerase stalling shapes the transcriptome during aging Nature Genetics ·Ákos Gyenis, Jiang Chang, Joris Demmers, Serena T. Bruens, Sander Barnhoorn, Renata M. C. Brandt, Marjolein P. Baar, Marko Rašeta, Kasper Derks, Jan H.J. Hoeijmakers, Joris Pothof	2023	71
10	Identification of Conserved Pathways of DNA-Damage Response and Radiation Protection by Genome-Wide RNAi Current Biology ·Gijs van Haaften, Ron Romeijn, Joris Pothof, Wouter Koole, Leon H.F. Mullenders, Albert Pastink, Ronald H.A. Plasterk, Marcel Tijsterman	2006	70
11	miR-634 restores drug sensitivity in resistant ovarian cancer cells by targeting the Ras-MAPK pathway Molecular Cancer ·Marijn T. M. van Jaarsveld, Patricia F. van Kuijk, Antonius W.M. Boersma, Jozien Helleman, Wilfred F. J. van IJcken, Ron H.J. Mathijssen, Joris Pothof, Els M.J.J. Berns, Jaap Verweij, Erik A.C. Wiemer	2015	69
12	Comprehensive microRNA profiling in B-cells of human centenarians by massively parallel sequencing BMC Genomics ·Saurabh Gombar, Hwa Jin Jung, Dong Feng, Brent Calder, Gil Atzmon, Nir Barzilai, Xiao‐Li Tian, Joris Pothof, Jan H.J. Hoeijmakers, Judith Campisi, Jan Vijg, Yousin Suh	2012	61
13	Developmental and Activity-Dependent miRNA Expression Profiling in Primary Hippocampal Neuron Cultures PLoS ONE ·Myrrhe van Spronsen, Eljo Y. van Battum, Marijn Kuijpers, Vamshidhar R. Vangoor, M. Liset Rietman, Joris Pothof, Laura F. Gumy, Wilfred F. J. van IJcken, Anna Akhmanova, R. Jeroen Pasterkamp, Casper C. Hoogenraad	2013	59
14	Deficiency of nucleotide excision repair is associated with mutational signature observed in cancer Genome Research ·Myrthe Jager, Francis Blokzijl, Ewart Kuijk, Johanna Bertl, Maria Vougioukalaki, Roel Janssen, Nicolle Besselink, Sander Boymans, Joep de Ligt, Jakob Skou Pedersen, Jan H.J. Hoeijmakers, Joris Pothof, Ruben van Boxtel, Edwin Cuppen	2019	57
15	Aging: not all DNA damage is equal Current Opinion in Genetics & Development ·Wilbert P. Vermeij, Jan H.J. Hoeijmakers, Joris Pothof	2014	47
16	Frequent Germline Mutations and Somatic Repeat Instability in DNA Mismatch-Repair-Deficient Caenorhabditis elegans Genetics ·Marcel Tijsterman, Joris Pothof, Ronald H.A. Plasterk	2002	43
17	Organoids Derived from Neoadjuvant FOLFIRINOX Patients Recapitulate Therapy Resistance in Pancreatic Ductal Adenocarcinoma Clinical Cancer Research ·Elham Aïda Farshadi, Jiang Chang, Bharath Sampadi, Michail Doukas, Freek Van ‘t Land, Fleur van der Sijde, Eveline E. Vietsch, Joris Pothof, Bas Groot Koerkamp, Casper H.J. van Eijck	2021	41
18	MicroRNA responses and stress granule formation modulate the DNA damage response Cell Cycle ·Joris Pothof, Nicole S. Verkaik, Jan H.J. Hoeijmakers, Dik C. van Gent	2009	41
19	DNA damage responsive microRNAs misexpressed in human cancer modulate therapy sensitivity Molecular Oncology ·Marijn T. M. van Jaarsveld, Maikel D. Wouters, Antonius W.M. Boersma, Marcel Smid, Wilfred F. J. van IJcken, Ron H.J. Mathijssen, Jan H.J. Hoeijmakers, John W.M. Martens, Steven Van Laere, Erik A.C. Wiemer, Joris Pothof	2013	35
20	Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis Cancers ·Kyra N. Smit, Jiang Chang, Kasper Derks, Jolanda Vaarwater, Tom Brands, Robert M. Verdijk, Erik A.C. Wiemer, Hanneke W. Mensink, Joris Pothof, Annelies de Klein, Emine Kılıç	2019	31

About Joris Pothof

Joris Pothof is a scholar working on Molecular Biology, Cancer Research, Physiology, Aging and Oncology, having authored 36 papers that have together received 2.3k indexed citations. Recurring topics across this work include DNA Repair Mechanisms (12 papers), MicroRNA in disease regulation (11 papers), RNA Research and Splicing (8 papers), Circular RNAs in diseases (6 papers), RNA Interference and Gene Delivery (6 papers), RNA modifications and cancer (5 papers), Genetics, Aging, and Longevity in Model Organisms (4 papers) and Carcinogens and Genotoxicity Assessment (4 papers). The work is most often cited by research in Aging (291 citations), Cancer Research (679 citations), Molecular Biology (1.7k citations), Cell Biology (184 citations) and Geriatrics and Gerontology (42 citations). Joris Pothof has collaborated with scholars based in Netherlands, Germany and United States. Frequent co-authors include Jan H.J. Hoeijmakers, Jan Vijg, Björn Schumacher, Wilfred F. J. van IJcken, Dik C. van Gent, Erik A.C. Wiemer, Wilbert P. Vermeij, Marcel Tijsterman, Ronald H.A. Plasterk and Gijs van Haaften. Their work appears in journals such as DNA repair, Mutation research. Fundamental and molecular mechanisms of mutagenesis, PLoS ONE, Clinical Cancer Research and RNA Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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