John Simms

3.5k citations

74 papers · 2.6k indexed · h-index 28

Cellular and Molecular Neuroscience top 1%
- Neuropeptides and Animal Physiology 42
Endocrinology, Diabetes and Metabolism top 2%
- Diabetes Treatment and Management 9
Health, Toxicology and Mutagenesis top 2%
Molecular Biology top 5%
- Receptor Mechanisms and Signaling 53
- Pharmacological Receptor Mechanisms and Effects 6
Civil and Structural Engineering top 5%
- Water Systems and Optimization 6
Social Psychology
- Neuroendocrine regulation and behavior 10
Oncology
- Peptidase Inhibition and Analysis 5
Radiology, Nuclear Medicine and Imaging
- Monoclonal and Polyclonal Antibodies Research 5

Co-authors: Denise Wootten Patrick M. Sexton Arthur Christopoulos David R. Poyner John R. West C.F. Forster Nicholas B. Hallam Laurence J. Miller
Cited by: Cellular and Molecular Neuroscience Endocrinology, Diabetes and Metabolism Health, Toxicology and Mutagenesis
Journals: Biochemistry (6 papers)Molecular Pharmacology (5 papers)Biochimica et Biophysica Acta (BBA) - Biomembranes (5 papers)
Partner nations: United Kingdom United States Australia

In The Last Decade

John Simms

72 papers receiving 2.6k citations

Peers

Countries citing papers authored by John Simms

Since Specialization

Citations

This map shows the geographic impact of John Simms's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Simms with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Simms more than expected).

Fields of papers citing papers by John Simms

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Simms. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Simms. The network helps show where John Simms may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John Simms, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Simms Line = papers co-authored together John Simms links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Classifying tetraspanins: A universal system for numbering residues and a proposal for naming structural motifs and subfamilies Biochimica et Biophysica Acta (BBA) - Biomembranes ·屠建伟,Alice J. Rothnie,John Simms,Roslyn M. Bill	2023	3
2	Ligand-induced conformational changes in a SMALP-encapsulated GPCR. Biochimica et Biophysica Acta (BBA) - Biomembranes ·Sarah J Routledge,Mohammed Jamshad,Pricila Kuhn,Mahlinda Mahlinda,John Simms,Alpesh Thakker,Corinne M. Spickett,Roslyn M. Bill,Timothy R. Dafforn,David R. Poyner,Mark Wheatley	2020	25
3	Interactions between RAMP2 and CRF receptors: The effect of receptor subtypes, splice variants and cell context Biochimica et Biophysica Acta (BBA) - Biomembranes ·Peter A. Selig,Matthew Harris,L.S. Keith,Ian J. Winfield,Matthew T. Harper,John Simms,Graham Ladds,Mark Wheatley,David R. Poyner	2019	14
4	Data underpinning article "Molecular dynamic simulations of CLR/RAMP1 and CLR/RAMP2 heterodimers, with and without deletions of V205 in CLR" David R. Poyner,John Simms	2018	1
5	hCALCRL mutation causes autosomal recessive nonimmune hydrops fetalis with lymphatic dysplasia The Journal of Experimental Medicine ·J N Fomulu,Fuad Al Mutairi,Reema B. Davis,Daniel O. Kechele,Allan Winterbottom,Joshua C. Snyder,Marc G. Caron,Harvey J. Kliman,Jonathan S. Berg,John Simms,David R. Poyner,Kathleen M. Caron	2018	29
6	Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex Biochemistry ·John Simms,Duan Libin,Thomas P. Sakmar,Joseph J. Gingell,Michael L. Garelja,Debbie L. Hay,Margaret A. Brimble,Paul W. R. Harris,Christopher A. Reynolds,David R. Poyner	2018	19
7	Understanding the molecular functions of the second extracellular loop (ECL2) of the calcitonin gene-related peptide (CGRP) receptor using a comprehensive mutagenesis approach Molecular and Cellular Endocrinology ·Michael J. Woolley,John Simms,Juan Carlos Mobarec,Christopher A. Reynolds,David R. Poyner,Alex C. Conner	2017	4
8	The Extracellular Surface of the GLP-1 Receptor Is a Molecular Trigger for Biased Agonism Cell ·Denise Wootten,Christopher A. Reynolds,Kevin J. Smith,Juan Carlos Mobarec,Cassandra Koole,Emilia E. Savage,Kavita Pabreja,John Simms,Hartmut Henneken,Sebastian G. B. Furness,Mengjie Liu,Philip E. Thompson,Laurence J. Miller,Arthur Christopoulos,Patrick M. Sexton	2016	119
9	Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor Molecular Cell ·Yachun Ma,Christopher S. Walker,James Barwell,Gabriel Kuteyi,John Simms,Aqfan Jamaluddin,Margaret L. Warner,Roslyn M. Bill,Paul W. R. Harris,Margaret A. Brimble,David R. Poyner,Debbie L. Hay,Augen A. Pioszak	2015	99
10	A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal Structures Molecular Pharmacology ·Denise Wootten,Christopher A. Reynolds,Cassandra Koole,Kevin J. Smith,Juan Carlos Mobarec,John Simms,Tezz Quon,Thomas Coudrat,Sebastian G. B. Furness,Laurence J. Miller,Arthur Christopoulos,Patrick M. Sexton	2015	52
11	Lifting the lid on GPCRs: the role of extracellular loops British Journal of Pharmacology ·Mark Wheatley,Denise Wootten,Mark Conner,John Simms,郭继承,유관지,David R. Poyner,James Barwell	2012	233
12	Structure–Function Studies of Muscarinic Acetylcholine Receptors Handbook of experimental pharmacology ·Katie Leach,John Simms,Patrick M. Sexton,Arthur Christopoulos	2011	20
13	Second Extracellular Loop of Human Glucagon-like Peptide-1 Receptor (GLP-1R) Has a Critical Role in GLP-1 Peptide Binding and Receptor Activation Journal of Biological Chemistry ·Cassandra Koole,Denise Wootten,John Simms,Laurence J. Miller,Arthur Christopoulos,Patrick M. Sexton	2011	77
14	Polymorphism and Ligand Dependent Changes in Human Glucagon-Like Peptide-1 Receptor (GLP-1R) Function: Allosteric Rescue of Loss of Function Mutation Molecular Pharmacology ·Cassandra Koole,Denise Wootten,John Simms,Céline Valant,Laurence J. Miller,Arthur Christopoulos,Patrick M. Sexton	2011	76
15	Evidence that Interaction between Conserved Residues in Transmembrane Helices 2, 3, and 7 Are Crucial for Human VPAC1 Receptor Activation Molecular Pharmacology ·Anton O. Chugunov,John Simms,David R. Poyner,Yves Dehouck,Marianne Rooman,Dimitri Gilis,Ingrid Langer	2010	27
16	Modulating receptor function through RAMPs: can they represent drug targets in themselves? Drug Discovery Today ·Patrick M. Sexton,David R. Poyner,John Simms,Arthur Christopoulos,Debbie L. Hay	2009	46
17	Charged Extracellular Residues, Conserved throughout a G-protein-coupled Receptor Family, Are Required for Ligand Binding, Receptor Activation, and Cell-surface Expression Journal of Biological Chemistry ·Stuart Hawtin,John Simms,Matthew T. Conner,张明金,Rosemary A. Parslow,Julie E. Trim,Jhenny Patricia,Mark Wheatley	2006	38
18	PARKS: HOW FAR IS TOO FAR? Peter Harnik,John Simms	2004	15
19	The Use and Application of Particle‐Count Data in Water Treatment Water and Environment Journal ·John Bridgeman,John Simms,S.A. Parsons	2002	2
20	Frankley Water‐Treatment Works Redevelopment: Pilot‐Scale Studies Water and Environment Journal ·Wilber Gómez,Rupert Perkins,John Simms	1991	2

About John Simms

John Simms is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology and Endocrinology, Diabetes and Metabolism, having authored 74 papers that have together received 2.6k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (53 papers), Neuropeptides and Animal Physiology (42 papers), Neuroendocrine regulation and behavior (10 papers), Diabetes Treatment and Management (9 papers), Water Systems and Optimization (6 papers), Pharmacological Receptor Mechanisms and Effects (6 papers), Peptidase Inhibition and Analysis (5 papers) and Monoclonal and Polyclonal Antibodies Research (5 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.3k citations), Endocrinology, Diabetes and Metabolism (549 citations) and Health, Toxicology and Mutagenesis (443 citations). John Simms has collaborated with scholars based in United Kingdom, United States and Australia. Frequent co-authors include Denise Wootten, Patrick M. Sexton, Arthur Christopoulos, David R. Poyner, John R. West, C.F. Forster, Nicholas B. Hallam, Laurence J. Miller, Mark Wheatley and Cassandra Koole. Their work appears in journals such as Biochemistry, Molecular Pharmacology, Biochimica et Biophysica Acta (BBA) - Biomembranes, Journal of Biological Chemistry and Biochemical Society Transactions.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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