John Sembrat

5.2k total citations · 3 hit papers
68 papers, 3.0k citations indexed

About

John Sembrat is a scholar working on Pulmonary and Respiratory Medicine, Immunology and Molecular Biology. According to data from OpenAlex, John Sembrat has authored 68 papers receiving a total of 3.0k indexed citations (citations by other indexed papers that have themselves been cited), including 46 papers in Pulmonary and Respiratory Medicine, 21 papers in Immunology and 17 papers in Molecular Biology. Recurrent topics in John Sembrat's work include Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis (22 papers), Pulmonary Hypertension Research and Treatments (15 papers) and Neonatal Respiratory Health Research (10 papers). John Sembrat is often cited by papers focused on Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis (22 papers), Pulmonary Hypertension Research and Treatments (15 papers) and Neonatal Respiratory Health Research (10 papers). John Sembrat collaborates with scholars based in United States, China and Spain. John Sembrat's co-authors include Mauricio Rojas, Ana L. Mora, Robert Lafyatis, Tracy Tabib, Eleanor Valenzi, Humberto E. Trejo Bittar, Marta Bueno, Christina Morse, Mauricio Rojas and Sruti Shiva and has published in prestigious journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Immunity.

In The Last Decade

John Sembrat

64 papers receiving 2.9k citations

Hit Papers

Proliferating SPP1/MERTK-expressing macrophages in... 2014 2026 2018 2022 2019 2014 2019 100 200 300 400
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis
    2019 461 citations Christina Morse, Tracy Tabib et al. profile →
  2. PINK1 deficiency impairs mitochondrial homeostasis and promotes lung fibrosis
    2014 447 citations Marta Bueno, Claudette M. St. Croix et al. profile →
  3. Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung disease
    2019 218 citations Eleanor Valenzi, Melissa Bulik et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
John Sembrat United States 23 1.6k 1.0k 636 421 363 68 3.0k
Harikrishna Tanjore United States 22 1.6k 1.0× 1.1k 1.0× 308 0.5× 536 1.3× 184 0.5× 27 3.2k
Vivian de Waard Netherlands 32 1.1k 0.7× 873 0.9× 820 1.3× 243 0.6× 210 0.6× 91 3.3k
Yan Y. Sanders United States 25 1.5k 1.0× 1.1k 1.1× 246 0.4× 207 0.5× 358 1.0× 35 2.7k
Shohei Shimajiri Japan 29 610 0.4× 752 0.7× 465 0.7× 254 0.6× 184 0.5× 113 2.3k
Mark Southwood United Kingdom 33 2.7k 1.6× 1.3k 1.3× 404 0.6× 274 0.7× 271 0.7× 72 4.2k
Sebastian Huss Germany 28 812 0.5× 569 0.6× 455 0.7× 808 1.9× 109 0.3× 80 2.8k
Michael E. Yeager United States 25 1.7k 1.1× 908 0.9× 221 0.3× 247 0.6× 232 0.6× 40 2.7k
Mark C. Wilkes United States 20 651 0.4× 1.2k 1.2× 292 0.5× 150 0.4× 238 0.7× 36 2.5k
Shoichi Ozaki Japan 31 679 0.4× 631 0.6× 691 1.1× 431 1.0× 298 0.8× 103 2.5k
Dick Wågsäter Sweden 31 560 0.3× 930 0.9× 949 1.5× 428 1.0× 290 0.8× 87 2.9k

Countries citing papers authored by John Sembrat

Since Specialization
Citations

This map shows the geographic impact of John Sembrat's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Sembrat with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Sembrat more than expected).

Fields of papers citing papers by John Sembrat

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Sembrat. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Sembrat. The network helps show where John Sembrat may publish in the future.

Co-authorship network of co-authors of John Sembrat

This figure shows the co-authorship network connecting the top 25 collaborators of John Sembrat. A scholar is included among the top collaborators of John Sembrat based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John Sembrat. John Sembrat is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Moghbeli, Kaveh, Marta Bueno, Andrew Craig, et al.. (2025). NKG2D blockade impairs tissue-resident memory T cell accumulation and reduces chronic lung allograft dysfunction. JCI Insight. 10(4). 1 indexed citations
2.
Dustin, Christopher M., Imad Al Ghouleh, Shuai Yuan, et al.. (2025). Redox regulation of lung endothelial PERK, unfolded protein response (UPR) and proliferation via NOX1: Targeted inhibition as a potential therapy for PAH. Redox Biology. 82. 103554–103554.
3.
Kolski‐Andreaco, Aaron, Corina Balut, John Sembrat, et al.. (2025). VX-445 (elexacaftor) inhibits chloride secretion across human bronchial epithelial cells by directly blocking KCa3.1 channels. PNAS Nexus. 4(7). pgaf211–pgaf211. 1 indexed citations
4.
Kolski‐Andreaco, Aaron, Scott Hahn, John Sembrat, et al.. (2025). (R)-vanzacaftor potentiates BKCa channels in the absence of CFTR correction or potentiation. American Journal of Physiology-Cell Physiology. 329(4). C1130–C1138.
5.
Tabib, Tracy, Mengqi Huang, Ke Yuan, et al.. (2024). Molecular Changes Implicate Angiogenesis and Arterial Remodeling in Systemic Sclerosis–Associated and Idiopathic Pulmonary Hypertension. Arteriosclerosis Thrombosis and Vascular Biology. 44(8). e210–e225. 6 indexed citations
6.
Cruz, Tamara, Nilay Mitash, John Sembrat, et al.. (2023). End-Stage Idiopathic Pulmonary Fibrosis Lung Microenvironment Promotes Impaired NK Activity. The Journal of Immunology. 211(7). 1073–1081. 8 indexed citations
7.
Bulik, Melissa, Travis Lear, Yanwen Chen, et al.. (2022). Fibronectin-EDA accumulates via reduced ubiquitination downstream of Toll-like receptor 9 activation in SSc-ILD fibroblasts. American Journal of Physiology-Lung Cellular and Molecular Physiology. 323(4). L484–L494. 5 indexed citations
8.
DeVallance, Evan, Christopher M. Dustin, Daniel Simões de Jesus, et al.. (2022). Specificity Protein 1-Mediated Promotion of CXCL12 Advances Endothelial Cell Metabolism and Proliferation in Pulmonary Hypertension. Antioxidants. 12(1). 71–71. 14 indexed citations
9.
Cillo, Anthony R., Nathanael G. Bailey, Sayali Onkar, et al.. (2022). Ewing Sarcoma and Osteosarcoma Have Distinct Immune Signatures and Intercellular Communication Networks. Clinical Cancer Research. 28(22). 4968–4982. 51 indexed citations
10.
Sahoo, Sanghamitra, Yao Li, Daniel Simões de Jesus, et al.. (2021). Notch2 suppression mimicking changes in human pulmonary hypertension modulates Notch1 and promotes endothelial cell proliferation. American Journal of Physiology-Heart and Circulatory Physiology. 321(3). H542–H557. 21 indexed citations
11.
Moghbeli, Kaveh, Eleanor Valenzi, John Sembrat, et al.. (2021). β-Agonist exposure preferentially impacts lung macrophage cyclic AMP-related gene expression in asthma and asthma COPD overlap syndrome. American Journal of Physiology-Lung Cellular and Molecular Physiology. 321(5). L837–L843. 5 indexed citations
12.
Sembrat, John, Amy Z. Stetten, Robert D. Tilton, et al.. (2021). Effect of a Surfactant Additive on Drug Transport and Distribution Uniformity After Aerosol Delivery to Ex Vivo Lungs. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 35(3). 146–153. 1 indexed citations
13.
Valenzi, Eleanor, Haopu Yang, John Sembrat, et al.. (2020). Topographic heterogeneity of lung microbiota in end-stage idiopathic pulmonary fibrosis: the Microbiome in Lung Explants-2 (MiLEs-2) study. Thorax. 76(3). 239–247. 10 indexed citations
14.
Saygın, Didem, Tracy Tabib, Humberto E. Trejo Bittar, et al.. (2020). Transcriptional profiling of lung cell populations in idiopathic pulmonary arterial hypertension. Pulmonary Circulation. 10(1). 1–15. 67 indexed citations
15.
Snyder, Mark E., John Sembrat, Kentaro Noda, et al.. (2020). Human Lung-Resident Macrophages Colocalize with and Provide Costimulation to PD1hi Tissue-Resident Memory T Cells. American Journal of Respiratory and Critical Care Medicine. 203(10). 1230–1244. 25 indexed citations
16.
Mallampalli, Rama K., Xiuying Li, Jun-Ho Jang, et al.. (2020). Cigarette smoke exposure enhances transforming acidic coiled-coil–containing protein 2 turnover and thereby promotes emphysema. JCI Insight. 5(2). 17 indexed citations
17.
Vasamsetti, Sathish Babu, Emilie Coppin, Xinyi Zhang, et al.. (2020). Apoptosis of hematopoietic progenitor-derived adipose tissue–resident macrophages contributes to insulin resistance after myocardial infarction. Science Translational Medicine. 12(553). 16 indexed citations
18.
Florentin, Jonathan, Emilie Coppin, Sathish Babu Vasamsetti, et al.. (2018). Inflammatory Macrophage Expansion in Pulmonary Hypertension Depends upon Mobilization of Blood-Borne Monocytes. The Journal of Immunology. 200(10). 3612–3625. 119 indexed citations
19.
Weathington, Nathaniel M., Diana Álvarez, John Sembrat, et al.. (2018). Ex vivo lung perfusion as a human platform for preclinical small molecule testing. JCI Insight. 3(19). 19 indexed citations
20.
Meijles, Daniel N., Sanghamitra Sahoo, Imad Al Ghouleh, et al.. (2017). The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1. Science Signaling. 10(501). 71 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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