John P. Maxwell

756 citations

23 papers · 409 indexed · h-index 8

Impact in

Hepatology top 5%
- Hepatitis C virus research
Infectious Diseases
- HIV/AIDS drug development and treatment

Papers in ⓘ

Molecular Biology 16
- Cancer-related gene regulation 10
- DNA Repair Mechanisms 3
Oncology 8
- Metal complexes synthesis and properties 3
- Peptidase Inhibition and Analysis 3

Co-authors: Kevin M. Cottrell (14 shared papers)Yu-Ping Luong (3 shared papers)Chao Lin (3 shared papers)Kai Lin (4 shared papers)Cynthia A. Gates (4 shared papers)Robert B. Perni (4 shared papers)Yunyi Wei (3 shared papers)Sue Ma (2 shared papers)
Journals: Cancer Research (5 papers)Journal of Medicinal Chemistry (3 papers)Annals of Oncology (2 papers)Molecular Cancer Therapeutics (1 paper)Clinical Cancer Research (1 paper)
Partner nations: United States United Kingdom

In The Last Decade

John P. Maxwell

21 papers receiving 384 citations

Peers

Countries citing papers authored by John P. Maxwell

Since Specialization

Citations

This map shows the geographic impact of John P. Maxwell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John P. Maxwell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John P. Maxwell more than expected).

Fields of papers citing papers by John P. Maxwell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John P. Maxwell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John P. Maxwell. The network helps show where John P. Maxwell may publish in the future.

Co-authors

The 25 scholars most cited alongside John P. Maxwell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John P. Maxwell Line = papers co-authored together John P. Maxwell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 23 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	In Vitro Resistance Studies of Hepatitis C Virus Serine Protease Inhibitors, VX-950 and BILN 2061 Journal of Biological Chemistry ·Chao Lin, Kai Lin, Yu-Ping Luong, B. Govinda Rao, Yunyi Wei, Debra Brennan, John R. Fulghum, Hsun-Mei Hsiao, Sue Ma, John P. Maxwell, Kevin M. Cottrell, Robert B. Perni, Cynthia A. Gates, Ann D. Kwong	2004	228
2	Discovery of TNG908: A Selective, Brain Penetrant, MTA-Cooperative PRMT5 Inhibitor That Is Synthetically Lethal with MTAP-Deleted Cancers Journal of Medicinal Chemistry ·Kevin M. Cottrell, Kimberly J. Briggs, Douglas A. Whittington, Haris Jahić, Janid A. Ali, Charles B. Davis, Shanzhong Gong, Deepali Gotur, Lina Gu, Patrick McCarren, Matthew R. Tonini, Alice Tsai, Erik Wilker, Hongling Yuan, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell	2024	34
3	Antimalarial sulfide, sulfone, and sulfonamide trioxanes Bioorganic & Medicinal Chemistry ·Gary H. Posner, John P. Maxwell, Hardwin O’Dowd, Mikhail Krasavin, Suji Xie, Theresa A. Shapiro	2000	31
4	Mild, Fast, and Stereoselective Epoxide Opening by Ketone Enolate Anions. Application to Synthesis of the Norlignan Curculigine The Journal of Organic Chemistry ·Gary H. Posner, John P. Maxwell, Mehmet Kahraman	2003	24
5	Inhibitors of hepatitis C virus NS3·4A protease. Effect of P4 capping groups on inhibitory potency and pharmacokinetics Bioorganic & Medicinal Chemistry Letters ·Robert B. Perni, Gurudatt Chandorkar, Kevin M. Cottrell, Cynthia A. Gates, Chao Lin, Kai Lin, Yu-Ping Luong, John P. Maxwell, Mark A. Murcko, J. PITLIK, Govinda Rao, Wayne C. Schairer, John Van Drie, Yunyi Wei	2007	16
6	Behaviour of an aziridine alkylating agent in acid solution Biochemical Pharmacology ·John P. Maxwell, Durga S. Kaushik, C G Butler	1974	11
7	New synthetic methodology for ring expansion of n-sized conjugated cycloalkenones into homoallylic n+3 lactones: 3-step synthesis of fragrant phoracantholide Tetrahedron Letters ·Gary H. Posner, Qiang Wang, Bethany Halford, Jeffrey S. Elias, John P. Maxwell	2000	11
8	Discovery of TNG462: A Highly Potent and Selective MTA-Cooperative PRMT5 Inhibitor to Target Cancers with MTAP Deletion Journal of Medicinal Chemistry ·Kevin M. Cottrell, Kimberly J. Briggs, Alice Tsai, Matthew R. Tonini, Douglas A. Whittington, Shanzhong Gong, Colin Liang, Patrick McCarren, Minjie Zhang, Wenhai Zhang, Alan Huang, John P. Maxwell	2025	7
9	TNG908 is a brain-penetrant, MTA-cooperative PRMT5 inhibitor developed for the treatment of MTAP-deleted cancers Translational Oncology ·Kimberly J. Briggs, Kevin M. Cottrell, Matthew R. Tonini, Alice Tsai, Minjie Zhang, Douglas A. Whittington, Wenhai Zhang, Steven A. Lombardo, Satoshi Yoda, Erik Wilker, Samuel R. Meier, Yi Yu, Teng Teng, Alan Huang, John P. Maxwell	2025	6
10	Abstract 3941: TNG908 is an MTAPnull-selective PRMT5 inhibitor that drives tumor regressions in MTAP-deleted xenograft models across multiple histologies Cancer Research ·Kimberly J. Briggs, Kevin M. Cottrell, Matthew R. Tonini, Erik Wilker, Lina Gu, Charles B. Davis, Minjie Zhang, Doug Whittington, Deepali Gotur, Matthew J. Goldstein, Heather DiBenedetto, Marc S. Rudoltz, Alan Huang, John P. Maxwell	2022	5
11	Abstract P5-06-05: Preclinical characterization of VX-984, a selective DNA-dependent protein kinase (DNA-PK) inhibitor in combination with doxorubicin in breast and ovarian cancers Cancer Research ·D. Boucher, David Newsome, Daigo Takemoto, Shawn Hillier, Y Wang, Reiko Arimoto, John P. Maxwell, Paul S. Charifson, SZ Fields, Kirk Tanner, MS Penney	2017	5
12	Abstract 3716: Potent radiation enhancement with VX-984, a selective DNA-PKcs inhibitor for the treatment of NSCLC Cancer Research ·Diane M. Boucher, Russell R. Hoover, Yuxin Wang, Yong Gu, David Newsome, Pamella J. Ford, Cameron Stuver Moody, Véronique Damagnez, Reiko Arimoto, Shawn Hillier, Mark Wood, William Markland, Brenda K. Eustace, Kevin M. Cottrell, Marina S. Penney, Brinley F. Furey, Kirk Tanner, John P. Maxwell, Paul S. Charifson	2016	5
13	Abstract B054: TNG348, a selective USP1 inhibitor, shows strong preclinical combination activity with PARP inhibitors and other agents targeting DNA repair Molecular Cancer Therapeutics ·Antoine Simoneau, Charlotte Pratt, Grace Comer, Hsin‐Jung Wu, Ashley H. Choi, Tenzing Khendu, Samuel R. Meier, Yi Yu, Shangtao Liu, Wenhai Zhang, Douglas A. Whittington, William D. Mallender, Sirimas Sudsakorn, Yingnan Chen, Brian B. Haines, Scott Throner, Adam Crystal, Alan Huang, John P. Maxwell, Jannik N. Andersen	2023	5
14	Preclinical characterization of the selective DNA-dependent protein kinase (DNA-PK) inhibitor VX-984 in combination with chemotherapy Annals of Oncology ·D. Boucher, Shawn Hillier, David Newsome, Y. Wang, Daigo Takemoto, Yong Gu, William Markland, Russell R. Hoover, Reiko Arimoto, John P. Maxwell, Scott Z. Fields, Paul S. Charifson, Marina S. Penney, Kirk Tanner	2016	4
15	EXTH-63. MTA-COOPERATIVE PRMT5 INHIBITORS ARE EFFICACIOUS IN MTAP-DELETED MALIGNANT PERIPHERAL NERVE SHEATH TUMOR MODELS Neuro-Oncology ·Dana C. Borcherding, Xiaochun Zhang, Minjie Zhang, Himanshi Bhatia, Yang Lyu, Kevin He, Liuzhan Yang, Kuangying Yang, Heather DiBenedetto, Alice Tsai, Alan Huang, John P. Maxwell, Kevin M. Cottrell, Kimberly J. Briggs, Angela C. Hirbe	2023	3
16	24P Evidence for synergy between TNG908, an MTAPnull-selective PRMT5 inhibitor, and sotorasib in an MTAPnull/KRASG12C xenograft model Annals of Oncology ·Karen K. Briggs, G. Corriea, Alice Tsai, M. Zhang, Matthew R. Tonini, Erik Wilker, Charles B. Davis, Kevin M. Cottrell, John P. Maxwell, Alan Huang	2022	3
17	MTA-Cooperative PRMT5 Inhibitors: Mechanism Switching Through Structure-Based Design Journal of Medicinal Chemistry ·Kevin M. Cottrell, Douglas A. Whittington, Kimberly J. Briggs, Haris Jahić, Janid A. Ali, Alvaro J. Amor, Deepali Gotur, Matthew R. Tonini, Wenhai Zhang, Alan Huang, John P. Maxwell	2025	3
18	Abstract 3452: TNG908, a brain-penetrant MTA-cooperative PRMT5 inhibitor, is efficacious in preclinical glioblastoma models Cancer Research ·Minjie Zhang, Alice Tsai, Kevin M. Cottrell, Brian B. Haines, Erik Wilker, Heather DiBenedetto, R. A. Weitzman, Alan Huang, Charles B. Davis, John P. Maxwell, Kimberly J. Briggs	2023	3
19	Inhibitors of Hepatitis C Virus NS3.4A Protease: P2 Proline Variants Letters in Drug Design & Discovery ·Luc J. Farmer, Shawn Britt, Kevin M. Cottrell, John J. Court, Lawrence F. Courtney, David D. Deininger, Cynthia A. Gates, Scott L. Harbeson, Kai Lin, Chao Lin, Yu Ping C. Luong, John P. Maxwell, J. PITLIK, D. N. Rao, Wayne C. Schairer, John A. Thomson, Roger D. Tung, John Van Drie, Yunyi Wei, Robert B. Perni	2005	3
20	Abstract 4527: TNG348 is synergistic with PARP inhibitors in tumor models with elevated replication stress Cancer Research ·Antoine Simoneau, Hsin‐Jung Wu, Charlotte Pratt, Grace Comer, Shangtao Liu, Samuel R. Meier, Tenzing Khendu, Ashley H. Choi, Hongxiang Zhang, Binzhang Shen, Douglas A. Whittington, Sirimas Sudsakorn, Wenhai Zhang, Yi Yu, Yingnan Chen, Brian B. Haines, Adam Crystal, Jannik N. Andersen, John P. Maxwell, Scott Throner	2024	1

About John P. Maxwell

John P. Maxwell is a scholar working on Molecular Biology, Oncology, Organic Chemistry, Hepatology and Infectious Diseases, having authored 23 papers that have together received 409 indexed citations. Recurring topics across this work include Cancer-related gene regulation (10 papers), Synthesis and Catalytic Reactions (4 papers), Hepatitis C virus research (4 papers), DNA Repair Mechanisms (3 papers), HIV/AIDS drug development and treatment (3 papers), Metal complexes synthesis and properties (3 papers), Peptidase Inhibition and Analysis (3 papers) and Synthetic Organic Chemistry Methods (2 papers). The work is most often cited by research in Hepatology (212 citations), Infectious Diseases (107 citations), Epidemiology (154 citations), Virology (18 citations) and Organic Chemistry (79 citations). John P. Maxwell has collaborated with scholars based in United States and United Kingdom. Frequent co-authors include Kevin M. Cottrell, Yu-Ping Luong, Chao Lin, Kai Lin, Cynthia A. Gates, Robert B. Perni, Yunyi Wei, Sue Ma, Ann D. Kwong and John R. Fulghum. Their work appears in journals such as Cancer Research, Journal of Medicinal Chemistry, Annals of Oncology, Molecular Cancer Therapeutics and Clinical Cancer Research.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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