John C. Castle

13.9k total citations · 3 hit papers
55 papers, 9.3k citations indexed

About

John C. Castle is a scholar working on Molecular Biology, Cancer Research and Geophysics. According to data from OpenAlex, John C. Castle has authored 55 papers receiving a total of 9.3k indexed citations (citations by other indexed papers that have themselves been cited), including 33 papers in Molecular Biology, 12 papers in Cancer Research and 8 papers in Geophysics. Recurrent topics in John C. Castle's work include RNA modifications and cancer (12 papers), RNA Research and Splicing (11 papers) and Geological and Geochemical Analysis (8 papers). John C. Castle is often cited by papers focused on RNA modifications and cancer (12 papers), RNA Research and Splicing (11 papers) and Geological and Geochemical Analysis (8 papers). John C. Castle collaborates with scholars based in United States, Germany and United Kingdom. John C. Castle's co-authors include Jason M. Johnson, Philip W. Garrett-Engele, Peter S. Linsley, Andrew Grimson, Janell M. Schelter, Lee P. Lim, David P. Bartel, Nelson C. Lau, Christopher D. Armour and Zhengyan Kan and has published in prestigious journals such as Nature, Science and Proceedings of the National Academy of Sciences.

In The Last Decade

John C. Castle

54 papers receiving 9.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

2005 3.9k citations Philip W. Garrett-Engele, John C. Castle et al. profile →
Genome-Wide Survey of Human Alternative Pre-mRNA Splicing with Exon Junction Microarrays

2003 1.1k citations Jason M. Johnson, John C. Castle et al. profile →
Exploiting the Mutanome for Tumor Vaccination

2012 617 citations John C. Castle, Sebastian Kreiter et al. Cancer Research profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
John C. Castle United States	33	7.2k	3.8k	1.1k	902	843	55	9.3k
Stephen E. Moss United Kingdom	43	6.9k 1.0×	1.4k 0.4×	1.6k 1.4×	736 0.8×	313 0.4×	118	9.3k
Jeffrey Ross United States	52	6.5k 0.9×	695 0.2×	688 0.6×	581 0.6×	878 1.0×	86	8.6k
Takashi Nagano Japan	37	5.6k 0.8×	2.4k 0.7×	243 0.2×	174 0.2×	953 1.1×	81	7.1k
Rainer de Martin Austria	43	3.6k 0.5×	1.8k 0.5×	2.3k 2.0×	1.1k 1.2×	425 0.5×	139	7.3k
Nicholas K. Hayward Australia	70	9.4k 1.3×	3.1k 0.8×	1.9k 1.7×	6.5k 7.3×	2.2k 2.6×	331	16.5k
Joel R. Neilson United States	36	7.0k 1.0×	3.4k 0.9×	1.0k 0.9×	566 0.6×	757 0.9×	78	9.4k
Mark T. Bedford United States	77	17.8k 2.5×	928 0.2×	765 0.7×	1.6k 1.8×	1.6k 1.9×	208	19.9k
Alistair R. R. Forrest Australia	45	6.0k 0.8×	2.3k 0.6×	1.2k 1.1×	620 0.7×	698 0.8×	125	7.8k
Björn Schwanhäußer Germany	8	7.5k 1.0×	2.9k 0.8×	717 0.6×	446 0.5×	536 0.6×	8	9.4k

Countries citing papers authored by John C. Castle

Since Specialization

Citations

This map shows the geographic impact of John C. Castle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John C. Castle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John C. Castle more than expected).

Fields of papers citing papers by John C. Castle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John C. Castle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John C. Castle. The network helps show where John C. Castle may publish in the future.

Co-authorship network of co-authors of John C. Castle

This figure shows the co-authorship network connecting the top 25 collaborators of John C. Castle. A scholar is included among the top collaborators of John C. Castle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John C. Castle. John C. Castle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Castle, John C., et al.. (2023). An evaluation of clinical fellow programmes in an acute teaching hospital trust. British Journal of Hospital Medicine. 84(10). 1–6. 1 indexed citations

Monterisi, Stefania, Miguel J. Lobo, John C. Castle, et al.. (2017). PDE2A2 regulates mitochondria morphology and apoptotic cell death via local modulation of cAMP/PKA signalling. eLife. 6. 78 indexed citations

Castle, John C., Martin Löewer, Sebastian Boegel, et al.. (2014). Mutated tumor alleles are expressed according to their DNA frequency. Scientific Reports. 4(1). 4743–4743. 33 indexed citations

Castle, John C., Sebastian Kreiter, Jan Diekmann, et al.. (2012). Exploiting the Mutanome for Tumor Vaccination. Cancer Research. 72(5). 1081–1091. 617 indexed citations breakdown →

Krupp, M, Jens U. Marquardt, Uğur Şahin, et al.. (2012). RNA-Seq Atlas—a reference database for gene expression profiling in normal tissue by next-generation sequencing. Bioinformatics. 28(8). 1184–1185. 122 indexed citations

Vignali, Marissa, Christopher D. Armour, Jingyang Chen, et al.. (2011). NSR-seq transcriptional profiling enables identification of a gene signature of Plasmodium falciparum parasites infecting children. Journal of Clinical Investigation. 121(3). 1119–1129. 56 indexed citations

Hirakawa, Hidetada, Yasuhiro Oda, Christopher D. Armour, et al.. (2011). Activity of the Rhodopseudomonas palustris p-Coumaroyl-Homoserine Lactone-Responsive Transcription Factor RpaR. Journal of Bacteriology. 193(10). 2598–2607. 35 indexed citations

Peng, Xinxia, Lisa E. Gralinski, Christopher D. Armour, et al.. (2010). Unique Signatures of Long Noncoding RNA Expression in Response to Virus Infection and Altered Innate Immune Signaling. mBio. 1(5). 214 indexed citations

Armour, Christopher D., John C. Castle, Ronghua Chen, et al.. (2009). Digital transcriptome profiling using selective hexamer priming for cDNA synthesis. Nature Methods. 6(9). 647–649. 125 indexed citations

10.

Castle, John C., Yoshikazu Hara, Christopher K. Raymond, et al.. (2009). ACC2 Is Expressed at High Levels Human White Adipose and Has an Isoform with a Novel N-Terminus. PLoS ONE. 4(2). e4369–e4369. 31 indexed citations

11.

She, Xinwei, Carol A. Rohl, John C. Castle, et al.. (2009). Definition, conservation and epigenetics of housekeeping and tissue-enriched genes. BMC Genomics. 10(1). 269–269. 120 indexed citations

12.

Zhang, Chaolin, Zuo‐Feng Zhang, John C. Castle, et al.. (2008). Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2 (Genes and Development (2008) 22 (2550-2563)). Genes & Development. 22(20). 46 indexed citations

13.

Zhang, Chaolin, Zuo‐Feng Zhang, John C. Castle, et al.. (2008). Defining the regulatory network of the tissue-specific splicing factors Fox-1 and Fox-2. Genes & Development. 22(18). 2550–2563. 241 indexed citations

14.

Cheung, York-Fong, Zhengyan Kan, Philip W. Garrett-Engele, et al.. (2007). PDE4B5, a Novel, Super-Short, Brain-Specific cAMP Phosphodiesterase-4 Variant Whose Isoform-Specifying N-Terminal Region Is Identical to That of cAMP Phosphodiesterase-4D6 (PDE4D6). Journal of Pharmacology and Experimental Therapeutics. 322(2). 600–609. 52 indexed citations

15.

Bleasby, Kelly, John C. Castle, C. J. Roberts, et al.. (2006). Expression profiles of 50 xenobiotic transporter genes in humans and pre-clinical species: A resource for investigations into drug disposition. Xenobiotica. 36(10-11). 963–988. 216 indexed citations

16.

Young, Juan I., John C. Castle, Juan Crespo-Barreto, et al.. (2005). Regulation of RNA splicing by the methylation-dependent transcriptional repressor methyl-CpG binding protein 2. Proceedings of the National Academy of Sciences. 102(49). 17551–17558. 368 indexed citations

17.

Radich, Jerald P., Mao Mao, S. Stepaniants, et al.. (2004). Individual-specific variation of gene expression in peripheral blood leukocytes. Genomics. 83(6). 980–988. 106 indexed citations

18.

Castle, John C., Christopher D. Armour, Sven Duenwald, et al.. (2003). Optimization of oligonucleotide arrays and RNA amplification protocols for analysis of transcript structure and alternative splicing. Genome biology. 4(10). R66–R66. 70 indexed citations

19.

Castle, John C. & R. D. van der Hilst. (2003). Searching for seismic scattering off mantle interfaces between 800 km and 2000 km depth. Journal of Geophysical Research Atmospheres. 108(B2). 41 indexed citations

20.

Castle, John C., et al.. (2000). Shear wave speeds at the base of the mantle. Journal of Geophysical Research Atmospheres. 105(B9). 21543–21557. 36 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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