John Ayrton

1.8k citations

35 papers · 1.5k indexed · h-index 23

Impact in

Molecular Medicine top 2%
- Antibiotic Resistance in Bacteria
Spectroscopy top 2%
- Analytical Chemistry and Chromatography
- Mass Spectrometry Techniques and Applications

Papers in

Molecular Medicine 5
- Antibiotic Resistance in Bacteria 5
Spectroscopy 12
- Analytical Chemistry and Chromatography 12
- Mass Spectrometry Techniques and Applications 7

Co-authors: Robert S. Plumb Gordon J. Dear David N. Mallett Stuart M. Harding William J. Leavens P.E. Williams Malcolm Rowland Yanling He
Journals: Rapid Communications in Mass Spectrometry (9 papers)Xenobiotica (5 papers)Journal of Antimicrobial Chemotherapy (4 papers)Pharmaceutical Research (3 papers)Antimicrobial Agents and Chemotherapy (2 papers)
Partner nations: United Kingdom United States Netherlands

In The Last Decade

John Ayrton

35 papers receiving 1.3k citations

Peers

Countries citing papers authored by John Ayrton

Since Specialization

Citations

This map shows the geographic impact of John Ayrton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John Ayrton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John Ayrton more than expected).

Fields of papers citing papers by John Ayrton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John Ayrton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John Ayrton. The network helps show where John Ayrton may publish in the future.

Co-authors

The 25 scholars most cited alongside John Ayrton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John Ayrton Line = papers co-authored together John Ayrton links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	In vitro and clinical data demonstrate negligible risk of drug–drug interactions with opelconazole, a novel inhaled antifungal agent Journal of Antimicrobial Chemotherapy ·Lindsey Cass, John Ayrton, Roger J. M. Brüggemann, Jerome A. Moore, Ubaldo J. Martin, Michael Domsgen, Lasser Theo, Lance Berman	2025	2
2	First-in-Human Phase I Dose Escalation Study of a Second-Generation Non-Ansamycin HSP90 Inhibitor, AT13387, in Patients with Advanced Solid Tumors Clinical Cancer Research ·Geoffrey I. Shapiro, Eunice L. Kwak, Bruce J. Dezube, Murray Yule, John Ayrton, John F. Lyons, Daruka Mahadevan	2014	75
3	A Phase I and Pharmacodynamic Study of AT9283, a Small-Molecule Inhibitor of Aurora Kinases in Patients With Relapsed/Refractory Leukemia or Myelofibrosis Clinical Lymphoma Myeloma & Leukemia ·James M. Foran, Farhad Ravandi, William G. Wierda, Guillermo Garcia‐Manero, Srđan Verstovšek, Tapan M. Kadia, Jan A. Burger, Murray Yule, Gillian Langford, John F. Lyons, John Ayrton, Victoria Lock, G. Borthakur, Jörge E. Cortes, Hagop M. Kantarjian	2013	37
4	Direct analysis of pharmaceutical compounds in human plasma with chromatographic resolution using an alkyl‐bonded silica rod column Rapid Communications in Mass Spectrometry ·Robert S. Plumb, Gordon J. Dear, David N. Mallett, John Ayrton	2001	52
5	Mass directed peak selection, an efficient method of drug metabolite identification using directly coupled liquid chromatography–mass spectrometry–nuclear magnetic resonance spectroscopy Journal of Chromatography B Biomedical Sciences and Applications ·Gordon J. Dear, Robert S. Plumb, Brian C. Sweatman, John Ayrton, John C. Lindon, Jeremy K. Nicholson, D. K. Chesheva	2000	22
6	Ultra-high flow rate capillary liquid chromatography with mass spectrometric detection for the direct analysis of pharmaceuticals in plasma at sub-nanogram per millilitre concentrations Rapid Communications in Mass Spectrometry ·John Ayrton, R. A. Clare, Gordon J. Dear, David N. Mallett, Robert S. Plumb	1999	34
7	Tandem mass spectrometry linked fraction collection for the isolation of drug metabolites from biological matrices Rapid Communications in Mass Spectrometry ·Gordon J. Dear, Robert S. Plumb, Brian C. Sweatman, D. K. Chesheva, John Ayrton	1999	12
8	The use of preparative high performance liquid chromatography with tandem mass spectrometric directed fraction collection for the isolation and characterisation of drug metabolites in urine by nuclear magnetic resonance spectroscopy and liquid chromatography/sequential mass spectrometry Rapid Communications in Mass Spectrometry ·Robert S. Plumb, John Ayrton, Gordon J. Dear, Brian C. Sweatman, D. K. Chesheva	1999	19
9	The application of fast gradient capillary liquid chromatography/mass spectrometry to the analysis of pharmaceuticals in biofluids Rapid Communications in Mass Spectrometry ·Robert S. Plumb, Gordon J. Dear, David N. Mallett, Mary T.. Parisi, John Ayrton, E. E. Kobi	1999	11
10	The rapid identification of drug metabolites using capillary liquid chromatography coupled to an ion trap mass spectrometer Rapid Communications in Mass Spectrometry ·Gordon J. Dear, John Ayrton, Robert S. Plumb, Mary T.. Parisi	1999	39
11	Optimisation and routine use of generic ultra-high flow-rate liquid chromatography with mass spectrometric detection for the direct on-line analysis of pharmaceuticals in plasma Journal of Chromatography A ·John Ayrton, Gordon J. Dear, William J. Leavens, David N. Mallett, Robert S. Plumb	1998	64
12	Species Differences in Size Discrimination in the Paracellular Pathway Reflected by Oral Bioavailability of Poly(ethylene glycol) and d-Peptides Journal of Pharmaceutical Sciences ·Yanling He, Mona S. Gouida, Geoffrey Warhurst, Larry Gifford, David W. Walker, John Ayrton, R. Eastmond, Malcolm Rowland	1998	124
13	Application of a generic fast gradient liquid chromatography tandem mass spectrometry method for the analysis of cytochrome P450 probe substrates Rapid Communications in Mass Spectrometry ·John Ayrton, Robert S. Plumb, William J. Leavens, David N. Mallett, Maurice Dickins, Gordon J. Dear	1998	88
14	Influence of Morphometric Factors on Quantitation of Paracellular Permeability of Intestinal Epithelia In Vitro Pharmaceutical Research ·Andrew Collett, David W. Walker, Erika Sims, Yanling He, Peter Speers, John Ayrton, Malcolm Rowland, Geoffrey Warhurst	1997	30
15	Expression of human cytochrome P4501A1 (CYP1A1) in Saccharomyces cerevisiae inhibits cell division Xenobiotica ·Alan Beresford, Rodney J. Taylor, سمانه قربی چلکی, John Ayrton, Geoffrey T. Tucker, S. W. Ellis	1996	1
16	Porous graphitic carbon shows promise for the rapid chromatographic analysis of polar drug metabolites Journal of Chromatography B Biomedical Sciences and Applications ·John Ayrton, M. Blair Evans, Atef Abo Talib, Robert S. Plumb	1995	19
17	Lacidipine metabolism in rat and dog: identification and synthesis of main metabolites Xenobiotica ·晋也川野, Mario Pellegatti, John H. Blume, John Ayrton, محيي الدين أتامان, John Maltas	1992	5
18	Absorption, distribution and excretion of lacidipine, a dihydropyridine calcium antagonist, in rat and dog Xenobiotica ·Mario Pellegatti, 晋也川野, John Ayrton, Glenda L. Evans, A.J. Harker	1990	18
19	The comparative pharmacokinetics of ceftazidime and cefotaxime in healthy volunteers Journal of Antimicrobial Chemotherapy ·Stuart M. Harding, Robert Lengelé, Joseph Thornton, John Ayrton, Melanie Hogg	1981	81
20	Assay of ceftazidime in biological fluids using high-pressure liquid chromatography Journal of Antimicrobial Chemotherapy ·John Ayrton	1981	70

About John Ayrton

John Ayrton is a scholar working on Molecular Medicine, Spectroscopy, Pharmacology, Pharmacology and Pharmaceutical Science, having authored 35 papers that have together received 1.5k indexed citations. Recurring topics across this work include Analytical Chemistry and Chromatography (12 papers), Mass Spectrometry Techniques and Applications (7 papers), Metabolomics and Mass Spectrometry Studies (6 papers), Antibiotics Pharmacokinetics and Efficacy (6 papers), Microfluidic and Capillary Electrophoresis Applications (6 papers), Drug Transport and Resistance Mechanisms (5 papers), Antibiotic Resistance in Bacteria (5 papers) and Antifungal resistance and susceptibility (4 papers). The work is most often cited by research in Molecular Medicine (194 citations), Spectroscopy (535 citations), Pharmacology (340 citations), Pharmaceutical Science (119 citations) and Pharmacology (149 citations). John Ayrton has collaborated with scholars based in United Kingdom, United States and Netherlands. Frequent co-authors include Robert S. Plumb, Gordon J. Dear, David N. Mallett, Stuart M. Harding, William J. Leavens, P.E. Williams, Malcolm Rowland, Yanling He, Geoffrey Warhurst and David W. Walker. Their work appears in journals such as Rapid Communications in Mass Spectrometry, Xenobiotica, Journal of Antimicrobial Chemotherapy, Pharmaceutical Research and Antimicrobial Agents and Chemotherapy.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact