John A. Hadfield

3.6k citations

63 papers · 3.0k indexed · 2 hit papers · h-index 22

Impact in

Toxicology top 1%
- Bioactive Compounds and Antitumor Agents
Organic Chemistry top 1%
- Synthesis and biological activity
- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Multicomponent Synthesis of Heterocycles

Papers in

Toxicology 6
- Bioactive Compounds and Antitumor Agents 6
Organic Chemistry 30
- Synthesis and biological activity 15
- Click Chemistry and Applications 10
- Oxidative Organic Chemistry Reactions 8

Co-authors: Alan T. McGown Nicholas J. Lawrence Donald M. Watkin Allan M. Jordan Sylvie Ducki David Rennison Keira Gaukroger D F L Watkin
Journals: Bioorganic & Medicinal Chemistry Letters (5 papers)The Lancet (5 papers)British Journal of Cancer (3 papers)Planta Medica (3 papers)Journal of the Chemical Society Perkin Transactions 1 (3 papers)
Partner nations: United Kingdom Netherlands Italy

In The Last Decade

John A. Hadfield

62 papers receiving 2.9k citations

Hit Papers

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Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle 1998 · 570 citations

Peers

Countries citing papers authored by John A. Hadfield

Since Specialization

Citations

This map shows the geographic impact of John A. Hadfield's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John A. Hadfield with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John A. Hadfield more than expected).

Fields of papers citing papers by John A. Hadfield

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John A. Hadfield. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John A. Hadfield. The network helps show where John A. Hadfield may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John A. Hadfield, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John A. Hadfield Line = papers co-authored together John A. Hadfield links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Spectroscopy and fluorescence lifetime imaging in live cells of a cyano-substituted combretastatin University of Salford Institutional Repository (University of Salford) ·فؤاد غربالي, Roger H. Bisby, Stanley W. Botchway, Joseph FARHI, John A. Hadfield, Anthony W. Parker, Michael Towrie	2014	7
2	Novel cyanocombretastatins as potent tubulin polymerisation inhibitors Bioorganic & Medicinal Chemistry Letters ·E. Tilemans, John A. Hadfield, G. WINTERS, SIMON MPHUKA	2012	13
3	Fluorescence lifetime imaging of E-combretastatin uptake and distribution in live mammalian cells European Journal of Cancer ·Roger H. Bisby, Stanley W. Botchway, John A. Hadfield, Alan T. McGown, Anthony W. Parker, فؤاد غربالي	2011	20
4	An efficient synthesis of paracetamol glucuronide from paracetamol Journal of Chemical Research Synopses ·Richard T. Brown, Andreas Höftmann, Alan T. McGown, John A. Hadfield	2010	1
5	Tubulin-binding dibenz[c,e]oxepines as colchinol analogues for targeting tumour vasculature Organic & Biomolecular Chemistry ·David J. Edwards, John A. Hadfield, Timothy W. Wallace, Sylvie Ducki	2010	16
6	Analogues of Y27632 increase gap junction communication and suppress the formation of transformed NIH3T3 colonies British Journal of Cancer ·Lynne Hampson, Xiaotong He, Antony W. Oliver, John A. Hadfield, Qiao Wen-jing, J. A. V. Butler, Andrew McGown, Henry C Kitchener, Ian Hampson	2009	10
7	Synthesis and evaluation of double bond substituted combretastatins European Journal of Medicinal Chemistry ·John A. Hadfield, Keira Gaukroger, G. WINTERS, Margarita Stepanovna Vykhrystyuk, Nicholas J. Lawrence, Alan T. McGown	2005	29
8	Functional comparison of annexin V analogues labeled indirectly and directly with iodine-124 Nuclear Medicine and Biology ·P. Notario-Fernández, S. Komonjida, David Shaw, Rodrigo de Castro Cardoso, D. L. Hastings, John A. Hadfield, Andrew J. Reader, D Allan, P. J. Julyan, Alastair J.M. Watson, Jamal Zweit	2005	30
9	The total synthesis of an aurone isolated from Uvaria hamiltonii: aurones and flavones as anticancer agents Bioorganic & Medicinal Chemistry Letters ·Nicholas J. Lawrence, David Rennison, Alan T. McGown, John A. Hadfield	2003	112
10	Cytotoxic michael-type amine adducts of α-methylene lactones alantolactone and isoalantolactone Bioorganic & Medicinal Chemistry Letters ·Nicholas J. Lawrence, Alan T. McGown, فريدة بولسنان, John A. Hadfield, Robin G. Pritchard	2001	82
11	Isoflavones inhibit intestinal epithelial cell proliferation and induce apoptosis in vitro British Journal of Cancer ·Catherine Booth, Emil von Schönaich-Carolath, John A. Hadfield, AT McGown, C.S. Potten	1999	79
12	Potent antimitotic and cell growth inhibitory properties of substituted chalcones Bioorganic & Medicinal Chemistry Letters ·Sylvie Ducki, 秀樹奥, John A. Hadfield, Indri Septi Guntari, Nicholas J. Lawrence, Alan T. McGown, David Rennison	1998	323
13	Tubulin as a target for anticancer drugs: Agents which interact with the mitotic spindle Medicinal Research Reviews ·Allan M. Jordan, John A. Hadfield, Nicholas J. Lawrence, Alan T. McGown Hit paper breakdown →	1998	570
14	Isolation ofE-1-(4′-Hydroxyphenyl)-but-1-en-2-one fromScutellaria barbata Planta Medica ·Sylvie Ducki, John A. Hadfield, Nicholas J. Lawrence, Cirrincione Giansalvo, Alan T. McGown, Xiuguo Zhang	1996	40
15	Molecular modeling of the interaction of anthracenyl-amino acid topoisomerase inhibitors with the DNA sequence d(CGTACG) Anti-Cancer Drugs ·Jeffrey L. Cummings, John A. Hadfield, C. Papaparaskeva, Alan T. McGown, John F. Smyth	1996	4
16	Isolation of Aurantiamide Acetate fromArisaema erubescens Planta Medica ·Sylvie Ducki, John A. Hadfield, Xiuguo Zhang, Nicholas J. Lawrence, Alan T. McGown	1996	15
17	Isolation of Paeonol fromArisaema erubescens Planta Medica ·Sylvie Ducki, John A. Hadfield, Nicholas J. Lawrence, Xiuguo Zhang, Alan T. McGown	1995	28
18	Biochemistry of topoisomerase I and II inhibition by anthracenyl-amino acid conjugates Biochemical Pharmacology ·C. Papaparaskeva, Jeffrey L. Cummings, Janet S. Macpherson, John A. Hadfield, John F. Smyth	1995	18
19	Synthesis of 2,6-dimethyl-1,4,4a,5,8,8a,9a,10a-octahydro-9,10-anthraquinone and its 2,7-dimethyl isomer. Journal of Chemical Research Synopses ·Richard T. Brown, Brian W. Fox, John A. Hadfield, Sh. Nasiri	1994	0
20	Postoperative Wound Infection The Lancet ·John A. Hadfield, Donald M. Watkin Hit paper breakdown →	1965	344

About John A. Hadfield

John A. Hadfield is a scholar working on Toxicology, Organic Chemistry, Pharmacology, Biophysics and Applied Microbiology and Biotechnology, having authored 63 papers that have together received 3.0k indexed citations. Recurring topics across this work include Synthesis and biological activity (15 papers), Click Chemistry and Applications (10 papers), Oxidative Organic Chemistry Reactions (8 papers), Cancer therapeutics and mechanisms (7 papers), Synthesis of Organic Compounds (7 papers), Bioactive Compounds and Antitumor Agents (6 papers), Chemical Synthesis and Analysis (5 papers) and Microtubule and mitosis dynamics (4 papers). The work is most often cited by research in Toxicology (190 citations), Organic Chemistry (1.6k citations), Pharmacology (431 citations), Molecular Biology (1.1k citations) and Oncology (356 citations). John A. Hadfield has collaborated with scholars based in United Kingdom, Netherlands and Italy. Frequent co-authors include Alan T. McGown, Nicholas J. Lawrence, Donald M. Watkin, Allan M. Jordan, Sylvie Ducki, David Rennison, Keira Gaukroger, D F L Watkin, Steven P. Nolan and AT McGown. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, The Lancet, British Journal of Cancer, Planta Medica and Journal of the Chemical Society Perkin Transactions 1.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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