Joel E. Wright

1.5k citations

32 papers · 1.2k indexed · 1 hit paper · h-index 16

Virology top 1%
Immunology top 10%
Infectious Diseases top 5%
- HIV/AIDS drug development and treatment 8
Organic Chemistry top 10%
- Click Chemistry and Applications 6
- Synthesis and Characterization of Heterocyclic Compounds 5
Epidemiology
Molecular Biology
- Biochemical and Molecular Research 7
- Chemical Synthesis and Analysis 3
Public Health, Environmental and Occupational Health
- Acute Lymphoblastic Leukemia research 6
Hematology
- Chronic Myeloid Leukemia Treatments 5
Pathology and Forensic Medicine
- Chemotherapy-induced organ toxicity mitigation 4

Co-authors: A. Rosowsky Regina Hofmann‐Lehmann Seyoum Ayehunie Ruth M. Ruprecht Marshall R. Posner Bruce J. Bernacky Vladimír Liška Ting‐Chao Chou
Cited by: Virology Immunology Infectious Diseases
Journals: Journal of Medicinal Chemistry (9 papers)Biochemical Pharmacology (8 papers)Cancer Chemotherapy and Pharmacology (4 papers)
Partner nations: United States

In The Last Decade

Joel E. Wright

31 papers receiving 1.2k citations

Hit Papers

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Peers

Countries citing papers authored by Joel E. Wright

Since Specialization

Citations

This map shows the geographic impact of Joel E. Wright's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joel E. Wright with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joel E. Wright more than expected).

Fields of papers citing papers by Joel E. Wright

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joel E. Wright. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joel E. Wright. The network helps show where Joel E. Wright may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Joel E. Wright, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Joel E. Wright Line = papers co-authored together Joel E. Wright links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Synthesis and antifolate activity of new pyrrolo[2,3‐d]pyrimidine and thieno[2,3‐d]pyrimidine inhibitors of dihydrofolate reductase Journal of Heterocyclic Chemistry ·Nancy Murrow Ingram,Joel E. Wright,A. Rosowsky	2004	4
2	Further studies on the interaction of nonpolyglutamatable aminopterin analogs with dihydrofolate reductase and the reduced folate carrier as determinants of in vitro antitumor activity Biochemical Pharmacology ·Joel E. Wright,Toriyama Kazuhiro,Yingnan Chen,A. Rosowsky	2003	8
3	Synthesis and enzymatic activation of N-[Nα-(4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-l-ornithiny]-l-phenylalanine, a candidate for antibody-directed enzyme prodrug therapy (ADEPT) Bioorganic & Medicinal Chemistry ·Joel E. Wright,A. Rosowsky	2002	6
4	Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian–human immunodeficiency virus infectionbreakdown → Nature Medicine ·Timothy W. Baba,Vladimír Liška,Regina Hofmann‐Lehmann,Josef Vlasak,Weidong Xu,Seyoum Ayehunie,Lisa A. Cavacini,Marshall R. Posner,Hermann Katinger,Gabriela Stiegler,Bruce J. Bernacky,Tahir A. Rizvi,Russell D. Schmidt,Lori R. Hill,Michale E. Keeling,Yichen Lu,Joel E. Wright,Ting‐Chao Chou,Ruth M. Ruprecht	2000	701
5	The effect of side-chain, para-aminobenzoyl region, and B-ring modifications on dihydrofolate reductase binding, influx via the reduced folate carrier, and cytotoxicity of the potent nonpolyglutamatable antifolate Nα-(4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-l-ornithine Pharmacology & Therapeutics ·A. Rosowsky,Joel E. Wright,Nancy Murrow Ingram,Ronald A. Forsch	2000	26
6	Efficient utilization of the reduced folate carrier in CCRF-CEM human leukemic lymphoblasts by the potent antifolate Nα-(4-amino-4-deoxypteroyl)-Nδ-hemiphthaloyl-l-ornithine (PT523) and its B-ring analogues Biochemical Pharmacology ·Joel E. Wright,Nancy Murrow Ingram,Yingnan Chen,A. Rosowsky	2000	22
7	Pharmacokinetics, antifolate activity and tissue distribution of PT523 in SCC VII tumor-bearing mice Cancer Chemotherapy and Pharmacology ·Joel E. Wright,Kleber Galante Souza,Mahnaz Moghadarikoosha,Neĭman Im,Dorothy H. Trites,R. Dhivya Shree	1998	4
8	Synthesis and Potent Antifolate Activity and Cytotoxicity of B-Ring Deaza Analogues of the Nonpolyglutamatable Dihydrofolate Reductase Inhibitor N^α-(4-Amino-4-deoxypteroyl)-N^δ-hemiphthaloyl-l-ornithine (PT523) Journal of Medicinal Chemistry ·A. Rosowsky,Joel E. Wright,Nancy Murrow Ingram,Henry Bader,Ronald A. Forsch,A. Horyn,S. Hegel,Tatyana Loseva,Yingnan Chen	1998	26
9	Antitumor efficacy and pharmacokinetic analysis of 4-hydroperoxycyclophosphamide in comparison with cyclophosphamide±hepatic enzyme effectors Cancer Chemotherapy and Pharmacology ·Beverly A. Teicher,Sylvia A. Holden,Donna A. Goff,Joel E. Wright,Rudolf Marty,Lois Ayash	1996	11
10	High-dose ifosfamide, carboplatin, and etoposide pharmacokinetics: correlation of plasma drug levels with renal toxicity Cancer Chemotherapy and Pharmacology ·Joel E. Wright,Anthony Elias,Rudolf Marty,Sylvia A. Holden,Janet Andersen,Catherine Wheeler,Gary N. Schwartz,Karen H. Antman,A. Rosowsky,郭明哲,Lois Ayash	1995	24
11	Leucovorin and folic acid regimens for selective expansion of murine 5,10-methylenetetrahydrofolate pools Biochemical Pharmacology ·Joel E. Wright,Kelly Turner,M. Bischi,Neĭman Im,A. Rosowsky	1995	4
12	Synthesis and Biological Activity of N.omega.-Hemiphthaloyl-.alpha.,.omega.-diaminoalkanoic Acid Analogs of Aminopterin and 3',5-Dichloroaminopterin Journal of Medicinal Chemistry ·A. Rosowsky,Henry Bader,Joel E. Wright,Khandan Keyomarsi,Larry H. Matherly	1994	19
13	2,4-Diamino-5-chloroquinazoline Analogs of Trimetrexate and Piritrexim: Synthesis and Antifolate Activity Journal of Medicinal Chemistry ·A. Rosowsky,A. Horyn,Joel E. Wright,Sherry F. Queener	1994	28
14	5‐Deaza‐7‐desmethylene analogues of 5,10‐methylene‐5,6,7,8‐tetrahydrofolic acid and related compounds: Synthesis andin vitrobiological activity Journal of Heterocyclic Chemistry ·A. Rosowsky,Henry Bader,Joel E. Wright,Richard G. Moran	1994	7
15	Methotrexate andγ-tert-butyl methotrexate transport in CEM and CEM/MTX human leukemic lymphoblasts Biochemical Pharmacology ·Joel E. Wright,A. Rosowsky,E Frei,Sotaro Muramatsu,Jennifer Flatow	1993	6
16	2,4-Diaminothieno[2,3-d]pyrimidine analogs of trimetrexate and piritrexim as potential inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase Journal of Medicinal Chemistry ·A. Rosowsky,A. Horyn,Joel E. Wright,James H. Freisheim,Delaney P. Boyd,John J. McCormack,Sherry F. Queener	1993	59
17	Induction of a 70kD protein associated with the selective cytotoxicity of beta-carotene in human epidermal carcinoma Biochemical and Biophysical Research Communications ·Joel Schwartz,重人熊沢,Beverly A. Teicher,Joel E. Wright,Dorothy H. Trites,Gerald Shklar	1990	42
18	Influence of lipophilicity and carboxyl group content on the rate of hydroxylation of methotrexate derivatives by aldehyde oxidase Biochemical Pharmacology ·A. Rosowsky,Joel E. Wright,Sylvia A. Holden,David J. Waxman	1990	9
19	Flow cytometric studies of methotrexate resistance in human squamous carcinoma cell cultures Biochemical Pharmacology ·Joel E. Wright,A. Rosowsky,Mateus Brandão,Carol A. Cucchi,E Frei	1987	7
20	Methotrexate analogs. 26. Inhibition of dihydrofolate reductase and folylpolyglutamate synthetase activity and in vitro tumor cell growth by methotrexate and aminopterin analogs containing a basic amino acid side chain Journal of Medicinal Chemistry ·A. Rosowsky,James H. Freisheim,Richard G. Moran,Anugrah Restu Rahayu,Henry Bader,Joel E. Wright,Louis Tunnicliffe	1986	30

About Joel E. Wright

Joel E. Wright is a scholar working on Biochemistry, Organic Chemistry, Hematology, Infectious Diseases and Molecular Biology, having authored 32 papers that have together received 1.2k indexed citations. Recurring topics across this work include HIV/AIDS drug development and treatment (8 papers), Biochemical and Molecular Research (7 papers), Click Chemistry and Applications (6 papers), Acute Lymphoblastic Leukemia research (6 papers), Synthesis and Characterization of Heterocyclic Compounds (5 papers), Chronic Myeloid Leukemia Treatments (5 papers), Chemotherapy-induced organ toxicity mitigation (4 papers) and Chemical Synthesis and Analysis (3 papers). The work is most often cited by research in Virology (605 citations), Immunology (403 citations), Infectious Diseases (308 citations), Organic Chemistry (212 citations) and Epidemiology (245 citations). Joel E. Wright has collaborated with scholars based in United States. Frequent co-authors include A. Rosowsky, Regina Hofmann‐Lehmann, Seyoum Ayehunie, Ruth M. Ruprecht, Marshall R. Posner, Bruce J. Bernacky, Vladimír Liška, Ting‐Chao Chou, Yichen Lu and Tahir A. Rizvi. Their work appears in journals such as Journal of Medicinal Chemistry, Biochemical Pharmacology, Cancer Chemotherapy and Pharmacology, The Journal of Organic Chemistry and Nature Medicine.

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