Edwin Clark

11.0k total citations · 4 hit papers
61 papers, 8.4k citations indexed

About

Edwin Clark is a scholar working on Molecular Biology, Oncology and Hematology. According to data from OpenAlex, Edwin Clark has authored 61 papers receiving a total of 8.4k indexed citations (citations by other indexed papers that have themselves been cited), including 26 papers in Molecular Biology, 20 papers in Oncology and 17 papers in Hematology. Recurrent topics in Edwin Clark's work include Cell Adhesion Molecules Research (10 papers), Chronic Myeloid Leukemia Treatments (8 papers) and Chronic Lymphocytic Leukemia Research (7 papers). Edwin Clark is often cited by papers focused on Cell Adhesion Molecules Research (10 papers), Chronic Myeloid Leukemia Treatments (8 papers) and Chronic Lymphocytic Leukemia Research (7 papers). Edwin Clark collaborates with scholars based in United States, United Kingdom and Germany. Edwin Clark's co-authors include Joan S. Brugge, Richard O. Hynes, Eric S. Lander, Todd R. Golub, Marc Symons, W G King, Sanford J. Shattil, Tai W. Wong, Fei Huang and Karen A. Reeves and has published in prestigious journals such as Nature, Science and Journal of Biological Chemistry.

In The Last Decade

Edwin Clark

60 papers receiving 8.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Integrins and Signal Transduction Pathways: the Road Taken

1995 2.6k citations Edwin Clark, Joan S. Brugge profile →
Genomic analysis of metastasis reveals an essential role for RhoC

2000 1.2k citations Edwin Clark, Todd R. Golub et al. Nature profile →
Expression of Epiregulin and Amphiregulin and K-ras Mutation Status Predict Disease Control in Metastatic Colorectal Cancer Patients Treated With Cetuximab

2007 898 citations Shirin Khambata‐Ford, Christopher R. Garrett et al. Journal of Clinical Oncology profile →
Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases

1998 513 citations Edwin Clark, Joan S. Brugge et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Edwin Clark United States	30	4.1k	2.6k	2.5k	1.9k	1.7k	61	8.4k
Kairbaan Hodivala‐Dilke United Kingdom	50	5.3k 1.3×	3.2k 1.3×	2.0k 0.8×	1.7k 0.9×	1.6k 1.0×	107	9.7k
Clare M. Isacke United Kingdom	57	4.9k 1.2×	1.3k 0.5×	2.5k 1.0×	2.0k 1.1×	1.8k 1.1×	141	8.5k
Elena I. Deryugina United States	46	3.8k 0.9×	1.8k 0.7×	3.6k 1.4×	1.6k 0.9×	3.8k 2.3×	71	9.4k
Jorge Filmus Canada	54	7.8k 1.9×	1.5k 0.6×	2.7k 1.1×	3.5k 1.9×	2.0k 1.2×	103	11.8k
Judith A. Varner United States	44	4.7k 1.1×	3.3k 1.3×	2.8k 1.1×	1.0k 0.5×	1.7k 1.0×	82	9.2k
Dwayne G. Stupack United States	46	4.4k 1.1×	2.3k 0.9×	1.5k 0.6×	1.5k 0.8×	1.2k 0.7×	109	7.3k
Richard E.B. Seftor United States	54	6.4k 1.6×	1.7k 0.7×	3.1k 1.2×	1.6k 0.9×	3.0k 1.8×	101	9.4k
Chuanyue Wu United States	58	5.8k 1.4×	5.4k 2.1×	1.2k 0.5×	3.8k 2.1×	1.5k 0.9×	177	10.8k
Jasti S. Rao United States	54	4.4k 1.1×	1.2k 0.5×	2.4k 0.9×	743 0.4×	3.8k 2.3×	169	8.3k
Elisabeth A. Seftor United States	63	9.5k 2.3×	2.1k 0.8×	4.7k 1.9×	2.0k 1.1×	4.8k 2.9×	124	13.9k

Countries citing papers authored by Edwin Clark

Since Specialization

Citations

This map shows the geographic impact of Edwin Clark's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edwin Clark with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edwin Clark more than expected).

Fields of papers citing papers by Edwin Clark

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edwin Clark. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edwin Clark. The network helps show where Edwin Clark may publish in the future.

Co-authorship network of co-authors of Edwin Clark

This figure shows the co-authorship network connecting the top 25 collaborators of Edwin Clark. A scholar is included among the top collaborators of Edwin Clark based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Edwin Clark. Edwin Clark is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Schuller, Alwin G., Evan Barry, Rhys D.O. Jones, et al.. (2015). The MET Inhibitor AZD6094 (Savolitinib, HMPL-504) Induces Regression in Papillary Renal Cell Carcinoma Patient–Derived Xenograft Models. Clinical Cancer Research. 21(12). 2811–2819. 57 indexed citations

Baker, Joffre, Debjani Dutta, Drew Watson, et al.. (2011). Tumour gene expression predicts response to cetuximab in patients with KRAS wild-type metastatic colorectal cancer. British Journal of Cancer. 104(3). 488–495. 81 indexed citations

Efferson, Clay L., Christopher T. Winkelmann, Christopher Ware, et al.. (2010). Downregulation of Notch Pathway by a γ-Secretase Inhibitor Attenuates AKT/Mammalian Target of Rapamycin Signaling and Glucose Uptake in an ERBB2 Transgenic Breast Cancer Model. Cancer Research. 70(6). 2476–2484. 76 indexed citations

Huang, Fei, Ann Greer, Warren Hurlburt, et al.. (2008). The Mechanisms of Differential Sensitivity to an Insulin-like Growth Factor-1 Receptor Inhibitor (BMS-536924) and Rationale for Combining with EGFR/HER2 Inhibitors. Cancer Research. 69(1). 161–170. 137 indexed citations

Eskandarpour, Malihe, Fei Huang, Karen A. Reeves, Edwin Clark, & Johan Hansson. (2008). Oncogenic NRAS has multiple effects on the malignant phenotype of human melanoma cells cultured in vitro. International Journal of Cancer. 124(1). 16–26. 47 indexed citations

Huang, Fei, Karen A. Reeves, Xia Han, et al.. (2007). Identification of Candidate Molecular Markers Predicting Sensitivity in Solid Tumors to Dasatinib: Rationale for Patient Selection. Cancer Research. 67(5). 2226–2238. 274 indexed citations

Garrett, Christopher, Edwin Clark, Mark Basik, et al.. (2007). Expression of epiregulin and amphiregulin and K-RAS mutation status predict disease control in metastatic colorectal cancer patients treated with cetuximab (Erbitux ®). Cancer Research. 67. 5670–5670. 3 indexed citations

Wang, Xi-De, Karen A. Reeves, Feng Luo, et al.. (2007). Identification of candidate predictive and surrogate molecular markers for dasatinib in prostate cancer: rationale for patient selection and efficacy monitoring. Genome biology. 8(11). R255–R255. 73 indexed citations

Khambata‐Ford, Shirin, Christopher R. Garrett, Neal J. Meropol, et al.. (2007). Expression of Epiregulin and Amphiregulin and K-ras Mutation Status Predict Disease Control in Metastatic Colorectal Cancer Patients Treated With Cetuximab. Journal of Clinical Oncology. 25(22). 3230–3237. 898 indexed citations breakdown →

10.

Huang, Xin, Tai W. Wong, Suso Platero, et al.. (2006). Preclinical discovery and clinical validation of predictive markers of response to cetuximab (Erbitux™) in metastatic colorectal cancer. Cancer Research. 66. 950–950. 3 indexed citations

11.

Lutz, E.M., Chris Mackenzie, John A. Morrow, et al.. (2006). Chimaeric VIP2/PACAP Receptors Reveal That Agonist Pharmacology but not Signal Transduction Is Determined by Extracellular Domain 1. Annals of the New York Academy of Sciences. 805(1). 574–578.

12.

Symmans, W. Fraser, Mark Ayers, Edwin Clark, et al.. (2003). Total RNA yield and microarray gene expression profiles from fine‐needle aspiration biopsy and core‐needle biopsy samples of breast carcinoma. Cancer. 97(12). 2960–2971. 140 indexed citations

13.

Clark, Edwin, Todd R. Golub, Eric S. Lander, & Richard O. Hynes. (2000). Genomic analysis of metastasis reveals an essential role for RhoC. Nature. 406(6795). 532–535. 1193 indexed citations breakdown →

14.

Clark, Edwin & Richard O. Hynes. (1997). 1997 keystone symposium on signal transduction by cell adhesion receptors. Biochimica et Biophysica Acta (BBA) - Reviews on Cancer. 1333(3). R9–R16. 20 indexed citations

15.

Clark, Edwin & Richard O. Hynes. (1996). Ras Activation Is Necessary for Integrin-mediated Activation of Extracellular Signal-regulated Kinase 2 and Cytosolic Phospholipase A2 but Not for Cytoskeletal Organization. Journal of Biological Chemistry. 271(25). 14814–14818. 147 indexed citations

16.

Clark, Edwin, Sanford J. Shattil, & Joan S. Brugge. (1994). Regulation of protein tyrosine kinases in platelets. Trends in Biochemical Sciences. 19(11). 464–469. 140 indexed citations

17.

Clark, Edwin, Sanford J. Shattil, Mark H. Ginsberg, Joseph B. Bolen, & Joan S. Brugge. (1994). Regulation of the protein tyrosine kinase pp72syk by platelet agonists and the integrin alpha IIb beta 3.. Journal of Biological Chemistry. 269(46). 28859–28864. 201 indexed citations

18.

Clark, Edwin & Joan S. Brugge. (1993). Tyrosine phosphorylation in platelets. Trends in Cardiovascular Medicine. 3(6). 218–227. 26 indexed citations

19.

Clark, Edwin & V. M.‐Y. Lee. (1991). Dynamics of mammalian high‐molecular‐weight neurofilament subunit phosphorylation in cultured rat sympathetic neurons. Journal of Neuroscience Research. 30(1). 116–123. 20 indexed citations

20.

Clark, Edwin & Virginia M.‐Y. Lee. (1991). The Differential Role of Protein Kinase C Isozyme in the Rapid Induction of Neurofilament Phosphorylation by Nerve Growth Factor and Phorbol Esters in PC12 Cells. Journal of Neurochemistry. 57(3). 802–810. 23 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact