Jeffrey V. Leyton

1.1k citations

34 papers · 856 indexed · h-index 17

Radiology, Nuclear Medicine and Imaging top 5%
- Radiopharmaceutical Chemistry and Applications 14
- Monoclonal and Polyclonal Antibodies Research 11
- Medical Imaging Techniques and Applications 3
Oncology top 10%
- HER2/EGFR in Cancer Research 9
- Cancer Immunotherapy and Biomarkers 4
- Cancer Cells and Metastasis 4
Structural Biology
Surfaces, Coatings and Films top 10%
Immunology
- Immunotherapy and Immune Responses 5
Pulmonary and Respiratory Medicine
- Prostate Cancer Treatment and Research 4

Co-authors: Anna M. Wu Robert E. Reiter Tove Olafsen Raymond M. Reilly Chung-Cheng Lee Guodong Sui Hsian‐Rong Tseng Jinyi Wang
Cited by: Radiology, Nuclear Medicine and Imaging Oncology Structural Biology
Journals: Chemical Society Reviews (1 paper)SHILAP Revista de lepidopterología (1 paper)Analytical Chemistry (1 paper)
Partner nations: Canada United States Australia

In The Last Decade

Jeffrey V. Leyton

32 papers receiving 834 citations

Peers

Countries citing papers authored by Jeffrey V. Leyton

Since Specialization

Citations

This map shows the geographic impact of Jeffrey V. Leyton's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffrey V. Leyton with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffrey V. Leyton more than expected).

Fields of papers citing papers by Jeffrey V. Leyton

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffrey V. Leyton. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffrey V. Leyton. The network helps show where Jeffrey V. Leyton may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jeffrey V. Leyton, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jeffrey V. Leyton Line = papers co-authored together Jeffrey V. Leyton links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Disitamab vedotin in preclinical models of HER2-positive breast and gastric cancers resistant to trastuzumab emtansine and trastuzumab deruxtecan Translational Oncology ·Negar Pourjamal,Vadim Le Joncour,György Vereb,Cilla Honkamäki,Jorma Isola,Jeffrey V. Leyton,Pirjo Laakkonen,Heikki Joensuu,Márk Barok	2025	1
2	Integrating Biochemical and Computational Approaches Reveal Structural Insights in Trastuzumab scFv-Fc Antibody Engineering Biomolecules ·Olga Bednova,Jessica Pougoue Ketchemen,Hazem Mslati,Márk Barok,Heikki Joensuu,Natalie Zeytuni,Francesco Gentile,Léon Sanche,Humphrey Fonge,Jeffrey V. Leyton	2025	0
3	A Novel Proteomic Method Reveals NLS Tagging of T-DM1 Contravenes Classical Nuclear Transport in a Model of HER2-Positive Breast Cancer Molecular Therapy — Methods & Clinical Development ·Vincent Lacasse,Simon Beaudoin,Steve Jean,Jeffrey V. Leyton	2020	10
4	A preclinical PET dual-tracer imaging protocol for ER and HER2 phenotyping in breast cancer xenografts EJNMMI Research ·Michel Paquette,Serge Phoenix,Christine Lawson,Brigitte Guérin,Roger Lecomte,Lee‐Hwa Tai,Éric Turcotte,Jeffrey V. Leyton	2020	4
5	Improving Receptor-Mediated Intracellular Access and Accumulation of Antibody Therapeutics—The Tale of HER2 SHILAP Revista de lepidopterología ·Jeffrey V. Leyton	2020	23
6	Initial Evaluation of Antibody-conjugates Modified with Viral-derived Peptides for Increasing Cellular Accumulation and Improving Tumor Targeting Journal of Visualized Experiments ·Simon Beaudoin,Michel Paquette,Laurent Fafard-Couture,Mylene A. Tremblay,Roger Lecomte,Brigitte Guérin,Jeffrey V. Leyton	2018	3
7	CD16⁺NK-92 and anti-CD123 monoclonal antibody prolongs survival in primary human acute myeloid leukemia xenografted mice Haematologica ·Brent A. Williams,Xinghua Wang,Jeffrey V. Leyton,Sonam Maghera,Bishoy Deif,Raymond M. Reilly,Mark D. Minden,Armand Keating	2018	18
8	Targeting IL-5Rα with antibody-conjugates reveals a strategy for imaging and therapy for invasive bladder cancer OncoImmunology ·Michel Paquette,Luis-Guillermo Vilera-Perez,Simon Beaudoin,Nadia Ekindi‐Ndongo,Pierre-Luc Boudreaut,Marc‐André Bonin,Marie‐Claude Battista,M’hamed Bentourkia,Angel F. López,Roger Lecomte,Éric Marsault,Brigitte Guérin,Robert Sabbagh,Jeffrey V. Leyton	2017	16
9	BODIPY-17α-ethynylestradiol conjugates: Synthesis, fluorescence properties and receptor binding affinities Bioorganic & Medicinal Chemistry Letters ·Samira Osati,Hesham Ali,Fernanda Marques,Michel Paquette,Simon Beaudoin,Brigitte Guérin,Jeffrey V. Leyton,Johan E. van Lier	2016	17
10	Auger electron-emitting 111 In-DTPA-NLS-CSL360 radioimmunoconjugates are cytotoxic to human acute myeloid leukemia (AML) cells displaying the CD123 + /CD131 − phenotype of leukemia stem cells Applied Radiation and Isotopes ·Catherine A. Gao,Jeffrey V. Leyton,Aaron D. Schimmer,Mark D. Minden,Raymond M. Reilly	2015	13
11	A radiolabeled antibody targeting CD123+ leukemia stem cells – initial radioimmunotherapy studies in NOD/SCID mice engrafted with primary human AML Leukemia Research Reports ·Jeffrey V. Leyton,Catherine A. Gao,Brent A. Williams,Armand Keating,Mark D. Minden,Raymond M. Reilly	2015	18
12	MicroSPECT/CT imaging of primary human AML engrafted into the bone marrow and spleen of NOD/SCID mice using 111In-DTPA-NLS-CSL360 radioimmunoconjugates recognizing the CD123+/CD131− epitope expressed by leukemia stem cells Leukemia Research ·Jeffrey V. Leyton,Brent A. Williams,Catherine A. Gao,Armand Keating,Mark D. Minden,Raymond M. Reilly	2014	10
13	The human polynucleotide kinase/phosphatase (hPNKP) inhibitor A12B4C3 radiosensitizes human myeloid leukemia cells to Auger electron-emitting anti-CD123 111In-NLS-7G3 radioimmunoconjugates Nuclear Medicine and Biology ·Arman Zereshkian,Jeffrey V. Leyton,Zhongli Cai,Dane Bergstrom,Michael Weinfeld,Raymond M. Reilly	2014	20
14	111In-Bn-DTPA-nimotuzumab with/without modification with nuclear translocation sequence (NLS) peptides: an Auger electron-emitting radioimmunotherapeutic agent for EGFR-positive and trastuzumab (Herceptin)-resistant breast cancer Breast Cancer Research and Treatment ·Aisha Fasih,Humphrey Fonge,Zhongli Cai,Jeffrey V. Leyton,Ilia Tikhomirov,Susan J. Done,Raymond M. Reilly	2012	41
15	Auger Electron Radioimmunotherapeutic Agent Specific for the CD123⁺/CD131⁻ Phenotype of the Leukemia Stem Cell Population Journal of Nuclear Medicine ·Jeffrey V. Leyton,Meiduo Hu,Catherine A. Gao,Patricia V. Turner,John E. Dick,Mark D. Minden,Raymond M. Reilly	2011	37
16	An affinity matured minibody for PET imaging of prostate stem cell antigen (PSCA)-expressing tumors European Journal of Nuclear Medicine and Molecular Imaging ·Eric J. Lepin,Jeffrey V. Leyton,Yu Zhou,Tove Olafsen,Felix B. Salazar,Katelyn E. McCabe,Scott Hahm,James D. Marks,Robert E. Reiter,Anna M. Wu	2010	50
17	Engineered humanized diabodies for microPET imaging of prostate stem cell antigen-expressing tumors Protein Engineering Design and Selection ·Jeffrey V. Leyton,Tove Olafsen,Mark A. Sherman,Karl B. Bauer,Paola Aghajanian,Robert E. Reiter,Anna M. Wu	2008	39
18	Targeting, Imaging, and Therapy Using a Humanized Antiprostate Stem Cell Antigen (PSCA) Antibody Journal of Immunotherapy ·Tove Olafsen,Zhennan Gu,Mark A. Sherman,Jeffrey V. Leyton,Michael E. Witkosky,John E. Shively,Andrew Raubitschek,Sherie L. Morrison,Anna M. Wu,Robert E. Reiter	2007	61
19	Solution-Phase Surface Modification in Intact Poly(dimethylsiloxane) Microfluidic Channels Analytical Chemistry ·Guodong Sui,Jinyi Wang,Chung-Cheng Lee,Weixing Lu,Stephanie P. Lee,Jeffrey V. Leyton,Anna M. Wu,Hsian‐Rong Tseng	2006	191
20	Mononuclear cell accumulation and plasma protein extravasation (PPE) during induction, remission and re-challenge of experimental allergic encephalomyelitis in the rat Journal of the Neurological Sciences ·Vivian M. Rumjanek,Jeffrey V. Leyton,J. Morley	1984	9

About Jeffrey V. Leyton

Jeffrey V. Leyton is a scholar working on Radiology, Nuclear Medicine and Imaging, Oncology and Immunology, having authored 34 papers that have together received 856 indexed citations. Recurring topics across this work include Radiopharmaceutical Chemistry and Applications (14 papers), Monoclonal and Polyclonal Antibodies Research (11 papers), HER2/EGFR in Cancer Research (9 papers), Immunotherapy and Immune Responses (5 papers), Cancer Immunotherapy and Biomarkers (4 papers), Cancer Cells and Metastasis (4 papers), Prostate Cancer Treatment and Research (4 papers) and Medical Imaging Techniques and Applications (3 papers). The work is most often cited by research in Radiology, Nuclear Medicine and Imaging (317 citations), Oncology (288 citations) and Structural Biology (11 citations). Jeffrey V. Leyton has collaborated with scholars based in Canada, United States and Australia. Frequent co-authors include Anna M. Wu, Robert E. Reiter, Tove Olafsen, Raymond M. Reilly, Chung-Cheng Lee, Guodong Sui, Hsian‐Rong Tseng, Jinyi Wang, Weixing Lu and Andrew W. Craig. Their work appears in journals such as Chemical Society Reviews, SHILAP Revista de lepidopterología and Analytical Chemistry.

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