Jeffrey J. Hale

5.8k citations

52 papers · 3.0k indexed · 1 hit paper · h-index 24

Molecular Biology top 5%
- Sphingolipid Metabolism and Signaling 15
- Receptor Mechanisms and Signaling 10
- Lipid Membrane Structure and Behavior 8
- Chemical Synthesis and Analysis 5
- Protein Kinase Regulation and GTPase Signaling 4
Immunology top 5%
Organic Chemistry top 5%
- Carbohydrate Chemistry and Synthesis 7
Neurology top 5%
Physiology top 5%
Cellular and Molecular Neuroscience
- Neuropeptides and Animal Physiology 8
Pharmacology
- Cannabis and Cannabinoid Research 5

Co-authors: Suzanne Mandala James A. Milligan Mark Rosenbach James D. Bergstrom Richard Hajdu Gan-Ju Shei Deborah Card Hugh Rosen
Cited by: Molecular Biology Immunology Organic Chemistry
Partner nations: United States Netherlands India

In The Last Decade

Jeffrey J. Hale

51 papers receiving 2.9k citations

Hit Papers

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Peers

Countries citing papers authored by Jeffrey J. Hale

Since Specialization

Citations

This map shows the geographic impact of Jeffrey J. Hale's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffrey J. Hale with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffrey J. Hale more than expected).

Fields of papers citing papers by Jeffrey J. Hale

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffrey J. Hale. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffrey J. Hale. The network helps show where Jeffrey J. Hale may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jeffrey J. Hale, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jeffrey J. Hale Line = papers co-authored together Jeffrey J. Hale links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Design, synthesis, and biological evaluation of aminopyrazine derivatives as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2) Songnian Lin,Sunita Malkani,Matthew Lombardo,Lihu Yang,Sander G. Mills,Kevin T. Chapman,James E. Thompson,Wen Xiao Zhang,Ruixiu Wang,Rose M. Cubbon,Edward A. O’Neill,Jeffrey J. Hale	2015	9
2	Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors Thomas H. Graham,Min Shu,Andreas Verras,Chen Qing,Margarita García‐Calvo,Xiaohua Li,JeanMarie Lisnock,Xinchun Tong,Elaine Tung,Judyann Wiltsie,Jeffrey J. Hale,Shirly Pinto,Dong‐Ming Shen	2014	15
3	MK-7128, a novel CB1 receptor inverse agonist, improves scopolamine-induced learning and memory deficits in mice Gregory M. Dillon,Laura S. Lubbers,Mitchell T. Ferguson,Julie Lao,Ruey-Ruey C. Huang,Jing Chen Xiao,Tung M. Fong,Jeffrey J. Hale,Kathleen M. Rupprecht,Shouwu Miao,Blake A. Rowe,Thomas Kornecook,Jean‐Cosme Dodart	2011	9
4	Dihydro-pyrano[2,3-b]pyridines and tetrahydro-1,8-naphthyridines as CB1 receptor inverse agonists: Synthesis, SAR and biological evaluation Christina B. Madsen-Duggan,John S. Debenham,Thomas F. Walsh,Lin Yan,Pei Huo,Junying Wang,Xinchun Tong,Julie Lao,Tung M. Fong,Jing Chen Xiao,Cathy R.-R.C. Huang,Chun-Pyn Shen,D. Sloan Stribling,Lauren P. Shearman,Alison M. Strack,Mark T. Goulet,Jeffrey J. Hale	2010	8
5	Discovery ofN-[(4R)-6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a Novel Cannabinoid-1 Receptor (CB1R) Inverse Agonist for the Treatment of Obesity Lin Yan,Pei Huo,John S. Debenham,Christina B. Madsen-Duggan,Julie Lao,Richard Z. Chen,Jing Chen Xiao,Chun-Pyn Shen,D. Sloan Stribling,Lauren P. Shearman,Alison M. Strack,Nancy N. Tsou,Richard G. Ball,Junying Wang,Xinchun Tong,Thomas J. Bateman,Vijay Reddy,Tung M. Fong,Jeffrey J. Hale	2010	15
6	Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia Lin Yan,Vincent J. Colandrea,Jeffrey J. Hale	2010	72
7	Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation John S. Debenham,Christina B. Madsen-Duggan,Junying Wang,Xinchun Tong,Julie Lao,Tung M. Fong,Marie‐Therese Schaeffer,Jing Chen Xiao,Cathy C. R.-R. Huang,Chun-Pyn Shen,D. Sloan Stribling,Lauren P. Shearman,Alison M. Strack,D. Euan MacIntyre,Jeffrey J. Hale,Thomas F. Walsh	2009	16
8	Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists Wu Du,James P. Jewell,Linus S. Lin,Vincent J. Colandrea,Jing Chen Xiao,Julie Lao,Chun-Pyn Shen,Thomas J. Bateman,Vijay Reddy,Sookhee Ha,Shrenik K. Shah,Tung M. Fong,Jeffrey J. Hale,William K. Hagmann	2009	7
9	Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2) Songnian Lin,Matthew Lombardo,Sunita Malkani,Jeffrey J. Hale,Sander G. Mills,Kevin T. Chapman,James E. Thompson,Wen Xiao Zhang,Ruixiu Wang,Rose M. Cubbon,Edward A. O’Neill,Silvi Luell,Ester Carballo‐Jane,Lihu Yang	2009	18
10	Identification of Leu276 of the S1P1 Receptor and Phe263 of the S1P3 Receptor in Interaction with Receptor Specific Agonists by Molecular Modeling, Site-Directed Mutagenesis, and Affinity Studies Qiaolin Deng,Joseph Clemas,Gary Chrebet,Paul Fischer,Jeffrey J. Hale,Zhen Li,Sander G. Mills,James D. Bergstrom,Suzanne Mandala,Ralph Mosley,Stephen A. Parent	2006	32
11	Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor Petr Váchal,Leslie M. Toth,Jeffrey J. Hale,Lin Yan,Sander G. Mills,Gary Chrebet,Carol A. Koehane,Richard Hajdu,James A. Milligan,Mark Rosenbach,Suzanne Mandala	2006	29
12	Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes Lin Yan,Pei Huo,George Doherty,Lesile Toth,Jeffrey J. Hale,Sander G. Mills,Richard Hajdu,Carol Keohane,Mark Rosenbach,James A. Milligan,Gan-Ju Shei,Gary Chrebet,James D. Bergstrom,Deborah Card,Elizabeth J. Quackenbush,Alexandra Wickham,Suzanne Mandala	2006	15
13	Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720 Jeffrey J. Hale,William Neway,Sander G. Mills,Richard Hajdu,Carol Keohane,Mark Rosenbach,James A. Milligan,Gan-Ju Shei,Gary Chrebet,James D. Bergstrom,Deborah Card,Gloria C. Koo,Sam L. Koprak,Jesse J. Jackson,Hugh Rosen,Suzanne Mandala	2004	64
14	Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720 Jeffrey J. Hale,Lin Yan,William Neway,Richard Hajdu,James D. Bergstrom,James A. Milligan,Gan-Ju Shei,Gary Chrebet,Rosemary Thornton,Deborah Card,Mark Rosenbach,HughRosen,Suzanne Mandala	2004	39
15	Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists Jeffrey J. Hale,George Doherty,Leslie M. Toth,Sander G. Mills,Richard Hajdu,Carol Keohane,Mark Rosenbach,James A. Milligan,Gan-Ju Shei,Gary Chrebet,James D. Bergstrom,Deborah Card,Michael J. Forrest,Shu-Yu Sun,Sarah J. West,Huijuan Xie,Naomi Nomura,Hugh Rosen,Suzanne Mandala	2004	39
16	Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice Michael Webb,Chui‐Se Tham,Fen‐Fen Lin,Karen Lariosa‐Willingham,Naichen Yu,Jeffrey J. Hale,Suzanne Mandala,Jerold Chun,Tadimeti S. Rao	2004	194
17	Characterization of the binding and activity of a high affinity, pseudoirreversible morpholino tachykinin NK1 receptor antagonist Margaret A. Cascieri,Elżbieta Ber,Tung M. Fong,Jeffrey J. Hale,Frank S Tang,Lin‐Lin Shiao,Sander G. Mills,Malcolm MacCoss,Sharon Sadowski,Michael R. Tota,Catherine D. Strader	1997	8
18	In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists N.M.J. Rupniak,F.D. Tattersall,Angela Williams,Wayne Rycroft,Emma Carlson,Margaret A. Cascieri,Sharon Sadowski,Elżbieta Ber,Jeffrey J. Hale,Sander G. Mills,Malcolm MacCoss,Eileen M. Seward,Ian T. Huscroft,Simon N. Owen,Christopher J. Swain,R.G. Hill,Richard Hargreaves	1997	88
19	Mechanism of inhibition of human leukocyte elastase by monocyclic .beta.-lactams Renee M. Chabin,B. G. Green,Philip A. Gale,Alan L. Maycock,Hazel Weston,Conrad P. Dorn,Paul E. Finke,W. K. HAGMANN,Jeffrey J. Hale	1993	19
20	Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones S. K. Shah,Conrad P. Dorn,P E Finke,Jeffrey J. Hale,W. K. HAGMANN,Karen A. Brause,Gilbert O. Chandler,A L Kissinger,Bonnie M. Ashe	1992	63

About Jeffrey J. Hale

Jeffrey J. Hale is a scholar working on Cellular and Molecular Neuroscience, Virology and Molecular Biology, having authored 52 papers that have together received 3.0k indexed citations. Recurring topics across this work include Sphingolipid Metabolism and Signaling (15 papers), Receptor Mechanisms and Signaling (10 papers), Neuropeptides and Animal Physiology (8 papers), Lipid Membrane Structure and Behavior (8 papers), Carbohydrate Chemistry and Synthesis (7 papers), Chemical Synthesis and Analysis (5 papers), Cannabis and Cannabinoid Research (5 papers) and Protein Kinase Regulation and GTPase Signaling (4 papers). The work is most often cited by research in Molecular Biology (2.0k citations), Immunology (563 citations) and Organic Chemistry (650 citations). Jeffrey J. Hale has collaborated with scholars based in United States, Netherlands and India. Frequent co-authors include Suzanne Mandala, James A. Milligan, Mark Rosenbach, James D. Bergstrom, Richard Hajdu, Gan-Ju Shei, Deborah Card, Hugh Rosen, Christopher L. Lynch and Rosemary Thornton.

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