Jeffrey J. Hale

5.8k citations

52 papers · 3.0k indexed · 1 hit paper · h-index 24

Molecular Biology top 5%
Organic Chemistry top 5%
Immunology top 5%
Cell Biology top 5%
Cellular and Molecular Neuroscience top 5%

Co-authors: Suzanne Mandala James A. Milligan Mark Rosenbach James D. Bergstrom Richard Hajdu Gan-Ju Shei Deborah Card Hugh Rosen
Topics: Sphingolipid Metabolism and Signaling (15 papers)Receptor Mechanisms and Signaling (10 papers)Neuropeptides and Animal Physiology (8 papers)
Cited by: Molecular Biology Immunology Organic Chemistry
Journals: Science Proceedings of the National Academy of Sciences Biochemistry
Partner nations: United States Netherlands India

In The Last Decade

Jeffrey J. Hale

51 papers receiving 2.9k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Alteration of Lymphocyte Trafficking by Sphingosine-1-Phosphate Receptor Agonists

2002 1.4k citations Suzanne Mandala, Richard Hajdu et al. profile →

Peers

Countries citing papers authored by Jeffrey J. Hale

Since Specialization

Citations

This map shows the geographic impact of Jeffrey J. Hale's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jeffrey J. Hale with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jeffrey J. Hale more than expected).

Fields of papers citing papers by Jeffrey J. Hale

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jeffrey J. Hale. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jeffrey J. Hale. The network helps show where Jeffrey J. Hale may publish in the future.

Co-authorship network of co-authors of Jeffrey J. Hale

This figure shows the co-authorship network connecting the top 25 collaborators of Jeffrey J. Hale. A scholar is included among the top collaborators of Jeffrey J. Hale based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jeffrey J. Hale. Jeffrey J. Hale is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Design, synthesis, and biological evaluation of aminopyrazine derivatives as inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2) 2015 ·Bioorganic & Medicinal Chemistry Letters ·Songnian Lin,(unknown),(unknown),Lihu Yang,Sander G. Mills,Kevin T. Chapman,James E. Thompson,(unknown),(unknown),Rose M. Cubbon,Edward A. O’Neill,Jeffrey J. Hale	9
2	Pyrazoles as non-classical bioisosteres in prolylcarboxypeptidase (PrCP) inhibitors 2014 ·Bioorganic & Medicinal Chemistry Letters ·Thomas H. Graham,Min Shu,Andreas Verras,Chen Qing,Margarita García‐Calvo,Xiaohua Li,JeanMarie Lisnock,Xinchun Tong,(unknown),Judyann Wiltsie,Jeffrey J. Hale,Shirly Pinto,Dong‐Ming Shen	15
3	MK-7128, a novel CB1 receptor inverse agonist, improves scopolamine-induced learning and memory deficits in mice 2011 ·Behavioural Pharmacology ·Gregory M. Dillon,Laura S. Lubbers,(unknown),Julie Lao,Ruey-Ruey C. Huang,Jing Chen Xiao,Tung M. Fong,Jeffrey J. Hale,Kathleen M. Rupprecht,(unknown),Blake A. Rowe,Thomas Kornecook,Jean‐Cosme Dodart	9
4	Dihydro-pyrano[2,3-b]pyridines and tetrahydro-1,8-naphthyridines as CB1 receptor inverse agonists: Synthesis, SAR and biological evaluation 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),John S. Debenham,Thomas F. Walsh,Lin Yan,(unknown),Junying Wang,Xinchun Tong,Julie Lao,Tung M. Fong,Jing Chen Xiao,(unknown),Chun-Pyn Shen,D. Sloan Stribling,Lauren P. Shearman,Alison M. Strack,Mark T. Goulet,Jeffrey J. Hale	8
5	Discovery ofN-[(4R)-6-(4-Chlorophenyl)-7-(2,4-dichlorophenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridin-4-yl]-5-methyl-1H-pyrazole-3-carboxamide (MK-5596) as a Novel Cannabinoid-1 Receptor (CB1R) Inverse Agonist for the Treatment of Obesity 2010 ·Journal of Medicinal Chemistry ·Lin Yan,(unknown),John S. Debenham,(unknown),Julie Lao,Richard Z. Chen,Jing Chen Xiao,Chun-Pyn Shen,D. Sloan Stribling,Lauren P. Shearman,Alison M. Strack,Nancy N. Tsou,Richard G. Ball,Junying Wang,Xinchun Tong,Thomas J. Bateman,(unknown),Tung M. Fong,Jeffrey J. Hale	15
6	Prolyl hydroxylase domain-containing protein inhibitors as stabilizers of hypoxia-inducible factor: small molecule-based therapeutics for anemia 2010 ·Expert Opinion on Therapeutic Patents ·Lin Yan,Vincent J. Colandrea,Jeffrey J. Hale	72
7	Pyridopyrimidine based cannabinoid-1 receptor inverse agonists: Synthesis and biological evaluation 2009 ·Bioorganic & Medicinal Chemistry Letters ·John S. Debenham,(unknown),Junying Wang,Xinchun Tong,Julie Lao,Tung M. Fong,Marie‐Therese Schaeffer,Jing Chen Xiao,(unknown),Chun-Pyn Shen,D. Sloan Stribling,Lauren P. Shearman,Alison M. Strack,D. Euan MacIntyre,Jeffrey J. Hale,Thomas F. Walsh	16
8	Synthesis and evaluation of N-[(1S,2S)-3-(4-chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-aminopropanamide as human cannabinoid-1 receptor (CB1R) inverse agonists 2009 ·Bioorganic & Medicinal Chemistry Letters ·Wu Du,James P. Jewell,Linus S. Lin,Vincent J. Colandrea,Jing Chen Xiao,Julie Lao,Chun-Pyn Shen,Thomas J. Bateman,(unknown),Sookhee Ha,Shrenik K. Shah,Tung M. Fong,Jeffrey J. Hale,William K. Hagmann	7
9	Novel 1-(2-aminopyrazin-3-yl)methyl-2-thioureas as potent inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2) 2009 ·Bioorganic & Medicinal Chemistry Letters ·Songnian Lin,(unknown),(unknown),Jeffrey J. Hale,Sander G. Mills,Kevin T. Chapman,James E. Thompson,(unknown),(unknown),Rose M. Cubbon,Edward A. O’Neill,Silvi Luell,Ester Carballo‐Jane,Lihu Yang	18
10	Identification of Leu276 of the S1P1 Receptor and Phe263 of the S1P3 Receptor in Interaction with Receptor Specific Agonists by Molecular Modeling, Site-Directed Mutagenesis, and Affinity Studies 2006 ·Molecular Pharmacology ·Qiaolin Deng,Joseph Clemas,Gary Chrebet,Paul Fischer,Jeffrey J. Hale,Zhen Li,Sander G. Mills,James D. Bergstrom,Suzanne Mandala,Ralph Mosley,Stephen A. Parent	32
11	Highly selective and potent agonists of sphingosine-1-phosphate 1 (S1P1) receptor 2006 ·Bioorganic & Medicinal Chemistry Letters ·Petr Váchal,(unknown),Jeffrey J. Hale,Lin Yan,Sander G. Mills,Gary Chrebet,(unknown),Richard Hajdu,James A. Milligan,Mark Rosenbach,Suzanne Mandala	29
12	Discovery of 3-arylpropionic acids as potent agonists of sphingosine-1-phosphate receptor-1 (S1P1) with high selectivity against all other known S1P receptor subtypes 2006 ·Bioorganic & Medicinal Chemistry Letters ·Lin Yan,(unknown),George Doherty,(unknown),Jeffrey J. Hale,Sander G. Mills,Richard Hajdu,Carol Keohane,Mark Rosenbach,James A. Milligan,Gan-Ju Shei,Gary Chrebet,James D. Bergstrom,Deborah Card,Elizabeth J. Quackenbush,(unknown),Suzanne Mandala	15
13	Potent S1P receptor agonists replicate the pharmacologic actions of the novel immune modulator FTY720 2004 ·Bioorganic & Medicinal Chemistry Letters ·Jeffrey J. Hale,William Neway,Sander G. Mills,Richard Hajdu,Carol Keohane,Mark Rosenbach,James A. Milligan,Gan-Ju Shei,Gary Chrebet,James D. Bergstrom,Deborah Card,Gloria C. Koo,Sam L. Koprak,Jesse J. Jackson,Hugh Rosen,Suzanne Mandala	64
14	Synthesis, stereochemical determination and biochemical characterization of the enantiomeric phosphate esters of the novel immunosuppressive agent FTY720 2004 ·Bioorganic & Medicinal Chemistry ·Jeffrey J. Hale,Lin Yan,William Neway,Richard Hajdu,James D. Bergstrom,James A. Milligan,Gan-Ju Shei,Gary Chrebet,Rosemary Thornton,Deborah Card,Mark Rosenbach,(unknown),Suzanne Mandala	39
15	Selecting against S1P3 enhances the acute cardiovascular tolerability of 3-(N-benzyl)aminopropylphosphonic acid S1P receptor agonists 2004 ·Bioorganic & Medicinal Chemistry Letters ·Jeffrey J. Hale,George Doherty,(unknown),Sander G. Mills,Richard Hajdu,Carol Keohane,Mark Rosenbach,James A. Milligan,Gan-Ju Shei,Gary Chrebet,James D. Bergstrom,Deborah Card,Michael J. Forrest,(unknown),Sarah J. West,Huijuan Xie,Naomi Nomura,Hugh Rosen,Suzanne Mandala	39
16	Sphingosine 1-phosphate receptor agonists attenuate relapsing–remitting experimental autoimmune encephalitis in SJL mice 2004 ·Journal of Neuroimmunology ·Michael Webb,Chui‐Se Tham,Fen‐Fen Lin,Karen Lariosa‐Willingham,Naichen Yu,Jeffrey J. Hale,Suzanne Mandala,Jerold Chun,Tadimeti S. Rao	194
17	Characterization of the binding and activity of a high affinity, pseudoirreversible morpholino tachykinin NK1 receptor antagonist 1997 ·European Journal of Pharmacology ·Margaret A. Cascieri,Elżbieta Ber,Tung M. Fong,Jeffrey J. Hale,(unknown),Lin‐Lin Shiao,Sander G. Mills,Malcolm MacCoss,Sharon Sadowski,Michael R. Tota,Catherine D. Strader	8
18	In vitro and in vivo predictors of the anti-emetic activity of tachykinin NK1 receptor antagonists 1997 ·European Journal of Pharmacology ·N.M.J. Rupniak,F.D. Tattersall,Angela Williams,Wayne Rycroft,Emma Carlson,Margaret A. Cascieri,Sharon Sadowski,Elżbieta Ber,Jeffrey J. Hale,Sander G. Mills,Malcolm MacCoss,Eileen M. Seward,Ian T. Huscroft,Simon N. Owen,Christopher J. Swain,R.G. Hill,Richard Hargreaves	88
19	Mechanism of inhibition of human leukocyte elastase by monocyclic .beta.-lactams 1993 ·Biochemistry ·Renee M. Chabin,(unknown),Philip A. Gale,Alan L. Maycock,(unknown),Conrad P. Dorn,Paul E. Finke,(unknown),Jeffrey J. Hale	19
20	Orally active .beta.-lactam inhibitors of human leukocyte elastase-1. Activity of 3,3-diethyl-2-azetidinones 1992 ·Journal of Medicinal Chemistry ·S. K. Shah,Conrad P. Dorn,(unknown),Jeffrey J. Hale,(unknown),(unknown),Gilbert O. Chandler,(unknown),Bonnie M. Ashe	63

About Jeffrey J. Hale

Jeffrey J. Hale is a scholar working on Cellular and Molecular Neuroscience, Virology and Molecular Biology, having authored 52 papers that have together received 3.0k indexed citations. Recurring topics across this work include Sphingolipid Metabolism and Signaling (15 papers), Receptor Mechanisms and Signaling (10 papers) and Neuropeptides and Animal Physiology (8 papers). The work is most often cited by research in Molecular Biology (2.0k citations), Immunology (563 citations) and Organic Chemistry (650 citations). Jeffrey J. Hale has collaborated with scholars based in United States, Netherlands and India. Frequent co-authors include Suzanne Mandala, James A. Milligan, Mark Rosenbach, James D. Bergstrom, Richard Hajdu, Gan-Ju Shei, Deborah Card, Hugh Rosen, Christopher L. Lynch and Rosemary Thornton. Their work appears in journals such as Science, Proceedings of the National Academy of Sciences and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact