Lihu Yang

2.2k citations

39 papers · 1.1k · h-index 19

Impact in

Endocrine and Autonomic Systems top 5%
- Regulation of Appetite and Obesity
Organic Chemistry top 5%
- Multicomponent Synthesis of Heterocycles
- Synthesis and biological activity

Papers in

Molecular Biology 20
- Chemical Synthesis and Analysis 11
- Receptor Mechanisms and Signaling 5
Oncology 13
- Chemokine receptors and signaling 12
- Cytokine Signaling Pathways and Interactions 5

Co-authors: Songnian Lin (4 shared papers)Sander G. Mills (14 shared papers)Arthur A. Patchett (9 shared papers)Alexander Pasternak (10 shared papers)Pasquale P. Vicario (10 shared papers)Klaus D. Schleim (6 shared papers)Changyou Zhou (8 shared papers)Carina P. Tan (3 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (17 papers)Tetrahedron Letters (9 papers)Journal of Medicinal Chemistry (4 papers)Geographical Research (2 papers)ACS Medicinal Chemistry Letters (1 paper)
Partner nations: United States Switzerland Poland

In The Last Decade

Lihu Yang

39 papers receiving 1.1k citations

Peers

Countries citing papers authored by Lihu Yang

Since Specialization

Citations

This map shows the geographic impact of Lihu Yang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lihu Yang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lihu Yang more than expected).

Fields of papers citing papers by Lihu Yang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lihu Yang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lihu Yang. The network helps show where Lihu Yang may publish in the future.

Co-authors

The 25 scholars most cited alongside Lihu Yang, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lihu Yang Line = papers co-authored together Lihu Yang links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 39 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	A simple and efficient procedure for the synthesis of benzimidazoles using air as the oxidant Tetrahedron Letters ·Songnian Lin, Lihu Yang	2005	192
2	Selective Small-Molecule Agonists of G Protein–Coupled Receptor 40 Promote Glucose-Dependent Insulin Secretion and Reduce Blood Glucose in Mice Diabetes ·Carina P. Tan, Yue Feng, Yun-Ping Zhou, George J. Eiermann, Aleksandr Petrov, Changyou Zhou, Songnian Lin, Gino Salituro, Peter T. Meinke, Ralph Mosley, Taro E. Akiyama, Monica Einstein, Sanjeev Kumar, Joel P. Berger, Sander G. Mills, Nancy A. Thornberry, Lihu Yang, Andrew D. Howard	2008	133
3	Ligand Activation Domain of Human Orphan Growth Hormone (GH) Secretagogue Receptor (GHS-R) Conserved from Pufferfish to Humans Molecular Endocrinology ·Oksana Palyha, Scott D. Feighner, Carina P. Tan, Karen K. McKee, Donna L. Hreniuk, Ying‐Duo Gao, Klaus D. Schleim, Lihu Yang, Gregori J. Morriello, Ravi P. Nargund, Arthur A. Patchett, Andrew Howard, Roy G. Smith	2000	95
4	Solid phase synthesis of ‘head-to-tail’ cyclic peptides using a sulfonamide ‘safety-catch’ linker: the cleavage by cyclization approach Tetrahedron Letters ·Lihu Yang, Greg Morriello	1999	60
5	Solid phase synthesis of Fmoc N-methyl amino acids: Application of the Fukuyama amine synthesis Tetrahedron Letters ·Lihu Yang, Kuenley Chiu	1997	45
6	Spiro[1H-indene-1,4‘-piperidine] Derivatives As Potent and Selective Non-Peptide Human Somatostatin Receptor Subtype 2 (sst₂) Agonists Journal of Medicinal Chemistry ·Lihu Yang, Liangqin Guo, Alexander Pasternak, Ralph Mosley, Susan P. Rohrer, Elizabeth T. Birzin, F Foor, Kang Cheng, James M. Schaeffer, Arthur A. Patchett	1998	45
7	Pictet-Spengler reaction on solid support Tetrahedron Letters ·Lihu Yang, Liangqin Guo	1996	43
8	Potent 3-spiropiperidine growth hormone secretagogues Bioorganic & Medicinal Chemistry Letters ·Lihu Yang, Greg Morriello, Kristine Prendergast, Kang Cheng, Tom Jacks, Wanda Chan, Klaus D. Schleim, Roy G. Smith, Arthur A. Patchett	1998	39
9	Novel, Orally Bioavailable γ-Aminoamide CC Chemokine Receptor 2 (CCR2) Antagonists Journal of Medicinal Chemistry ·Alexander Pasternak, Dominick Marino, Pasquale P. Vicario, Julia M. Ayala, Margaret A. Cascierri, William H. Parsons, Sander G. Mills, Malcolm MacCoss, Lihu Yang	2006	35
10	4-Amino-2-alkyl-butyramides as small molecule CCR2 antagonists with favorable pharmacokinetic properties Bioorganic & Medicinal Chemistry Letters ·Gabor Butora, Gregori J. Morriello, Shankaran Kothandaraman, Deodialsingh Guiadeen, Alexander Pasternak, William H. Parsons, Malcolm MacCoss, Pasquale P. Vicario, Margaret A. Cascieri, Lihu Yang	2006	30
11	1-[2(R)-(2-Amino-2-methylpropionylamino)-3-(1H-indol-3-yl)propionyl]-3- benzylpiperidine-3(S)-carboxylic Acid Ethyl Ester (L-163,540): A Potent, Orally Bioavailable, and Short-Duration Growth Hormone Secretagogue Journal of Medicinal Chemistry ·Lihu Yang, Greg Morriello, Arthur A. Patchett, Kwan Leung, Tom Jacks, Kang Cheng, Klaus D. Schleim, William P. Feeney, Wanda Chan, Shuet‐Hing Lee Chiu, Roy G. Smith	1998	28
12	3-Amino-1-alkyl-cyclopentane carboxamides as small molecule antagonists of the human and murine CC chemokine receptor 2 Bioorganic & Medicinal Chemistry Letters ·Gabor Butora, Richard Jiao, William H. Parsons, Pasquale P. Vicario, Hongjian Jin, Julia M. Ayala, Margaret A. Cascieri, Lihu Yang	2007	25
13	Discovery of a Potent and Orally Bioavailable CCR2 and CCR5 Dual Antagonist ACS Medicinal Chemistry Letters ·Alexander Pasternak, Stephen D. Goble, Mary Struthers, Pasquale P. Vicario, Julia M. Ayala, Jerry Di Salvo, Ruth Kilburn, Thomas Wısnıewskı, Julie A. DeMartino, Sander G. Mills, Lihu Yang	2009	25
14	Discovery of 3-Piperidinyl-1-cyclopentanecarboxamide as a Novel Scaffold for Highly Potent CC Chemokine Receptor 2 Antagonists Journal of Medicinal Chemistry ·Lihu Yang, Gabor Butora, Richard Jiao, Alex Pasternak, Changyou Zhou, William H. Parsons, Sander G. Mills, Pasquale P. Vicario, Julia M. Ayala, Margaret A. Cascieri, Malcolm MacCoss	2007	24
15	A general method for the preparation of 3-acyl-4-cyano-5-amino-pyrazoles Tetrahedron Letters ·Min Ge, Eric Cline, Lihu Yang	2006	23
16	3-Substituted 3-(4-aryloxyaryl)-propanoic acids as GPR40 agonists Bioorganic & Medicinal Chemistry Letters ·Shawn P. Walsh, Alexandra Severino, Changyou Zhou, Jiafang He, Gui‐Bai Liang, Carina P. Tan, Jin Cao, George J. Eiermann, Ling Xu, Gino Salituro, Andrew D. Howard, Sander G. Mills, Lihu Yang	2011	20
17	Discovery of 3,5-bis(trifluoromethyl)benzyl l-arylglycinamide based potent CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Lihu Yang, Changyou Zhou, Liangqin Guo, Gregori J. Morriello, Gabor Butora, Alexander Pasternak, William H. Parsons, Sander G. Mills, Malcolm MacCoss, Pasquale P. Vicario, Hans J. Zweerink, Julia M. Ayala, Shefali Singla, William A. Hanlon, Margaret A. Cascieri, Marty S. Springer	2006	20
18	Design and syntheses of melanocortin subtype-4 receptor agonists: evolution of the pyridazinone archetype Bioorganic & Medicinal Chemistry Letters ·Feroze Ujjainwalla, Daniel Warner, Thomas F. Walsh, Matthew J. Wyvratt, Changyou Zhou, Lihu Yang, Rubana N. Kalyani, Tanya MacNeil, Lex H.T. Van der Ploeg, Charles Rosenblum, Rui Tang, Aurawan Vongs, David H. Weinberg, Mark T. Goulet	2003	19
19	Antidiabetic Activity of a Highly Potent and Selective Nonpeptide Somatostatin Receptor Subtype-2 Agonist Endocrinology ·Mathias Z. Strowski, Doreen E. Cashen, Elizabeth T. Birzin, Lihu Yang, Vandana Singh, Thomas M. Jacks, Krzysztof W. Nowak, Susan P. Rohrer, Arthur A. Patchett, Roy G. Smith, James M. Schaeffer	2006	19
20	Design, synthesis, and structure–activity relationship of novel CCR2 antagonists Bioorganic & Medicinal Chemistry Letters ·Shankaran Kothandaraman, Karla L. Donnely, Gabor Butora, Richard Jiao, Alexander Pasternak, Gregori J. Morriello, Stephen D. Goble, Changyou Zhou, Sander G. Mills, Malcolm MacCoss, Pasquale P. Vicario, Julia M. Ayala, Julie A. DeMartino, Mary Struthers, Margaret A. Cascieri, Lihu Yang	2008	18

About Lihu Yang

Lihu Yang is a scholar working on Molecular Biology, Oncology, Organic Chemistry, Immunology and Endocrine and Autonomic Systems, having authored 39 papers that have together received 1.1k indexed citations. Recurring topics across this work include Chemokine receptors and signaling (12 papers), Chemical Synthesis and Analysis (11 papers), Regulation of Appetite and Obesity (6 papers), Cytokine Signaling Pathways and Interactions (5 papers), Receptor Mechanisms and Signaling (5 papers), Biochemical Analysis and Sensing Techniques (4 papers), Neuropeptides and Animal Physiology (4 papers) and Synthesis and biological activity (4 papers). The work is most often cited by research in Endocrine and Autonomic Systems (144 citations), Organic Chemistry (449 citations), Endocrinology, Diabetes and Metabolism (174 citations), Molecular Biology (501 citations) and Oncology (182 citations). Lihu Yang has collaborated with scholars based in United States, Switzerland and Poland. Frequent co-authors include Songnian Lin, Sander G. Mills, Arthur A. Patchett, Alexander Pasternak, Pasquale P. Vicario, Klaus D. Schleim, Changyou Zhou, Carina P. Tan, Malcolm MacCoss and Julia M. Ayala. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Tetrahedron Letters, Journal of Medicinal Chemistry, Geographical Research and ACS Medicinal Chemistry Letters.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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