Jean‐Sèbastien Hoffmann

16.0k total citations · 1 hit paper
204 papers, 12.7k citations indexed

About

Jean‐Sèbastien Hoffmann is a scholar working on Molecular Biology, Insect Science and Cellular and Molecular Neuroscience. According to data from OpenAlex, Jean‐Sèbastien Hoffmann has authored 204 papers receiving a total of 12.7k indexed citations (citations by other indexed papers that have themselves been cited), including 114 papers in Molecular Biology, 58 papers in Insect Science and 49 papers in Cellular and Molecular Neuroscience. Recurrent topics in Jean‐Sèbastien Hoffmann's work include DNA Repair Mechanisms (73 papers), Neurobiology and Insect Physiology Research (49 papers) and Antimicrobial Peptides and Activities (37 papers). Jean‐Sèbastien Hoffmann is often cited by papers focused on DNA Repair Mechanisms (73 papers), Neurobiology and Insect Physiology Research (49 papers) and Antimicrobial Peptides and Activities (37 papers). Jean‐Sèbastien Hoffmann collaborates with scholars based in France, United States and Brazil. Jean‐Sèbastien Hoffmann's co-authors include Jean‐Marc Reichhart, Charles Hétru, Marie Lagueux, Philippe Bulet, Christophe Cazaux, Bruno Lemaître, Maurice Porchet, Stéphane Cociancich, Jean‐Luc Dimarcq and Christine Kappler and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Jean‐Sèbastien Hoffmann

204 papers receiving 12.3k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Drosophila host defense: Differential induction of antimicrobial peptide genes after infection by various classes of microorganisms

1997 824 citations Jean‐Sèbastien Hoffmann et al. profile →

Peers

Jean‐Sèbastien Hoffmann

IMMUN

MICRO

CMN

Shunji Natori Japan

Dan Hultmark Sweden

Neal Silverman United States

Philippe Bulet France

Jean‐Marc Reichhart France

Charles Hétru France

Émmanuelle Nicolas United States

Shiroh Iwanaga Japan

Sakol Panyim Thailand

Pierre Nicolas France

Shunji Natori Japan

Jean‐Sèbastien Hoffmann

4.9k ×0.8

3.2k ×0.8

IMMUN

3.1k ×0.7

2.0k ×0.7

MICRO

1.7k ×0.6

CMN

Citations per year, relative to Jean‐Sèbastien Hoffmann Jean‐Sèbastien Hoffmann (= 1×) peers Shunji Natori

Countries citing papers authored by Jean‐Sèbastien Hoffmann

Since Specialization

Citations

This map shows the geographic impact of Jean‐Sèbastien Hoffmann's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean‐Sèbastien Hoffmann with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean‐Sèbastien Hoffmann more than expected).

Fields of papers citing papers by Jean‐Sèbastien Hoffmann

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean‐Sèbastien Hoffmann. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean‐Sèbastien Hoffmann. The network helps show where Jean‐Sèbastien Hoffmann may publish in the future.

Co-authorship network of co-authors of Jean‐Sèbastien Hoffmann

This figure shows the co-authorship network connecting the top 25 collaborators of Jean‐Sèbastien Hoffmann. A scholar is included among the top collaborators of Jean‐Sèbastien Hoffmann based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean‐Sèbastien Hoffmann. Jean‐Sèbastien Hoffmann is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Parra, Genı́s, Frédéric Chibon, Fréderic Escudié, et al.. (2023). The hereditary N363K POLE exonuclease mutant extends PPAP tumor spectrum to glioblastomas by causing DNA damage and aneuploidy in addition to increased mismatch mutagenicity. NAR Cancer. 5(2). zcad011–zcad011. 2 indexed citations

Guecheva, Temenouga Nikolova, et al.. (2021). Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer. Cancers. 13(13). 3130–3130. 17 indexed citations

Bournique, Elodie, Chrystelle Maric, Laure Guitton-Sert, et al.. (2021). Low Replicative Stress Triggers Cell-Type Specific Inheritable Advanced Replication Timing. International Journal of Molecular Sciences. 22(9). 4959–4959. 3 indexed citations

Galli, Silvia, Anna Garbelli, Silvia Bione, et al.. (2021). A Role for Human DNA Polymerase λ in Alternative Lengthening of Telomeres. International Journal of Molecular Sciences. 22(5). 2365–2365. 3 indexed citations

Hoffmann, Jean‐Sèbastien. (2021). The Heritability of Replication Problems. Cells. 10(6). 1464–1464. 1 indexed citations

Franchet, Camille, Jean‐Sèbastien Hoffmann, & Florence Dalenc. (2021). Recent Advances in Enhancing the Therapeutic Index of PARP Inhibitors in Breast Cancer. Cancers. 13(16). 4132–4132. 6 indexed citations

Maiorano, Domenico, et al.. (2021). Translesion Synthesis or Repair by Specialized DNA Polymerases Limits Excessive Genomic Instability upon Replication Stress. International Journal of Molecular Sciences. 22(8). 3924–3924. 27 indexed citations

Hoffmann, Jean‐Sèbastien, et al.. (2021). A Catalytically Independent Function of Human DNA Polymerase Kappa Controls the Stability and Abundance of Checkpoint Kinase 1. Molecular and Cellular Biology. 41(11). e0009021–e0009021. 5 indexed citations

Li, Jian, Josephine Mun Yee Ko, Wei Dai, et al.. (2021). Depletion of DNA Polymerase Theta Inhibits Tumor Growth and Promotes Genome Instability through the cGAS-STING-ISG Pathway in Esophageal Squamous Cell Carcinoma. Cancers. 13(13). 3204–3204. 20 indexed citations

10.

Chavarie, Louise, Jean‐Sèbastien Hoffmann, Andrew M. Muir, et al.. (2020). Dietary versus nondietary fatty acid profiles of lake trout ecotypes from Lake Superior and Great Bear Lake: Are fish really what they eat?. Canadian Journal of Fisheries and Aquatic Sciences. 77(7). 1209–1220. 7 indexed citations

11.

Mouchel, Pierre‐Luc, Nizar Serhan, Rémy Betous, et al.. (2020). Dendrogenin A Enhances Anti-Leukemic Effect of Anthracycline in Acute Myeloid Leukemia. Cancers. 12(10). 2933–2933. 10 indexed citations

12.

Bertolin, Agustina P., Jean‐Sèbastien Hoffmann, & Vanesa Gottifredi. (2020). Under-Replicated DNA: The Byproduct of Large Genomes?. Cancers. 12(10). 2764–2764. 19 indexed citations

13.

Besteiro, Marina A. González, Rémy Betous, Marie‐Jeanne Pillaire, et al.. (2019). Chk1 loss creates replication barriers that compromise cell survival independently of excess origin firing. The EMBO Journal. 38(16). e101284–e101284. 15 indexed citations

14.

Bergoglio, Valérie, Yea‐Lih Lin, Marie‐Jeanne Pillaire, et al.. (2019). Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner. Nature Communications. 10(1). 910–910. 96 indexed citations

15.

Muller, David C., Théo Goullet de Rugy, Rémi Samain, et al.. (2019). eIF4A inhibition circumvents uncontrolled DNA replication mediated by 4E-BP1 loss in pancreatic cancer. JCI Insight. 4(21). 25 indexed citations

16.

Franchet, Camille & Jean‐Sèbastien Hoffmann. (2019). When RAD52 Allows Mitosis to Accept Unscheduled DNA Synthesis. Cancers. 12(1). 26–26. 21 indexed citations

17.

Betous, Rémy, Théo Goullet de Rugy, Alessandra Luíza Pelegrini, et al.. (2018). DNA replication stress triggers rapid DNA replication fork breakage by Artemis and XPF. PLoS Genetics. 14(7). e1007541–e1007541. 24 indexed citations

18.

Rugy, Théo Goullet de, Mikhail Bashkurov, Alessandro Datti, et al.. (2016). Excess Polθ functions in response to replicative stress in homologous recombination-proficient cancer cells. Biology Open. 5(10). 1485–1492. 26 indexed citations

19.

Canitrot, Yvan, Guy Laurent, Catherine Astarie‐Dequeker, et al.. (2006). Enhanced expression and activity of DNA polymerase beta in chronic myelogenous leukemia.. PubMed. 26(1B). 523–5. 23 indexed citations

20.

Leopoldino, Andréia Machado, Valérie Bergoglio, Jiyang O‐Wang, et al.. (2005). Up-regulation of the error-prone DNA polymerase {kappa} promotes pleiotropic genetic alterations and tumorigenesis.. PubMed. 65(1). 325–30. 81 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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