Jean Sévigny

15.2k total citations · 2 hit papers
291 papers, 12.3k citations indexed

About

Jean Sévigny is a scholar working on Physiology, Molecular Biology and Speech and Hearing. According to data from OpenAlex, Jean Sévigny has authored 291 papers receiving a total of 12.3k indexed citations (citations by other indexed papers that have themselves been cited), including 235 papers in Physiology, 79 papers in Molecular Biology and 46 papers in Speech and Hearing. Recurrent topics in Jean Sévigny's work include Adenosine and Purinergic Signaling (235 papers), Adolescent and Pediatric Healthcare (46 papers) and Biochemical and Molecular Research (41 papers). Jean Sévigny is often cited by papers focused on Adenosine and Purinergic Signaling (235 papers), Adolescent and Pediatric Healthcare (46 papers) and Biochemical and Molecular Research (41 papers). Jean Sévigny collaborates with scholars based in Canada, United States and Pakistan. Jean Sévigny's co-authors include Simon C. Robson, Herbert Zimmermann, Joanna Lecka, Sébastien A. Lévesque, Élise G. Lavoie, Filip Kukulski, Keiichi Enjyoji, Norbert Braun, Eva Csizmadia and Julie Pelletier and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Circulation.

In The Last Decade

Jean Sévigny

286 papers receiving 12.1k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance

2006 748 citations Simon C. Robson, Jean Sévigny et al. Purinergic Signalling profile →
Identification and Characterization of CD39/Vascular ATP Diphosphohydrolase

1996 488 citations Jean Sévigny, Simon C. Robson et al. profile →

Peers

Countries citing papers authored by Jean Sévigny

Since Specialization

Citations

This map shows the geographic impact of Jean Sévigny's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jean Sévigny with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jean Sévigny more than expected).

Fields of papers citing papers by Jean Sévigny

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jean Sévigny. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jean Sévigny. The network helps show where Jean Sévigny may publish in the future.

Co-authorship network of co-authors of Jean Sévigny

This figure shows the co-authorship network connecting the top 25 collaborators of Jean Sévigny. A scholar is included among the top collaborators of Jean Sévigny based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jean Sévigny. Jean Sévigny is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pursing Quinoline-8-Sulfonamide derivatives for the identification of potent NPPs inhibitors: In silico molecular docking, molecular dynamics simulations and density field theory (DFT) studies 2025 ·Results in Chemistry ·Jamshed Iqbal, (unknown), Mariya al‐Rashida, Abdul Hameed, Tayyaba Iftikhar, Julie Pelletier, Jean Sévigny, Salman Alrokayan, (unknown), Khurshid Ayub, Tajamul Hussain	0
2	P2Y2 Receptor Signaling in Health and Disease 2025 ·International Journal of Molecular Sciences ·(unknown), Jean Sévigny	0
3	Synthesis, Characterization, Interactions, and Immunomodulatory Function of Ectonucleotidase CD39/CD73 Inhibitor 8-Butylthioadenosine 5′-Monophosphate 2025 ·ACS Pharmacology & Translational Science ·(unknown), (unknown), (unknown), Laura Schäkel, Riekje Winzer, (unknown), (unknown), (unknown), Julie Pelletier, Jean Sévigny, Julian Schulze zur Wiesch, (unknown), Eva Tolosa, Vigneshwaran Namasivayam, Norbert Sträter, Christa E. Müller	1
4	Synthesis of 1,3,4-oxadiazole derivatives via transition metal catalyzed cross-coupling and their biological evaluation as selective inhibitors of Ecto-nucleoside triphosphate diphosphohydrolase (NTPDase)-2, -3 and -8 inhibitors 2025 ·Journal of Molecular Structure ·(unknown), Saif Ullah, (unknown), (unknown), Farman Ullah, Imtiaz Khan, Julie Pelletier, (unknown), (unknown), Jean Sévigny, Jamshed Iqbal, Abbas Hassan	1
5	Synthesis, in vitro, and in silico studies of morpholine-based thiosemicarbazones as ectonucleotide pyrophosphatase/phosphodiesterase-1 and -3 inhibitors 2024 ·International Journal of Biological Macromolecules ·(unknown), Julie Pelletier, Jean Sévigny, (unknown), Ajmal Khan, Ahmed Al‐Harrasi, Attalla F. El‐kott, Parham Taslımı, Sally Negm, Zahid Shafiq, Jamshed Iqbal	6
6	UTP increases wound healing in the self assembled skin substitute (SASS) 2023 ·Journal of Cell Communication and Signaling ·(unknown), Jean Sévigny, Véronique Moulin, Márcia Rosângela Wink	5
7	Synthesis of Thieno[3,2‐d]pyrimidine Derivatives through Sequential S_NAr and Suzuki Reactions as Selective h‐NTPDase Inhibitors 2023 ·ChemMedChem ·Gohar Zaman, (unknown), Muhammad Uzair, (unknown), (unknown), Farman Ullah, (unknown), Jean Sévigny, Jamshed Iqbal, Abbas Hassan	5
8	Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h-NTPDases 2023 ·RSC Advances ·(unknown), (unknown), Julie Pelletier, Jean Sévigny, Jamshed Iqbal, Abbas Hassan	1
9	Exploring chromone sulfonamides and sulfonylhydrazones as highly selective ectonucleotidase inhibitors: Synthesis, biological evaluation and in silico study 2023 ·Bioorganic Chemistry ·(unknown), Muhammad Saeed, (unknown), (unknown), Abdul Hameed, Asnuzilawati Asari, Habsah Mohamad, Julie Pelletier, Jean Sévigny, Jamshed Iqbal, Mariya al‐Rashida	10
10	Identification of thienopyrimidine glycinates as selective inhibitors for h-NTPDases 2022 ·Bioorganic Chemistry ·(unknown), (unknown), (unknown), (unknown), Farman Ullah, (unknown), Julie Pelletier, Jean Sévigny, Jamshed Iqbal, Abbas Hassan	6
11	Highly Potent and Selective Ectonucleoside Triphosphate Diphosphohydrolase (ENTPDase1, 2, 3 and 8) Inhibitors Having 2-substituted-7- trifluoromethyl-thiadiazolopyrimidones Scaffold 2020 ·Medicinal Chemistry ·(unknown), Sumera Zaib, Behzad Jafari, Peter Langer, (unknown), Jean Sévigny, Jamshed Iqbal	3
12	Synthesis and Nucleotide Pyrophosphatase/Phosphodiesterase Inhibition Studies of Carbohydrazides Based on Benzimidazole‐Benzothiazine Skeleton 2020 ·ChemistrySelect ·(unknown), (unknown), Matloob Ahmad, Julie Pelletier, Sana Aslam, Sadia Sultan, Jean Sévigny, Mazhar Iqbal, Jamshed Iqbal	6
13	Investigation of new quinoline derivatives as promising inhibitors of NTPDases: Synthesis, SAR analysis and molecular docking studies 2019 ·Bioorganic Chemistry ·(unknown), (unknown), (unknown), (unknown), Shafiq Ur Rahman, Khalid Mohammed Khan, Aamer Saeed, Sumera Zaib, (unknown), Jean Sévigny, Jamshed Iqbal, Abbas Hassan	20
14	Distinctive inhibition of alkaline phosphatase isozymes by thiazol‐2‐ylidene‐benzamide derivatives: Functional insights into their anticancer role 2018 ·Journal of Cellular Biochemistry ·Syeda Abida Ejaz, Aamer Saeed, Syed Jawad Ali Shah, Abdul Hameed, (unknown), Jean Sévigny, Jamshed Iqbal	2
15	Exploration of carboxy pyrazole derivatives: Synthesis, alkaline phosphatase, nucleotide pyrophosphatase/phosphodiesterase and nucleoside triphosphate diphosphohydrolase inhibition studies with potential anticancer profile 2018 ·European Journal of Medicinal Chemistry ·Pervaiz Ali Channar, (unknown), Syeda Abida Ejaz, Aamer Saeed, Fayaz Ali Larik, (unknown), (unknown), Jean Sévigny, Mauricio F. Erben, Jamshed Iqbal	37
16	Distinct roles of ecto-nucleoside triphosphate diphosphohydrolase-2 (NTPDase2) in liver regeneration and fibrosis 2017 ·Purinergic Signalling ·Linda Feldbrügge, Z. Gordon Jiang, Eva Csizmadia, Shuji Mitsuhashi, Stephanie Tran, Eric U. Yee, Sonja Rothweiler, Kahini A. Vaid, Jean Sévigny, Moritz Schmelzle, Yury Popov, Simon C. Robson	19
17	Purine-Metabolizing Ectoenzymes Control IL-8 Production in Human Colon HT-29 Cells 2014 ·Mediators of Inflammation ·Fariborz Bahrami, Filip Kukulski, Joanna Lecka, Alain Tremblay, Julie Pelletier, Liliana Rockenbach, Jean Sévigny	14
18	Cystic fibrosis remodels the regulation of purinergic signaling by NTPDase1 (CD39) and NTPDase3 2010 ·American Journal of Physiology-Lung Cellular and Molecular Physiology ·Michel Fausther, Julie Pelletier, Carla M. P. Ribeiro, Jean Sévigny, Maryse Picher	24
19	CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease 2009 ·Proceedings of the National Academy of Sciences ·David J. Friedman, Beat Künzli, Yousif I. A-Rahim, Jean Sévigny, Pascal O. Berberat, Keiichi Enjyoji, Eva Csizmadia, Helmut Frieß, Simon C. Robson	230
20	Increased Expression of Extracellular ATP Marker NTPDase 1 in the Optic Nerve of Rats With Experimental Glaucoma 2009 ·Investigative Ophthalmology & Visual Science ·(unknown), Hailong Hu, Alan M. Laties, Jean Sévigny, Claire H. Mitchell	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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