J.E. Leysen

7.5k citations

97 papers · 6.1k indexed · 2 hit papers · h-index 38

Impact in

Cellular and Molecular Neuroscience top 0.2%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
Biological Psychiatry top 2%

Papers in

Cellular and Molecular Neuroscience 67
- Neurotransmitter Receptor Influence on Behavior 44
- Neuroscience and Neuropharmacology Research 28
- Neuropeptides and Animal Physiology 22
Molecular Biology 61
- Receptor Mechanisms and Signaling 49
- Pharmacological Receptor Mechanisms and Effects 8
- Nicotinic Acetylcholine Receptors Study 6
- Chemical Synthesis and Analysis 5

Co-authors: W Gommeren Pierre M. Laduron Alain Schotte Paul A. J. Janssen Paul Van Gompel Walter Luyten F. Awouters P.F.M. Janssen
Journals: Life Sciences (9 papers)Molecular Pharmacology (8 papers)Journal of Pharmacology and Experimental Therapeutics (5 papers)Biochemical Pharmacology (5 papers)European Journal of Pharmacology (4 papers)
Partner nations: Belgium Netherlands United Kingdom

In The Last Decade

J.E. Leysen

95 papers receiving 5.8k citations

Hit Papers

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Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding 1996 · 971 citations

Peers

Countries citing papers authored by J.E. Leysen

Since Specialization

Citations

This map shows the geographic impact of J.E. Leysen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J.E. Leysen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J.E. Leysen more than expected).

Fields of papers citing papers by J.E. Leysen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J.E. Leysen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J.E. Leysen. The network helps show where J.E. Leysen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside J.E. Leysen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J.E. Leysen Line = papers co-authored together J.E. Leysen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Synthesis and biodistribution of [11C]R116301, a promising PET ligand for central NK1 receptors Bioorganic & Medicinal Chemistry ·Liang Xiao, Caballo Reservoir, Frans Janssens, Mirek Jurzak, Xavier Langlois, T. Varbanova, Minjeong Jang, Albert D. Windhorst, J.E. Leysen, Jacobus D. M. Herscheid	2005	10
2	Detailed localization of regulator of G protein signaling 2 messenger ribonucleic acid and protein in the rat brain Neuroscience ·Jean‐Marc Taymans, Cindy Wintmolders, Paula te Riele, Mirek Jurzak, Henk J. Groenewegen, J.E. Leysen, Xavier Langlois	2002	29
3	Pharmacological Profile of (2 R-trans)-4-[1-[3,5-bis(Trifluoromethyl)benzoyl]-2-(phenylmethyl)-4-piperidinyl]-N-(2,6-dimethylphenyl)-1-acetamide (S)-Hydroxybutanedioate (R116301), an Orally and Centrally Active Neurokinin-1 Receptor Antagonist Journal of Pharmacology and Experimental Therapeutics ·Anton A. H. P. Megens, D. Ashton, Nelson Kwok Wang Hung, Colton Hansen, نادية سعيد عيشور, Mulele Simasiku, Quimi, Robledo Roldán, Lieve Heylen, J.E. Leysen, Mirek Jurzak, Frans Janssens	2002	20
4	Mapping of serotonin 5-HT4 receptor mRNA and ligand binding sites in the post-mortem human brain Synapse ·Pascal Bonaventure, H�kan Hall, W Gommeren, Patrick Cras, Xavier Langlois, Mirek Jurzak, J.E. Leysen	2000	76
5	Comparison of the Ligand Binding and Signaling Properties of Human Dopamine D2 and D3 Receptors in Chinese Hamster Ovary Cells Journal of Pharmacology and Experimental Therapeutics ·Jurgen F.M. Vanhauwe, Norbert Fraeyman, Д О Сєріков, Walter Luyten, J.E. Leysen	1999	45
6	Humanization of Mouse 5-Hydroxytryptamine_1BReceptor Gene by Homologous Recombination: In Vitro and In Vivo Characterization Molecular Pharmacology ·Pascal Bonaventure, Lieve Umans, Margot H.M. Bakker, Patrick Cras, Xavier Langlois, Walter Luyten, Anton A. H. P. Megens, Lutgarde Serneels, F. Van Leuven, J.E. Leysen	1999	9
7	Co-localization of 5-HT1B- and 5-HT1D receptor mRNA in serotonergic cell bodies in guinea pig dorsal raphé nucleus: a double labeling in situ hybridization histochemistry study Neuroscience Letters ·Pascal Bonaventure, Xavier Langlois, J.E. Leysen	1998	29
8	The tachykinin NK1 receptor antagonist, RP67580, inhibits the bradykinin-induced rise in intracellular Ca2+ concentration in bovine pulmonary artery endothelial cells European Journal of Pharmacology ·Lilian Nafuna, R. A. Neale, Andries S. Koster, Jaap Wilting, J.E. Leysen, D. van Heuven-Nolsen, Frans P. Nijkamp	1998	2
9	Endogenous dopamine limits the binding of antipsychotic drugs to D3 receptors in the rat brain: a quantitative autoradiographic study The Histochemical Journal ·Alain Schotte, P.F.M. Janssen, Pascal Bonaventure, J.E. Leysen	1996	38
10	Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding Psychopharmacology ·Alain Schotte, Paul Janssen, W Gommeren, Walter Luyten, Paul Van Gompel, Anne Lesage, M.C. Cornel, J.E. Leysen Hit paper breakdown →	1996	971
11	Survey on the pharmacodynamics of the new antipsychotic risperidone Psychopharmacology ·Anton A. H. P. Megens, F. Awouters, Alain Schotte, T. Meert, Christine Dugovic, C. J. E. Niemegeers, J.E. Leysen	1994	175
12	Occupancy of central neurotransmitter receptors by risperidone, clozapine and haloperidol, measured ex vivo by quantitative autoradiography Brain Research ·Alain Schotte, P.F.M. Janssen, Anton A. H. P. Megens, J.E. Leysen	1993	190
13	Synthesis and biological activities of ψ(CH₂NH) pseudopeptide analogues of the C‐terminal hexapeptide of neurotensin International journal of peptide & protein research ·Liz Low, Dirk Tourwé, G. Van Binst, Wanling Wei, J.E. Leysen	1993	15
14	Genomic Cloning, Heterologous Expression and Pharmacological Characterization of a Human Histamine H1 Receptor Biochemical and Biophysical Research Communications ·R. Andrés, W Gommeren, Henri Moereels, Giulia Castellani, H. B. Weaver, J.E. Leysen, Walter Luyten	1993	113
15	Chronic 5-HT2 receptor antagonist treatment alters 5-HT1A autoregulatory control of 5-HT release in rat brain in vivo Journal of Neuroscience Methods ·Emma J. Kidd, J.E. Leysen, C.A. Marsden	1990	7
16	Ca2+-mediated neuronal death in rat brain neuronal cultures by veratridine: protection by flunarizine. Molecular Pharmacology ·Petrus J. Pauwels, Kozaburo Nakae, J.E. Leysen, P A Janssen	1989	71
17	The receptor binding profile of the new antihypertensive agent nebivolol and its stereoisomers compared with various beta-adrenergic blockers. Molecular Pharmacology ·Petrus J. Pauwels, W Gommeren, Guy Van Lommen, Paul A. J. Janssen, J.E. Leysen	1988	92
18	Further analysis of the neuropharmacological profile of 9-amino-1,2,3,4-tetrahydroacridine (THA), an alleged drug for the treatment of Alzheimer's disease Life Sciences ·Benjamin Drukarch, J.E. Leysen, J.C. Stoof	1988	76
19	Effects of lesions on 3H-apomorphine and 3H-spiperone stereospecific binding sites in subcellular fractions of rat striatum Neurochemistry International ·J.E. Leysen	1981	7
20	Apomorphine: Chemistry, Pharmacology, Biochemistry International review of neurobiology ·Françis C. Colpaert, Willem F. M. Van Bever, J.E. Leysen	1976	110

About J.E. Leysen

J.E. Leysen is a scholar working on Cellular and Molecular Neuroscience, Molecular Biology, Biochemistry, Psychiatry and Mental health and Organic Chemistry, having authored 97 papers that have together received 6.1k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (49 papers), Neurotransmitter Receptor Influence on Behavior (44 papers), Neuroscience and Neuropharmacology Research (28 papers), Neuropeptides and Animal Physiology (22 papers), Pharmacological Receptor Mechanisms and Effects (8 papers), Nicotinic Acetylcholine Receptors Study (6 papers), Chemical Synthesis and Analysis (5 papers) and Radiopharmaceutical Chemistry and Applications (4 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (3.6k citations), Biological Psychiatry (254 citations), Psychiatry and Mental health (1.3k citations), Molecular Biology (2.8k citations) and Behavioral Neuroscience (139 citations). J.E. Leysen has collaborated with scholars based in Belgium, Netherlands and United Kingdom. Frequent co-authors include W Gommeren, Pierre M. Laduron, Alain Schotte, Paul A. J. Janssen, Paul Van Gompel, Walter Luyten, F. Awouters, P.F.M. Janssen, Anne Lesage and Ludo Kennis. Their work appears in journals such as Life Sciences, Molecular Pharmacology, Journal of Pharmacology and Experimental Therapeutics, Biochemical Pharmacology and European Journal of Pharmacology.

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