Jason O’Neill

2.5k citations

29 papers · 1.9k indexed · h-index 21

Impact in

Molecular Biology top 5%
- Developmental Biology and Gene Regulation
- Cell death mechanisms and regulation
- RNA Interference and Gene Delivery
- Protein Structure and Dynamics
- Glycosylation and Glycoproteins Research
- Enzyme function and inhibition
Biotechnology top 5%

Papers in

Co-authors: Ethan Bier Kam Y. J. Zhang David M. Hockenbery Michael K. Manion V. François Mark J. Solloway Arnd Sturm Maarten J. Chrispeels
Journals: Protein Science (2 papers)Journal of Biological Chemistry (2 papers)Molecular Pharmaceutics (1 paper)PLANT PHYSIOLOGY (1 paper)Current Medicinal Chemistry (1 paper)
Partner nations: United States Canada United Kingdom

In The Last Decade

Jason O’Neill

29 papers receiving 1.9k citations

Peers

Countries citing papers authored by Jason O’Neill

Since Specialization

Citations

This map shows the geographic impact of Jason O’Neill's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jason O’Neill with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jason O’Neill more than expected).

Fields of papers citing papers by Jason O’Neill

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jason O’Neill. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jason O’Neill. The network helps show where Jason O’Neill may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Jason O’Neill, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Jason O’Neill Line = papers co-authored together Jason O’Neill links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Characterization of the interactions of potent allosteric inhibitors with glutaminase C, a key enzyme in cancer cell glutamine metabolism Journal of Biological Chemistry ·Qingqiu Huang, Clint A. Stalnecker, Chengliang Zhang, Lee McDermott, 王春芳, Jason O’Neill, Wannaporn Nilpanit, Richard A. Cerione, William P. Katt	2018	68
2	Design and evaluation of novel glutaminase inhibitors Bioorganic & Medicinal Chemistry ·Lee McDermott, 王春芳, Lawrence A. Vernetti, G. Riera, Jingran Sun, Melissa L. Boby, Tianyi Yang, Gellrich Nils-Claudius, Jason O’Neill, Liwei Wang, Dylan J. Drakes, William P. Katt, Qingqiu Huang, Richard A. Cerione	2016	47
3	Development of a scintillation proximity binding assay for high-throughput screening of hematopoietic prostaglandin D2 synthase Analytical Biochemistry ·Ipik Ropikoh, Bobbie Thomasson, Chidambaram Ramachandran, Jason O’Neill, Klaus Michelsen, Mei-Chu Lo	2016	4
4	SLC46A3 Is Required to Transport Catabolites of Noncleavable Antibody Maytansine Conjugates from the Lysosome to the Cytoplasm Cancer Research ·Kevin J. Hamblett, Allison P. Jacob, Jesse L. Gurgel, Mark Tometsko, Brooke M. Rock, Sonal Patel, Robert R. Milburn, Sophia Siu, Seamus P. Ragan, Dan A. Rock, Christopher J. Borths, Jason O’Neill, Wesley Chang, Margaret F. Weidner, Matthew M. Bio, Kim Quon, William C. Fanslow	2015	90
5	Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity Cancer Cell ·Jonathan D. Graves, Jennifer J. Kordich, Tzu-Hsuan Huang, Julia Piasecki, Tammy L. Bush, Timothy J. Sullivan, Ian N. Foltz, Wesley Chang, Ben Rong Sun, Thu Thi Dang, Jason O’Neill, O'Toole Laura J., Xiaoning Zhao, Daniel Branstetter, John M. Rossi, Alexander Long, Xin Huang, Pamela M. Holland	2014	137
6	Fusion Partners as a Tool for the Expression of Difficult Proteins in Mammalian Cells Current Pharmaceutical Biotechnology ·Jue Zhang, Jane Carter, Sophia Siu, Jason O’Neill, Kgalema Motlanthe, John Delaney, Christopher Mehlin	2010	16
7	Fusion partners can increase the expression of recombinant interleukins via transient transfection in 2936E cells Protein Science ·Jane Carter, Jue Zhang, Z Surmacz, Haruki Hasegawa, Janet Cheng, Juan Carlos Martín Baranda, Jason O’Neill, Martin F. Wolfson, Sophia Siu, Alicia Bond, David Meininger, Helen Kim, John Delaney, Christopher Mehlin	2009	22
8	BCL-XL Dimerization by Three-dimensional Domain Swapping Journal of Molecular Biology ·Jason O’Neill, Michael K. Manion, Brendan C. Maguire, David M. Hockenbery	2005	80
9	Promises and challenges of targeting Bcl-2 anti-apoptotic proteins for cancer therapy Biochimica et Biophysica Acta (BBA) - Reviews on Cancer ·Jason O’Neill, Michael K. Manion, Esma Eröz, David M. Hockenbery	2004	72
10	Mcl-1 is required for Akata6 B-lymphoma cell survival and is converted to a cell death molecule by efficient caspase-mediated cleavage Oncogene ·Jorg Michels, Jason O’Neill, Paul Coehn, Pratik Desmukh, Fay Habens, Matthew Brimmell, Kam Y. J. Zhang, Ruth W. Craig, Eric G. Marcusson, Peter Johnson, Graham Packham	2004	122
11	Bcl-XL Mutations Suppress Cellular Sensitivity to Antimycin A Journal of Biological Chemistry ·Michael K. Manion, Jason O’Neill, سهیلا خسروابادی, Kristine M. Kim, Kam Y. J. Zhang, David M. Hockenbery	2004	65
12	Bcl-2-Related Proteins as Drug Targets Current Medicinal Chemistry ·Jason O’Neill, David M. Hockenbery	2003	13
13	Mitochondria and apoptosis: New therapeutic targets Advances in cancer research ·David M. Hockenbery, Roberl J. Vinci, Jason O’Neill, Michael K. Manion, Deborah E. Banker	2002	46
14	Crystal structure of E. coli β–carbonic anhydrase, an enzyme with an unusual pH–dependent activity Protein Science ·J.D. Cronk, James A. Endrizzi, Michelle R. Cronk, Jason O’Neill, Kam Y. J. Zhang	2001	122
15	Conversion of monomeric protein L to an obligate dimer by computational protein design Proceedings of the National Academy of Sciences ·Brian Kuhlman, Jason O’Neill, David E. Kim, Kam Y. J. Zhang, David Baker	2001	63
16	Single-Site Mutations Induce 3D Domain Swapping in the B1 Domain of Protein L from Peptostreptococcus magnus Structure ·Jason O’Neill, David E. Kim, Mária Brišová, David Baker, Kam Y. J. Zhang	2001	47
17	Structures of the B1 domain of protein L fromPeptostreptococcus magnuswith a tyrosine to tryptophan substitution Acta Crystallographica Section D Biological Crystallography ·Jason O’Neill, David E. Kim, David Baker, Kam Y. J. Zhang	2001	55
18	Crystallization and preliminary X-ray diffraction studies of mutants of B1 IgG-binding domain of protein L fromPeptostreptococcus magnus Acta Crystallographica Section D Biological Crystallography ·Mária Brišová, Jason O’Neill, David E. Kim, David Baker, Kam Y. J. Zhang	2000	3
19	TheDrosophilaRhomboid Protein Is Concentrated in Patches at the Apical Cell Surface Developmental Biology ·Mark A. Sturtevant, Margaret Roark, Jason O’Neill, Brian Biehs, Nansi Jo Colley, Ethan Bier	1996	47
20	Double-label in situ hybridization using biotin and digoxigenin-tagged RNA probes. PubMed ·Jason O’Neill, Ethan Bier	1994	148

About Jason O’Neill

Jason O’Neill is a scholar working on Discrete Mathematics and Combinatorics, Biotechnology, Molecular Biology, Cancer Research and Immunology, having authored 29 papers that have together received 1.9k indexed citations. Recurring topics across this work include Cell death mechanisms and regulation (5 papers), Monoclonal and Polyclonal Antibodies Research (4 papers), Enzyme Structure and Function (4 papers), Glycosylation and Glycoproteins Research (3 papers), RNA Interference and Gene Delivery (3 papers), Protein Structure and Dynamics (2 papers), Neurobiology and Insect Physiology Research (2 papers) and HER2/EGFR in Cancer Research (2 papers). The work is most often cited by research in Molecular Biology (1.6k citations), Biotechnology (127 citations), Immunology (248 citations), Cell Biology (181 citations) and Cancer Research (159 citations). Jason O’Neill has collaborated with scholars based in United States, Canada and United Kingdom. Frequent co-authors include Ethan Bier, Kam Y. J. Zhang, David M. Hockenbery, Michael K. Manion, V. François, Mark J. Solloway, Arnd Sturm, Maarten J. Chrispeels, Antje von Schaewen and David E. Kim. Their work appears in journals such as Protein Science, Journal of Biological Chemistry, Molecular Pharmaceutics, PLANT PHYSIOLOGY and Current Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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