Jan Karlseder

12.3k total citations · 5 hit papers
67 papers, 9.4k citations indexed

About

Jan Karlseder is a scholar working on Molecular Biology, Physiology and Aging. According to data from OpenAlex, Jan Karlseder has authored 67 papers receiving a total of 9.4k indexed citations (citations by other indexed papers that have themselves been cited), including 56 papers in Molecular Biology, 52 papers in Physiology and 14 papers in Aging. Recurrent topics in Jan Karlseder's work include Telomeres, Telomerase, and Senescence (50 papers), DNA Repair Mechanisms (34 papers) and Genetics, Aging, and Longevity in Model Organisms (14 papers). Jan Karlseder is often cited by papers focused on Telomeres, Telomerase, and Senescence (50 papers), DNA Repair Mechanisms (34 papers) and Genetics, Aging, and Longevity in Model Organisms (14 papers). Jan Karlseder collaborates with scholars based in United States, Austria and Japan. Jan Karlseder's co-authors include Titia de Lange, Roderick J. O’Sullivan, Ramiro E. Verdún, Agata Smogorzewska, Laure Crabbé, Candy Haggblom, Stephen Hardy, Dominique Broccoli, Yumin Dai and Makoto Hayashi and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Jan Karlseder

67 papers receiving 9.3k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

1999 869 citations Jan Karlseder, Dominique Broccoli et al. Science profile →
Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

2009 788 citations Agnel Sfeir, Settapong T Kosiyatrakul et al. profile →
Telomeres: protecting chromosomes against genome instability

2010 743 citations Roderick J. O’Sullivan, Jan Karlseder profile →
Senescence Induced by Altered Telomere State, Not Telomere Loss

2002 627 citations Jan Karlseder, Agata Smogorzewska et al. Science profile →
Autophagic cell death restricts chromosomal instability during replicative crisis

2019 329 citations Joe Nassour, Javier Miralles Fusté et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jan Karlseder United States	42	7.3k	5.6k	1.1k	896	876	67	9.4k
Shawn E. Holt United States	34	5.5k 0.8×	6.1k 1.1×	1.1k 0.9×	440 0.5×	1.1k 1.3×	63	9.4k
Joachim Lingner Switzerland	58	10.3k 1.4×	8.6k 1.5×	1.4k 1.2×	1.5k 1.7×	569 0.6×	101	13.1k
Andrea Bodnár Hungary	25	4.8k 0.7×	4.3k 0.8×	840 0.7×	330 0.4×	708 0.8×	46	7.9k
Sandy Chang United States	46	7.6k 1.0×	4.9k 0.9×	964 0.8×	688 0.8×	3.2k 3.7×	88	11.3k
A. B. Futcher United States	16	5.6k 0.8×	5.7k 1.0×	1.3k 1.1×	903 1.0×	619 0.7×	18	9.3k
Serge Lichtsteiner United States	14	4.2k 0.6×	4.0k 0.7×	774 0.7×	336 0.4×	734 0.8×	14	6.9k
Karen R. Prowse United States	17	5.0k 0.7×	5.4k 1.0×	706 0.6×	392 0.4×	972 1.1×	24	8.5k
Agata Smogorzewska United States	40	12.2k 1.7×	5.4k 1.0×	1.1k 1.0×	1.4k 1.6×	2.6k 3.0×	71	14.7k
Walter D. Funk United States	38	5.4k 0.7×	2.8k 0.5×	404 0.4×	304 0.3×	1.7k 1.9×	66	7.9k
Eros Lazzerini Denchi United States	29	4.7k 0.6×	1.7k 0.3×	271 0.2×	416 0.5×	1.5k 1.7×	45	5.7k

Countries citing papers authored by Jan Karlseder

Since Specialization

Citations

This map shows the geographic impact of Jan Karlseder's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jan Karlseder with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jan Karlseder more than expected).

Fields of papers citing papers by Jan Karlseder

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jan Karlseder. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jan Karlseder. The network helps show where Jan Karlseder may publish in the future.

Co-authorship network of co-authors of Jan Karlseder

This figure shows the co-authorship network connecting the top 25 collaborators of Jan Karlseder. A scholar is included among the top collaborators of Jan Karlseder based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jan Karlseder. Jan Karlseder is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Nassour, Joe & Jan Karlseder. (2025). Telomere Crisis Shapes Cancer Evolution. Cold Spring Harbor Perspectives in Biology. 18(3). a041688–a041688. 1 indexed citations

Schmidt, T., Candy Haggblom, Jeffrey R. Jones, et al.. (2024). High resolution long-read telomere sequencing reveals dynamic mechanisms in aging and cancer. Nature Communications. 15(1). 5149–5149. 29 indexed citations

Nassour, Joe, T. Schmidt, Sara Przetocka, et al.. (2023). Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis. Nature. 614(7949). 767–773. 97 indexed citations

Masamsetti, V. Pragathi, Ronnie Ren Jie Low, Ka Sin Mak, et al.. (2019). Replication stress induces mitotic death through parallel pathways regulated by WAPL and telomere deprotection. Nature Communications. 10(1). 4224–4224. 33 indexed citations

Fusté, Javier Miralles, et al.. (2017). TZAP: A telomere-associated protein involved in telomere length control. Science. 355(6325). 638–641. 119 indexed citations

Lackner, Daniel H., Makoto Hayashi, Anthony J. Cesare, & Jan Karlseder. (2014). A genomics approach identifies senescence‐specific gene expression regulation. Aging Cell. 13(5). 946–950. 39 indexed citations

Oganesian, Liana & Jan Karlseder. (2013). 5′ C-rich telomeric overhangs are an outcome of rapid telomere truncation events. DNA repair. 12(3). 238–245. 22 indexed citations

Lackner, Daniel H., Marcela Raı́ces, Hugo Maruyama, Candy Haggblom, & Jan Karlseder. (2012). Organismal propagation in the absence of a functional telomerase pathway in Caenorhabditis elegans. The EMBO Journal. 31(8). 2024–2033. 23 indexed citations

Flynn, Rachel Litman, Richard C. Centore, Roderick J. O’Sullivan, et al.. (2011). TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA. Nature. 471(7339). 532–536. 264 indexed citations

10.

Oganesian, Liana & Jan Karlseder. (2011). Mammalian 5′ C-Rich Telomeric Overhangs Are a Mark of Recombination-Dependent Telomere Maintenance. Molecular Cell. 42(2). 224–236. 73 indexed citations

11.

Lackner, Daniel H., Daniel Durocher, & Jan Karlseder. (2011). A siRNA-Based Screen for Genes Involved in Chromosome End Protection. PLoS ONE. 6(6). e21407–e21407. 12 indexed citations

12.

Sfeir, Agnel, Settapong T Kosiyatrakul, Dirk Hockemeyer, et al.. (2009). Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication. 138(1). 90–103. 32 indexed citations

13.

Karlseder, Jan & Julia Promisel Cooper. (2007). Of wombats and whales: telomere tales in Madrid. EMBO Reports. 8(6). 542–546. 1 indexed citations

14.

Verdún, Ramiro E., Laure Crabbé, Candy Haggblom, & Jan Karlseder. (2005). Functional Human Telomeres Are Recognized as DNA Damage in G2 of the Cell Cycle. Molecular Cell. 20(4). 551–561. 226 indexed citations

15.

Raı́ces, Marcela, Hugo Maruyama, Andrew Dillin, & Jan Karlseder. (2005). Uncoupling of Longevity and Telomere Length in C. elegans. PLoS Genetics. 1(3). e30–e30. 55 indexed citations

16.

Crabbé, Laure, Ramiro E. Verdún, Candy Haggblom, & Jan Karlseder. (2004). Defective Telomere Lagging Strand Synthesis in Cells Lacking WRN Helicase Activity. Science. 306(5703). 1951–1953. 480 indexed citations

17.

Smogorzewska, Agata, Jan Karlseder, Heidi Holtgreve-Grez, Anna Jauch, & Titia de Lange. (2002). DNA Ligase IV-Dependent NHEJ of Deprotected Mammalian Telomeres in G1 and G2. Current Biology. 12(19). 1635–1644. 310 indexed citations

18.

Karlseder, Jan, Dominique Broccoli, Yumin Dai, Stephen Hardy, & Titia de Lange. (1999). p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2. Science. 283(5406). 1321–1325. 869 indexed citations breakdown →

19.

Orel, Lukas, Manuel Simon, Jan Karlseder, et al.. (1997). α-Melanocyte Stimulating Hormone Downregulates Differentiation-Driven Heat Shock Protein 70 Expression in Keratinocytes. Journal of Investigative Dermatology. 108(4). 401–405. 27 indexed citations

20.

Bartl, Stefan, et al.. (1996). Carboxy-terminal Residues of Mouse Thymidine Kinase are Essential for Rapid Degradation in Quiescent Cells. Journal of Molecular Biology. 259(3). 383–392. 27 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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