James W. Murrough

22.1k total citations · 8 hit papers
170 papers, 13.9k citations indexed

About

James W. Murrough is a scholar working on Pharmacology, Biological Psychiatry and Cognitive Neuroscience. According to data from OpenAlex, James W. Murrough has authored 170 papers receiving a total of 13.9k indexed citations (citations by other indexed papers that have themselves been cited), including 90 papers in Pharmacology, 68 papers in Biological Psychiatry and 46 papers in Cognitive Neuroscience. Recurrent topics in James W. Murrough's work include Treatment of Major Depression (89 papers), Tryptophan and brain disorders (68 papers) and Functional Brain Connectivity Studies (36 papers). James W. Murrough is often cited by papers focused on Treatment of Major Depression (89 papers), Tryptophan and brain disorders (68 papers) and Functional Brain Connectivity Studies (36 papers). James W. Murrough collaborates with scholars based in United States, Australia and United Kingdom. James W. Murrough's co-authors include Dennis S. Charney, Sanjay J. Mathew, Dan V. Iosifescu, Andrew M. Perez, Katherine A. Collins, Scott J. Russo, Ming‐Hu Han, Eric J. Nestler, Marije aan het Rot and Adriana Feder and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and The Lancet.

In The Last Decade

James W. Murrough

167 papers receiving 13.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Antidepressant Efficacy of Ketamine in Treatment-Resistant Major Depression: A Two-Site Randomized Controlled Trial

2013 884 citations James W. Murrough, Dan V. Iosifescu et al. American Journal of Psychiatry profile →
Neurobiology of resilience

2012 800 citations Scott J. Russo, James W. Murrough et al. profile →
Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression

2012 591 citations James W. Murrough, Sanjay J. Mathew et al. profile →
Safety and Efficacy of Repeated-Dose Intravenous Ketamine for Treatment-Resistant Depression

2009 533 citations James W. Murrough, Dennis S. Charney et al. profile →
The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis

2017 476 citations Samuel T. Wilkinson, Elizabeth D. Ballard et al. American Journal of Psychiatry profile →
Relation between resting amygdalar activity and cardiovascular events: a longitudinal and cohort study

2017 420 citations Cheuk Y. Tang, James W. Murrough et al. profile →
Efficacy of Intravenous Ketamine for Treatment of Chronic Posttraumatic Stress Disorder

2014 391 citations Adriana Feder, James W. Murrough et al. profile →
Screening and Management of Depression in Patients With Cardiovascular Disease

2019 216 citations Dennis S. Charney, James W. Murrough et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
James W. Murrough United States	61	6.6k	5.8k	3.0k	2.9k	2.3k	170	13.9k
Sanjay J. Mathew United States	54	6.2k 0.9×	5.3k 0.9×	2.3k 0.8×	3.0k 1.0×	1.9k 0.8×	186	11.3k
David A. Luckenbaugh United States	72	8.2k 1.2×	6.9k 1.2×	3.6k 1.2×	4.7k 1.6×	2.3k 1.0×	159	17.9k
Diane Warden United States	42	8.7k 1.3×	4.0k 0.7×	2.3k 0.8×	1.8k 0.6×	4.4k 1.9×	80	14.9k
Patrick J. McGrath United States	57	8.0k 1.2×	3.5k 0.6×	4.2k 1.4×	2.1k 0.7×	4.3k 1.9×	187	16.6k
Gerard Sanacora United States	72	8.3k 1.2×	9.0k 1.6×	4.3k 1.5×	8.6k 2.9×	1.9k 0.8×	192	21.6k
Todd D. Gould United States	58	3.6k 0.5×	3.8k 0.7×	3.1k 1.0×	4.8k 1.6×	1.2k 0.5×	141	15.6k
Richard C. Shelton United States	57	4.4k 0.7×	2.7k 0.5×	1.8k 0.6×	1.4k 0.5×	3.6k 1.5×	244	13.5k
Andrew A. Nierenberg United States	57	9.5k 1.4×	4.1k 0.7×	2.6k 0.9×	1.8k 0.6×	5.0k 2.2×	117	17.3k
Glenda MacQueen Canada	70	3.3k 0.5×	2.8k 0.5×	4.3k 1.5×	2.7k 0.9×	2.5k 1.1×	270	19.4k
George I. Papakostas United States	56	4.8k 0.7×	2.9k 0.5×	1.5k 0.5×	993 0.3×	2.4k 1.0×	243	10.6k

Countries citing papers authored by James W. Murrough

Since Specialization

Citations

This map shows the geographic impact of James W. Murrough's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James W. Murrough with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James W. Murrough more than expected).

Fields of papers citing papers by James W. Murrough

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James W. Murrough. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James W. Murrough. The network helps show where James W. Murrough may publish in the future.

Co-authorship network of co-authors of James W. Murrough

This figure shows the co-authorship network connecting the top 25 collaborators of James W. Murrough. A scholar is included among the top collaborators of James W. Murrough based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James W. Murrough. James W. Murrough is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Sanacora, Gerard, Brian S. Barnett, Bo Hu, et al.. (2025). Patient preference effects in a randomized comparative effectiveness study of electroconvulsive therapy and ketamine for treatment resistant depression: An ELEKT-D trial secondary analysis. Psychiatry Research. 347. 116411–116411.

Altinay, Murat, Mahendra T. Bhati, Susan K. Conroy, et al.. (2025). Genetics of Response to ECT, TMS, Ketamine and Esketamine. American Journal of Medical Genetics Part B Neuropsychiatric Genetics. 198(7). 88–102. 1 indexed citations

Bachi, Keren, et al.. (2024). Intrinsic and extrinsic control impact motivation and outcome sensitivity: the role of anhedonia, stress, and anxiety. Psychological Medicine. 54(16). 4575–4584. 2 indexed citations

Murrough, James W., et al.. (2023). Brain Features of Treatment-Resistant Depression. Psychiatric Clinics of North America. 46(2). 391–401. 7 indexed citations

Frolinger, Tal, et al.. (2023). The Bioactive Dietary Polyphenol Preparation Alleviates Depression and Anxiety‐Like Behaviors by Modulating the Regional Heterogeneity of Microglia Morphology. Molecular Nutrition & Food Research. 67(21). e2300156–e2300156. 6 indexed citations

Darrow, Sabrina M., Diego A. Pizzagalli, Moria J. Smoski, et al.. (2023). Using latent profile analyses to classify subjects with anhedonia based on reward-related measures obtained in the FAST-MAS study. Journal of Affective Disorders. 339. 584–592. 2 indexed citations

Ranti, Daniel, John W. Rutland, Sarah Rutter, et al.. (2022). Perivascular spaces as a marker of psychological trauma in depression: A 7‐Tesla MRI study. Brain and Behavior. 12(7). e32598–e32598. 13 indexed citations

Kaye‐Kauderer, Halley, George Loo, James W. Murrough, et al.. (2021). Effects of Sleep, Exercise, and Leadership Support on Resilience in Frontline Healthcare Workers During the COVID-19 Pandemic. Journal of Occupational and Environmental Medicine. 64(5). 416–420. 8 indexed citations

Mathé, Aleksander A., et al.. (2020). A Randomized Controlled Trial of Intranasal Neuropeptide Y in Patients With Major Depressive Disorder. The International Journal of Neuropsychopharmacology. 23(12). 783–790. 34 indexed citations

10.

Averill, Lynnette A., et al.. (2020). Chronic stress pathology and ketamine-induced alterations in functional connectivity in major depressive disorder: An abridged review of the clinical evidence. Advances in pharmacology. 89. 163–194. 12 indexed citations

11.

Krystal, Andrew D., Diego A. Pizzagalli, Moria J. Smoski, et al.. (2020). A randomized proof-of-mechanism trial applying the ‘fast-fail’ approach to evaluating κ-opioid antagonism as a treatment for anhedonia. Nature Medicine. 26(5). 760–768. 155 indexed citations

12.

Citrome, Leslie, Bradley N. Gaynes, Joseph F. Goldberg, Terence A. Ketter, & James W. Murrough. (2019). New Mechanisms, New Opportunities. The Journal of Clinical Psychiatry. 80(5). 1 indexed citations

13.

Kiraly, Drew D., Sarah R. Horn, Nicholas T. Van Dam, et al.. (2017). Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome. Translational Psychiatry. 7(3). e1065–e1065. 149 indexed citations

14.

Wilkinson, Samuel T., Elizabeth D. Ballard, Michael H. Bloch, et al.. (2017). The Effect of a Single Dose of Intravenous Ketamine on Suicidal Ideation: A Systematic Review and Individual Participant Data Meta-Analysis. American Journal of Psychiatry. 175(2). 150–158. 476 indexed citations breakdown →

15.

Murrough, James W., Chadi G. Abdallah, & Sanjay J. Mathew. (2017). Targeting glutamate signalling in depression: progress and prospects. Nature Reviews Drug Discovery. 16(7). 472–486. 358 indexed citations

16.

Friedman, Allyson K., Barbara Juarez, Stacy M. Ku, et al.. (2016). KCNQ channel openers reverse depressive symptoms via an active resilience mechanism. Nature. 35 indexed citations

17.

Iosifescu, Dan V., James W. Murrough, Thilo Deckersbach, et al.. (2015). galantamine-er for cognitive deficits in bipolar disorder. Bipolar Disorders. 17. 1 indexed citations

18.

DeWilde, Kaitlin E., Cara F. Levitch, James W. Murrough, Sanjay J. Mathew, & Dan V. Iosifescu. (2015). The promise of ketamine for treatment‐resistant depression: current evidence and future directions. Annals of the New York Academy of Sciences. 1345(1). 47–58. 60 indexed citations

19.

Lener, Marc S., Prantik Kundu, Edmund Wong, et al.. (2015). Cortical abnormalities and association with symptom dimensions across the depressive spectrum. Journal of Affective Disorders. 190. 529–536. 43 indexed citations

20.

Iacoviello, Brian M., Gang Wu, Rany Abend, et al.. (2014). Attention Bias Variability and Symptoms of Posttraumatic Stress Disorder. Journal of Traumatic Stress. 27(2). 232–239. 138 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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