James G. Krueger

67.4k total citations · 27 hit papers
495 papers, 49.7k citations indexed

About

James G. Krueger is a scholar working on Immunology, Dermatology and Physiology. According to data from OpenAlex, James G. Krueger has authored 495 papers receiving a total of 49.7k indexed citations (citations by other indexed papers that have themselves been cited), including 311 papers in Immunology, 276 papers in Dermatology and 118 papers in Physiology. Recurrent topics in James G. Krueger's work include Psoriasis: Treatment and Pathogenesis (228 papers), Dermatology and Skin Diseases (218 papers) and Asthma and respiratory diseases (113 papers). James G. Krueger is often cited by papers focused on Psoriasis: Treatment and Pathogenesis (228 papers), Dermatology and Skin Diseases (218 papers) and Asthma and respiratory diseases (113 papers). James G. Krueger collaborates with scholars based in United States, Germany and Canada. James G. Krueger's co-authors include Michelle A. Lowes, Emma Guttman‐Yassky, Mayte Suárez‐Fariñas, A. Bowcock, Irma Cardinale, Judilyn Fuentes‐Duculan, Kristine Nograles, Lisa C. Zaba, Patricia Gilleaudeau and Toyoko Kikuchi and has published in prestigious journals such as Nature, New England Journal of Medicine and Cell.

In The Last Decade

James G. Krueger

478 papers receiving 48.5k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Pathogenesis and therapy of psoriasis

2007 1.4k citations James G. Krueger et al. profile →
Immunology of Psoriasis

2014 1.2k citations Mayte Suárez‐Fariñas, James G. Krueger et al. profile →
Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

2008 855 citations Judilyn Fuentes‐Duculan, Irma Cardinale et al. Journal of Investigative Dermatology profile →
Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.

1989 740 citations James G. Krueger et al. profile →
Progressive activation of TH2/TH22 cytokines and selective epidermal proteins characterizes acute and chronic atopic dermatitis

2012 740 citations Avner Shemer, Mayte Suárez‐Fariñas et al. Journal of Allergy and Clinical Immunology profile →
Increased Expression of Interleukin 23 p19 and p40 in Lesional Skin of Patients with Psoriasis Vulgaris

2004 738 citations James G. Krueger et al. profile →
Brodalumab, an Anti–Interleukin-17–Receptor Antibody for Psoriasis

2012 729 citations James G. Krueger et al. profile →
Psoriasis pathogenesis and the development of novel targeted immune therapies

2017 687 citations Jason E. Hawkes, James G. Krueger et al. Journal of Allergy and Clinical Immunology profile →
Th17 cytokines interleukin (IL)-17 and IL-22 modulate distinct inflammatory and keratinocyte-response pathways

2008 665 citations Emma Guttman‐Yassky, Judilyn Fuentes‐Duculan et al. profile →
Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses

2007 540 citations Irma Cardinale, Patricia Gilleaudeau et al. profile →
Psoriasis and Systemic Inflammatory Diseases: Potential Mechanistic Links between Skin Disease and Co-Morbid Conditions

2010 538 citations James G. Krueger et al. Journal of Investigative Dermatology profile →
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

2017 517 citations James G. Krueger et al. profile →
Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis

2010 513 citations Emma Guttman‐Yassky, Mayte Suárez‐Fariñas et al. Journal of Investigative Dermatology profile →
IL-22–producing “T22” T cells account for upregulated IL-22 in atopic dermatitis despite reduced IL-17–producing TH17 T cells

2009 489 citations Avner Shemer, Judilyn Fuentes‐Duculan et al. Journal of Allergy and Clinical Immunology profile →
The Asian atopic dermatitis phenotype combines features of atopic dermatitis and psoriasis with increased TH17 polarization

2015 489 citations Shinji Noda, Mayte Suárez‐Fariñas et al. Journal of Allergy and Clinical Immunology profile →
Dupilumab progressively improves systemic and cutaneous abnormalities in patients with atopic dermatitis

2018 477 citations Emma Guttman‐Yassky, Mayte Suárez‐Fariñas et al. Journal of Allergy and Clinical Immunology profile →
The immunogenetics of Psoriasis: A comprehensive review

2015 457 citations James G. Krueger et al. profile →
Atopic dermatitis endotypes and implications for targeted therapeutics

2019 438 citations Tali Czarnowicki, Helen He et al. Journal of Allergy and Clinical Immunology profile →
Discovery of the IL-23/IL-17 Signaling Pathway and the Treatment of Psoriasis

2018 417 citations Jason E. Hawkes, James G. Krueger et al. profile →
Risankizumab versus Ustekinumab for Moderate-to-Severe Plaque Psoriasis

2017 392 citations Andrew Blauvelt, James G. Krueger et al. profile →
Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis

2013 379 citations Mayte Suárez‐Fariñas, Avner Shemer et al. Journal of Allergy and Clinical Immunology profile →
A prospective phase III, randomized, double‐blind, placebo‐controlled study of brodalumab in patients with moderate‐to‐severe plaque psoriasis

2016 376 citations Andrew Blauvelt, James G. Krueger et al. profile →
Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)

2005 373 citations Judilyn Fuentes‐Duculan, Irma Cardinale et al. profile →
Dupilumab improves the molecular signature in skin of patients with moderate-to-severe atopic dermatitis

2014 359 citations Mayte Suárez‐Fariñas, Irma Cardinale et al. Journal of Allergy and Clinical Immunology profile →
Single-cell transcriptome analysis of human skin identifies novel fibroblast subpopulation and enrichment of immune subsets in atopic dermatitis

2020 310 citations Helen He, Hyun Je Kim et al. Journal of Allergy and Clinical Immunology profile →
Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase 3 trial

2021 170 citations James G. Krueger, Andrew Blauvelt et al. profile →
IL-23 past, present, and future: a roadmap to advancing IL-23 science and therapy

2024 42 citations James G. Krueger, Kilian Eyerich et al. Frontiers in Immunology profile →

Peers

Countries citing papers authored by James G. Krueger

Since Specialization

Citations

This map shows the geographic impact of James G. Krueger's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by James G. Krueger with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites James G. Krueger more than expected).

Fields of papers citing papers by James G. Krueger

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by James G. Krueger. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by James G. Krueger. The network helps show where James G. Krueger may publish in the future.

Co-authorship network of co-authors of James G. Krueger

This figure shows the co-authorship network connecting the top 25 collaborators of James G. Krueger. A scholar is included among the top collaborators of James G. Krueger based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with James G. Krueger. James G. Krueger is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Orismilast, a Potent and Selective PDE4B /D Inhibitor, Reduces Protein Levels of Key Disease Driving Cytokines in the Skin of Patients With Plaque Psoriasis 2025 ·Experimental Dermatology ·Richard B. Warren, Anne Weiss, Jakob Felding, Morten Otto Alexander Sommer, Sandra Garcet, James G. Krueger	0
2	265 Modulation of disease-central cytokine pathways with TAK-279, a highly selective oral tyrosine kinase 2 (TYK2) inhibitor, defines clinical response in patients with psoriasis 2024 ·Journal of Investigative Dermatology ·James G. Krueger, Sandra Garcet, (unknown), Sanjay Kumar, Jie Tang, John Blau, Yan Zhao, Weidong Zhang, Bhaskar Saha, (unknown), (unknown), Paresh Thakker, Anindo Choudhury	1
3	Eosinophils in hidradenitis suppurativa patients exhibit pro‐inflammatory traits, implicating a potential pathogenic role in the disease 2024 ·Experimental Dermatology ·Yael Renert‐Yuval, Juana Gonzalez, (unknown), Samuel C. Williams, (unknown), James G. Krueger	1
4	Evolution of pathologic B‐cell subsets and serum environment‐specific sIgEs in patients with atopic dermatitis and controls, from infancy to adulthood 2024 ·Allergy ·Tali Czarnowicki, (unknown), Kazuhiko Yamamura, Joseph Han, Helen He, Ana B. Pavel, Jacob W. Glickman, Taylor Erickson, Yeriel Estrada, James G. Krueger, Stephanie M. Rangel, Amy S. Paller, Emma Guttman‐Yassky	1
5	Psoriasis improvements and inflammatory biomarker normalization with secukinumab: the randomized ObePso-S study 2023 ·Journal of Dermatological Science ·Andrew Blauvelt, David M. Pariser, Stephen K. Tyring, Jerry Bagel, Andrew Alexis, Jennifer Soung, April W. Armstrong, Elisa Muscianisi, Farid Kianifard, Jennifer Steadman, (unknown), Sandra Garcet, James G. Krueger	11
6	Spesolimab for Hidradenitis Suppurativa: A Proof-of-Concept Study 2023 ·SKIN The Journal of Cutaneous Medicine ·Afsáneh Alavi, Errol P. Prens, Alexa B. Kimball, James G. Krueger, (unknown), Hui Wang, (unknown), (unknown), Christos C. Zouboulis	6
7	230 Immunosuppression causes dynamic changes in expression QTLs in psoriatic skin 2023 ·Journal of Investigative Dermatology ·Laura A. Cooney, Qian Xiao, Jason A. Mears, (unknown), (unknown), Yuriy Baglaenko, Noha Lim, Kristina M. Harris, Mark S. Anderson, David A. Fox, Dawn E. Smilek, James G. Krueger, Soumya Raychaudhuri	1
8	Investigation of plaque psoriasis relapse after secukinumab withdrawal in patients from two phase III studies 2023 ·Clinical and Experimental Dermatology ·Mark Lebwohl, Lars Iversen, Liv Eidsmo, James G. Krueger, Mayte Suárez‐Fariñas, Lewis E. Tomalin, Frank Kolbinger, R. You, M. Milutinovic	10
9	The role of the interleukin-36 axis in generalized pustular psoriasis: a review of the mechanism of action of spesolimab 2023 ·Frontiers in Immunology ·Jason E. Hawkes, Sudha Visvanathan, James G. Krueger	12
10	Genomic Profiling of the Overlap Phenotype between Psoriasis and Atopic Dermatitis 2023 ·Journal of Investigative Dermatology ·Jeong Eun Kim, (unknown), (unknown), (unknown), (unknown), James G. Krueger, Jaehwan Kim	17
11	Modulation of Inflammatory Proteins in Serum May Reflect Cutaneous Immune Responses in Cancer Immunotherapy 2023 ·SHILAP Revista de lepidopterología ·Joseph Han, Joel Corrêa da Rosa, (unknown), (unknown), (unknown), (unknown), Aatman Shah, Yeriel Estrada, Jonathan Ungar, Kavita Y. Sarin, James G. Krueger, Nicholas Gulati	1
12	769 GUSELKUMAB, AN IL-23P19 SUBUNIT-SPECIFIC MONOCLONAL ANTIBODY, BINDS CD64+ MYELOID CELLS AND POTENTLY NEUTRALIZES IL-23 PRODUCED FROM THE SAME CELLS 2023 ·Gastroenterology ·María T. Abreu, Raja Atreya, James G. Krueger, Kilian Eyerich, Kacey L. Sachen, (unknown), Deepa Hammaker, (unknown), Eilyn R. Lacy, (unknown), (unknown), M. Merle Elloso, Christopher T. Ritchlin, Iain B. McInnes, Matthieu Allez, Anne M. Fourie	0
13	Contribution of fibroblasts to tunnel formation and inflammation in hidradenitis suppurativa/ acne inversa 2019 ·Experimental Dermatology ·John W. Frew, Kristina Navrazhina, (unknown), Ping Lu, James G. Krueger	42
14	Evolution of pathologic T-cell subsets in patients with atopic dermatitis from infancy to adulthood 2019 ·Journal of Allergy and Clinical Immunology ·Tali Czarnowicki, Helen He, Talia Canter, Joseph Han, Rachel Lefferdink, Taylor Erickson, Stephanie M. Rangel, Naoya Kameyama, Hyun Je Kim, Ana B. Pavel, Yeriel Estrada, James G. Krueger, Amy S. Paller, Emma Guttman‐Yassky	85
15	Early-onset pediatric atopic dermatitis is characterized by TH2/TH17/TH22-centered inflammation and lipid alterations 2018 ·Journal of Allergy and Clinical Immunology ·Patrick M. Brunner, Ariel Israel, Ning Zhang, Alexandra Leonard, Huei‐Chi Wen, Thy Huynh, Gary Tran, Sarah Lyon, (unknown), Supriya Immaneni, Annette Wagner, Xiuzhong Zheng, Yeriel Estrada, Hui Xu, James G. Krueger, Amy S. Paller, Emma Guttman‐Yassky	189
16	Efficacy and safety of ustekinumab treatment in adults with moderate‐to‐severe atopic dermatitis 2016 ·Experimental Dermatology ·Saakshi Khattri, Patrick M. Brunner, Sandra Garcet, Robert Finney, Steven R. Cohen, Margeaux Oliva, Riana Dutt, Judilyn Fuentes‐Duculan, Xiuzhong Zheng, Xuan Li, Kathleen M. Bonifacio, Norma Kunjravia, Israel Coats, Inna Cueto, Patricia Gilleaudeau, Mary Sullivan‐Whalen, Mayte Suárez‐Fariñas, James G. Krueger, Emma Guttman‐Yassky	170
17	Alterations in B-cell subsets in pediatric patients with early atopic dermatitis 2016 ·Journal of Allergy and Clinical Immunology ·Tali Czarnowicki, Hitokazu Esaki, Juana Gonzalez, Yael Renert‐Yuval, Patrick M. Brunner, Margeaux Oliva, Yeriel Estrada, Hui Xu, Xiuzhong Zheng, (unknown), Isabel Haugh, Thy Huynh, Sarah Lyon, Gary Tran, Hugh A. Sampson, Mayte Suárez‐Fariñas, James G. Krueger, Emma Guttman‐Yassky, Amy S. Paller	47
18	Early pediatric atopic dermatitis shows only a cutaneous lymphocyte antigen (CLA)+ TH2/TH1 cell imbalance, whereas adults acquire CLA+ TH22/TC22 cell subsets 2015 ·Journal of Allergy and Clinical Immunology ·Tali Czarnowicki, Hitokazu Esaki, Juana Gonzalez, Dana Malajian, Avner Shemer, Shinji Noda, (unknown), (unknown), (unknown), Lauren Becker, Yeriel Estrada, Hui Xu, Xiuzhong Zheng, Mayte Suárez‐Fariñas, James G. Krueger, Amy S. Paller, Emma Guttman‐Yassky	171
19	IL32 Is Progressively Expressed in Mycosis Fungoides Independent of Helper T-cell 2 and Helper T-cell 9 Polarization 2014 ·Cancer Immunology Research ·Hanako Ohmatsu, Daniel Humme, Nicholas Gulati, Juana Gonzalez, Markus Möbs, Mayte Suárez‐Fariñas, Irma Cardinale, Hiroshi Mitsui, Emma Guttman‐Yassky, Wolfram Sterry, James G. Krueger	17
20	HER1/EGFR Inhibitor-Associated Rash: Future Directions for Management and Investigation Outcomes from the HER1/EGFR Inhibitor Rash Management Forum 2005 ·The Oncologist ·Román Pérez-Soler, Jean Pierre Delord, Allan C. Halpern, Karen Kelly, James G. Krueger, B. Massuti Sureda, Joachim von Pawel, Jennifer S. Temel, Salvatore Siena, Denis Soulières, Leonard B. Saltz, William D. James	215

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